Newer Aspects of Pernicious Anemia

References

• Minot G. R., Murphy W. P. Treatment of pernicious anemia by a special diet. JAMA 1926; 87: 470
   Google Scholar
• Kass L. Pernicious Anemia. W. B. Saunders, Philadelphia 1976
   Google Scholar
• Ehrlich P. Über Regeneration und Degeneration rother Blutscheiben bei Anämien. Berl. Klin. Wochenschr. 1880; 117(28)405
   Google Scholar
• Cabot R. C. A Guide to the Clinical Examination of the Blood for Diagnostic Purposes, 3rd ed. William Wood, New York 1898
   Google Scholar
• Ehrlich P., Lazarus A. Anemia. Histology of the Blood. Normal and pathologic. Diseases of the Blood, A. Stengel. W. B. Saunders, Philadelphia 1905; 17
   Google Scholar
• Kass L. Bone Marrow Interpretation. Charles C Thomas, Springfield 1973
   Google Scholar
• Kass L. A clockface chromatin pattern in the intermediate megaloblast of vitamin B12 or folate deficiency. Blood 1968; 32: 711
   PubMedGoogle Scholar
• Schnitzer B., Aikawa M., Spencer H. H. Pernicious anemia. An ultrastructural study of the bone marrow before and after vitamin B12 therapy. Am. J. Clin. Pathol. 1972; 58: 1
   PubMedGoogle Scholar
• Finne P. H., Skoglund R., Wetterhaus S. Urinary erythropoietin excretion during initial treatment of pernicious anemia. Scand J. Haematol. 1973; 10: 62
   PubMedGoogle Scholar
• Bessis M. Living Blood Cells and Their Ultrastructure. Springer-Verlag, New York 1973
   Google Scholar
• Lessin L. S., Bessis M. Morphology of the erythron. Hematology, W. J. Williams, E. Beutlef, A. J. Erslev, R. N. Rundles. McGraw-Hill, New York 1972; 77
   Google Scholar
• London I. M., West R. The formation of bile pigment in pernicious anemia. J. Biol. Chem. 1950; 184: 359
   PubMed Web of Science ®Google Scholar
• Myhre E. Studies on megaloblasts in vitro. II. Maturation of nucleated red cells in pernicious anemia before and during treatment with vitamin B12. Scand. J. Clin, Lab. Invest. 1964; 16: 320
   PubMed Web of Science ®Google Scholar
• Messner H., Fliedner T. M., Cronkite E. P. Kinetics of erythropoietic cell proliferation in pernicious anemia. Ser. Haematol. 1969; 2(4)44
   Google Scholar
• Wickramasinghe S. N., Chalmers D. G., Cooper E. H. Disturbed proliferation of erythropoietic cells in pernicious anaemia. Nature (London) 1967; 215: 189
   PubMedGoogle Scholar
• Wickramasinghe S. N., Cooper E. H., Chalmers D. G. A study of erythropoiesis by combined morphologic, quantitative cytochemical and autoradiographic methods. Blood 1968; 31: 304
   PubMedGoogle Scholar
• Wickramasinghe S. N., Chalmers D. G., Cooper E. H. Arrest of cell proliferation and protein synthesis in megaloblasts of pernicious anemia. Acta Haematol. 1969; 41: 65
   PubMedGoogle Scholar
• Cooper E. H., Wickramasinghe S. N. Quantitative cytochemistry in the study of erythropoiesis. Ser. Haematol 1969; 2(4)65
   Google Scholar
• Kass L. Unusual morphologic abnormalities of megaloblasts in pernicious anemia and folate deficiency. Am. J. Clin. Pathol. 1976; 65: 117
   Google Scholar
• Cabot R. C. Ring bodies (nuclear remnants?) in anemic blood. J. Med Res. 1903; 9: 15
   PubMedGoogle Scholar
• Schleicher E. M. The origin and nature of the Cabot ring bodies of erythrocytes. J. Lab. Clin. Med. 1942; 27: 983
   Google Scholar
• Lindemann B. Über die Natur der sogenannten Cabotschen Ringkörper der Erythrozyten. Arch. Exp. Pathol. Pharmakol. 1949; 207: 67
   Google Scholar
• Picard D. Nature et signification des anneaux de Cabot des haematies. C. R. Soc. Biol. 1953; 147: 1451
   PubMedGoogle Scholar
• Van Oye E. L'origine des anneaux de Cabot. Rev. Hematol. 1954; 9: 173
   PubMedGoogle Scholar
• Bostrom L. La formation des anneaux de Cabot. Sang 1947; 18: 67
   PubMedGoogle Scholar
• Discombe G. L'origine des corps de Howell-Jolly et des anneaux de Cabot. Sang 1948; 19: 262
   Google Scholar
• Kass L. Origin and composition of Cabot rings in pernicious anemia. Am. J. Clin. Pathol. 1975; 64: 53
   PubMedGoogle Scholar
• Isaacs R. The erythrocyte. Handbook of Hematology, H. Downey. Hoeber Medical Division, New York 1938; Vol 1: 25
   Google Scholar
• Tsamboulas N., Malikiosis X. Zur Frage des Cabotschen Ringkörpers. Dtsch. Arch. Klin. Med. 1939; 184: 183
   Google Scholar
• Kass L., Schnitzer B. Refractory Anemia. Charles C Thomas, Springfield 1975
   Google Scholar
• Kass L., Gray R. H. Ultrastructural visualization of Cabot rings in pernicious anemia. Experientia 1976; 32: 507
