Centrifugal Fast Analyzers in Clinical Laboratory Analysis

References

• Whitehead A. N. Science and the Modern World. MacMillan Co., New York 1925, Lowell lectures, 1925, 32
   Google Scholar
• Anderson N. G. Analytical techniques for cell fractions. IV. Measurement and transfer of small fluid volumes. Anal. Biochem. 1968; 23: 207
   PubMed Web of Science ®Google Scholar
• Anderson N. G. Analytical techniques for cell fractions. VII. A multiple cuvette rotor for a new microanalytical system. Anal. Biochem. 1969; 28: 545
   PubMed Web of Science ®Google Scholar
• Anderson N. G. The development of automated systems for clinical and research use. Clin. Chim. Acta 1969; 25: 321
   PubMed Web of Science ®Google Scholar
• Anderson N. G. Analytical techniques for cell fractions. XIV. Use of drainage syphons in a fast-analyzer cuvette rotor. Anal. Biochem. 1969; 32: 59
   PubMed Web of Science ®Google Scholar
• Anderson N. G. Basic principles of fast analyzers. Am. J. Clin. Pathol. 1970; 52: 778
   Google Scholar
• Anderson N. G. Computer interfaced fast analyzers. Science 1969; 166: 317
   PubMed Web of Science ®Google Scholar
• Anderson N. G. The development of fast analyzers. Z. Anal. Chem. 1972; 261: 257
   Google Scholar
• Anderson N. G. The Development of Zonal Centrifuges and Ancillary Systems for Tissue Fractionation and Analysis. U.S. National Cancer Institute Monograph, 21, 1966
   Google Scholar
• Anderson N. G., Green J. G., Barber M. L., Ladd F. C., Sr. Analytical techniques for cell fractions. III. Nucleotides and related compounds. Anal. Biochem. 1963; 6: 153
   PubMed Web of Science ®Google Scholar
• Proceedings of the Third Annual Symposium on High Resolution Analyses and Advanced Concepts for the Clinical Laboratory, Oak Ridge, Tenn. Clin. Chem. 1971; 17: 685
   Web of Science ®Google Scholar
• Scott C. D., Attrill J. E., Anderson N. G. Automatic, high-resolution analysis of urine for its ultraviolet absorbing constituents. Proc. Soc. Exp. Biol. Med. 1967; 125: 181
   PubMed Web of Science ®Google Scholar
• Burtis C. A., Johnson W. F., Mailen J. C., Attrill J. E. Automated sample-reagent loader for use with the GeMSAEC fast analyzer. Clin. Chem. 1972; 18: 433
   PubMed Web of Science ®Google Scholar
• Skinner A. G., Holder R., Northam B. E., Whitehead T. P. Suitability of the Micromedic Automatic Pipette and Hamilton Precision Liquid Dispensor and automatic serum and reagent addition to the GeMSAEC fast analyzer. Scand. J. Clin. Lab. Invest. 1972; 29: 16.5
   Web of Science ®Google Scholar
• Nishi H. H. Mechanized, direct digital-control pipette for automation of ultramicro chemical analyses. Clin. Chem. 1972; 18: 771
   PubMed Web of Science ®Google Scholar
• Statland B. E., Louderback A. L. Nonlinear regression analysis approach for determining “true” lactate dehydrogenase activity in serum with the centrifugal analyzer (“Rotochem”). Clin. Chem. 1972; 18: 845
   PubMed Web of Science ®Google Scholar
• Anderson N. G., Burtis C. A., Mailen J. C., Scott C. D., Willis D. D. Feasibility of miniaturization of a fast analyzer. Anal. Lett. 1972; 5: 153
   Web of Science ®Google Scholar
• Buitis C. A., Mailen J. C., Johnson W. F., Scott C. D., Tiffany T. O., Anderson N. G. Development of a miniature fast analyzer. Clin. Chem. 1972; 18: 753
   PubMed Web of Science ®Google Scholar
• Scott C. D., Burtis C. A. Miniature fast analyzer systems. Anal. Chem. 1973; 45: 327
   Web of Science ®Google Scholar
• Burtis C. A., Johnson W. F., Mailen J. C., Overton J. B., Tiffany T. O., Watsky M. B. Development of an analytical system based around a miniature fast analyzer. Clin. Chem. 1973; 19: 895
