Grape seed proanthocyanidin extracts prevent hyperglycemia-induced monocyte adhesion to aortic endothelial cells and ameliorates vascular inflammation in high-carbohydrate/high-fat diet and streptozotocin-induced diabetic rats

References

• Bakker W, Eringa EC, Sipkema P, van Hinsbergh VW. 2009. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 335:165–189.
   PubMed Web of Science ®Google Scholar
• Basta G, Lazzerini G, Massaro M, Simoncini T, Tanganelli P, Fu C, Kislinger T, Stern DM, Schmidt AM, De Caterina R. 2002. Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses. Circulation. 105:816–822.
   PubMed Web of Science ®Google Scholar
• Beckman JA, Creager MA, Libby P. 2002. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 287:2570–2581.
   PubMed Web of Science ®Google Scholar
• Chavakis T, Bierhaus A, Nawroth PP. 2004. RAGE (receptor for advanced glycation end products): a central player in the inflammatory response. Microbes Infect. 6:1219–1225.
   PubMed Web of Science ®Google Scholar
• Chira K, Schmauch G, Saucier C, Fabre S, Teissedre PL. 2009. Grape variety effect on proanthocyanidin composition and sensory perception of skin and seed tannin extracts from bordeaux wine grapes (Cabernet Sauvignon and Merlot) for two consecutive vintages (2006 and 2007). J Agric Food Chem. 57:545–553.
   PubMed Web of Science ®Google Scholar
• Cui XP, Li BY, Gao HQ, Wei N, Wang WL, Lu M. 2008. Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats. J Nutr Sci Vitaminol (Tokyo). 54:321–328.
   PubMed Web of Science ®Google Scholar
• DeGraba TJ. 1997. Expression of inflammatory mediators and adhesion molecules in human atherosclerotic plaque. Neurology. 49:S15–S19.
   PubMed Web of Science ®Google Scholar
• Di Minno MN, Iervolino S, Peluso R, Scarpa R, Di Minno G, CaRRDs Study Group. 2011. Carotid intima-media thickness in psoriatic arthritis: differences between tumor necrosis factor-α blockers and traditional disease-modifying antirheumatic drugs. Arterioscler Thromb Vasc Biol. 31:705–712.
   PubMed Web of Science ®Google Scholar
• Duperray A, Mantovani A, Introna M, Dejana E. 1995. Endothelial cell regulation of leukocyte infiltration in inflammatory tissues. Mediators Inflamm. 4:322–330.
   PubMed Web of Science ®Google Scholar
• Hatley ME, Srinivasan S, Reilly KB, Bolick DT, Hedrick CC. 2003. Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. J Biol Chem. 278:25369–25375.
   PubMed Web of Science ®Google Scholar
• Kawano N, Emoto M, Mori K, Yamazaki Y, Urata H, Tsuchikura S, Motoyama K, Morioka T, Fukumoto S, Shoji T, et al. 2012. Association of endothelial and vascular smooth muscle dysfunction with cardiovascular risk factors, vascular complications, and subclinical carotid atherosclerosis in type 2 diabetic patients. J Atheroscler Thromb. 19:276–284.
   PubMed Web of Science ®Google Scholar
• Kodama M, Yamasaki Y, Sakamoto K, Yoshioka R, Matsuhisa M, Kajimoto Y, Kosugi K, Ueda N, Hori M. 2000. Antiplatelet drugs attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. Thromb Res. 97:239–245.
   PubMed Web of Science ®Google Scholar
• Kopp CW, Hölzenbein T, Steiner S, Marculescu R, Bergmeister H, Seidinger D, Mosberger I, Kaun C, Cejna M, Horvat R, et al. 2004. Inhibition of restenosis by tissue factor pathway inhibitor: in vivo and in vitro evidence for suppressed monocyte chemoattraction and reduced gelatinolytic activity. Blood. 103:1653–1661.
   PubMed Web of Science ®Google Scholar
• Li BY, Cheng M, Gao HQ, Ma YB, Xu L, Li XH, Li XL, You BA. 2008. Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy. J Cell Biochem. 104:668–679.
