The food additives inulin and stevioside counteract oxidative stress

References

• Aebi H. 1984. Catalase in vitro. Meth Enzymol. 105:121–126.
   PubMed Web of Science ®Google Scholar
• Alexander RW, Cooper T. 1995. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: A new perspective. Hypertension. 25:155–161.
   PubMed Web of Science ®Google Scholar
• Bohnert HJ, Jensen RG. 1996. Strategies for engineering water stress tolerance in plants. Trends Biotechnol. 14:89–97.
   Web of Science ®Google Scholar
• Bolouri-Moghaddam M-R, Le Roy K, Xiang L, Rolland F, Van den Ende W. 2010. Sugar signalling and antioxidant network connections in plant cells. FEBS J. 277:2022–2037.
   PubMed Web of Science ®Google Scholar
• Brandle JE, Telmer PG. 2007. Steviol glycoside biosynthesis. Phytochemistry. 68:1855–1863.
   PubMed Web of Science ®Google Scholar
• Brighenti F. 2007. Dietary fructans and serum triacylglycerols: A meta-analysis of randomized controlled trials. J Nutr. 137:2552S–2556S.
   PubMed Web of Science ®Google Scholar
• Busserolles J, Gueux E, Rock E, Demigne C, Mazur A, Rayssiguier Y. 2003. Oligofructose protects against the hypertriglyceridemic and pro-oxidative effects of a high fructose diet in rats. J Nutr. 133:1903–1908.
   PubMed Web of Science ®Google Scholar
• Chatsudthipong V, Muanprasat C. 2009. Stevioside and related compounds: Therapeutic benefits beyond sweetness. Pharmacol Therapeut. 121:41–54.
   PubMed Web of Science ®Google Scholar
• Chen H, Zhang M, Qu Z, Xie B. 2008. Antioxidant activities of different fractions of polysaccharide conjugates from green tea (Camellia Sinensis). Int J Biol Macromol. 2:559–563.
   Google Scholar
• Crowe JH. 2007. Trehalose as a “chemical chaperone”: fact and fantasy. Adv Exp Med Biol. 594:143–158.
   PubMed Web of Science ®Google Scholar
• Clos JF, DuBois GE, Prakash I. 2008. Photostability of rebaudioside A and stevioside in beverages. J Agric Food Chem. 56:8507–8513.
   PubMed Web of Science ®Google Scholar
• De Gara L, de Pinto MC, Moliterni VMC, D'Egidio MG. 2003. Redox regulation and storage processes during maturation in kernels of Triticum durum. J Exp Bot. 54:249–258.
   PubMed Web of Science ®Google Scholar
• De Preter V, Vanhoutte T, Huys G, Swings J, De Vuyst L, Rutgeerts P, Verbeke K. 2007. Effects of Lactobacillus casei Shirota, Bifidobacterium breve, and oligofructose-enriched inulin on colonic nitrogen-protein metabolism in healthy humans. Am J Physiol Gastrointest Liver Physiol. 292:G358–G368.
   PubMed Web of Science ®Google Scholar
• Dunand C, Crévecoeur M, Penel C. 2007. Distribution of superoxide and hydrogen peroxide in Arabidopsis root and their influence on root development: Possible interaction with peroxidases. New Phytol. 174:332–341.
   PubMed Web of Science ®Google Scholar
• Fernie AR, Martinoia E. 2009. Malate. Jack of all trades or master of a few?. Phytochemistry. 7:828–832.
   Google Scholar
• Gao T, Bi H, Ma S, Lu J. 2010. Structure elucidation and antioxidant activity of a novel α-(1 → 3),(1 → 4)-d-glucan from Aconitum kusnezoffii Reichb. Int J Biol Macromol. 45:85–90.
   Google Scholar
• Geeraert B, Crombe F, Hulsmans M, Benhabiles N, Geuns J, Holvoet P. 2010. Stevioside inhibits atherosclerosis by improving insulin signaling and antioxidant defense in obese insulin-resistant mice. Int J Obesity. 34:569–577.