   PubMedGoogle Scholar
• Black M. M., Ansley H. R. Antigen-induced changes in lymphoid cell histones. I. Thymus. J. Cell Biol. 1965; 26: 201
   PubMedGoogle Scholar
• Robbing E., Borun T. W. The cytoplasmic synthesis of histones in HeLa cells and its relationship to DNA replication. Proc. Nat. Acad. Sci. USA 1967; 57: 409
   PubMedGoogle Scholar
• Kass L. Demonstration of histones in proerythroblasts in pernicious anemia and the DiGuglielmo syndrome. J. Histochem. Cytochem. 1972; 20: 817
   PubMed Web of Science ®Google Scholar
• Kass L. Histone biosynthesis in pernicious anemia proerythroblasts and megaloblasts. Blood 1973; 41: 549
   PubMedGoogle Scholar
• Horrigan D., Jarrold T., Vilter R. W. Direct action of vitamin B12, upon human bone marrow. J. Clin. Invest. 1951; 30: 31
   PubMedGoogle Scholar
• Allfrey V. G. Functional and metabolic aspects of DNA-associated proteins. Histones and Nucleohistones, D. M. P. Phillips. Plenum Press, New York 1971; 241
   Google Scholar
• Hnilica L. S. The Structure and Biological Function of the Histones. CRC Press, Cleveland 1972
   Google Scholar
• Kass L., Gray R. H. Ultrastructural localization of histones in chronic erythremic myelosis. Am. J. Pathol. 1975; 81: 493
   PubMedGoogle Scholar
• Rozenszajn L., Leibovich M., Shoham D., Epstein J. The esterase activity in megaloblasts, leukaemic and normal haematopoietic cells. Br. J. Haematol. 1968; 14: 605
   PubMed Web of Science ®Google Scholar
• Kass L., Peters C. L. Nonspecific esterase activity in pernicious anemia and chronic erythremic myelosis. A cytochemical and electrophoretic study. Am. J. Clin. Pathol. 1977; 68: 273
   PubMed Web of Science ®Google Scholar
• Fisher R., Schmalzl F. Über die Hemmbarkeit der Esteraseaktivität in Blutmonocyten durch Natriumfluorid. Klin. Wochenschr. 1964; 42: 751
   PubMedGoogle Scholar
• Stuart J., Skowron P. N. A cytochemical study of marrow enzymes in megaloblastic anaemia. Br. J. Haematol. 1968; 15: 443
   PubMedGoogle Scholar
• Kass L. Periodic acid-Schiff-positive megaloblasts in pernicious anemia. Am. J. Clin. Pathol. 1977; 67: 371
   PubMedGoogle Scholar
• Kass L., Hadi M. Z. Phosphorylase activity in chronic erythremic myelosis. Am. J. Clin. Pathol. 1975; 64: 503
   PubMed Web of Science ®Google Scholar
• Hayhoe F. G. J., Quaglino D., Doll R. The Cytology and Cytochemistry of the Acute Leukaemias. A study of 104 cases. Medical Research Council Special Report Series #304, H.M. Stationery Office, London 1964
   Google Scholar
• Swanson C. P. Cellular Physiology. Prentice-Hall, New York 1974
   Google Scholar
• Silber R., Moldow C. F. The biochemistry of B12 -mediated reactions in man. Am. J. Med. 1970; 48: 549
   PubMed Web of Science ®Google Scholar
• Kass L. Pink staining of pernicious anemia megaloblasts by alizarine Red S. Am. J. Clin. Pathol. 1974; 62: 511
   PubMedGoogle Scholar
• Gompertz D. The metabolic effects of an impaired methylmalonyl CoA mutase. The Cobalamins, H. R. V. Arnstein, R. J. Wrighton. Churchill Livingstone, Edinburgh 1971; 101
   Google Scholar
• Nixon P. F., Bertino J. R. Interrelationships of vitamin B12, and folate in man. Am. J. Med. 1970; 48: 555
   PubMedGoogle Scholar
• Mahoney M. J., Rosenberg L. E. Inherited defects of B12, metabolism. Am. J. Med. 1970; 48: 584
   PubMedGoogle Scholar
• Cox E. V., White A. M. Methylmalonic acid excretion: an index of vitamin B12 deficiency. Lancet 1962; 2: 853
   PubMedGoogle Scholar
• Taylor R. T., Weissbach H. N5 -methyltetrahydrofolate-homocysteine methyltransferases. The Enzymes, 3rd ed., P. D. Boyer. Academic Press, New York 1973; 9(B): 121
   Google Scholar
• Kass L. Detection of methionine in pernicious anemia megaloblasts and in other types of erythroid precursors. Am. J. Clin. Pathol. 1976; 65: 504
   PubMedGoogle Scholar
• Kass L. Cytochemical identification of homocysteine in pernicious anemia and chronic erythremic myelosis. Am. J. Clin. Pathol. 1977; 67: 53
   PubMedGoogle Scholar
• Hatch F. T., Larrabee A. R., Cathou R. E., Buchanan J. M. Enzymatic synthesis of the methyl group of methionine. I. Identification of the enzymes and cofactors involved in the system isolated from Escherichia coli. J. Biol. Chem. 1961; 236: 1095
   PubMedGoogle Scholar
• Taylor R. T., Hanna M. L., Hutton J. J. 5-Methyltetrahydrofolate homocysteine cobalamin methyltransferases in human bone marrow and its relationship to pernicious anemia. Arch. Biochem. Biophys. 1974; 165: 787
