Cholesterol modulates the interaction of the islet amyloid polypeptide with membranes

References

• Akesson B, Panagiotidis G, Westermark P, Lundquist I. 2003. Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets. Regul Pept 111:55–60
   Google Scholar
• Anguiano M, Nowak RJ, Lansbury PT Jr. 2002. Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes. Biochemistry 41:11338–11343
   PubMedGoogle Scholar
• Bartolini M, Bertucci C, Bolognesi ML, Cavalli A, Melchiorre C, Andrisano V. 2007. Insight into the kinetic of amyloid beta (1–42) peptide self-aggregation: Elucidation of inhibitors’ mechanism of action. ChemBioChem 8:2152–2161
   PubMed Web of Science ®Google Scholar
• Brender JR, Salamekh S, Ramamoorthy A. 2012. Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective. Acc Chem Res 45:454–462
   Google Scholar
• Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, et al. 2007. beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nature Med 13:340–347
   PubMed Web of Science ®Google Scholar
• Caillon L, Lequin O, Khemtémourian L. 2013. Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation. Biochim Biophys Acta 1828:2091–2098
   Google Scholar
• Cao P, Marek P, Noor H, Patsalo V, Tu LH, Wang H, et al. 2013a. Islet amyloid: From fundamental biophysics to mechanisms of cytoxicity. FEBS Lett 587:1106–1118
   PubMedGoogle Scholar
• Cao P, Abedini A, Raleigh DP. 2013b. Aggregation of islet amyloid polypeptide: From physical chemistry to cell biology. Curr Opin Struct Biol 23:82–89
   Google Scholar
• Cao P, Abedini A, Wang H, Tu LH, Zhang X, Schmidt AM, Raleigh DP. 2013c. Islet amyloid polypeptide toxicity and membrane interactions. Proc Nat Acad Sci USA 110:19279–19284
   PubMed Web of Science ®Google Scholar
• Chiti F, Dobson CM. 2006. Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 75:333–366
   PubMed Web of Science ®Google Scholar
• Cho WJ, Jena BP, Jeremic AM. 2008. Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus. Methods Cell Biol 90:267–286
   Google Scholar
• Cho WJ, Trikha S, Jeremic AM. 2009. Cholesterol regulates assembly of human islet amyloid polypeptide on model membranes. J Mol Biol 393:765–775
   Google Scholar
• Clark A, Wells CA, Buley ID, Cruickshank JK, Vanhegan RI, Matthews DR, et al. 1988. Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: Quantitative changes in the pancreas in type 2 diabetes. Diabetes Res 9:151–159
   PubMedGoogle Scholar
• Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB. 1987. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA 84:8628–8632
   PubMed Web of Science ®Google Scholar
• Dante S, Hauss T, Dencher NA. 2006. Cholesterol inhibits the insertion of the Alzheimer’s peptide Aβ(25-35) in lipid bilayer. Eur Biophys J 35:523–531
   PubMed Web of Science ®Google Scholar
• Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG. 2005. Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280:17294–17300
   PubMed Web of Science ®Google Scholar
• Engel MFM, Khemtémourian L, Kleijer CC, Meeldijk HJ, Jacobs J, Verkleij AJ, et al. 2008. Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane. Proc Natl Acad Sci USA 105:6033–6038
   PubMedGoogle Scholar
• Friedman R, Pellarin R, Caflisch A. 2009. Amyloid aggregation on lipid bilayers and its impact on membrane permeability. J Mol Biol 387:407–415
   Google Scholar
• Hao M, Bogan JS. 2009. Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate. J Biol Chem 284:29489–29498
   Google Scholar
• Hasper HE, Kramer NE, Smith JL, Hillman JD, Zachariah C, Kuipers OP, et al. 2006. An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science 313:1636–1637
   PubMed Web of Science ®Google Scholar
• Jan A, Adolfsson O, Allaman I, Buccarello AL, Magistretti PJ, Pfeifer A, et al. 2011. Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species. J Biol Chem 286:8585–8596
   Google Scholar
• Jayasinghe SA, Langen R. 2005. Lipid membranes modulate the structure of islet amyloid polypeptide. Biochemistry 44:12113–12119
   PubMedGoogle Scholar
• Ji SR, Wu JY, Sui SF. 2002. Cholesterol is an important factor affecting the memrbane insertion of β-amyloid peptide (Aβ1-40), which may potentially inhibit the fibril formation. J Biol Chem 277:6273–6279
   PubMedGoogle Scholar
• Kahn SE, D’Alessio DA, Schwartz MW, Fujimoto WY, Ensinck JW, Taborsky GJ Jr, Porte D Jr. 1990. Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes 39:634–638
   PubMed Web of Science ®Google Scholar
• Karlsson E. 1999. IAPP as a regulator of glucose homeostasis and pancreatic hormone secretion (review). Int J Mol Med 3:577–584
   PubMed Web of Science ®Google Scholar
• Khemtémourian L, Lahoz Casarramona G, Syulen DPL, Hackeng TM, Meeldijk JD, De Kruijff B, et al. 2009. Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane in vitro. Biochemistry 48:10918–10925