   PubMed Web of Science ®Google Scholar
• Candler E. L., Nunley C. E., Anderson N. G. Analytical techniques for cell fractions. VI. Multiple gradient-distributor rotor (B-XXI). Anal. Biochem. 1967; 21: 253
   PubMed Web of Science ®Google Scholar
• Scott C. D., Mailen J. C. Dynamic introduction, of whole-blood samples into fast analyzers. Clin. Chem. 1972; 18: 749
   PubMed Web of Science ®Google Scholar
• Caraway W. T. Chemical and diagnostic specificity of laboratory tests - effects of hemolysis, lipemia, anticoagulants, medications, contaminants, and other variables. Am. J. Clin. Pathol. 1962; 37: 445
   PubMed Web of Science ®Google Scholar
• Fabiny D. L., Ertingshausen G. Automated reaction-rate method for determination of serum creatinine with the CentrifiChem. Clin. Chem. 1971; 17: 696
   PubMed Web of Science ®Google Scholar
• Coleman R. L. An investigation of the utility of parallel photometric analysis as a new approach for environmental determination. Ph.D. thesis, University of Tennessee, Knoxville, Tennessee 1971
   Google Scholar
• Kelley M. T., Jansen J. M. Programming concepts for the GeMSAEC rapid photometric analyzer. Clin. Chem. 1971; 17: 701
   PubMed Web of Science ®Google Scholar
• Mashburn D. N., Stevens R. H., Willis D. D., Elrod L. H., Anderson N. G. Analytical techniques for cell fractions. XVIII. The G-11C fast analyzer system. Anal. Biochem. 1970; 35: 98
   PubMed Web of Science ®Google Scholar
• Burtis C. A., Johnson W. F., Attrill J. E., Scott C. D., Cho N., Anderson N. G. Increased rate of analysis by use of a 42-cuvet GeMSAEC fast analyzer clin. Chem. 1971; 17: 686
   Web of Science ®Google Scholar
• Tiffany T. O., Burtis C. A., Mailen J. C., Thacker L. H. Dynamic multicuvette fluorometer-spectrophotometer based on the GeMSAEC fast analyzer principle. Anal. Chem. 1973; 45: 1716
   Web of Science ®Google Scholar
• Tiffany T. O., Watsky M. B., Buttis C. A., Thacker L. H. Fluorometric fast analyzer: some applications to fluorescence measurements in clinical chemistry. Clin. Chem. 1973; 19: 871
   PubMed Web of Science ®Google Scholar
• Brand L., Witholt B. Fluorescence Measurements in Methods in Enzymology, XI, C. H. W. Hirs. Academic Press, New York 1967; 776
   Google Scholar
• Udenfriend S. Fluorescence Assay in Biology and Medicine II, F. Udenfriend. Academic Press, New York 1969
   Google Scholar
• Ellis D. W. Luminescence Instrumentation and Experimental Details in Fluorescence and Phosphorescence Analysis Principles and Applications, D. M. Hercules. Interscience Publishers, New York 1966; 41
   Google Scholar
• Velapodi R. A. Considerations on organic compounds in solution and inorganic ions in glasses as fluorescent standard reference materials. J. Res. Natl. Bur. Std., A 1972; 76: 641
   Google Scholar
• Scopes F. K. Automated fluorometric analysis of biological compounds. Anal. Biochem. 1972; 49: 73
   PubMed Web of Science ®Google Scholar
• Roth M. Fluorimetric Assay of Enzymes in Methods of Biochemical Analysis, D. Click. John Wiley & Sons, New York 1969; Vol. 17
   Google Scholar
• Jacks T. J., Kircher H. Fluorometric assay for the hydrolytic activity of lipase using fatty acyl esters of 4-methylumbelliferone. Anal. Biochem. 1967; 21: 279
   PubMed Web of Science ®Google Scholar
• Guilbaut G. G. Fluorescence: Theory-Instrumentation, and Practice, G. Guilbaut. Marcel Dekker, New York 1967
   Google Scholar
• Curry R. E., Pardue H. L., Mieligg G. E., Santini R. E. Design and evaluation of a filter fluorometer which utilizes a photon-counting detector. Clin. Chem. 1973; 19: 11
   Web of Science ®Google Scholar
• Parker C. A. Raman spectra in spectrofluorimetry. Analyst 1959; 84: 446
