Chromosome aberrations determined by sFISH and G-banding in lymphocytes from workers with internal deposits of plutonium

References

• Ainsbury EA, Bakhanova E, Barquinero JF, Brai M, Chumak V, Correcher V, Darroudi F, Fattibene P, Gruel G, Guclu I, et al. 2011. Review of retrospective dosimetry techniques for external ionising radiation exposures. Radiat Prot Dosim. 147:573–592.
   PubMed Web of Science ®Google Scholar
• Ainsbury EA, Moquet J, Rothkamm K, Darroudi F, Vozilova A, Degteva M, Azizova TV, Lloyd DC, Harrison J. 2014. What radiation dose does the FISH translocation assay measure in cases of incorporated radionuclides for the Southern Urals populations? Radiat Prot Dosim. 159:1–4.
   Web of Science ®Google Scholar
• Anderson RM, Marsden SJ, Paice SJ, Bristow AE, Kadhim MA, Griffin CS, Goodhead DT. 2003. Transmissible and nontransmissible complex chromosome aberrations characterized by three-color and mFISH define a biomarker of exposure to high-LET alpha particles. Radiat Res. 159:40–48.
   PubMed Web of Science ®Google Scholar
• Anderson RM, Marsden SJ, Wright EG, Kadhim MA, Goodhead DT, Griffin CS. 2000. Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles. Int J Radiat Biol. 76:31–42.
   PubMed Web of Science ®Google Scholar
• Anderson RM, Papworth DG, Stevens DL, Sumption ND, Goodhead DT. 2006. Increased complexity of radiation-induced chromosome aberrations consistent with a mechanism of sequential formation. Cytogenet Genome Res. 112:35–44.
   PubMed Web of Science ®Google Scholar
• Anderson RM, Stevens DL, Goodhead DT. 2002. m-FISH analysis shows that complex chromosome aberrations induced by alpha-particle tracks are cumulative products of localized rearrangements. Proc Natl Acad Sci USA. 99:12167–12172.
   PubMed Web of Science ®Google Scholar
• Anderson RM, Tsepenko VV, Gasteva GN, Molokanov AA, Sevan’kaev AV, Goodhead DT. 2005. mFISH analysis reveals complexity of chromosome aberrations in individuals occupationally exposed to internal plutonium: A pilot study to assess the relevance of complex aberrations as biomarkers of exposure to high-LET alpha particles. Radiat Res. 163:26–35.
   PubMed Web of Science ®Google Scholar
• Barquinero JF, Stephan G, Schmid E. 2004. Effect of americium-241 alpha-particles on the dose-response of chromosome aberrations in human lymphocytes analysed by fluorescence in situ hybridization. Int J Radiat Biol. 80:155–164.
   PubMed Web of Science ®Google Scholar
• Bhatti P, Yong LC, Doody MM, Preston DL, Kampa DM, Ramsey MJ, Ward EM, Edwards AA, Ron E, Tucker JD, et al. 2004. Diagnostic X-ray examinations and increased chromosome translocations: Evidence from three studies. Radiat Environ Biophys. 49:685–692.
   Web of Science ®Google Scholar
• Bonassi S, Norppa H, Ceppi M, Stromberg U, Vermeulen R, Znaor A, Cebulska-Wasilewska A, Fabianova E, Fucic A, Gundy S, et al. 2008. Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: Results from a pooled cohort study of 22358 subjects in 11 countries. Carcinogenesis. 29:1178–1183.
   PubMed Web of Science ®Google Scholar
• Bothwell AM, Whitehouse CA, Tawn EJ. 2000. The application of FISH for chromosome aberration analysis in relation to radiation exposure. Radiat Prot Dosim. 88:7–14.
   Web of Science ®Google Scholar
• Brandom WF, Archer PG, Bloom AD, Archer VE, Bistline RW, Saccomanno G. 1979. Chromosome changes in somatic cells of workers with internal depositions of plutonium. In: Biological implications of radionuclides from nuclear industries, Vol II. IAEA-SM-237/38. Vienna: International Atomic Energy Agency. pp. 195–220.
   Google Scholar
• Brandom WF, McGavran L, Bistline RW, Bloom AD. 1990. Sister chromatid exchanges and chromosome aberration frequencies in plutonium workers. Int J Radiat Biol. 58:195–207.
   PubMed Web of Science ®Google Scholar
• Brenner DJ, Sachs RK. 1994. Chromosomal ‘fingerprints’ of prior exposure to densely ionizing radiation. Radiat Res. 140:134–142.
   PubMed Web of Science ®Google Scholar
• Curwen GB, Sotnik NV, Cadwell KK, Azizova TV, Hill MA, Tawn EJ. 2015. Chromosome aberrations in workers with exposure to α-particle radiation from internal deposits of plutonium – expectations from in vitro studies and comparisons with workers with predominantly external γ-radiation exposure. Radiat Environ Biophys. 54:195–206.
