31
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Serum Levels of Glycosyltransferases and Related Glycoproteins as Indicators of Cancer: Biological and Clinical Implications

, &
Pages 189-239 | Published online: 27 Sep 2008

References

  • Podolsky D. K., Weiser M. M. Galactosyltransferase activities in human sera: detection of a cancer-associated isoenzyme. Biochem. Biophys. Res. Commun. 1975; 65: 545
  • Weiser M. M., Podolsky D. K., Isselbacher K. J. Cancer-associated isoenzyme of serum galactosyltransferase. Proc. Natl. Acad. Sci. U.S.A. 1976; 73: 1319
  • Podolsky D. K., Weiser M. M., Isselbacher K. J., Coben A. M. A cancer-associated galactosyltransferase isoenzyme. N. Engl. J. Med. 1978; 299: 703
  • Bauer C., Kottgen E., Reutter W. Elevated activities of a-2- and a-3-fucosyltransferases in human serum as a new indicator of malignancy. Biochem. Biophys. Res. Commun. 1977; 76: 488
  • Khilanani P., Chou T.-H., Ratanatharathorn V., Kessel D. Evaluation of two plasma fucosyltransferases as marker enzymes in non-Hodgkin's lymphoma. Cancer 1978; 41: 701
  • Chatterjee S. K., Kim U. Fucosyltransferase activity in metastasizing and nonmetastasizing rat mammary carcinomas. J. Natl. Cancer Inst. 1978; 61: 151
  • Kessel D., Allen J. Elevated plasma sialyltransferase in the cancer patient. Cancer Res. 1975; 35: 670
  • Chatterjee S. K., Bhattacharya M., Barlow J. J. Elevated activity of cytidine 5′-monophospho-N-acetylneuraminic acid hydrolase in serum of ovarian cancer patients as a possible indicator of malignancy. Biochem. Biophys. Res. Commun. 1978; 80: 826
  • Winzler R. J. Carbohydrates in cell surfaces. International Review of Cyrology, G. H. Bourne, J. F. Danielli. Academic Press, New York 1970; 77
  • Fox T. O., Shepard J. R., Burger M. M. Cyclic membrane changes in animal cells: transformed cells permanently display a surface architecture detected in normal cells only during mitosis. Proc. Natl. Acad. Sci. U.S.A. 1971; 68: 244
  • Wallenfels B. Developmental and mutational changes of glycoproteins in the mouse neuronal retina: studies with bovine galactosyltransferase. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 3223
  • Roth S. A molecular model for cell interactions. Q. Rev. Biol. 1973; 48: 541
  • Roseman S. The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. Chem. Phys. Lipids 1970; 5: 270
  • Balsamo J., McDonough J., Lilien J. Retinal tectal connection in the embryonic chick: evidence for regionally specific cell surface components which mimic the pattern of innervation. Dev. Biol. 1976; 49: 338
  • Rees D. A., Lloyd C. W., Thom D. Control of grip and stick in cell adhesion through lateral relationships of membrane glycoproteins. Nature (London) 1977; 267: 124
  • Shin S.-L., Freedman V. H., Risser R., Pollack R. Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro. Proc. Natl. Acad. Sci. U.S.A. 1975; 72: 4435
  • Abercrombie M., Ambrose E. J. The surface properties of cancer cells: a review. Cancer Res. 1962; 22: 525
  • Gahmberg C. G., Nilsson K., Andersson L. C. Specific changes in the surface glycoprotein pattern of human promyelocytic leukemic cell line HL-60 during morphologic and functional differentiation. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 4087
  • Wright T. C., Ukena T. E., Campbell R., Karnovsky M. J. Rates of aggregation, loss of anchorage dependence, and tumorigenicity of cultured cells. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 258