   Web of Science ®Google Scholar
• Geuns JMC. 2003. Stevioside. Phytochemistry. 64:913–921.
   PubMed Web of Science ®Google Scholar
• Geuns JMC. Steviol glucuronide as excretion product of stevioside in human volunteers: Lack of carcinogenic properties of steviol glycosides and steviol. In Sweetness and Sweeteners, American Chemical Society, Washington DC, USA. 2008a573–595.
   Google Scholar
• Geuns JMC. A safe sweetener and possible new drug for the treatment of the metabolic syndrome. In Sweetness and Sweeteners, American Chemical Society, Washington DC, USA. 2008b596–614.
   Google Scholar
• Giannopolitis CN, Ries SK. 1977. Superoxide dismutase. I. Occurrence in higher plants. Plant Physiol. 59:309–314.
   PubMed Web of Science ®Google Scholar
• Goyal S, Goyal R. 2010. Stevia (Stevia rebaudiana) a bio-sweetener: A review. Int J Food Sci Nutr. 61:1–10.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. 2007. Free Radicals in Biology and Medicine. New Yr: Oxford University Press.
   Google Scholar
• Kanner J, Lapidot T. 2001. The stomach as a bioreactor: Dietary lipid peroxidation in the gastric fluid and the effect of plant-derived antioxidants. Free Radic Biol Med. 31:1388–1395.
   PubMed Web of Science ®Google Scholar
• Kawakami A, Sato Y, Yoshida M. 2008. Genetic engineering of rice capable of synthesizing fructans and enhancing chilling tolerance. J Exp Bot. 59:803–814.
   PubMed Web of Science ®Google Scholar
• Korycka-Dahl MB, Richardson T, Foote CS. 1978. Activated oxygen species and oxidation of food constituents. Crit Rev Food Sci Nutr. 10:209–241.
   Web of Science ®Google Scholar
• Kroyer G. 2010. Stevioside and Stevia-sweetener in food: Application, stability and interaction with food ingredients. J Verbr Lebensm. 5:225–229.
   Google Scholar
• Li HJ, Yang AF, Zhang XC, Gao F, Zhang JR. Improving freezing tolerance of transgenic tobacco expressing sucrose: sucrose 1-fructosyltransferase gene from Lactuca sativa. Plant Cell Tissue Organ Cult. 2007a; 89:37–48.
   Web of Science ®Google Scholar
• Li X-M, Shi Y-H, Wang F, Wang H-S, Le G-W. In vitro free radical scavenging activities and effect of synthetic oligosaccharides on antioxidant enzymes and lipid peroxidation in aged mice. J Pharm Biomed Anal. 2007b; 43:364–370.
   PubMed Web of Science ®Google Scholar
• Lim YJ, Lee EH, Kang TH, Ha SK, Oh MS, Kim SM, Yoon TJ, Kang C, Park JH, Kim SY. 2009. Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues. Arch Pharm Res. 32:367–373.
   PubMed Web of Science ®Google Scholar
• Lomax AR, Calder PC. 2009. Prebiotics, immune function, infection and inflammation: A review of the evidence. Br J Nutr. 101:633–658.
   PubMed Web of Science ®Google Scholar
• Majer P, Stoyanova S, Hideg É. 2010. Do leaf total antioxidant capacities (TAC) reflect specific antioxidant potentials? A comparison of TAC and reactive oxygen scavenging in tobacco leaf extracts. J Photoch Photobio B. 100:38–43.
   PubMed Web of Science ®Google Scholar
• Manno D, Filippo E, Serra A, Negro C, De Bellis L, Miceli A. 2009. The influence of inulin addition on the morphological and structural properties of durum wheat pasta. Int J Food Sci Technol. 44:218–2224.
   Web of Science ®Google Scholar
• McCord JM, Fridovich I. 1969. Superoxide dismutase: An enzymic function for erythrocuprein (hemocuprein). J Biol Chem. 244:6049–6055.
