834
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Analysis of a promoter polymorphism of the GLUT1 gene in patients with hepatocellular carcinoma

, , &
Pages 182-186 | Received 09 Aug 2010, Accepted 05 Nov 2010, Published online: 18 Feb 2011

References

  • Amann T, Hellerbrand C. 2009. GLUT1 as a therapeutic target in hepatocellular carcinoma. Expert Opin Ther Targets 13(12):1411–1427.
  • Amann T, Maegdefrau U, Hartmann A, Agaimy A, Marienhagen J, Weiss TS, Stoeltzing O, Warnecke C, Scholmerich J, Oefner PJ, Kreutz M, Bosserhoff AK, Hellerbrand C. 2009. GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis. Am J Pathol 174(4):1544–1552.
  • Brahimi-Horn MC, Chiche J, Pouyssegur J. 2007. Hypoxia signalling controls metabolic demand. Curr Opin Cell Biol 19(2):223–229.
  • Bruix J, Boix L, Sala M, Llovet JM. 2004. Focus on hepatocellular carcinoma. Cancer Cell 5(3):215–219.
  • Cooper R, Sarioglu S, Sokmen S, Fuzun M, Kupelioglu A, Valentine H, Gorken IB, Airley R, West C. 2003. Glucose transporter-1 (GLUT-1): A potential marker of prognosis in rectal carcinoma? Br J Cancer 89(5):870–876.
  • Farazi PA, DePinho RA. 2006. Hepatocellular carcinoma pathogenesis: From genes to environment. Nat Rev Cancer 6(9):674–687.
  • Hellerbrand C, Amann T, Schlegel J, Wild P, Bataille F, Spruss T, Hartmann A, Bosserhoff AK. 2008. The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma. Gut 57(2):243–251.
  • Hodgkinson AD, Page T, Millward BA, Demaine AG. 2005. A novel polymorphism in the 5′ flanking region of the glucose transporter (GLUT1) gene is strongly associated with diabetic nephropathy in patients with Type 1 diabetes mellitus. J Diabetes Complic 19(2):65–69a.
  • Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. 2008. Cancer statistics, 2008. CA Cancer J Clin 58(2):71–96.
  • Kim JW, Dang CV. 2006. Cancer's molecular sweet tooth and the Warburg effect. Cancer Res 66(18):8927–8930.
  • Muhlbauer M, Bosserhoff AK, Hartmann A, Thasler WE, Weiss TS, Herfarth H, Lock G, Scholmerich J, Hellerbrand C. 2003. A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease. Gastroenterology 125(4):1085–1093.
  • Oliver RJ, Woodwards RT, Sloan P, Thakker NS, Stratford IJ, Airley RE. 2004. Prognostic value of facilitative glucose transporter Glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC Translational Research Fund studies. Eur J Cancer 40(4):503–507.
  • Page T, Hodgkinson AD, Ollerenshaw M, Hammonds JC, Demaine AG. 2005. Glucose transporter polymorphisms are associated with clear-cell renal carcinoma. Cancer Genet Cytogenet 163(2):151–155.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.