  • Davey G. C., Currie G. A., Alexander P. Spontaneous shedding and antibody induced modulation of histocompatibility antigens on murine lymphoma: correlation with metastatic capacity. Brit. J. Cancer 1976; 33: 9
  • Burridge K. Changes in cellular glycoproteins after transformation: identification of specific glycoproteins and antigens in sodium dodecyl sulfate gels. Proc. Natl. Acud. Sci. U.S.A. 1976; 73: 4457
  • Warren L., Buck C. A., Tuszynski G. P. Glycopeptide changes and malignant transformation, a possible role for carbohydrate in malignant behavior. Biochim. Biophys. Acta. 1978; 516: 97
  • Buck C. A., Glick M. C., Warren L. Glycopeptides from the surface of control and virustransformed cells. Science 1971; 172: 169
  • Warren L., Zeidman I., Buck C. A. The surface glycoproteins of a mouse melanoma growing in culture and as a solid tumor in, vivo. Cancer Res. 1975; 35: 2186
  • Parry G., Hawkes S. P. Detection of an early surface change during oncogenic transformation. Proc. Natl. Acad. Sci. U.S.A. 1978; 75: 3703
  • Hynes R. O. Role of surface alterations in cell transformation: the importance of proteases and surface proteins. Cell 1974; 1: 147
  • Chen L. B., Gallimore P. H., McDougall J. K. Correlation between tumor induction and the large external transformation sensitive protein on the cell surface. Proc. Natl. Acad. Sci. U.S.A. 1976; 73: 3570
  • Kornfeld R., Kornfeld S. Comparative aspects of glycoprotein structure. Annu. Rev. Biochem. 1976; 45: 217
  • Kobata A. Structures and functions of the sugar chains of cell surface glycoproteins. Cell Struct. Function 1979; 4: 169
  • Pigman W. Submandibular and sublingual glycoproteins. The Glyconjugates, M. I. Horowitz, W. Pigman. Academic Press, New York 1977; Vol. I: 137
  • Marshall R. D. The nature and metabolism of the carbohydrate-peptide linkages of glycoproteins. Biochem. Soc. Symp. 1974; 40: 17
  • Hasilik A., Rome L. H., Neufeld E. F. Processing of lysosomal enzymes in human skin fibroblasts. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1979; 38: 467
  • Prehm P., Scheid A., Choppin P. W. The carbohydrate structure of the glycoproteins of the paramyxovirus SVS grown in bovine kidney cells. J. Biol. Chem. 1979; 254: 9669
  • Bretscher M. S. Membrane structure: Some general principles. Science 1973; 181: 622
  • Rothman J. E., Lenard J. Membrane asymmetry. Science 1977; 195: 743
  • Blobel G., Dobberstein B. Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains and membrane-bound ribosomes of murine myeloma. J. Cell Biol. 1975; 67: 835
  • Blobel G., Dobberstein B. Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components. J. Cell Biol. 1975; 67: 852
  • Blobel G. Intercellular protein topogenesis. Proc. Natl. Acad. Sci. U.S.A. 1980; 77: 1496
  • Kreibich G., Ulrich B. L., Sabatini D. D. Proteins of rough microsomal membranes related to ribosome binding. I. Identification of ribophorins I and II, membrane proteins characteristic of rough microsomes. J. Cell Biol. 1978; 71: 464
  • Schachter H. Subcellular sites of glycosylation. Biochem. Soc. Symp. 1974; 40: 57
  • Shur B. D. Cell-surface glycosyltransferases in gastrulating chick embryos. Dev. Biol. 1977; 58: 40
  • Porter C. W., Bernacki R. J. Ultrastructural evidence for ectoglycosyltransferase systems. Nature (London) 1975; 256: 648
  • Keenan T. W., Morré D. J. Glycosyltransferases: Do they exist on the surface membrane of mammalian cells?. FEBS Lett. 1975; 55: 8