   Google Scholar
• Khemtémourian L, Domenech E, Doux JPF, Koorengevel MC, Killian JA. 2011. Low pH acts as inhibitor of membrane damage induced by human islet amyloid polypeptide. J Am Chem Soc 133:15598–15604
   PubMed Web of Science ®Google Scholar
• Khemtémourian L, Killian JA, Höppener JWM, Engel MFM. 2008. Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus. Exp Diabetes Res 2008:421287
   PubMed Web of Science ®Google Scholar
• Knight JD, Miranker AD. 2004. Phospholipid catalysis of diabetic amyloid assembly. J Mol Biol 341:1175–1187
   PubMed Web of Science ®Google Scholar
• Knight JD, Hebda JA, Miranker AD. 2006. Conserved and cooperative assembly of membrane-bound α-helical states of islet amyloid polypeptide. Biochemistry 45:9496–9508
   PubMedGoogle Scholar
• Konarkowska B, Aitken JF, Kistler J, Zhang S, Cooper GJ. 2006. The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells. FEBS J 273:3614–3624
   Google Scholar
• Lau TL, Gehman JD, Wade JD, Masters CL, Barnham KJ, Separovic F. 2007. Cholesterol and Clioquinol modulation of Aβ(1-42) interaction with phospholipid bilayers and metals. Biochim Biophys Acta 1768:3135–3144
   Google Scholar
• Liu M, Mao X, Ye C, Huang H, Nicholson JK, Lindon JC. 1998. Improved WATERGATE pulse sequences for solvent suppression in NMR spectroscopy. J Magn Reson 132:125–129
   Web of Science ®Google Scholar
• Lorenzo A, Razzaboni B, Weir GC, Yankner BA. 1994. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature 368:756–760
   PubMed Web of Science ®Google Scholar
• Lukinius A, Wilander E, Westermark GT, Engstrom U, Westermark P. 1989. Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets. Diabetologia 32:240–244
   PubMed Web of Science ®Google Scholar
• Mirzabekov TA, Lin MC, Kagan BL. 1996. Pore formation by the cytotoxic islet amyloid peptide amylin. J Biol Chem 271:1988–1992
   PubMed Web of Science ®Google Scholar
• Potter KJ, Abedini A, Marek P, Klimek AM, Butterworth S, Driscoll M, et al. 2010. Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts. Proc Natl Acad Sci USA 107:4305–4310
   PubMed Web of Science ®Google Scholar
• Reda TK, Geliebter A, Pi-Sunyer FX. 2002. Amylin, food intake, and obesity. Obes Res 10:1087–1091
   PubMedGoogle Scholar
• Rouser G, Fkeischer S, Yamamoto A. 1970. Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids 5:494–496
   PubMed Web of Science ®Google Scholar
• Rushing PA, Hagan MM, Seeley RJ, Lutz TA, D’Alessio DA, Air EL, Woods SC. 2001. Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinology 142:5035
   PubMedGoogle Scholar
• Sani MA, Gehman JD, Separovic F. 2011. Lipid matrix plays a role in Abeta fibril kinetics and morphology. FEBS Lett 585:749–754
   Google Scholar
• Sciacca MFM, Brender JR, Lee DK, Ramamoorthy A. 2012. Phosphatidylethanolamine enhaces amyloid fiber-dependent membrane fragmentation. Biochemistry 51:7676–7684
   Google Scholar
• Seeliger J, Weise K, Opitz N, Winter R. 2012. The effect of abeta on IAPP aggregation in the presence of an isolated beta-cell membrane. J Mol Biol 421:348–363
   Google Scholar
• Selkoe DJ. 2003. Folding proteins in fatal ways. Nature 426:900–904
   PubMed Web of Science ®Google Scholar
• Sipe JD. 1994. Amyloidosis. Crit Rev Clin Lab Sci 31:325–354
   PubMed Web of Science ®Google Scholar
• Sparr E, Engel MFM, Sakharov DV, Sprong M, Jacobs J, de Kruijff B, et al. 2004. Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers. FEBS Lett 577:117–120
   PubMed Web of Science ®Google Scholar
• Stridsberg M, Sandler S, Wilander E. 1993. Cosecretion of islet amyloid polypeptide (IAPP) and insulin from isolated rat pancreatic islets following stimulation or inhibition of beta-cell function. Regul Pept 45:363–370
   PubMedGoogle Scholar
• Trikha S, Jeremic AM. 2011. Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol. J Biol Chem 286:36086–36097
   Google Scholar
• Wakabayashi M, Matsuzaki K. 2009. Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts. FEBS Lett 583:2854–2858
   Google Scholar
• Westermark GT, Westermark P, Berne C, Korsgren O. 2008. Widespread amyloid deposition in transplanted human pancreatic islets. N Engl J Med 359:977–979
   PubMed Web of Science ®Google Scholar
• Westermark P, Andersson A, Westermark GT. 2011. Islet amyloid polypeptide, islet amyloid, and diabetes mellitus. Physiol Rev 91:795–826
   PubMed Web of Science ®Google Scholar
• Westermark P, Wernstedt C, Wilander E, Hayden DW, O’Brien TD, Johnson KH. 1987. Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. Proc Natl Acad Sci USA 84:3881–3885
   PubMed Web of Science ®Google Scholar
• Xu W, Wei G, Su H, Nordenskiöld L, Mu Y. 2011. Effect of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: A coarse-grained molecular dynamics study. Phys Rev 84:051922
   Google Scholar