   Web of Science ®Google Scholar
• Hatcher D. W., Anderson N. G. An optical density thermometer. Anal. Lett. 1969; 2: 373
   Web of Science ®Google Scholar
• Johnson W. F., Mailen J. C., Burtis C. A., Tiffany T. O., Scott C. D. Development of a portable data processor with mechanical data output for use with a miniature fast analyzer. Clin. Chem. 1972; 18: 762
   PubMed Web of Science ®Google Scholar
• Killingsworth L. M., Savory J. Automated immunochemical procedures for measurement of immunoglobulins IgG, IgA, and IgM inhuman serum. Clin. Chem. 1971; 17: 936
   PubMed Web of Science ®Google Scholar
• Killingsworth L. M., Savory J., Teague P. O. Automated immunoprecipitation technique for analysis of the third component of complement (C 3) in human serum. Clin. Chem 1971; 17: 374
   PubMed Web of Science ®Google Scholar
• Eckman I., Robbing J. B., Van den Hamer C. J. A., Lentz J., Scheinberg I. H. Automation of a quantitative immunochemical microanalysis of human serum transferrin: a model system. Clin. Chem. 1970; 16: 58
   PubMed Web of Science ®Google Scholar
• Killingsworth L. M., Savory J. Manual nephelometric methods for immunochemical determination of immunoglobulins IgG, IgA, and IgM in human serum. Clin. Chem. 1972; 18: 335
   PubMed Web of Science ®Google Scholar
• Larson C., Orenstein P., Ritchie R. F. An automated method for quantitation of proteins in body fluids, Technicon International Congress. Advan. Automat. Anal 1970; 1: 9
   Google Scholar
• Tengerdy R. P., Small W. H. Reaction kinetic studies of the antigen-antibody reaction. Nature 1966; 210: 708
   PubMed Web of Science ®Google Scholar
• Erskine A. G., Weiner A. S. The Principles and Practices of Blood Grouping. C. V. Mosby Company, St Louis, Mo 1973
   Google Scholar
• Race R. R., Sanger R. Blood Groups in Maned. 5. F. A. Davis, Philadelphia 1968
   Google Scholar
• Prokop O., Uhlenbruck G. Human Blood and Serum Groups. John Wiley & Sons, Inc., New York 1969, (translated by J. L. Raven)
   Google Scholar
• Anderson N. G. Basic principles of fast analyzers. presented at the First Annual Symposium on Automated. High-Resolution Analyses in the Clinical Laboratory. March, 13–141969. Oak Ridge National Laboratory, Oak Ridge, Tenn
   Google Scholar
• Van Dreal P. A. Preliminary evaluation of the Union Carbide CentrifiChem Analyzer. Clin. Chem. 1970; 16: 530
   Web of Science ®Google Scholar
• Daly J., Fabiny D., Ertingshausen G. CentrifiChem, a high-speed analyzer for the clinical laboratory. Clin. Chem. 1970; 16: 530
   Web of Science ®Google Scholar
• Tiffany T. O., Chilcote M. E. An approach to diagnostic enzyme profiles through the use of a multichannel, parallel, fast analyzer. presented at the Third Annual Symposium on High-Resolution Analyses and Advanced Analytical Concepts for the Clinical Laboratory. March, 11–121971. Oak Ridge National Laboratory, Oak Ridge, Tenn
   Google Scholar
• Rubin M., Knott L., Ellis R. W. Routine use of the GeMSAEC (ENI) for kinetic enzymology in clinical chemistry. presented at the Third Annual Symposium on High-Resolution Analyses and Advanced Analytical Concepts for the Clinical Laboratory. March, 11–121971. Oak Ridge National Laboratory, Oak Ridge, Tenn
   Google Scholar
• Fast Analyzer Workshop. Dan Baer, workshop director, Fall Meeting of the American Society of Clinical Pathologists, Boston, Mass., Oct. 29, 1971
   Google Scholar
• GeMSAEC Fast Analyzer Workshop, Burtis C. A. Workshop Coordinator. December, 6–81971. Oak Ridge National Laboratory, Oak Ridge, Tenn
   Google Scholar
• Chilcote M. E., Tiffany T. O., Johnson W. F. A long-term evaluation of performance characteristics of the Union Carbide CentrifiChem parallel analyzer. Clin. Chem 1971; 17: 659
