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Original Article

Protein kinase C: An example of a calcium-regulated protein binding to membranes (Review)

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Pages 65-70 | Received 12 Feb 1997, Published online: 09 Jul 2009

References

  • Bazzi M. D., Nelsestuen G. L. Association of protein kinase C with phospholipid vesicles. Biochemistry 1987; 26: 115–122
  • Bazzi M. D., Nelsestuen G. L. Protein kinase C interaction with calcium: a phospholipid-dependent process. Biochemistry 1990; 29: 7624–7630
  • Bazzi M. D., Nelsestuen G. L. Extensive segregation of acidic phospholipids in membranes induced by protein kinase C and related proteins. Biochemistry 1991a; 30: 7961–7969
  • Bazzi M. D., Nelsestuen G. L. Highly sequential binding of protein kinase C and related proteins to membranes. Biochemistry 1991b; 30: 7970–7977
  • Burn P. Amphitropic proteins: a new class of membrane proteins. Trends in Biochemical Sciences 1988; 13: 79–83
  • Carman M. G., Deems R. A., Dennis E. A. Lipid signaling enzymes and surface dilution kinetics. Journal of Biological Chemistry 1995; 270: 18711–18714
  • Coussens L., Parker P. J., Rhee L., Yang-Feng T. L., Chen E., Waterfield M. D., Francke U., Ullrich A. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science 1986; 233: 859–866
  • Davletov B. A., Südhof T. C. A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding. Journal of Biological Chemistry 1993; 268: 26386–26390
  • Epand R. M., Stafford A. R., Lester D. S. Lipid vesicles which can bind to protein kinase C and activate the enzyme in the presence of EGTA. European Journal of Biochemistry 1992; 208: 327–332
  • Essen L.-O., Perisic O., Cheung R., Katan M., Williams R. L. Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ. Nature 1996; 380: 595–602
  • Essen L.-O., Perisic O., Lynch D. E., Katan M., Williams R. L. A Ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-δ1. Biochemistry 1997; 36: 2753–2762
  • Garcia P., Gupta R., Shah S., Morris A. J., Rudge S. A., Scarlata S., Petrova V., McLaughlin S., Rebecchi M. J. The pleckstrin homology domain of phospholipase C-δ1 binds with high affinity to phosphatidylinositol 4, 5-bisphosphate in bilayer membranes. Biochemistry 1995; 34: 16228–16234
  • Grobler J. A., Essen L.-O., Williams R. L., Hurley J. H. C2 domain conformational changes in phospholipase C-δ1. Nature Structural Biology 1996; 3: 788–795
  • Hannun Y. A., Loomis C. R., Bell R. M. Activation of protein kinase C by triton X-100 mixed micells containing diacylglycero) and phosphatidylserine. Journal of Biological Chemistry 1985; 260: 10039–10043
  • Kaibuchi K., Fukumoto Y., Oku N., Takai Y., Arai K., Muramatsu M. Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C. Journal of Biological Chemistry 1989; 264: 13489–13496
  • Lauffenburger D. A., Linderman J. J. Receptors: models for binding, trafficking and signaling. Oxford University Press, New York 1993; 34–39
  • Lu Y., Nelsestuen G. L. The prothrombinase reaction: ‘mechanism switching’ between michaelis-menten and non-michaelis-menten behaviors. Biochemistry 1996; 35: 8201–8209
  • Luo J.-H., Weinstein I. B. The phorbol ester TPA markedly enhances the binding of calcium to the regulatory domain of protein kinase C β1 in the presence of phosphatidyl-serine. Journal of Biological Chemistry 1993; 268: 23580–23584
  • Luo J.-H., Khan S., O'Driscoll K., Weinstein I. B. The regulatory domain of protein kinase C β1 contains phosphatidyl-serine- and phorbol ester-dependent calcium binding activity. Journal of Biological Chemistry 1993; 268: 3715–3719
  • Luo J.-H., Xing W.-Q., Weinstein I. B. Calcium-dependent activation of protein kinase C: the role of the C2 domain in divalent cation selectivity. Carcinogenesis 1995; 16: 897–905
  • McLaughlin S. The electrostatic properties of membranes. Annual Reviews of Biophysics and Biophysical Chemistry 1989; 18: 113–136