   PubMedGoogle Scholar
• Taylor R. T. Methylcobalamin as a substrate at a separate site on Escherichia coli B N5 -methyltetrahydrofolate-homocysteine cobalamin methyltransferase. Arch. Biochem. Biophys. 1971; 144: 352
   PubMedGoogle Scholar
• Noronha J. M., Silverman M. On folic acid, vitamin B12, methionine, and formiminoglutamic acid metabolism. Vitamin B12, und Intrinsic Factor. Second European Symposium, H. C. Heinrich. Enke, Stuttgart 1962
   Google Scholar
• Herbert F., Zalusky R. Interrelations of vitamin B12 and folic acid metabolism: folic acid clearance studies. J. Clin. Invest. 1962; 41: 1263
   PubMed Web of Science ®Google Scholar
• Herbert V. Recent developments in cobalamin metabolism. The Cobalamins., H. R. V. Arnstein, R. J. Wrighton. Churchill Livingstone, Edinburgh 1971; 2
   Google Scholar
• Blakley R. L. The Biochemistry of Folic Acid and Related Pteridines. Frontiers of Biology. North-Holland, Amsterdam 1969; Vol. 13: 439
   Google Scholar
• Buchanan J. M., Elford H. L., Loughlin R. E., McDougall B. M., Rosenthal S. The role of vitamin B12 in methyl transfer to homocysteine. Ann. N. Y. Acad. Sci. 1964; 112: 756
   PubMedGoogle Scholar
• Buchanan J. M. The function of vitamin B12, and folic acid coenzyme in mammalian cells. Medicine (Baltimore) 1964; 43: 697
   PubMedGoogle Scholar
• Johns D. G., Bertino J. R. Folates and megaloblastic anemia. A review. Clin. Pharmacol. Ther. 1965; 6: 372
   PubMedGoogle Scholar
• Metz J., Kelly A., Swett V. C., Waxman S., Herbert V. Deranged DNA synthesis by bone marrow from vitamin B12, -deficient humans. Br. J. Haematol. 1968; 14: 575
   PubMed Web of Science ®Google Scholar
• Nixon P. F., Bertino J. R. Impaired utilization of serum folate in pernicious anemia. A study with radiolabeled 5-methyltetrahydrofolate. J. Clin. Invest. 1972; 51: 1431
   PubMedGoogle Scholar
• Sakamoto S., Niina M., Tahaku F. Thymidylate synthetase activity in bone marrow cells in pernicious anemia. Blood 1975; 46: 699
   PubMedGoogle Scholar
• Haurani F. Vitamin B12 and the megaloblastic development. Science 1973; 182: 78
   PubMed Web of Science ®Google Scholar
• Kass L. Acetylation and methylation of histones in pernicious anemia. Blood 1974; 44: 125
   PubMedGoogle Scholar
• Donohue D. M., Azzam S. A. Incorporation of H3 thymidine and H2 deoxyuridine with the DNA of bone marrow from patients with pernicious anemia. Clin. Res. 1962; 10: 108
   Google Scholar
• Killmann S. A. Effect of deoxyuridine on incorporation of tritiated thymidine: difference between normoblasts and megaloblasts. Acta Med. Scand. 1964; 175: 483
   PubMedGoogle Scholar
• Chanarin I., Perry J., Lumb M. The biochemical lesion in vitamin B12 deficiency in man. Lancet 1974; 1: 1251
   PubMedGoogle Scholar
• Pedersen J., Lund J., Ohlsen A. J., Kristensen H. P.Φ. Partial megaloblastic erythropoiesis in elderly achlorhydric patients with mild anaemia. Lancet 1957; 1: 448
   Google Scholar
• Van der Weyden M., Rother M., Firkin B. Megaloblastic maturation masked by iron deficiency: a biochemical basis. Br. J. Haematol. 1972; 22: 299
   PubMed Web of Science ®Google Scholar
• Wickramasinghe S. N., Longland J. E. Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro. Acta Haematol. 1974; 52: 14
   PubMedGoogle Scholar
• Bock H. E., Hartje J., Müller D., Wilmanns W. Thyminnucleotidsynthese und Proliferation von Knochenmarkzellen bei megaloblastären Anämien unter der Einwirkung von Vitamin B12. Klin. Wochenshr. 1967; 45: 176
   PubMedGoogle Scholar
• Frenkel E. P., Kitchens E. L. Intracellular localization of hepatic propionyl CoA carboxylase and methylmalonyl-CoA mutase in human and normal and vitamin B12 -deficient rats. Br. J. Haematol. 1975; 31: 501
   PubMedGoogle Scholar
• Cannata J. J. B., Focesi A., Mazumder R., Warner R. C., Ochoa S. Metabolism of propionic acid in animal tissues. XII. Properties of mammalian methylmalonyl coenzyme A mutase. J. Biol. Chem. 1965; 240: 3249
   PubMed Web of Science ®Google Scholar
• Kellermeyer R. W., Allen S. H. G., Stjernhofan R., Wood H. G. Methylmalonyl isomerase IV. Purification and properties of the enzyme from propionibacteria. J. Biol. Chem. 1964; 239: 2562
   PubMed Web of Science ®Google Scholar