   Web of Science ®Google Scholar
• Bakshy S., Young B. A., Changus G. W. Use of the CentrifiChem Fast Analyzer for the kinetic assay of serum enzymes. Clin. Chem. 1973; 19: 640
   Web of Science ®Google Scholar
• Cross R., Savory J., Heintges G. M. The Aminco RotoChem. II. Parallel fast analyzer - an evaluation. Clin. Chem 1973; 19: 641
   Web of Science ®Google Scholar
• Alpert N. I. Instrument series: report No. 8-centrifugal fast analyzers. Lab World 1973; 27
   Google Scholar
• Alpert N. L. Instrument series: report No. 9-centrifugal fast analyzers (continued). Lab World 1973; 33
   Google Scholar
• Chong-Kit R. Comparison of two high-speed centrifugal analyzers. Clin. Chem. 1973; 19: 641
   Web of Science ®Google Scholar
• Adams R. K. Application of small computers as thermometry research tools. Temperature, Its Measurement and Control in Science and Industry. Instrument Society of America, Pittsburgh 1972; 4: 1445, (2)
   Google Scholar
• Daly J. A., Ertingshausen G. Direct method for determining inorganic phosphate in serum with the “CentrifiChem, “. Clin. Chem. 1972; 18: 263
   PubMed Web of Science ®Google Scholar
• Ertingshausen G., Fabiny-Byrd D. L., Tiffany T. O., Casey S. J. A single reagent method for the rapid determination of total bilirubin on the CentrifiChem Analyzer. Clin. Chem. 1973; 19
   Web of Science ®Google Scholar
• Fabiny-Byrd D. L., Ertingshausen G. Kinetic method for determining acid phosphatase activity in serum with the use of the “CentrifiChem, “. Clin. Chem. 1972; 18: 841
   PubMed Web of Science ®Google Scholar
• Daly J. A., Hinman C. D., Ertingshausen G. An automated uric acid test for the CentrifiChem Analyzer using a direct uricase reagent. Clin. Chem. 1973; 19: 674
   Web of Science ®Google Scholar
• Tiffany T. O., Johnson W. F., Chilcote M. E. Feasibility of multiple simultaneous enzymes assays, for diagnostic purposes, with the GeMSAEC Fast Analyzer. Clin. Chem. 1971; 17: 715
   PubMed Web of Science ®Google Scholar
• Statland B. E., Nishi H. H., Young D. S. Serum alkaline phosphatase: total activity and isoenzyme determinations made by use of the centrifugal fast analyzer. Clin. Chem. 1972; 18: 1468
   PubMed Web of Science ®Google Scholar
• Tiffany T. O., Jansen J. M., Burtis C. A., Overton J. B., Scott C. D. Enzymatic kinetic rate and end-point analyses of substrates, by use of a GeMSAEC Fast Analyzer. Clin. Chem. 1972; 18: 829
   PubMed Web of Science ®Google Scholar
• Nipper H. C., Knoblock E. C., Telesforo G. R. Microanalysis for glucose and bilirubin using a centrifugal fast analyzer. Clin. Chem. 1972; 18: 687
   Web of Science ®Google Scholar
• Swain R. R., Chilcote M. E. The use of the CentrifiChem Fast Analyzer for the determination of conjugated (direct) serum bilirubin. Clin. Chem. 1972; 18: 688
   Web of Science ®Google Scholar
• Koch T. R., Chilcote M. E. A fixed-time kinetic method for the determination of total protein on the CentrifiChem. Clin. Chem. 1972; 18: 688
   Web of Science ®Google Scholar
• Burtis C. A., Mailen J. C., Scott C. D., Johnson W. F., Tiffany T. O., Overton J. B., Gravity Zero (G) Analytical Clinical Laboratory System Annual Progress Report for the Period April 1, 1971 to March 31, 1972, ORNL-TM-3792, Oak Ridge National Laboratory, Oak Ridge, Tenn., July 1972, 117
   Google Scholar
• Slickers K. A., Edwards L., Daly J., Ertingshausen G. Automated reaction-rate method for the direct determination of total serum cholesterol by use of the “CentrifiChem” parallel fast analyzer. Clin. Chem. 1973; 19: 937
   PubMed Web of Science ®Google Scholar
