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Research Article

Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34

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Pages 23-30 | Received 14 Jun 2009, Published online: 06 Dec 2009

References

  • Mellman I. 1996. Endocytosis and molecular sorting. Annu Rev Cell Dev Biol 12:575–625.
  • Gruenberg J. 2001. The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2:721–730.
  • Polo S, Di Fiore PP. 2006. Endocytosis conducts the cell signaling orchestra. Cell 124:897–900.
  • Raposo G, Fevrier B, Stoorvogel W, Marks MS. 2002. Lysosome-related organelles: A view from immunity and pigmentation. Cell Struct Funct 27:443–456.
  • Germain DP. 2002. Lysosomes and lysosomal storage diseases. J Soc Biol 196:127–134.
  • Shiflett SL, Kaplan J, Ward DM. 2002. Chediak-Higashi Syndrome: A rare disorder of lysosomes and lysosome related organelles. Pigment Cell Res 15:251–257.
  • Hirota Y, Kuronita T, Fujita H, Tanaka Y. 2007. A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments. Biochem Biophys Res Commun 364:40–47.
  • Bucci C, Thomsen P, Nicoziani P, McCarthy J, van Deurs B. 2000. Rab7: A key to lysosome biogenesis. Mol Biol Cell 11:467–480.
  • Cantalupo G, Alifano P, Roberti V, Bruni CB, Bucci C. 2001. Rab-interacting lysosomal protein (RILP): The Rab7 effector required for transport to lysosomes. Embo J 20:683–693.
  • Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, Janssen H, Wubbolts R, Neefjes J. 2001. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr Biol 11:1680–1685.
  • Wang T, Hong W. 2002. Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein. Mol Biol Cell 13:4317–4332.
  • Wang T, Wong KK, Hong W. 2004. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol Biol Cell 15:815–826.
  • Caplan S, Hartnell LM, Aguilar RC, Naslavsky N, Bonifacino JS. 2001. Human Vam6p promotes lysosome clustering and fusion in vivo. J Cell Biol 154:109–122.
  • Olkkonen VM, Stenmark H. 1997. Role of Rab GTPases in membrane traffic. Int Rev Cytol 176:1–85.
  • Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W. 2004. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. Mol Biol Cell 15:4011–4022.
  • Mori T, Fukuda Y, Kuroda H, Matsumura T, Ota S, Sugimoto T, Nakamura Y, Inazawa J. 1999. Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors. Biochem Biophys Res Commun 254:594–600.
  • Nakamura N, Hirata A, Ohsumi Y, Wada Y. 1997. Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae. J Biol Chem 272:11344–11349.
  • Wurmser AE, Sato TK, Emr SD. 2000. New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol 151:551–562.
  • Seabra MC, Mules EH, Hume AN. 2002. Rab GTPases, intracellular traffic and disease. Trends Mol Med 8:23–30.
  • Corbeel L, Freson K. 2008. Rab proteins and Rab-associated proteins: Major actors in the mechanism of protein-trafficking disorders. Eur J Pediatr 167:723–729.
  • Zhang M, Chen L, Wang S, Wang T. 2009. Rab7: Roles in membrane trafficking and disease. Biosci Rep 29:193–209.
  • Spinosa MR, Progida C, De Luca A, Colucci AM, Alifano P, Bucci C. 2008. Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease. J Neurosci 28:1640–1648.
  • Menasche G, Pastural E, Feldmann J, Certain S, Ersoy F, Dupuis S, Wulffraat N, Bianchi D, Fischer A, Le Deist F, de Saint Basile G. 2000. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet 25:173–176.
  • Cheng KW, Lahad JP, Kuo WL, Lapuk A, Yamada K, Auersperg N, Liu J, Smith-McCune K, Lu KH, Fishman D, Gray JW, Mills GB. 2004. The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nat Med 10:1251–1256.
  • Lackner MR, Kindt RM, Carroll PM, Brown K, Cancilla MR, Chen C, de Silva H, Franke Y, Guan B, Heuer T, Hung T, Keegan K, Lee JM, Manne V, O'Brien C, Parry D, Perez-Villar JJ, Reddy RK, Xiao H, Zhan H, Cockett M, Plowman G, Fitzgerald K, Costa M, Ross-Macdonald P. 2005. Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors. Cancer Cell 7:325–336.
  • Zhou J, Fogelgren B, Wang Z, Roe BA, Biegel JA. 2000. Isolation of genes from the rhabdoid tumor deletion region in chromosome band 22q11.2. Gene 241:133–141.
  • Marks MS, Seabra MC. 2001. The melanosome: Membrane dynamics in black and white. Nat Rev Mol Cell Biol 2:738–748.
  • Kaplan J, De Domenico I, Ward DM. 2008. Chediak-Higashi syndrome. Curr Opin Hematol 15:22–29.

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