  • Deppert W., Walter G. Cell surface glycosyltransferases—Do they exist?. J. Supramol. Struct. 1978; 8: 19
  • Shur B. D., Roth S. Cell surface glycosyltransferases. Biochim. Biophys. Acta 1975; 415: 473
  • Weiser M. M., Podolsky D. K. Cell surface galactosyltransferase in mitosis, differentiation, neoplastic transformation and metastases. Cell Surface Curbohydrare Chemistry, R. E. Harmon. Academic Press, New York 1978; 67
  • Schachter H. Glycosylation of glycoproteins during intracellular transport of secretory products. Adv. Cytopharmacol 1974; 2: 207
  • Nelson J. D., Jato-Rodriguez J. J., Mookerjea S. The Occurrence and properties of soluble UDP-galactose glycoprotein galactosyltransferase in human amniotic fluid. Can. J. Biochem. 1974; 52: 42
  • Gerber A. C., Kozdrowski I., Wyss S. R., Berger E. G. The change heterogeneity of soluble human galactosyltransferases isolated from milk, amniotic fluid and malignant ascites. Eur. J. Biochem 1979; 93: 453
  • Den H., Kaufman B., Roseman S. Properties of some glycosyltransferases in embryonic chicken brain. J. Biol. Chem. 1970; 245: 6607
  • LaMont J. T., Gammon M. T., Isselbacher K. J. Cell-surface glycosyltransferases in cultured fibroblasts: Increased activity and release during serum stimulation of growth. Proc. Nutl. Acad. Sci. U.S.A. 1977; 74: 1086
  • Parodi A. J., Leloir L. F. The role of lipid intermediates in the glycosylation of proteins in the eucaryotic cell. Biochim. Biophys. Acta 1979; 559: 1
  • Behrens N. H., Leloir L. F. Dolichol monophosphate glucose: an intermediate in glucose transfer in liver. Proc. Natl. Acad. Sci. U.S.A. 1970; 66: 153
  • Cacum J. F., Jackson J. J., Eylar E. H. The biosynthesis of mannose-containing glycoproteins: a possible lipid intermediate. Biochem. Biophys. Res. Commun. 1969; 35: 505
  • Zatz M., Baronda S. H. Incorporation of mannose into mouse brain lipid. Biochem. Biophys. Res. Commun. 1969; 36: 511
  • Lennarz W. J. Lipid linked sugars in glycoprotein synthesis. Science 1975; 188: 986
  • Waechter C. J., Lennarz W. J. The role of polyprenol-linked sugars in glycoprotein synthesis. Annu. Rev. Biochem. 1976; 45: 95
  • Tkacz J. S., Lampen J. O. Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes. Biochem. Biophys. Res. Commun. 1975; 65: 248
  • Leavitt R., Schlesinger S., Kornfeld S. Impared intracellular migration and altered solubility of nonglycosylated glycoproteins of vesicular stomatitis virus and sindbis virus. J. Biol. Chem. 1977; 252: 9018
  • Chapman A., Li E., Kornfeld S. The biosynthesis of the major lipid-linked oligosaccharide of Chinese hamster ovary cells occurs by the ordered addition of mannose residues. J. Biol. Chem. 1979; 254: 10243
  • Hubbard S. C., Robbins P. W. Synthesis and processing of protein-linked oligosaccharides, in vivo. J. Biol. Chem. 1979; 254: 4568
  • Trowbridge I. S., Hyman R. Abnormal lipid-linked oligosaccharides in class E Thy-I-negative mutant lymphomas. Cell 1979; 17: 503
  • Kornfeld S., Gregory W., Chapman A. Class E Thy-I negative mouse lymphoma cells utilize an alternate pathway of oligosaccharide processing to synthesize complex-type oligosaccharides. J. Biol. Chem. 1979; 254: 11649
  • Liu T., Stetson B., Turco S. J., Hubbard S. C., Robbins P. W. Arrangement of glucose residues in the lipid-linked oligosaccharide precursor of asparaginyl oligosaccharides. J. Biol. Chem. 1979; 254: 4554
  • Robbins P. W., Hubbard S. C., Turco S. J., Wirth D. F. Proposal for a common oligosaccharide intermediate in the synthesis of membrane glycoproteins. Cell 1977; 12: 893