• Tiffany T. O., Morton J. M., Hall E. M., Garrett A. S., Jr. Kinetic enzymic fixed-time and integral analysis of serum triglycerides, a clinical evaluation. Clin. Chem., (submitted for publication)
   Google Scholar
• Olson A. D., Brennan R. L. Ratiometric triglyceride analysis by use of a CentrifiChem Analyzer. Clin. Chem. 1973; 19: 1060
   PubMed Web of Science ®Google Scholar
• Bowie L., Gochman N. A new spectrophotometric enzymatic determination of serum triglycerides. Clin. Chem. 1973; 19: 656
   Web of Science ®Google Scholar
• Chong-Kit R. Rapid and accurate determination of triglycerides utilizing a new program to extrapolate to zero time on the GeMSAEC instrument. Clin. Chem. 1973; 19: 674
   Web of Science ®Google Scholar
• Gonzalez K. H., Knoblock E. C. Microanalysis for triglycerides using the centrifugal fast analyzer. Clin. Chem. 1973; 19: 642
   Web of Science ®Google Scholar
• Burtis C. A., Mailen J. C., Johnson W. F., Scott C. D., Tiffany T. O., Watsky M. B. Gravity Zero (G) Analytical Clinical Laboratory System, Progress Report for the Period August 1 to October 31, 1972, ORNL-TM-4027, Oak Ridge National Laboratory, Oak Ridge, Tenn., February 1973, 39
   Google Scholar
• Smith M. D., Robeis R. W., Grenshaw M. A., Greyson J. An all-solid-state electrochemical electrolyte analyzer. Clin. Chem. 1973; 19: 891
   PubMed Web of Science ®Google Scholar
• Reimer S. M., Levy A., Levy G. L. Automated potentiometric measurement of electrolytes in biological fluids. Clin. Chem. 1973; 19: 659
   Web of Science ®Google Scholar
• Williams G. Z., Young D. S., Stein M. R., Cotlove E. Biological and analytical components of variation in long-term studies of serum constituents in normal subjects. I. Objectives, subject selection, laboratory procedures, and estimation of analytical deviation. Clin. Chem. 1970; 16: 1017
   Web of Science ®Google Scholar
• Harris K. E., Kanofsky P., Shakarji G., Cotlove E. Biological and analytical components of variation in long-term studies of serum constituents in normal subjects. II. Estimating biological components of variation. Clin. Chem. 1970; 16: 1022
   PubMed Web of Science ®Google Scholar
• Cotlove E., Harris K. E., Williams G. Z. Biological and analytical components of variation in long-term studies of serum constituents in normal subjects. III. Physiological and medical implications. Clin. Chem. 1971; 16: 1028
   Web of Science ®Google Scholar
• Johnson W. F., Chilcote D. D. The contribution of spectrophotometry noise to the analytical variation of kinetic enzyme assays: a study of digital instrumentation. Clin. Chem. 1971; 17: 632
   Web of Science ®Google Scholar
• Maclin E. A system analysis of GeMSAEC precision used as a kinetic enzyme analyzer. Clin. Chem. 1971; 17: 707
   PubMed Web of Science ®Google Scholar
• Maclin E., Rohlfing D., Ansour M. Relationship between variables in instrument performance and results of kinetic enzyme assays-a system view. Clin. Chem. 1973; 19: 832
   PubMed Web of Science ®Google Scholar
• Tiffany T. O., Burtis C. A., Anderson N. G. Fast Analyzers for Biochemical Analysis in Methods in Enzymology, S. Flieschman. Academic Press, New York, Vol. 31 A, 87, (in press)
   Google Scholar
• Ayres G. H. Evaluation of accuracy in photometric analysis. Anal. Chem. 1949; 21: 652
   Web of Science ®Google Scholar
• Hughes H. K. Beer's law and the optimum transmittance in absorption measurements. Appl. Optics 1963; 2: 937
   Web of Science ®Google Scholar
• Ingle J. D., Jr., Crouch S. R. Signal-to-noise ratio comparison of photomultipliers and phototubes. Anal. Chem. 1971; 43: 1331
   Web of Science ®Google Scholar