• Frenkel E. P., Kitchens R. L., Hersh L. B., Frenkel R. Effect of vitamin B12 deprivation on the in vivo levels of coenzyme A intermediates associated with propionate metabolism. J. Biol. Chem. 1974; 249: 6984
   PubMedGoogle Scholar
• Cox E. V., Robertson-Smith D., Small M., White A. M. The excretion of propionate and acetate in vitamin B, deficiency. Clin. Sci. 1968; 35: 123
   PubMedGoogle Scholar
• Vivacqua R. J., Myerson R. M., Prescott D. J., Raboinowitz J. L. Abnormal propionic-methylmalonic-succinic acid metabolism in vitamin B12 deficiency and its possible relationship to the neurologic syndrome of pernicious anemia. Am. J. Med. Sci. 1966; 251: 507
   PubMedGoogle Scholar
• Frenkel E. P. Abnormal fatty acid metabolism in peripheral nerves of patients with pernicious anemia. J. Clin. Invest. 1973; 52: 1237
   PubMed Web of Science ®Google Scholar
• Chanarin I. The Megaloblastic Anaemias. Blackwell Scientific, Oxford 1969
   Google Scholar
• Pratt J. M. Inorganic Chemistry of Vitamin B₁₂. Academic Press, London 1972
   Google Scholar
• Hoffbrand A. V. Megaloblastic Anaemia. W. B. Saunders, London 1976
   Google Scholar
• Glass G. B. J., Boyd L. J., Rubenstein M. A., Svigals C. S. Relationship of glandular mucoprotein from human gastric juice to Castle's intrinsic antianemic factor. Science 1952; 115: 101
   PubMedGoogle Scholar
• Hoedemaeker P. J., Abels J., Wachters J. J., Arends A., Nieweg H. O. Further investigations about the site of production of Castle's gastric intrinsic factor. Lab. Invest. 1966; 15: 1163
   PubMedGoogle Scholar
• Fisher J. M., Taylor K. B. A comparison of autoimmune phenomena in pernicious anemia and chronic atrophic gastritis. N. Engl J. Med. 1965; 272: 499
   PubMed Web of Science ®Google Scholar
• Glass G. B. J. Gastric intrinsic factor and its function in the metabolism of vitamin B12. Physiol. Rev. 1963; 43: 529
   PubMed Web of Science ®Google Scholar
• Gräsbeck R., Simons K., Sinkkonen I. Isolation of intrinsic factor and its probable degradation product, as their vitamin B12 complexes, from human gastric juice. Biochim. Biophys. Acta 1966; 127: 47
   PubMed Web of Science ®Google Scholar
• Gräsbeck R. Intrinsic factor and the transcobalamin. Scand J. Clin. Lab. Invest. Suppl. 1967; 95: 7
   PubMedGoogle Scholar
• Herbert V., Streiff R. R., Sullivan W. L. Notes on vitamin B12 absorption, autoimmunity, and childhood pernicious anemia; relation of intrinsic factor to blood group substance. Medicine 1964; 43: 679
   PubMedGoogle Scholar
• McGuigan J. E. Measurement of the affinity of human gastric intrinsic factor for cyanocobalamin. J. Lab. Clin. Med 1967; 70: 666
   PubMed Web of Science ®Google Scholar
• Gottlieb C. W., Retief F. P., Herbert V. Blockade of vitamin B12 - binding sites in gastric juice, serum, and saliva by analogues and derivatives of vitamin B12 and by antibody to intrinsic factor. Biochim. Biophys. Acta 1967; 141: 560
   PubMedGoogle Scholar
• Schade S. G., Feick P. L., Muckerheide M., Schilling R. F. Occurrence in gastric juice of antibody to a complex of intrinsic factor and vitamin B12. N. Engl J. Med. 1966; 275: 528
   PubMed Web of Science ®Google Scholar
• Booth C. C., Molun D. C. The site of absorption of vitamin B12 in man. Lancet 1959; 1: 18
   PubMed Web of Science ®Google Scholar
• Donaldson R. M., Mackenzie I. L., Trier J. S. Intrinsic factor-mediated attachment of vitamin B12 to brush borders and microvillous membranes of hamster intestine. J. Clin. Invest 1967; 46: 1215
   PubMed Web of Science ®Google Scholar
• Peters T. J., Hoffbrand A. V. Absorption of vitamin B12 by the guinea-pig; The role of the ileal mitochondrion. The Cobalamins, H. R. V. Arnstein, R. J. Wrighton. Churchill Livingstone, Edinburgh 1971; 61
   Google Scholar
• Routhenberg S. P., Huhti A. L. Identification of a macromolecular factor in the ileum which binds intrinsic factor and immunologic identification of intrinsic factor in ileal extracts. J. Clin. Invest. 1968; 47: 913
   PubMedGoogle Scholar
• Castle W. B. Development of knowledge concerning the gastric intrinsic factor and its relation to pernicious anemia. N. Engl. J. Med. 1953; 249: 603
   PubMed Web of Science ®Google Scholar
• Castle W. B. Factors involved in the absorption of vitamin B12. Gastroenterology 1959; 37: 377
   PubMedGoogle Scholar
• Castle W. B. Current concepts of pernicious anemia. Am. J. Med. 1970; 48: 541
   PubMed Web of Science ®Google Scholar