  • Spiro M. J., Spiro R. J., Bhoyroo V. D. Glycosylation of proteins by oligosaccharide-lipids, Studies on a thyroid enzyme involved in oligosaccharide transfer and the role of glucose in this reaction. J. Biol. Chem. 1979; 254: 7668
  • Turco S. J., Stetson B., Robbins P. W. Comparative rates of transfer of lipid-linked oligosaccharides to endogenous glycoprotein acceptors in vitro. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 4411
  • Hopwood J. J., Dorfman A. Isolation of lipid glucuronic acid and N-acetylglucosamine from a rat fibrosarcoma. Biochem. Biophy Res. Commun. 1977; 75: 472
  • Weachter C. J., Lucas J. J., Lennarz W. J. Evidence for xylosyl lipids as intermediates in xylosyl transfers in hen oviduct members. Biophys. Res. coomun. 1974; 56: 343
  • Wolf G. Retinol-linked sugars in glycoprotein synthesis. Nutr. Rev. 1977; 35: 97
  • Helting T., Peterson P. A. Galactosyl transfer in mouse satocytoma: synthesis of a galactose-containing polar metabolite of retinol. Biochem. Biophys. Res. commun. 1972; 46: 429
  • Marshall R. D. Glycoprotiens. Annu. Rev. Biochem. 1972; 41: 673
  • Hart G. W., Brew K., Grant G. A., Bradshaw R. A., Lennarz W. J. Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoprotiens. J. Biol. Chem. 1979; 254: 9747
  • Kronquist K. E., Lennarz W. J. Enzymatic conversion of proteins to glycoprteins by lipid-linked sacccharides: a study of potential exogenous acceptor proteins. J. supramol. Struct. 1978; 8: 51
  • Czichi V., Lennarz W. J. Localization of the enzyme system for glycosylation of proteins via the lipid-linked pathway in rough endoplasmic reticulum. J. Biol. chem. 1977; 252: 7901
  • Keily M. L., McKnight G. S., Schimke R. T. Studies on the attachment of carbohydrate to ovalubumin nascent chains in hen oviduct. J. Biol. Chem. 1976; 251: 5490
  • Lingappa V. R., Lingappa J. A., Blobel G. Chicken ovalbumin contains an intgernal signal sequance. Nature (London) 1979; 281: 117
  • Kornfeld S., Li E., Tabas I. The sytehesis of complex-type oligosaccharides. II. Characteriszation of the processing intermediates in the synthesis of teh complex oligosaccharide units of the vascular stomatitis virus G protein. J. Biol. Chem. 1978; 253: 7771
  • Hunt L. A., Etchinson E. R., summers D. F. Oligosaccharide chains are trimmed during sythesis of the envelope glycoprotein of vesicular stomatitis virus. Proc. Natl. Acad. Sci. U.S.A. 1978; 75: 754
  • Tabas I., Schlesinger S., Kornfeld S. Processing of high mannose oligosaccharides to form complex type oligosacchraides on the newly ssyntesized polypeptides of the vesicular stomatitis virus G protein and the IgG heavy chain. J. Biol. chem. 1978; 253: 716
  • Turco S. J., Robbins P. W. The initial stages of processing of protein-bound oligocaccharides in vitro. J. Biol. Chem. 1979; 254: 4560
  • Chen W. W., Lennarz W. J. Enzymatic excision of glucosyl units linked to the oligosaccharide chains of glycoproteins. J. Biol. Chem. 1978; 253: 5780
  • Spiro R. G., Spiro M. J., Bhoyroo V. D. Processing of carbohydrate units glycoproteins. Characterization of thyroid glucosidase. J. Biol. Chem. 1979; 254: 7659
  • Tabas I., Kornfeld S. Purification and characterization of a rat liver Golgi α-mannosidase capable of processing asparagine-linked oligosaccharides. J. Biol. Chem. 1979; 254: 11655