• Ingle J. D., Jr., Crouch S. R. Critical comparison of photon counting and direct current measurement techniques for quantitative spectrophotometric methods. Anal. Chem. 1972; 44: 785
   PubMed Web of Science ®Google Scholar
• Parrat G. L. Probability and Experimental Errors in Science. John Wiley & Sons, Inc., New York 1961; 109
   Google Scholar
• Malmstadt H. V., Delaney C. J., Cordos E. A. Reaction-rate methods of chemical analysis. CRCCrit. Rev. Anal. Chem, L. Meites, 1972; Vol. 2: 4, 559
   Google Scholar
• Young D. S., Thomas D. W., Friedman R. B., Pestaner L. C. Effects of drugs on clinical laboratory tests. Clin. Chem. 1972; 18: 1041
   PubMed Web of Science ®Google Scholar
• Hicks G. P., Ziesemer R. A., Tietz N. W. The use of laboratory computers in monitoring kinetic enzyme assays. Clin. Chem. 1973; 19: 27
   PubMed Web of Science ®Google Scholar
• Henry R. J., Chiamori N., Golub O. J., Berkman S. Revised spectrophotometric methods for the determination of SGOT, SGPT and LDH. Am. J. Clin. Pathol 1960; 34: 381
   PubMed Web of Science ®Google Scholar
• Bishop M. J., Everse J., Kaplan N. O. Identification of lactate dehydrogenase isoenzymes by rapid kinetics. Prop. Natl. Acad. Sci. 1972; 69: 1761
   PubMed Web of Science ®Google Scholar
• Methods of Enzymatic Analysis, H. U. Bergmeyer. Academic Press, New York 1970
   Google Scholar
• Hillmann G. FortlaufenderPhotometrische Messung der sauren phosphatatase-Aktivitat. Z. Klin. Chem. Klin. Biochem. 1971; 3: 273
   Google Scholar
• Swain R. R., Pragay D. A., Chilcote D. D. Determination of SGOT and SGPT on the CcntrifiChem: effect of supplementing sera with pyridoxal-5-phosphate (PY5P). Clin. Chem. 1973; 19: 665
   Web of Science ®Google Scholar
• Hammes G. G. Relaxation Spectrometry of Biological Systems in Advances in Protein Chemistry, C. B. Anfinsen, Jr., J. T. Edsall, M. L. Anson, F. N. Richards. Academic Press, New York 1968; Vol. 23: 1
   Google Scholar
• Velick S. F., Vabra J. A kinetic and equilibrium analysis of the glutamic oxaloacetate transaminase mechanism. J. Biol. Chem. 1962; 237: 2109
   PubMed Web of Science ®Google Scholar
• Meister A., Sober H. A., Peterson E. A. Studies on the coenzyme activation of glutamic aspartic apotransaminase. J. Biol. Chem. 1954; 206: 89
   PubMed Web of Science ®Google Scholar
• Hamfelt A. The effect of pyridoxal phosphate on the aminotransferase assay in blood. Scand. J. Clin. Lab. Invest. 1966, Suppl. 99: 18, 181
   Google Scholar
• Rej R., Fasce C. F., Vanderline R. E. Increased aspartate amino-transferase activity of serum after in vitro supplementation with pyridoxal phosphate. Clin. Oiem. 1973; 19: 92
   Google Scholar
• Ury A. G., Chassy J. R. Increased activity of serum aspartate aminotransferase in the presence of added pyridoxal-5-phosphate. Clin. Chem. 1973; 19: 140
   PubMed Web of Science ®Google Scholar
• de Ritis R., Coltori M., Giusti G. Diagnostic value and pathogenic significance of transaminase activity changes in viral hepatitis. Minerva Med. 1956; 47: 167
   PubMedGoogle Scholar
• Wilkinson J. H. Clinical significance of enzyme activity measurements. Clin. Chem. 1970; 16: 882
   PubMed Web of Science ®Google Scholar
• Tiffany T. O., Chilcote D. D., Burtis C. A. Evaluation of kinetic enzyme parameters by use of a small computer interfaced “fast analyzer” - an addition to automated clinical enzymology. Clin. Chem. 1973; 19: 909
   Web of Science ®Google Scholar
• Eggert A. A., Hicks G. P., Davis J. E. ELLA (The Experimental LINC-Laboratory Analytical System) applied to experimental control. Anal Chem. 1971; 43: 736
   Web of Science ®Google Scholar