   PubMed Web of Science ®Google Scholar
• Curwen GB, Tawn EJ, Cadwell KK, Guyatt L, Thompson J, Hill MA. 2012. mFISH analysis of chromosome aberrations induced in vitro by alpha-particle radiation: Examination of dose-response relationships. Radiat Res. 178:414–424.
   PubMed Web of Science ®Google Scholar
• Durante M, Bedford JS, Chen DJ, Conrad S, Cornforth MN, Natarajan AT, van Gent DC, Obe G. 2013. From DNA damage to chromosome aberrations: Joining the break. Mutat Res. 756:5–13.
   PubMed Web of Science ®Google Scholar
• Edwards AA, Lindholm C, Darroudi F, Stephan G, Romm H, Barquinero J, Barrios L, Caballin MR, Roy L, Whitehouse CA, et al. 2005. Review of translocations detected by FISH for retrospective biological dosimetry applications. Radiat Prot Dosim. 113:396–402.
   PubMed Web of Science ®Google Scholar
• Edwards AA, Szluinska M, Lloyd DC. 2007. Reconstruction of doses from ionizing radiation using fluorescence in situ hybridization techniques. Br J Radiol. 80(Spec. 1):S63–S67.
   Google Scholar
• Griffin CS, Marsden SJ, Stevens DL, Simpson P, Savage JR. 1995. Frequencies of complex chromosome exchange aberrations induced by 238Pu alpha-particles and detected by fluorescence in situ hybridization using single chromosome-specific probes. Int J Radiat Biol. 67:431–439.
   PubMed Web of Science ®Google Scholar
• Hande MP, Azizova TV, Geard CR, Burak LE, Mitchell CR, Khokhryakov VF, Vasilenko EK, Brenner DJ. 2003. Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome. Am J Hum Genet. 72:1162–1170.
   PubMed Web of Science ®Google Scholar
• Hill MA, Griffin CS, Pyke EL, Stevens DL. 2011. Chromosome aberration induction is dependent on the spatial distribution of energy deposition through a cell nucleus. Radiat Prot Dosim. 143:172–176.
   PubMed Web of Science ®Google Scholar
• International Atomic Energy Agency (IAEA). 2011. Cytogenetic dosimetry: Applications in preparedness for and response to radiation emergencies. Vienna: IAEA-EPR.
   Google Scholar
• International Commission on Radiological Protection (ICRP). 1993. Age-dependant doses to members of the public from intake of radionuclides: Part 2. Ingestion dose coefficients, Publication 67 Ann ICRP 23 (3/4).
   Google Scholar
• International Commission on Radiological Protection (ICRP). 2007. The 2007 recommendations of the International Commission on Radiological Protection, Publication 103 Ann ICRP 37(2–4).
   Google Scholar
• Kite AV, Britcher AR. 1996. Uncertainties in recorded photon radiation doses at Sellafield. Radiat Prot Dosim. 67:23–32.
   Web of Science ®Google Scholar
• Leggett RW, Eckerman KF, Khokhryakov VF, Suslova KG, Krahenbuhl MP, Miller SC. 2005. Mayak worker study: An improved biokinetic model for reconstructing doses from internally deposited plutonium. Radiat Res. 164:111–122.
   PubMed Web of Science ®Google Scholar
• Livingston GK, Falk RB, Schmid E. 2006. Effect of occupational radiation exposures on chromosome aberration rates in former plutonium workers. Radiat Res. 166:89–97.
   PubMed Web of Science ®Google Scholar
• Lucas JN, Awa A, Straume T, Poggensee M, Kodama Y, Nakano M, Ohtaki K, Weier HU, Pinkel D, Gray J, et al. 1992. Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. Int J Radiat Biol. 62:53–63.
   PubMed Web of Science ®Google Scholar
• Mitchell CR, Azizova TV, Hande MP, Burak LE, Tsakok JM, Khokhryakov VF, Geard CR, Brenner DJ. 2004. Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals. Radiat Res. 162:257–263.
   PubMed Web of Science ®Google Scholar
• Moquet JE, Fernandez JL, Edwards AA, Lloyd DC. 2001. Lymphocyte chromosomal aberrations and their complexity induced in vitro by plutonium-239 alpha-particles and detected by FISH. Cell Mol Biol. 47:549–556.
   PubMed Web of Science ®Google Scholar
• Omar RZ, Barber JA, Smith PG. 1999. Cancer mortality and morbidity among plutonium workers at the Sellafield plant of British Nuclear Fuels. Br J Cancer. 79:1288–301.
   PubMed Web of Science ®Google Scholar
• Pignalosa D, Durante M. 2011. Cellular effects of energetic heavy ions: From DNA breaks to chromosomal rearrangements. Radiat Prot Dosim. 143:391–393.
   PubMed Web of Science ®Google Scholar
• Riddell AE, Birchall A, Puncher M, Efimov A, Vostrotin V. 2015. Report on the development and validation of plutonium dose assessment systems for epidemiological research In: SOLO Project Deliverable 3.3.1. European Union 7th Framework Programme for Research.