  • Robertson M. A., Etchinson J. R., Robertson J. S., Sommers D. F., Stanley P. Specific changes in the oligosaccharide moieties of VSV grow in different lectin-resistant CHO cells. Cell 1978; 13: 515
  • Li E., Kornfeld S. Structure of the altered oligosaccharide present in glycoproteins from a clone of Chinese hamster ovary cells deficient in N-acetylglucosaminyltransferase activity. J. Biol. Chem. 1978; 253: 6426
  • Wilson J. R., Williams D., Schachter H. The control of glycoprotein synthesis: N-acetylglucosamine linkage to a mannose residue as a signal for the attachement of L-fucose to the asparagine-linked N-acetylglucosamine residue of glycopeptide from α-acid glycoprotein. Biochem. Biophys. Res. Commun. 1976; 72: 909
  • Narasimhan S., Stanley P., Schachter H. Control of glycoprotein synthesis. Lectin-resistant mutant containing only one of two distinct N-acetyglucosa minyltransferase activities present in wild type Chinese hamster ovary cells. J. Biol. Chem. 1977; 252: 3926
  • Hill R. L., Brew K. Lactose synthetase. Adv. Enzymol. 1975; 43: 411
  • Harpaz N., Schachter H. Purification of UDP-GlcN Ac: a-D-mannoside GlcN Ac-transferase I from bovine colostrum and separation from UDP-GlcN Ac: a-D-mannoside GlcN Ac-transferase II. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1979; 38: 292
  • Paulson J. C., Prieels J-P., Glasgow L. R., Hill R. L. Sialyl- and fucosyltransferases in the biosynthesis of asparaginyl-linked glycoproteins. J. Biol. Chem. 1978; 253: 5617
  • Jarnefelt J., Rush J., Li Y.-T., Laine R. A. Erythroglycan, a high molecular weight glycopeptide with the repeating structure ‘galactosyl-(1–4)-2-deoxy-2-aceta midoglycosyl(1–3)’ comprising more than one-third of the protein-bound carbohydrate of human erythrocyte stroma. J. Biol. Chem. 1978; 253: 8006
  • Li E., Gibson R., Korndeld S. Structural of an unusual complex-type ligosaccharide isolated from chinese hamster ovary cells. Arch. Bichem. Biophys. 1980; 199: 393
  • krusius T., Finne J., Rauvala H. The poly (glycosyl) chains of glycoproteins. Eur. J. Biochem. 1978; 92: 289
  • Paulson J. C., Rearick J. I., Hill R. L. Enzymatic characterization of β-D-galactoside α2–6 sialyltransferase from bovine colostrum. J. Biol. Chem. 1977; 252: 2363
  • Rearick J. I., Sadler J. E., Paulson J. C., Hill R. L. Enzymatic characterization of β-D-galactoside α 2–3 sialyltransferase from porcine submaxillary glands. J. Biol. Chem. 1979; 254: 4444
  • Beyer T. A., Rearick J. I., Paulson J. C., Prieels J-P., Sadler J. E., Hill R. L. Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences. J. Biol. Chem. 1979; 254: 12531
  • McGuire E. J., Roseman S. Enzymatic synthesis of the protein-hexosamine linkage in sheep submaxillary mucin. J. Biol. Chem. 1967; 242: 3745
  • Goodwin S. D., Watkins W. M. The peptide moiety of boold-group-specific glycoproteins. Some amino acid sequences in the regions carrying the carbohydrate chains. Eur. J. Biochem. 1974; 47: 371
  • Baenziger J., Kornfeld S. Structure of the carbohydrate units of IgAl immunoglobulin. I. composition, glycopeptide isolation, and structure of the asparagine-linked oligosaccharide units. J. Biol. Chem. 1974; 249: 7260
  • Hagopian A., Westall F. C., Whitehead J. S., Eylar E. H. Glycosylation of the Al protein from myelin by a polypeptide N-acetyl-galactosaminyltransferase. J. Biol. Chem. 1971; 246: 2519
  • Feeney R. E., Yeh Y. Antifreeze proteins from fish bloods. Adv. Protein Chem. 1978; 32: 191