   PubMed Web of Science ®Google Scholar
• Mittler R, Vanderauwera S, Gollery M, Van Breusegem F. 2004. Reactive oxygen gene network of plants. Trends Plant Sci. 9:490–498.
   PubMed Web of Science ®Google Scholar
• Morelli R, Russo-Volpe S, Bruno N, Scalzo RL. 2003. Fenton-dependent damage to carbohydrates: Free radical scavenging activity of some simple sugars. J Agric Food Chem. 51:7418–7425.
   PubMed Web of Science ®Google Scholar
• Nishizawa A, Yukinori Y, Shigeoka S. 2008. Galactinol and raffinose as a novel function to protect plants from oxidative damage. Plant Physiol. 147:1251–1263.
   PubMed Web of Science ®Google Scholar
• Parejo I, Viladomat F, Bastida J, Codina C. 2001. A single extraction step in the quantitative analysis of arbutin in bearberry (Arctostaphylos uva-ursi) leaves by high-performance liquid chromatography. Phytochem Anal. 12:336–339.
   PubMed Web of Science ®Google Scholar
• Parvanova D, Ivanov S, Konstantinova T, Karanov E, Atanassov A, Tsvetkov T, Alexieva V, Djilianov D. 2004. Transgenic tobacco plants accumulating osmolytes show reduced oxidative damage under freezing stress. Plant Physiol Biochem. 42:57–63.
   PubMed Web of Science ®Google Scholar
• Parnell JA, Reimer RA. 2009. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am J Clin Nutr. 89:1751–1759.
   PubMed Web of Science ®Google Scholar
• Puchau B, Zulet M, de Echavarri A, Hermsdorff H, Martinez J. 2010. Dietary total antioxidant capacity is negatively associated with some metabolic syndrome features in healthy young adults. Nutrition. 26:534–541.
   PubMed Web of Science ®Google Scholar
• Rault-Nania M-H, Demougeot C, Gueux E, Berthelot A, Dzimira S, Rayssiguier Y, Rock E, Mazur A. 2008. Inulin supplementation prevents high fructose diet-induced hypertension in rats. Clin Nutr. 27:276–282.
   PubMed Web of Science ®Google Scholar
• Renuka B, Kulkarni S, Vijayanand G. 2009. Fructooligosaccharide fortification of selected fruit juice beverages: Effect on the quality characteristics. LWT Food Sci Technol. 42:1031–1033.
   Web of Science ®Google Scholar
• Roberfroid M. 2007. Prebiotics: The concept revisited. J Nutr. 137:830S–837S.
   PubMed Web of Science ®Google Scholar
• Roberfroid M, Gibson MR, Delzenne N. 1993. The biochemistry of oligofructose, a nondigestible fiber: An approach to calculate its caloric value. Nutr Rev. 51:137–146.
   PubMed Web of Science ®Google Scholar
• Sauer J, Richter KK, Pool-Zobel BL. 2007. Products formed during fermentation of the prebiotic inulin with human gut flora enhance expression of biotransformation genes in human primary colon cells. Br J Nutr. 97:928–938.
   PubMed Web of Science ®Google Scholar
• Scholz-Ahrens KE, Ade P, Marten B, Weber P, Timm W, Açil Y, Glüer CC, Schrezenmeir J. 2007. Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. J Nutr. 137:838S–846S.
   PubMed Web of Science ®Google Scholar
• Shen B, Jensen RC, Bohnert HJ. Increased resistance to oxidative stress in transgenic plants by targeting mannitol biosynthesis to chloroplasts. Plant Physiol. 1997a; 113:1177–1183.
   PubMed Web of Science ®Google Scholar
• Shen B, Jensen RC, Bohnert HJ. Mannitol protects against oxidation by hydroxyl radicals. Plant Physiol. 1997b; 115:527–532.
   PubMed Web of Science ®Google Scholar
• Shoaf K, Mulvey GL, Armstrong GD, Hutkins RW. 2006. Prebiotic galactooligosaccharides reduce adherence of enteropathogenic Escherichia coli to tissue culture cells. Infect Immun. 74:6920–6928.