• Corcino J. J., Waxman S., Herbert V. Absorption and malabsorption of vitamin B12. Am. J. Med 1970; 48: 562
   PubMed Web of Science ®Google Scholar
• Herbert V. Studies on the role of intrinsic factor in vitamin B12 absorption, transport and storage. Am. J. Clin. Nutr. 1959; 7: 433
   PubMedGoogle Scholar
• Herbert V., Castle W. B. Intrinsic factor. N. Engl. J. Med. 1964; 270: 1181
   PubMedGoogle Scholar
• Waxman S., Corcino J. J., Herbert V. Drugs, toxins, and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization. Am. J. Med. 1970; 48: 599
   PubMed Web of Science ®Google Scholar
• Ardeman S., Chanarin I., Berry V. Studies on human gastric intrinsic factor. Observations on its possible absorption and enterohepatic circulation. Br. J. Haematol. 1965; 11: 11
   PubMedGoogle Scholar
• Hines J. D., Rosenberg A., Harris J. W. Intrinsic factor-mediated radio-B12 uptake in sequential incubation studies using everted sacs of guinea pig small intestine: evidence that intrinsic factor is not absorbed into the intestinal cell. Proc. Soc. Exp. Biol. Med. 1968; 129: 653
   PubMedGoogle Scholar
• Farrant P. C. Nuclear changes in oral epithelium in pernicious anemia. Lancet 1958; 1: 830
   PubMedGoogle Scholar
• Graham R. M., Rheault M. H. Characteristic cellular changes in epithelial cells in pernicious anemia. J. Lab. Clin. Med. 1954; 42: 235
   Google Scholar
• Massey B. W., Rubin C. E. The stomach in pernicious anemia: a cytologic study. Am. J. Med. Sci. 1954; 227: 481
   PubMedGoogle Scholar
• Sauli S., Astaldi G., Malossini L. Histopathology of intestinal mucosa obtained by Crosby's biopsy in pernicious anemia before and after vitamin B12 treatment. Acta Vitaminol. 1963; 17: 143
   PubMedGoogle Scholar
• Foroozan P., Trier J. S. Mucosa of the small intestine in pernicious anemia. N. Engl. J. Med. 1967; 277: 553
   PubMed Web of Science ®Google Scholar
• Pena A. S., Callender S. T., Truelove S. C., Whitehead R. Small intestinal mucosal abnormalities and disaccharidase activity in pernicious anaemia. Br. J. Haematol. 1972; 23: 313
   PubMed Web of Science ®Google Scholar
• Abe T., Gibbs B., Cooper B. A. Forms of vitamin B12 in blood and bone marrow in patients with pernicious anaemia. Brit. J. Haematol. 1975; 31: 493
   PubMedGoogle Scholar
• Linnell J. C., Hoffbrand A. V., Peters J. V., Matthews D. M. Estimation of individual plasma B12 compounds in normal subjects and patients with deranged B12 metabolism. J. Clin. Pathol. 1969; 22: 742
   PubMedGoogle Scholar
• Pitney W. R., Beard M. F., VanLoon E. J. Observations on the bound form of vitamin B12 in human serum. J. Biol. Chem. 1954; 207: 143
   PubMed Web of Science ®Google Scholar
• Mendelsohn R. S., Wathin D. M., Horbett A. P., Fahey J. L. Identification of the vitamin B12 -binding protein in the serum of normals and of patients with chronic myelocytic leukemia. Blood 1958; 13: 740
   PubMed Web of Science ®Google Scholar
• Hall C. A., Finkler A. E. In vivo plasma vitamin B12 binding in B12 deficient and nondeficient subjects. J. Lab. Clin. Med. 1962; 60: 765
   PubMed Web of Science ®Google Scholar
• Hall C. A. Transcobalamin I and II as natural transport proteins of vitamin B12. J. Clin. Invest. 1975; 56: 1125
   PubMed Web of Science ®Google Scholar
• Allen R. H. Annotation: The plasma transport of vitamin B12. Br. J. Haematol. 1976; 33: 161
   PubMed Web of Science ®Google Scholar
• Hall C. A., Finkler A. E. The dynamics of transcobalamin II. A vitamin B12 binding substance in plasma. J. Lab. Clin. Med. 1965; 65: 459
   PubMed Web of Science ®Google Scholar
• Hall C. A., Finkler A. E. Function of transcobalamin II. A vitamin B12 binding substance in human plasma. Proc. Soc. Exp. Biol. Med. 1966; 123: 55
   PubMed Web of Science ®Google Scholar
• Hall C. A., Finkler A. E. Protein-mediated uptake of vitamin B12 by cells in tissue culture. The Cobalamins, H. R. V. Arnstein, R. J. Wrighton. Churchill Livingstone, Edinburgh 1971; 49
   Google Scholar
• Zittoun J., Zittoun R., Marquet J., Sultan C. The three transcobalamins in myeloproliferative disorders of acute leukaemia. Br. J. Haematol. 1975; 3: 287
   Google Scholar
• Hall C. A., Finkler A. E. Vitamin B12 binding protein in polycythemia vera plasma. J. Lab. Clin. Med. 1969; 73: 60
   PubMed Web of Science ®Google Scholar
• Bloomfield F. J., Scott J. M. Identification of a new vitamin B12 binder (Transcobalamin III) in normal human serum. Br. J. Haematol. 1972; 22: 33