   Google Scholar
• Salassidis K, Braselmann H, Okladnikova ND, Pressl S, Stephan G, Snigiryova G, Bauchinger M. 1998. Analysis of symmetrical translocations for retrospective biodosimetry in radiation workers of the Mayak nuclear-industrial complex (Southern Urals) using FISH-chromosome painting. Int J Radiat Biol. 74:431–439.
   PubMed Web of Science ®Google Scholar
• Seabright M. 1971. A rapid banding technique for human chromosomes. Lancet. 2:971–972.
   PubMed Web of Science ®Google Scholar
• Sigurdson AJ, Ha M, Hauptmann M, Bhatti P, Sram RJ, Beskid O, Tawn EJ, Whitehouse CA, Lindholm C, Nakano M, et al. 2008. International study of factors affecting human chromosome translocations. Mutat Res. 652:112–121.
   PubMed Web of Science ®Google Scholar
• Sotnik NV, Osovets SV, Scherthan H, Azizova TV. 2014. mFISH analysis of chromosome aberrations in workers occupationally exposed to mixed radiation. Radiat Environ Biophys. 53:347–354.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Curwen GB, Rees GS, Jonas P. 2015a. Germline minisatellite mutations in workers occupationally exposed to radiation at the Sellafield nuclear facility. J Radiol Prot. 30:21–36.
   Web of Science ®Google Scholar
• Tawn EJ, Curwen GB, Jonas P, Gillies M, Hodgson L, Cadwell KK. 2015b. Chromosome aberrations determined by FISH in radiation workers from the Sellafield Nuclear Facility. Radiat Res. 184:296–303.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Hall JW, Schofield GB. 1985. Chromosome studies in plutonium workers. Int J Radiat Biol. 47:599–610.
   Web of Science ®Google Scholar
• Tawn EJ, Whitehouse CA. 2001. Frequencies of chromosome aberrations in a control population determined by G banding. Mutat Res. 490:171–177.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Whitehouse CA. 2005. Chromosome intra- and inter-changes determined by G-banding in radiation workers with in vivo exposure to plutonium. J Radiol Prot. 25:83–88.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Whitehouse CA, De Ruyck K, Hodgson L, Vandenbulcke K, Thierens H. 2007. The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation. Radiat Res. 168:666–674.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Whitehouse CA, Holdsworth D, De Ruyck K, Vandenbulcke K, Thierens H. 2008. mBAND analysis of chromosome aberrations in lymphocytes exposed in vitro to alpha-particles and gamma-rays. Int J Radiat Biol. 84:447–453.
   PubMed Web of Science ®Google Scholar
• Tawn EJ, Whitehouse CA, Riddell AE. 2006. FISH chromosome analysis of plutonium workers from the Sellafield nuclear facility. Radiat Res. 165:592–597.
   PubMed Web of Science ®Google Scholar
• Thierens H, De Ruyck K, Vral A, de Gelder V, Whitehouse CA, Tawn EJ, Boesman I. 2005. Cytogenetic biodosimetry of an accidental exposure of a radiological worker using multiple assays. Radiat Prot Dosim. 113:408–414.
   PubMed Web of Science ®Google Scholar
• Tucker JD, Morgan WF, Awa AA, Bauchinger M, Blakey D, Cornforth MN, Littlefield LG, Natarajan AT, Shasserre C. 1995. PAINT: A proposed nomenclature for structural aberrations detected by whole chromosome painting. Mutat Res. 347:21–24.
   PubMed Web of Science ®Google Scholar
• Tucker JD, Tawn EJ, Holdsworth D, Morris S, Langlois R, Ramsey MJ, Kato P, Boice JD Jr, Tarone RE, Jensen RH. 1997. Biological dosimetry of radiation workers at the Sellafield nuclear facility. Radiat Res. 148:216–226.
   PubMed Web of Science ®Google Scholar
• Vozilova AV, Shagina NB, Degteva MO, Edwards AA, Ainsbury EA, Moquet JE, Hone P, Lloyd DC, Fomina JN, Darroudi F. 2012. Preliminary FISH-based assessment of external dose for residents exposed on the Techa River. Radiat Res. 177:84–91.
   PubMed Web of Science ®Google Scholar
• Whitehouse CA, Edwards AA, Tawn EJ, Stephan G, Oestreicher U, Moquet JE, Lloyd DC, Roy L, Voisin P, Lindholm C, et al. 2005. Translocation yields in peripheral blood lymphocytes from control populations. Int J Radiat Biol. 81:139–145.
   PubMed Web of Science ®Google Scholar
• Whitehouse CA, Tawn EJ, Riddell AE. 1998. Chromosome aberrations in radiation workers with internal deposits of plutonium. Radiat Res. 150:459–468.
   PubMed Web of Science ®Google Scholar