   PubMed Web of Science ®Google Scholar
• Smirnoff N, Cumbes QJ. 1989. Hydroxyl radical scavenging activity of compatible solutes. Phytochemistry. 28:1057–1060.
   Web of Science ®Google Scholar
• Šnyrychová I, Hideg É. 2007. The first application of terephthalate fluorescence for highly selective detection of hydroxyl radicals in thylakoid membranes. Funct Plant Biol. 34:1105–1111.
   Web of Science ®Google Scholar
• Sonnenburg ED, Zheng H, Joglekar P, Higginbottom SK, Firbank SJ, Bolam DN, Sonnenburg JL. 2010. Specificity of polysaccharide use in intestinal Bacteroides species determines diet-induced microbiota alterations. Cell. 141:1241–1252.
   PubMed Web of Science ®Google Scholar
• Stephanson CJ, Stephanson AM, Flanagan GP. 2003. Evaluation of hydroxyl radical-scavenging abilities of silica hydride, an antioxidant compound, by a Fe2+-EDTA-induced 2-hydroxyterephthalate fluorometric analysis. EUPRINT, Heverlee, Belgium. J Med Food. 6:249–253.
   PubMedGoogle Scholar
• Struyf T, Chandia NP, De Borggraeve W, Dehaen W, Geuns JMC. 2008. Preparation of pure standards of steviol glycosides. Identification of steviol glycosides by LC-MS and NMR. In: Geuns JMC. editors. Proceedings of the EUSTAS Stevia Symposium 27 June 2008, KU Leuven, Belgium. 29–44. ISBN: D/2008/6045/50.
   Google Scholar
• Tarini J, Wolever TM. 2010. The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects. Appl Phys Nut Metab. 35:9–16.
   PubMed Web of Science ®Google Scholar
• Van den Ende W. 1996. Fructan metabolism in chicory roots (Cichorium intybus L.), PhD dissertation, KU Leuven, Belgium, 180 pp.
   Google Scholar
• Van den Ende W, Valluru R. 2009. Sucrose, sucrosyl oligosaccharides, and oxidative stress: Scavenging and salvaging?. J Exp Bot. 60:9–18.
   PubMed Web of Science ®Google Scholar
• Van den Ende W, Van Laere A. 2007. Fructans in dicotyledonous plants: Occurrence and metabolism. In: Shiomi N, Benkeblia N, Onodera S. editors. Recent Advances in Fructooligosaccharides Research. 1–14 Research Signpost, Kerala, India. ISBN: 81-308-0146-9.
   Google Scholar
• Vereyken IJ, van Kuik JA, Evers TH, Rijken PJ, de Kruijff B. 2003. Structural requirements of the fructan-lipid interaction. Biophys J. 84:3147–3154.
   PubMed Web of Science ®Google Scholar
• Villegas B, Tarrega A, Carbonell I, Costell E. 2010. Optimising acceptability of new prebiotic low-fat milk beverages. Food Qual Prefer. 21:234–242.
   Web of Science ®Google Scholar
• Welters CFM, Heineman E, Thunissen FBJM, van den Bogaard AEJM, Soeters PB, Baeten CGMI. 2002. Effect of dietary inulin supplementation on inflammation of pouch mucosa in patients with an ileal puch-anal anastomosis. Dis Colon Rectum. 45:621–627.
   PubMed Web of Science ®Google Scholar
• Yuan F, Yu R, Yin Y, Shen J, Dong Q, Zhong L. 2010. Structure characterization and antioxidant activity of a novel polysaccharide isolated from Ginkgo biloba. Int J Biol Macromol. 46:436–439.
   PubMed Web of Science ®Google Scholar
• Yun H, Lee JH, Park CE, Kim MJ, Min B-I, Bae H, Choe W, Kang I, Kim S-S, Ha J. 2009. Inulin increases glucose transport in C2C12 myotubes and HepG2 cells via activation of AMP-activated protein kinase and phosphatidylinositol 3-kinase pathways. J Med Food. 12:1023–1028.
   PubMed Web of Science ®Google Scholar