   PubMed Web of Science ®Google Scholar
• Gizis E. J., Ley L. M. Separation of transcobalamin on small DEAE cellulose column. Proc. Soc. Exp. Biol. Med. 1972; 140: 326
   PubMed Web of Science ®Google Scholar
• Cooper B. A., Paranchych W. Selective uptake of specifically bound cobalt-58 vitamin B12 by human and mouse tumor cells. Nature (London) 1961; 191: 393
   PubMed Web of Science ®Google Scholar
• Paranchych W., Cooper B. A. Factors influencing the uptake of cyanocobalamin (vitamin B12) by Ehrlich ascites carcinoma cells. Biochim. Biophys. Acta 1962; 60: 393
   PubMedGoogle Scholar
• Retief F. P., Gottlieb C. W., Herbert V. Mechanism of vitamin B12 uptake by erythrocytes. J. Clin. Invest. 1966; 45: 1907
   PubMed Web of Science ®Google Scholar
• Herbert V., Sullivan L. W. Activity of coenzyme B12 in man. Ann. N. Y. Acad. Sci. 1964; 112: 855
   PubMedGoogle Scholar
• Beck W. S. Vitamin B12 deficiency. Hematology, W. J. Williams, E. Beulter, A. J. Erslev, R. W. Rundles. McGraw-Hill, New York 1972; 256
   Google Scholar
• Harrison R. J. Vitamin B12 levels in erythrocytes in normal subjects and in pernicious anaemia. J. Clin. Pathol. 1970; 23: 219
   PubMedGoogle Scholar
• Davis D. W., Heathcoate J. G., Mooney F. S. Aminoaciduria in pernicious anaemia. J. Clin. Pathol. 1969; 22: 742
   Google Scholar
• Beck W. S. Metabolic functions of vitamin B12. The possible relationship of megaloblast formation to unbalanced growth in bacteria requiring vitamin B12. J. Clin. Invest. 1961; 40: 1024
   Google Scholar
• Beck W. S., Goulian M., Hook S. The metabolic function of vitamin B12. II. Participation of vitamin B12 in the biosynthesis of deoxyribonucleic acid and its acid soluble precursors. Biochim. Biophys. Acta 1962; 55: 470
   Google Scholar
• Beck W. S., Hook S., Barnett B. H. The metabolic functions of vitamin B12. I. Distinctive modes of unbalanced growth behavior in Lactobacillus leichmannii. Biochim. Biophys. Acta 1962; 55: 455
   PubMedGoogle Scholar
• Beck W. S. The metabolic basis of megaloblastic erythropoiesis. Medicine 1964; 43: 715
   PubMed Web of Science ®Google Scholar
• Powsner E. R., Berman L. Human bone marrow chromosomes in megaloblastic anemia. Blood 1965; 26: 784
   PubMedGoogle Scholar
• Tidwell T., Allfrey V. G., Mirsky A. E. The methylation of histones during regeneration of the liver. J. Biol. Chem. 1968; 243: 707
   PubMed Web of Science ®Google Scholar
• Finch C. A., Coleman D. H., Motulsky A. G., Donohue D. M., Reiff R. H. Erythrokinetics in pernicious anemia. Blood 1956; 11: 807
   PubMed Web of Science ®Google Scholar
• Peabody F. W., Broun G. D. Phagocytosis by erythrocytes in the bone marrow with special reference to pernicious anemia. Am. J. Pathol. 1925; 1: 169
   PubMedGoogle Scholar
• Ashby W. Study of transfused blood. II. Blood destruction in pernicious anemia. J. Exp. Med. 1921; 34: 147
   PubMedGoogle Scholar
• Wearn J. T., Warren S., Ames O. The length of life of transfused erythrocytes in patients with primary and secondary anemia. Arch. Intern. Med. 1922; 29: 527
   Google Scholar
• Hamilton H. E., Sheets R. F., DeGowin E. L. Studies with inagglutinable erythrocyte counts. VII. Further investigation of the hemolytic mechanism in untreated pernicious anemia and the demonstration of a hemolytic property in the plasma. J. Lab. Clin. Med. 1958; 51: 942
   PubMed Web of Science ®Google Scholar
• Jedlicka V. Über die Lebertherapie und das Wesen der perniziösen Anämie. Folia Haematol. (Leipzig) 1930; 42: 359
   Google Scholar
• Lynch E. C., Alfrey C. P., Jr. Studies in vitro on the autohemolysis of normoblastic and megaloblastic marrow cells. Texas Rep. Biol. Med. 1966; 24: 180
   PubMedGoogle Scholar
• Astaldi G. Differentiation, proliferation and maturation of haematopoietic cells studied in tissue culture. Ciba Foundation Symposium on Haemopoiesis: Cell Production and its Regulation, G. E. W. Wolstenholme, M. O'Connor. Little, Brown, Boston 1960; 99
   Google Scholar
• Lajtha L. G. An inhibitory factor in pernicious anaemia serum. Clin. Sci. 1950; 9: 287
   PubMedGoogle Scholar
• Callender S. T., Lajtha L. G. On the nature of Castle's hemopoietic factor. Blood 1951; 6: 1234
   PubMed Web of Science ®Google Scholar
• Thompson R. B. Addisonian pernicious anaemia. Confirmatory evidence of a factor inhibiting erythropoiesis. Clin. Sci. 1950; 9: 281
   PubMedGoogle Scholar