   PubMed Web of Science ®Google Scholar
• Li XL, Li BY, Gao HQ, Cheng M, Xu L, Li XH, Ma YB. 2009. Effects of grape seed proanthocyanidin extracts on aortic pulse wave velocity in streptozocin induced diabetic rats. Biosci Biotechnol Biochem. 73:1348–1354.
   PubMed Web of Science ®Google Scholar
• Ma L, Gao HQ, Li BY, Ma YB, You BA, Zhang FL. 2007. Grape seed proanthocyanidin extracts inhibit vascular cell adhesion molecule expression induced by advanced glycation end products through activation of peroxisome proliferators-activated receptor gamma. J Cardiovasc Pharmacol. 49:293–298.
   PubMed Web of Science ®Google Scholar
• Méndez JD, Xie J, Aguilar-Hernandez M, Méndez-Valenzuela V. 2010. Trends in advanced glycation end products research in diabetes mellitus and its complications. Mol Cell Biochem. 341:33–41.
   PubMed Web of Science ®Google Scholar
• Poirier P, Eckel RH. 2000. Advanced glycation end products and coronary heart disease in type 2 diabetes. Diabetes Care. 23:1441–1442.
   PubMed Web of Science ®Google Scholar
• Potenza MA, Gagliardi S, Nacci C, Carratu MR, Montagnani M. 2009. Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets. Curr Med Chem. 16:94–112.
   PubMed Web of Science ®Google Scholar
• Ramasamy R, Yan SF, Herold K, Clynes R, Schmidt AM. 2008. Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis. Ann N Y Acad Sci. 1126:7–13.
   PubMed Web of Science ®Google Scholar
• Rose LM, Petersen R, Mehra R, Alvord EC. 1988. Endothelial cell Ia increases before inflammatory cell infiltration in EAE induced in long-tailed macaques. Ann N Y Acad Sci. 540:315–318.
   PubMedGoogle Scholar
• Shi W, Wang NJ, Shih DM, Sun VZ, Wang X, Lusis AJ. 2000. Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism. Circ Res. 86:1078–1084.
   PubMed Web of Science ®Google Scholar
• Soro-Paavonen A, Forbes JM. 2006. Novel therapeutics for diabetic micro- and macrovascular complications. Curr Med Chem. 13:1777–1788.
   PubMed Web of Science ®Google Scholar
• Srinivasan S, Bolick DT, Hatley ME, Natarajan R, Reilly KB, Yeh M, Chrestensen C, Sturgill TW, Hedrick CC. 2004. Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes. J Biol Chem. 279:31930–31936.
   PubMed Web of Science ®Google Scholar
• Strojek K. 2003. Features of macrovascular complications in type 2 diabetic patients. Acta Diabetol. 40:S334–S337.
   PubMed Web of Science ®Google Scholar
• Tan KC, Chow WS, Ai VH, Metz C, Bucala R, Lam KS. 2002. Advanced glycation end products and endothelial dysfunction in type 2 diabetes. Diabetes Care. 25:1055–1059.
   PubMed Web of Science ®Google Scholar
• Xu L, Li B, Cheng M, Zhang W, Pan J, Zhang C, Gao H. 2008. Oral administration of grape seed proanthocyanidin extracts downregulate RAGE dependant nuclear factor-kappa BP65 expression in the hippocampus of streptozotocin induced diabetic rats. Exp Clin Endocrinol Diabetes. 116:215–224.
   PubMed Web of Science ®Google Scholar
• Yamagishi S, Maeda S, Matsui T, Ueda S, Fukami K, Okuda S. 2012. Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes. Biochim Biophys Acta. 1820:663–671.
   PubMed Web of Science ®Google Scholar
• Yang H, Xu Z, Liu W, Wei Y, Deng Y, Xu B. 2012. Effect of grape seed proanthocyanidin extracts on methylmercury-induced neurotoxicity in rats. Biol Trace Elem Res. 147:156–164.
   PubMed Web of Science ®Google Scholar
• Zhang FL, Gao HQ, Wu JM, Ma YB, You BA, Li BY, Xuan JH. 2006. Selective inhibition by grape seed proanthocyanidin extracts of cell adhesion molecule expression induced by advanced glycation end products in endothelial cells. J Cardiovasc Pharmacol. 48:47–53.
   PubMed Web of Science ®Google Scholar