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In Vitro and Animal Studies

Identification of ACE-inhibitory peptides from Phaseolus vulgaris after in vitro gastrointestinal digestion

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Pages 774-782 | Received 15 May 2015, Accepted 12 Aug 2015, Published online: 23 Sep 2015

References

  • Acharya KR, Sturrock ED, Riordan JF, Ehlers MRW. 2003. ACE revisited: a new target for structure-based drug design. Nat Rev 2:891–902
  • Adler-Nissen J. 1979. Determination of the degree of hydrolysis of food protein hydrolysates by trinitrobenzenesulfonic acid. J Agric Food Chem 27:1256–1262
  • Bazzano LA, He J, Ogden LG, Loria C, Vupputuri S, Myers L, Whelton PK. 2001. Legume consumption and risk of coronary heart disease in US men and women. NHANES I epidemiologic follow-up study. Arch Int Med 161:2573–2578
  • Betancur-Ancona D, Sosa-Espinoza T, Ruiz-Ruiz J, Segura-Campos M, Chel-Guerrero L. 2014. Enzymatic hydrolysis of hard-to-cook bean (Phaseolus vulgaris L.) protein concentrates and its effect on biological and functional properties. Int J Food Sci Tech 49:2–8
  • Boschin G, Scigliuolo GM, Resta D, Arnoldi A. 2014. ACE-inhibitory activity of enzymatic protein hydrolysates from lupin and other legumes. Food Chem 145:34–40
  • Byun HG, Kim SK. 2002. Structure and activity of angiotensin I converting enzyme inhibitory peptides derived from Alaskan pollack skin – enzyme peptides from pollack. J Biochem Mol Biol 35:239–243
  • Carrasco-Castilla J, Hernández-Álvarez AJ, Jiménez-Martínez C, Jacinto-Hernández C, Alaiz M, Girón-Calle J, Vioque J, Dávila-Ortiz G. 2012. Antioxidant and metal chelating activities of Phaseolus vulgaris L. var. Jamapa protein isolates, phaseolin and lectin hydrolysates. Food Chem 131:1157–1164
  • Chen HM, Muramoto K, Yamauchi F, Nokihara K. 1996. Antioxidant activity of designed peptides based on the antioxidant peptide isolated from digests of a soybean protein. J Agric Food Chem, 44:2619–2623
  • Cheung HS, Wang FL, Ondetti MA, Sabo EF, Cushman DW. 1980. Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J. Biol Chem 255:401–407
  • Dei Più L, Tassoni A, Serrazanetti DI, Ferri M, Babini E, Tagliazucchi D, Gianotti A. 2014. Exploitation of starch industry liquid by-product to produce bioactive peptides from rice hydrolyzed proteins. Food Chem 155:199–206
  • Fujita H, Yokoyama K, Yoshikawa M. 2000. Classification of antihypertensive activity of angiotensin I-converting enzyme inhibitory peptides derived from food proteins. J Food Sci 65:564–569
  • García MC, Puchalska P, Esteve C, Marina ML. 2013. Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. Talanta 106:328–349
  • Hernández-Ledesma B, Quiros A, Amigo L, Recio I. 2007. Identification of bioactive peptides after digestion of human milk and infant formula with pepsin and pancreatin. Int Dairy J 17:42–49
  • Jivotovskaya AV, Senyuk VI, Rotari VI, Horstamann C, Vaintraub IA. 1996. Proteolysis of phaseolin in relation to its structure. J Agric Food Chem 44:3768–3772
  • Kopf-Bolanz KA, Schwander F, Gijs M, Vergères G, Portmann R, Egger L. 2012. Validation of an in vitro digestive system for studying macronutrient decomposition in humans. J Nutr 142:245–250
  • Li H, Aluko RE. 2010. Identification and inhibitory properties of multifunctional peptides from pea protein hydrolysate. J Agric Food Chem 58:11471–11476
  • Luna-Vital DA, Mojica L, González de Mejía E, Mendoza S, Loarca-Piña G. 2015. Biological potential of protein hydrolysates and peptides from common bean (Phaseolus vulgaris L.): a review. Food Res Int 76:39–50
  • Mandalari G, Bisignano G, Wickham M. 2011. Food matrix and processing affect almond protein release during simulated digestion. Clin Transl Allergy 1:P20. doi:10.1186/2045-7022-1-S 1-P20
  • Meisel H. 1998. Overview on milk protein-derived peptides. Int Dairy J 8:363–373
  • Meisel H, Walsh DJ, Murray B, FitzGerald RJ. 2006. ACE inhibitory peptides. In: Mine Y, Shahidi F, editors. Nutraceutical proteins and peptides in health and disease. New York: CRC Taylor & Francis Group. p 269–315
  • Mojica L, Chen K, de Mejia EG. 2015. Impact of commercial precooking of common bean (Phaseolus vulgaris) on the generation of peptides, after pepsin-pancreatin hydrolysis, capable to inhibit dipeptidyl peptidase-IV. J Food Sci 80:H188–H198