• Zarafonetis C. J. D., Overman R. L., Molthan L. Unique sequence of pernicious anemia, polycythemia, and acute leukemia. Blood 1957; 12: 1011
   PubMedGoogle Scholar
• Nelson V. G., Jensen M. K. Pernicious anaemia and acute leukaemia. A case report with cytogenetic studies. Scand. J. Haematol. 1970; 7: 26
   PubMedGoogle Scholar
• Kiossoglou K. A., Mitus W. J., Dameshek W. Chromosomal aberration in pernicious anemia. Study of three cases before and after therapy. Blood 1965; 25: 662
   PubMed Web of Science ®Google Scholar
• Heath C. W., Jr. Cytogenetic observations in vitamin B12 and folate deficiency. Blood 1966; 27: 800
   PubMed Web of Science ®Google Scholar
• Corcino J. J., Zaiusky F., Greenberg M., Herbert V. Coexistence of pernicious anaemia and chronic myeloid leukaemia: an experiment of nature involving vitamin B12 metabolism. Br. J. Haematol. 1971; 20: 511
   PubMed Web of Science ®Google Scholar
• Harker L. A., Finch C. A. Thrombokinetics in man. J. Clin. Invest. 1969; 48: 963
   PubMed Web of Science ®Google Scholar
• Gaspar S. Untersuchung en über Urspung, Zahl und Form der Blutplattchen und über das Benehmen der Knochenmarksriesenzellen (Megakaryozyten) unter normalen und pathologischen Verhältnissen. Frankf. Z. Pathol. 1926; 34: 460
   Google Scholar
• Fontana L. Osservazioni sul midollo osseo esaminato in vivo in casi di anemia perniciosa. Arch. Sci. Med. 1928; 52: 497
   Google Scholar
• Jones O. P. Cytological studies of biopsied pernicious anemia bone marrow during relapse. Proc. Soc. Exp. Biol. Med. 1936; 34: 694
   Google Scholar
• Liu Y. K., Sullivan L. W. Marrow granulocyte reserve in pernicious anemia. Clin. Res. 1966; 14: 321
   Google Scholar
• Perillie P. E., Kaplan S. S., Finch S. C. Significance of changes in serum muramidase activity in megaloblastic anemia. N. Engl. J. Med. 1967; 277: 10
   PubMedGoogle Scholar
• Wickramasinghe S. N., Pratt J. R. Myelocyte proliferation in pernicious anaemia. Acta Haematol. 1970; 44: 37
   PubMedGoogle Scholar
• Arneth J. Diagnose und Therapie der Anaemien. Stuber, Würzburg 1907; 61
   Google Scholar
• Kaplan S. S., Basford R. E. Effect of vitamin B12 and folic acid deficiencies on neutrophil function. Blood 1976; 47: 801
   PubMedGoogle Scholar
• Doig A., Girdwood R. H., Duthie J. J. R., Knox J. D. E. Response of megaloblastic anaemia to prednisolone. Lancet 1957; 2: 966
   Web of Science ®Google Scholar
• Carmel R., Herbert V. Presence of “precipitating” or “blocking” antibody to intrinsic factor in gastric juice or serum of nearly all pernicious anemia patients. Clin. Res. 1966; 14: 482
   Google Scholar
• Herbert V. Immunologic factors in pernicious anemia. Postgrad. Med. 1967; 42: 298
   PubMed Web of Science ®Google Scholar
• Jeffries G. H., Sleisenger M. H. Studies of parietal cell antibody in pernicious anemia. J. Clin. Invest 1965; 44: 2021
   PubMed Web of Science ®Google Scholar
• Carmel R., Herbert V. Intrinsic-factor antibody in the saliva of a patient with pernicious anemia. Lancet 1967; 1: 80
   PubMedGoogle Scholar
• Haushy J., Korman M. G., Sovney D., St John D. J. B. Radio-immunoassay of gastrin: studies in pernicious anaemia. Gut 1971; 12: 97
   PubMedGoogle Scholar
• Yalow R. S., Berson S. A. Size and charge distinctions between endogenous human plasma gastrin in peripheral blood and heptadecapeptide gastrins. Gastroenterology 1970; 58: 609
   PubMed Web of Science ®Google Scholar
• Korman M. G., Soveny C., Hansky P., II. Studies in pernicious anaemia and the Zollinger-Ellison syndrome. Gut 1973; 14: 459
   PubMedGoogle Scholar
• Piper P. W., Fenton B. H., Croydon M., Clarke A. D. The peptide fraction of gastric juice. A study of the peptides of gastric juice in normal persons and patients with peptic ulcer, gastric carcinoma, and pernicious anaemia. Scand. J. Gastroenterol. 1972; 7: 113
   PubMedGoogle Scholar
• Ardeman S., Chanarin L. Steroids and Addisonian pernicious anemia. N. Engl. J. Med. 1965; 273: 1352
   PubMed Web of Science ®Google Scholar
• Kristensen H. P.ø., Friis T. The mechanism of the prednisone effect upon B12 absorption in pernicious anaemia. Acta Med. Scand. 1960; 168: 457
   PubMedGoogle Scholar
• Baur S., Fisher J. M., Strickland R. G., Taylor K. B. Autoantibody-containing cells in the gastric mucosa in pernicious anaemia. Lancet 1968; 2: 881
   Google Scholar