  • Schachter H., McGuire E. J., Roseman S. Sialic acids. XIII. A uridine diphosphate D-galactose: mucin galactosyltransferase from porcine submaxillary gland. J. Biol. Chem. 1971; 246: 5321
  • McGuire E. J. Biosynthesis of submaxillary mucins. Blood and Tissue Antigens, D. Aminoff. Academic Press, New York 1970; 461
  • Carlson D. M., McGuire E. J., Jourdian G. W., Roseman S. The sialic Acids. XVI. Isolation of a mucin sialyltransferase from sheep submaxillary gland. J. Biol. Chem. 1973; 248: 5763
  • Keegstra K., Sefton B., Burke D. Sindbis virus glycoproteins: effect of the host cell on the oligosaccharides. J. Virol 1975; 16: 613
  • Etchison J. R., Holland J. J. Carbohydrate composition of the membrane glycoprotein of vesicular stomatitus virus grown in four mamalian cell lines. Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 4011
  • Weitzman S., Grennon M., Keegstra K. Comparison of sindbis and immunoglobulin glycopeptides in mouse myeloma cells. J. Biol. Chem. 5377; 254: 1979
  • Bernacki R. J., Gurtoo H. L. Differential inhibition of rat liver sialyltransferase(s) by various aflatoxins and their metabolites. Res. Commun. Chem. Pathol. Pharmacol. 1975; 10: 681
  • Hickman J., Ashwell G., Morell A. G., Van den Hamer C. J. A., Scheinberg I. H. Physical and chemical studies on ceruloplamin. VIII. Preparation of N-acetylneuraminic acid-1-14C-labeled ceruloplasmin. J. Biol. Chem. 1970; 245: 759
  • Simmons J. L., Fishman P. H., Freese E., Brady R. O. Morphological alterations and ganglioside sialyltransferase activity induced by small fatty acids in Hela cells. J. Cell Biol. 1975; 66: 414
  • Bernacki R. J. Regulation of rat-liver glycoprtein:N-acetylneuraminic transferase activity by pyrimidine nucleotides. Eur. J. Biochem. 1975; 58: 477
  • Ko G. K., Raghupathy E. Glycoprotein biosynthesis in the developing rat brain. IV. Effects of guanosine nucleotides on soluble glycoprotein galactosyl- and N-acetylgalactosaminyltransferases. Biochim. Biophys. Acta. 1973; 313: 277
  • Mookerjea S., Yung J. W. M. Studies on uridine diphosphate-galactose pyrophosphatase and uridine diphosphate-galactose: glycoprotein galactosyltransferase activities in microsomal membranes. Arch. Biochem. Biophys. 1975; 166: 223
  • Baker A. P., Hillegass L. M. Enhancement of UDP-galactose:mucin galactosyltransferase activity by spermine. Arch. Biochem. Biophys. 1974; 165: 597
  • Kornfeld S., Kornfeld R., Neufeld E. F., O'Brien P. J. The feedback control of sugar nucleotide biosynthesis in liver. Proc. Natl. Acad. Sci. U.S.A. 1964; 52: 371
  • Carraway K. L., Fogle D. D., Chesnut R. W., Huggins J. W., Carraway C. A. C. Ectoenzymes of mammary gland and its tumors. Lectin inhibition of 5′-nucleotidase of the 13762 rat mammary ascites carcinoma. J. Biol. Chem. 1976; 251: 6173
  • Kolata G. B. Embryo development: debate over aggregation factors. Science 1975; 188: 718
  • Steinberg M. S. Does differential adhesion govern self-assembly processes in histogenesis? Equilibrium configurations and the emergence of a hierachy among populations of embryonic cells. J. Exp. Zool. 1970; 173: 395
  • Moscona A. A. Analysis of cell recombinations in experimental synthesis of tissues in vitro. J. Cell Comp. Physiol. Suppl. 1962; 60: 65
  • Turner R. S., Burger M. M. Involvement of a carbohydrate group in the active site for surface guided reassociation of animal cells. Nature (London) 1973; 244: 509
  • Balsamo J., Lilien J. The binding of tissue-specific adhesive molecules to the cell surface. A molecular basis for specificity. Biochemistry 1975; 14: 167