• Hicks G. P., Eggert A. A., Toren E. O. Application of an on-line computer to the automation of analytical experiments. Anal Chem. 1970; 42: 729
   Web of Science ®Google Scholar
• Wilkinson C. N. Statistical estimations in enzyme kinetics. Biochem. J. 1961; 80: 324
   PubMed Web of Science ®Google Scholar
• Johansen G., Mumry R. Statistical analysis of enzymic steady-state rate data. C. R. Trav. Lab. Carhberg 1961; 32: 185
   PubMedGoogle Scholar
• Cleland W. W. The statistical analysis of kinetic data. Adv. Enzymol 1967; 29: 1
   PubMedGoogle Scholar
• Cleland W. W. Steady-State Kinetics in Enzymes, P. D. Boyer. Academic Press, New York 1970; 1
   Google Scholar
• Ingle J. D., Jr., Crouch S. R. Theoretical and experimental factors influencing the accuracy of analytical rate measurements. Anal Chem. 1971; 43: 697
   Web of Science ®Google Scholar
• Guilbault G. C. Enzymatic Methods of Analysis. Pergamon Press, New York 1970; 114
   Google Scholar
• Kachmar J. F. Enzymes. Fundamentals of Clinical Chemistry, W. Tietz. W. B. Saunders Co., Philadelphia 1970; 387
   Google Scholar
• Slein M. W. Di-glucose determination with hexokinase and glucose-6-phosphate dehydrogenase. Methods of Enzymatic Analysis, H. U. Bergmeyer. Academic Press, New York 1965; 117
   Google Scholar
• Olive C., Levy H. R. The preparation and some properties of crystalline glucose-6-phosphate dehydrogenase from leuconostic mesenteroides. Biochemistry 1967; 6: 730
   PubMed Web of Science ®Google Scholar
• Peterson J. I., Young D. S. Evaluation of the hexokinase/glucose-6-phosphate dehydrogenase method of determination of glucose in urine. Anal Biochem. 1968; 23: 301
   PubMed Web of Science ®Google Scholar
• Widdowson G. M., Penton J. R. Determination of serum or plasma glucose on the “auto Analyzer II” by use of the hexokinase reaction. Clin. Chem. 1972; 18: 299
   PubMed Web of Science ®Google Scholar
• Neeley W. E. Simple automated determination of serum or plasma glucose by a hexokinase/glucose-6-phosphate dehydrogenase. Clin. Chem. 1972; 18: 509
   PubMed Web of Science ®Google Scholar
• Blume P. Experience with the GeMSAEC Fast Analyzer at the University of Minnesota. Enzymology in Medicine, P. Blume. Academic Press, New York 1974
   Google Scholar
• Andres R. Diabetes and aging. Hosp. Pract. October, 1967; 63
   Google Scholar
• O'SuIlivan J. B., Mahon C. M. Evaluation of age-adjusted criteria for potential diabetes. Diabetes 1971; 20: 811
   PubMed Web of Science ®Google Scholar
• Bucolo G., David H. Quantitative determination of serum triglycerides by use of enzymes. Clin. Chem 1973; 19: 476
   PubMed Web of Science ®Google Scholar
• Eggstein M., Kreutz F. H. Eine Neue Bestimmung der Neutral Fette in Blutserum and Gewebe. Klin. Wochenschr. 1966; 44: 262
   PubMedGoogle Scholar
• Wieland O. Glycerol. Methods of Enzymatic Analysis, H. U. Bergmeyer. Academic Press, New York 1963; 211
   Google Scholar
• Kessler G., Lederer H. Fluorometric Measurement of Triglycerides in Automation in Analytical Chemistry, L. T. Skeggs, et al. Technicon Symposia, 1965, Mediad, New York 1966; 341
   Google Scholar
• Wood P. D. S., Stern M. P., Silvers A., Reaven G. M., von der Groeben J. Prevalence of plasma lipoprotein abnormalities in a free living population of the Central Valley, California. Circulation 1972; 45: 114
   PubMed Web of Science ®Google Scholar
• Harlan W. R., Shaw W. A. Interpretation of hyperlipidemias. CRC Crit. Rev. Clin. Lab. Sci, J. W. King, W. R. Faulkner, 1972; 3: 451
   Google Scholar
• Frederickson D. S., Levey R. I. Familial hyperlipoproteinemia. The Metabolic Basis of Inherited Disease3rd ed., J. B. Stanbury, J. B. Wyngaarden, D. S. Fredrickson. McGraw-Hill, New York 1972; 545
