The Cardiovascular Effects of Bupropion and Nortriptyline in Depressed Outpatients

REFERENCES

• U'Prichard DC, Greenberg DA, Sheehan PP, Snyder SH: Tri-cyclic antidepressants: Therapeutic properties and affinity of a-noradrenergic receptor binding sites in the brain. Science 1978; 199:197–198
   PubMed Web of Science ®Google Scholar
• Freyschuss U, Sjovist F, Tuck D, Asberg M: Circulatory ef-fects in man of nortriptyline, a tricyclic antidepressant drug. Pharmacol Clin 1970; 2:68–71
   Google Scholar
• Glassman AH, Bigger JT Jr: Cardiovascular effects of thera-peutic doses of tricyclic antidepressants: A review. Arch Gen Psychiatry 1981; 38:815–820
   PubMed Web of Science ®Google Scholar
• Jefferson JW: Cardiovascular effects and toxicity of anx-iolytics and antidepressants. J Clin Psychiatry 1989; 50:368–378
   PubMedGoogle Scholar
• Giardina EGV, Bigger JT Jr, Glassman AH, Perel JM, Kan-tor SJ: The electrocardiographic and antiarrhythmic effects of imipramine hydrochloride at therapeutic plasma concen-trations. Circulation 1979; 60:1045–1052
   PubMed Web of Science ®Google Scholar
• Vohra J, Burrows OD, Hunt D, Sloman G: The effect of toxic and therapeutic doses of tricyclic antidepressant drugs on intracardiac conduction. Eur J Cardiol 1975; 3:219–227
   PubMedGoogle Scholar
• Glassman AH, Roose SP: Cardiovascular effects of tricyclic antidepressants. Psychiatr Ann 1987; 17:340–347
   Google Scholar
• Wenger TL, Cohn JB, Bustrack J: Comparison of the effects of bupropion and amitriptyline on cardiac conduction in de-pressed patients. J Clin Psychiatry 1983; 44(5; Sect 2):174–175
   Google Scholar
• Ferris RM, Cooper BR, Maxwell RA: Studies of bupropion's mechanism of antidepressant activity. J Clin Psychiatry 1983; 44(5; Sect 2):74–78
   Google Scholar
• Ferris RM, White HL, Cooper BR: Some neurochemical properties of a new antidepressant, bupropion hydrochloride (Wellbutrin). Drug Dev Res 1981; 1:21–35
   Web of Science ®Google Scholar
• Cooper BR, Hester TJ, Maxwell RA: Behavioral and bio-chemical effects of the antidepressant bupropion (Wellbu-trin): Evidence for selective blockade of dopamine uptake in vivo. J Pharmacol Exp Then 1980; 215:127–134
   PubMed Web of Science ®Google Scholar
• Shea VK, Wang CM: Bupropion (Wellbutrin) inhibits the fir-ing rates of noradrenergic but not serotonergic neurons. Soc Neurosci Abstr 1985; 11(1)
   Google Scholar
• Ferris RM, Cooper BR: Mechanism of antidepressant activity of bupropion. J Clin Psychiatry Monogr 1993; I1(1):2–14
   Google Scholar
• Golden RN, Rudorfer MV, Sherer MA, Linnoila M, Potter WZ: Bupropion in depressions. I. Biochemical effects and clinical response. Arch Gen Psychiatry 1988; 45:139–143
   PubMed Web of Science ®Google Scholar
• Wenger TL: The cardiovascular profile of bupropion. J Clin Psychiatry 1983; 44(5; Sect 2):176–182
   Google Scholar
• Roose SP, Dalack GW, Glassman AH, Woodring S, Walsh BT, Giardina EGV: Cardiovascular effects of bupropion in depressed patients with heart disease. Am J Psychiatry 1991; 148:512–516
   PubMed Web of Science ®Google Scholar
• Farid FF, Wenger TL, Tsai SY, Singh BN, Stern WC: Use of bupropion in patients who exhibit orthostatic hypotension on tricyclic antidepressants. J Clin Psychiatry 1983; 44(5; Sect 2):170–173
   Google Scholar
• Roose SP, Glassman AH, Giardina EGV, Johnson LL, Walsh BT, Bigger JT: Cardiovascular effects of imipramine and bupropion in depressed patients with congestive heart failure. I Clin Psychopharmacol 1987; 7:247–251
   Google Scholar
• Feighner J, Hendrickson G, Miller L, Stern W: Double-blind comparison of doxepin versus bupropion in outpatients with a major depressive disorder. J Clin Psychopharmacol 1986; 6:27–32
   PubMed Web of Science ®Google Scholar
• Richelson E. Side effects of old and new generation antide-pressants: A pharmacologic framework. J Clin Psychiatry Monogr 1991; 9:13–19
   Google Scholar
• Roose SP, Glassman AH, Giardina EG, Walsh BT, Woodring S, Bigger JT Jr: Tricyclic antidepressants in depressed pa-tients with cardiac conduction disease. Arch Gen Psychiatry 1987; 44:273–275
   PubMed Web of Science ®Google Scholar
• Giardina EGV, Barnard T, Johnson L, Sarcoff AL, Bigger IT Jr, Louie M: The antiarrhythmic effect of nortriptyline in cardiac patients with ventricular premature depolarizations. J Am Coll Cardiol 1986; 7:1363–1369
   PubMed Web of Science ®Google Scholar
• Roose SP, Glassman AH, Sins SG, Walsh BT, Bruno I1L, Wright LB: Comparison of imipramine- and nortriptyline-in-duced orthostatic hypotension: a meaningful difference. J Clin Psychopharmacol 1981; 1:316–319
   PubMed Web of Science ®Google Scholar
• Roose SP, Glassman AH, Giardiana EGV, Johnson LL, Walsh BT, Woodring S, Bigger, JT: Nortriptyline in de-pressed patients with left ventricular impairment. JAMA 1986; 256:3253–3257
   PubMed Web of Science ®Google Scholar
• Bazett HC: An analysis of the time relationship of electro-cardiograms. Heart 1920; 7:353–370
   Google Scholar
• Fridericia LS: Die systolendauer im elektrokardiogramm bei normalen menschen and bei herskranken. I. Acta Med Scand 1920; 53:469–486
   Google Scholar
• COSTART: Coding Symbols for Thesaurus of Adverse Re-action Terms, 3rd ed. Rockville, MD: U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Office of Epidemiology and Biostatistics; 1989
   Google Scholar
• Wang CM, Parker CH Jr, Maxwell RA: Electrophysiological effects of antidepressants on mammalian hearts and crayfish giant axon. J Cardiovasc Pharmacol 1981; 3:101–112
   Google Scholar
• Glassman AH, Roose SP, Bigger JT: The safety of tricyclic antidepressants in cardiac patients. JAMA 1993; 269:2673–2675
   PubMedGoogle Scholar