• Adams J. F., Glen A. I. M., Kennedy E. H., MacKenzie I. L., Morrow J. M., Anderson J. R., Gray K. G., Middleton D. G. The histological and secretory changes in the stomach in patients with autoimmunity to gastric parietal cells. Lancet 1964; 2: 401
   Google Scholar
• Fisher J. M., Taylor K. B. A comparison of autoimmune phenomena in pernicious anemia and chronic atrophic gastritis. N. Engl. J. Med. 1965; 272: 499
   PubMed Web of Science ®Google Scholar
• Hoedemaeker P. J., Ito S. Ultrastructural localization of gastric parietal cell antigen with peroxidase coupled antibody. Lab. Invest. 1970; 22: 184
   PubMed Web of Science ®Google Scholar
• Jacob E., Glass G. B. J. Separation of intrinsic factor antibodies from parietal cell antibodies in pernicious anemia serum by gel filtration. Proc. Soc. Exp. Biol. Med. 1971; 137: 243
   PubMedGoogle Scholar
• Tai C., McGuigan J. E. Immunologic studies in pernicious anemia. Blood 1969; 34: 63
   PubMed Web of Science ®Google Scholar
• Goldberg L. S., Cunningham J. E., Teresalii P. I. Lymphocytotoxin and pernicious anemia. Blood 1972; 39: 862
   PubMedGoogle Scholar
• Das K. C., Hoffbrand A. V. Lymphocyte transformation and megaloblastic anaemia: Morphology and DNA synthesis. Br. J. Haematol. 1970; 19: 459
   PubMed Web of Science ®Google Scholar
• Goldstone A. H., Calder E. A., Barnes E. W., Irvine W. J. The effect of gastric antigens on the in vivo migration of leucocytes from patients with atrophic gastritis and pernicious anaemia. Clin. Exp. Immunol. 1973; 14: 501
   PubMed Web of Science ®Google Scholar
• MacCuish A. C., Urbaniak S. J., Goldstone A. M., Irvine W. J. PHA responsiveness and subpopulations of circulating lymphocytes in pernicious anemia. Blood 1974; 44: 849
   PubMedGoogle Scholar
• Grunnet I., Horwitz J., Reymann F., Schwartz M. Vitiligo and pernicious anemia. Arch. Dermatol. 1970; 101: 82
   Google Scholar
• Tudhope G. R., Wilson G. M. Anaemia in hypothyroidism. Q. J. Med. 1968; 53(29)513
   Google Scholar
• Tudhope G. R., Wilson G. M. Deficiency of vitamin B12 in hypothyroidism. Lancet 1962; 1: 703
   PubMed Web of Science ®Google Scholar
• Lerman J., Means J. H. The gastric secretion in exophthalmic goitre and myxoedema. J. Clin. Invest. 1932; 11: 167
   PubMedGoogle Scholar
• Selwyn J. G., Alexander S. S. A positive Coombs reaction in pernicious anemia. Br. Med. J. 1951; 1: 564
   PubMedGoogle Scholar
• Krylov A. A., Chigirinsky A. N. On the autoimmune component of the genesis of Addison-Biermer's anemia. Ter. Arkh. 1965; 37: 103
   PubMedGoogle Scholar
• Farquet J. J., Weber J. J., Rousso C., Cruchard A. Association d'une anémie pernicieuse vraie avec un test de Coombs et un phénomène LE positifs chez une epileptique de 25 ans. Schweiz. Med. Wochenschr. 1967; 97: 1462
   PubMedGoogle Scholar
• Pirofsky B., Vaughn M. Addisonian pernicious anemia with positive antiglobulin tests. Am. J. Clin. Pathol. 1968; 50: 459
   PubMedGoogle Scholar
• Bohnen R. F., Ultman J. E., Gorman J. G., Farhangi M., Scudder J. The direct Coombs' test: its clinical significance. Study in a large university hospital. Ann. Intern. Med. 1968; 68: 19
   PubMedGoogle Scholar
• Beickert A., Friedrich M. Positive autoantibody test on erythrocytes of patients with pernicious anemia. Dtsch. Gesundheitswes. 1969; 24: 1548
   PubMedGoogle Scholar
• Pollock J. G., Fenton E., Barrett K. E. Familial autoimmune haemolytic anaemia associated with rheumatoid arthritis and pernicious anaemia. Br. J. Haematol 1970; 18: 171
   PubMedGoogle Scholar
• Hadnagy C. Sekundäre Immunphänomene in der Hämatologie. Folia Haematol.(Leipzig) 1973; 100: 225
   PubMedGoogle Scholar
• Ghazi H. H. Pernicious anemia and rheumatoid arthritis. Br. Med. J. 1972; 1: 144
   PubMed Web of Science ®Google Scholar
• Klayman M. I., Brandborg L. Clinical application of Co60 -labeled vitamin B12 urine test. N. Engl. J. Med. 1955; 253: 808
   PubMedGoogle Scholar
• Editorial, Immunoglobulin deficiency and pernicious anaemia. Lancet 1970; 1: 458
   Google Scholar
• Gelfand E. W., Berkel A. I., Godwin H. A., Rocktin R. E., David J. R., Rosen F. S. Pernicious anaemia, hypogammalogulinaemia, and altered lymphocyte reactivity. A family study. Clin. Exp. Immunol. 1972; 11: 187
   PubMedGoogle Scholar
• Twomy J. J., Jordan P. H., Jarrold T., Trubowitz S., Ritz N. D., Cohn H. O. The syndrome of immunoglobulin deficiency and pernicious anemia. Am. J. Med. 1969; 47: 340
   PubMedGoogle Scholar