  • Montoya CA, Leterme P, Victoria NF, Toro O, Souffrant WB, Beebe S, Lallès JP. 2008. Susceptibility of phaseolin to in vitro proteolysis is highly variable across common bean varieties (Phaseolus vulgaris). J Agric Food Chem 56:2183–2191
  • Motoi H, Kodama T. 2003. Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides from wheat gliadin hydrolysate. Nahrung 47:354–358
  • Nakahara T, Sano A, Yamaguchi H, Sugimoto K, Chikata H, Kinoshita E, Uchida R. 2010. Antihypertensive effect of peptide-enriched soy sauce-like seasoning and identification of its angiotensin I-converting enzyme inhibitory substances. J Agric Food Chem 58:821–827
  • Nongonierma AB, Mooney C, Shields DC, FitzGerald RJ. 2013. Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides. Food Chem 141:644–653
  • Phelan M, Kerins D. 2011. The potential role of milk-derived peptides in cardiovascular disease. Food Funct 2:153–167
  • Picariello G, Iacomino G, Mamone G, Ferranti P, Fierro O, Gianfrani C, Di Luccia A, Addeo F. 2013. Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins. Food Chem 139:203–212
  • Polovic N, Blanusa M, Gavrovic-Jankulovic M, Atanaskovic-Markovic M, Burazer L, Jankov R, Cirkovic Velickovic T. 2007. A matrix effect in pectin-rich fruits hampers digestion of allergen by pepsin in vivo and in vitro. Clin Exp Allergy 37:764–771
  • Qian ZL, Jung WK, Lee SH, Byun HG, Kim SK. 2007. Antihypertensive effect of an angiotensin I-converting enzyme inhibitory peptide from bulfrog (Rana catesbeiana Shaw) muscle protein in spontaneously hypertensive rats. Proc Biochem 42:1443–1448
  • Ronca-Testoni S. 1983. Direct spectrophotometric assay for angiotensin-converting enzyme in serum. Clin Chem 29:1093–1096
  • Rui X, Boye JI, Barbana C, Simpson BK, Prasher SO. 2012a. Electrophoretic profiles and angiotensin I-converting enzyme inhibitory activities of nine varieties of Phaseolus Vulgaris protein hydrolysates. J Nutr Food Sci 2:156. doi:10.4172/2155-9600.1000156
  • Rui X, Boye JI, Simpson BK, Prasher SO. 2012b. Angiotensin I-converting enzyme inhibitory properties of Phaseolus vulgaris bean hydrolysates: effects of different thermal and enzymatic digestion treatments. Food Res Int 49:739–746
  • Rui X, Boye JI, Simpson BK, Prasher SO. 2013. Purification and characterization of angiotensin I-converting enzyme inhibitory peptides of small red bean (Phaseolus vulgaris) hydrolysates. J Funct Foods 5:1116–1124
  • Stuknite M, Cattaneo S, Pagani MA, Marti A, Micard V, Hogenboom J, De Noni I. 2014. Spaghetti from durum wheat: effect of drying conditions on heat damage, ultrastructure and in vitro digestibility. Food Chem 149:40–46
  • Tagliazucchi D, Verzelloni E, Conte A. 2005. Effect of some phenolic compounds and beverages on pepsin activity during simulated gastric digestion. J Agric Food Chem 53:8706–8713
  • Torruco-Uco J, Chel-Guerrero L, Martınez-Ayala A, Davila-Ortız G, Betancur-Ancona D. 2009. Angiotensin-I converting enzyme inhibitory and antioxidant activities of protein hydrolysates from Phaseolus lunatus and Phaseolus vulgaris seeds. LWT-Food Sci Tech 42:1597–1604
  • van Platerink CJ, Janssen HGM, Haverkamp J. 2008. Application of at-line two-dimensional liquid chromatography-mass spectrometry for identification of small hydrophilic angiotensin I-inhibiting peptides in milk hydrolysates. Anal Bioanal Chem 391:299–307
  • Valdez-Ortiz A, Fuentes-Gutíerrez CI, Germán-Báez LJ, Gutiérrez-Dorado R, Medina-Godoy S. 2012. Protein hydrolysates obtained from Azufrado (sulphur yellow) beans (Phaseolus vulgaris): Nutritional, ACE-inhibitory and antioxidative characterization. LWT-Food Sci Tech 46:91–96
  • Vermeirssen V, Van Camp J, Verstraete W. 2004. Bioavailability of angiotensin I converting enzyme inhibitory peptides. Br J Nutr 92:357–366
  • Vermeirssen V, Van Camp J, Verstraete W. 2005. Fractionation of angiotensin I converting enzyme inhibitory activity from pea and whey protein in vitro gastro-intestinal digests. J Sci Food Agric 85:399–405
  • Wu J, Aluko RE, Nakai S. 2006. Structural requirements of angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tri-peptides. J Agric Food Chem 54:732–738
  • Wu H, He HL, Chen XL, Sun CY, Zhang YZ, Zhou BC. 2008. Purification and identification of novel angiotensin I-converting enzyme inhibitory peptides from shark meat hydrolysate. Proc Biochem 4:457–461

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