  • Mosior M., Epand R. M. Mechanism of activation of protein kinase C: roles of diolein and phosphatidylserine. Biochemistry 1993; 32: 66–75
  • Mosior M., Epand R. M. Characterization of the calcium-binding site that regulates association of protein kinase C with phospholipid bilayers. Journal of Biological Chemistry 1994; 269: 13798–13805
  • Mosior M., Newton A. C. Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association. Journal of Biological Chemistry 1995; 270: 25526–25533
  • Mosior M., Newton A. C. Calcium-independent binding to interfacial phorbol esters causes protein kinase C to associate with membranes in the absence of acidic lipids. Biochemistry 1996; 35: 1621–1623
  • Mosior M., Golini E. S., Epand R. M. Chemical specificity and physical properties of the lipid bilayer in the regulation of protein kinase C by anionic lipids: evidence for the lack of a specific binding site for phosphatidylserine. Proceedings of the National Academy of Sciences, USA 1996; 93: 1907–1912
  • Nalefski E. A., Falke J. J. The C2 domain calcium-binding motif: structural and functional diversity. Protein Science 1996; 5: 2375–2390
  • Nalefski E. A., Sultzman L. A., Martin D. M., Kriz R. W., Towler P. S., Knopf J. L., Clark J. D. Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca2+-dependent lipid-binding domain and Ca2+-independent catalytic domain. Journal of Biological Chemistry 1994; 269: 18239–18249
  • Newton A. C. Interaction of proteins with lipid headgroups: lessons from protein kinase C. Annual Reviews of Biophysics and Biomolecular Structure 1993; 22: 1–25
  • Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1988; 334: 661–665
  • Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB Journal 1995; 9: 484–496
  • Ono Y., Fujii T., Igarashi K., Kuno T., Tanaka C., Kikkawa U., Nishizuka Y. Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence. Proceedings of the National Academy of Sciences, USA 1989; 86: 4868–4871
  • Orr J. W., Keranen L. M., Newton A. C. Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol. Journal of Biological Chemistry 1992; 267: 15263–15266
  • Parker P. J., Kour G., Marais R. M., Mitchell F., Pears C., Schaap D., Stabel S., Webster C. Protein kinase C: a family affair. Molecular and Cellular Endocrinology 1989; 65: 1–11
  • Ponting C. P., Parker P. J. Extending the C2 domain family: C2s in PKCs δ ϵ, η, Θ, phospholipases, GAPs and perforin. Protein Sciences 1996; 5: 162–153
  • Quest A. F. G., Bell R. M. The regulatory region of protein kinase Cγ: studies of phorbol ester binding to individual and combined functional segments expressed as glutathione S-transferase fusion proteins indicate a complex mechanism of regulation by phospholipids, phorbol esters and divalent cations. Journal of Biological Chemistry 1994; 169: 20000–20012
  • Rebecchi M., Peterson A., McLaughlin S. Phosphoinositide-specific phospholipase C-δ1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4, 5-bisphosphate. Biochemistry 1992; 31: 12742–12747
  • Shao X., Davletov B. A., Sutton R. B., Südhof T. C., Rizo J. Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C. Science 1996; 273: 248–251
  • Stabel S., Parker P. J. Protein kinase C. Pharmacology and Therapeutics 1991; 51: 71–95
  • Sutton R. B., Davletov B. A., Berghuis A. M., Südhof T. C., Sprang S. R. Structure of the first C2 domain of synaptotagmin I: a novel Ca2+phospholipid binding fold. Cell 1995; 80: 929–938
  • Swarjio M. A., Concha N. O., Kaetzel M. A., Dedman J. R., Seaton B. A. Ca2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V. Nature Structural Biology 1995; 2: 968–974
  • Wolf M., LeVine H., III, May W. S., Jr., Cuatrecasas P., Sahyoun N. A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters. Nature 1985; 317: 546–549
  • Zhang G., Kazanietz M. G., Blumberg P. M., Hurley J. H. Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester. Cell 1995; 81: 917–92

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