   Google Scholar
• Roch-Ramd F. An enzymic and fluorophotometric method for estimating urea concentrations in nanoliter specimens. Anal. Biochem 1967; 21: 372
   PubMed Web of Science ®Google Scholar
• Kaplan A. The determination of urea, ammonia and urease. Methods of Biochemical Analysis, D. Glock. John Wiley & Sons, Inc., New York 1969; Vol. 17: 311
   Google Scholar
• Menke W. W. Standard reference materials for clinical measurements. Anal Chem. 1971; 43: 28A
   Web of Science ®Google Scholar
• Mahler J. L. A new bacterial uricase for uric acid determinations. Anal Biochem. 1970; 38: 65
   PubMed Web of Science ®Google Scholar
• Jaffi M. Über den Niederschlag, Welchen Pikrinsaeure in Normalem Ham erzeugt and ueber eine neue Reaction des Kreatinins. Z. Physiol Chem. 1886; 10: 391
   Google Scholar
• Owen J. A., Iggo B., Scandrett F. J., Stewart D. R. The determination of creatinine in plasma or serum and in urine: a critical examination. Biochem. J. 1964; 58: 426
   Google Scholar
• Dubos R., Miller B. F. The production of bacterial enzymes capable of decomposing creatinine. J. Biol Chem. 1937; 121: 429
   Google Scholar
• Peters J. P., Van Slyke D. D. Quantitative Clinical Chemistry. Williams and Wilkins, Baltimore 1932; Vol. 2: 598
   Google Scholar
• Stoten A. A. A micromethod for creatinine using resin to remove interfering substances. J. Med. Lab. Technol 1968; 25: 240
   Google Scholar
• Hillmann G., Beyer G. Rapid diazo method for determination of total bilirubin with a mixed reagent. Z. Klin. Chem. 1967; 5: 92
   PubMedGoogle Scholar
• Jackson S. H., Hernandez A. H. A new bilirubinometer and its use in estimating total and conjugated bilirubin in serum. Clin. Chem. 1970; 16: 462
   PubMed Web of Science ®Google Scholar
• Henry R. J. Clinical Chemistry Principles and Techniques5th ed. Hoeber Medical Division, Harper and Row, Publishers, New York 1968; 599
   Google Scholar
• Crouch S. R., Malmstadt H. V. A mechanistic investigation of molybdenum blue method for the determination of phosphate. Anal Chem. 1967; 39: 1084
   Web of Science ®Google Scholar
• Fishe C. H., Subbarow Y. The colorimetric determination of phosphorus. J. Biol. Chem. 1925; 66: 375
   Google Scholar
• Pesce M. A., Bodourian S. S. Bilirubin interference with ultraviolet determination of inorganic phosphate on the “CentrifiChem, “. Clin Chem. 1973; 19: 436
   PubMed Web of Science ®Google Scholar
• Hatcher D. W., Anderson N. G. GeMSAEC, a new analytical tool for clinical chemistry, total serum protein with the biuret reaction. Am J. Clin. Pathol. 1969; 52: 645
   PubMed Web of Science ®Google Scholar
• Weichselbaum T. E. An accurate and rapid method for the determination of proteins in small amounts of blood serum and blood plasma. Am. J. Clin. Pathol 1946; 10: 40
   PubMedGoogle Scholar
• Flegg H. M. An investigation of the determination of serum cholesterol by an enzymatic method (Ames Award Lecture 1972). Ann. Clin. Biochem. 1973; 10: 79
   Google Scholar
• Wybenga D. R., Pileggi V. J., Dirstine P. H., Di Giorgia J. A direct manual determination of serum total cholesterol with a single stable reagent. Clin. Chem. 1970; 16: 980
   PubMed Web of Science ®Google Scholar
• Abell L. L., Levy B., Brodie B. B., Kendall C. A simplified method for the estimation of total cholesterol in serum and demonstration of specificity. J. Biol Chem. 1952; 195: 357
   PubMed Web of Science ®Google Scholar
• McArthur M., Chong-Kit R. Multiple wavelength readings on the ENI GeMSAEC for ketogenic steroids. Clin. Chem. 1973; 19: 659
   Web of Science ®Google Scholar
• Johnson G. F. 1973, personal communication
   Google Scholar