  • Weinbaum G., Burger M. M. Two component system for surface guided reassociation of animal cells. Nature (London) 1973; 244: 510
  • Yoshida K., Haguya M., Yanagishima N. Isolation and purification of the sexual agglutination substance of mating type a cells in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 1976; 71: 1085
  • Winterburn P. J., Phelps C. F. The significance of glycosylated proteins. Nature (London) 1972; 236: 147
  • Culp L. A. Substrate-attached glycoproteins mediating adhesion of normal and virus-transformed mouse fibroblasts. J. Cell Biol. 1974; 63: 71
  • Ekblom P., Alitalo K., Vaheri A., Timpl R., Saxén L. Induction of a basement membrane glycoprotein in embryonic kidney: possible role of laminin in morphogenesis. Proc. Natl. Acad. Sci. U.S.A. 1980; 77: 485
  • Turley E. A., Roth S. Interactions between carbohydrate chians of hyaluronate and chondroitin suiphate. Nature (London) 1980; 283: 268
  • Chipowsky S., Lee Y. C., Roseman S. Adhesion of cultured fibroblasts to insoluble analogues of cell surfece carbohydrates. Proc. Natl. Acad. Sci. U.S.A. 1973; 70: 2309
  • Weigel P. H., Schnaar R. L., Kuhlenschmidt M. S., Schmell E., Lee R. T., Lee Y. C., Roseman S. Adhesion of hepatocytes to immobilized sugars, a threshold phenomenon. J. Biol. Chem. 1979; 254: 10830
  • Asao M. I., Oppenheimer S. B. Inhibition of cell aggregation by specific carbohydrates. Exp. Cell Res. 1979; 120: 101
  • Heifetz A., Lennarz W. J. Biosynthesis of N-glycosidically linked glycoproteins during gastrulation of sea urchin embryos. J. Biol. Chem. 1979; 254: 6119
  • Morell A. G., Gregoriadis G., Scheinberg I. H., Hickman J., Ashwell G. The role of sialic acid in dtermining the survival of glycoproteins in the circulation. J. Biol. Chem. 1971; 246: 1461
  • Pricer W. E., Ashwell G. The binding of desialylated glycoproteins by plasma membranes of rat liver. J. Biol. Chem. 1971; 246: 4825
  • Kawasaki T., Ashwell G. Isolation and characterization of an avian hepatic binding protein specific for N-acetylglucosamine-terminated glycoproteins. J. Biol. Chem. 1977; 252: 6536
  • Steer C. J., Kusiak J. W., Brady R. O., Jones E. A. Selective hepatic uptake of human β-hexosaminidase A by a specific glycoprotein recognition system on sinusoidal cells. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 2774
  • Steer C. J., Clerenberg R. Unique distribution of glycoprotein receptors on parenchymal and sinusoidal cells of rat liver. J. Biol. Chem. 1979; 254: 4457
  • Achord D. T., Brot F. E., Bell C. E., Sly W. S. Human β-glucuronidase: in vivo clearance and in vitro uptake by a glycoprotein recognition system on reticuloendothelial cells. Cell 1978; 15: 269
  • Rome L. H., Weissman B., Neufeld E. F. Direct demonstration of binding of a lysosomal enzyme α-L-induronidase to receptors on cultured fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 2331
  • Brown M. S., Goldstein J. L. Receptor-mediated endocytosis: insights from the lipoprotein receptor system. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 3330
  • Goldstein J. L., Brown M. S. The low-density lipoprotein pathway and its relationship to atherosclerosis. Annu. Rev. Biochem. 1977; 48: 897
  • Chatterjee S., Kwiterovich P. O., Jr., Sekerke C. S. Effects of tunicamycin on the binding and degradation of low density lipoproteins and glycoprotein synthesis in cultured fibroblasts. J. Biol. Chem. 1979; 254: 3704
  • Ruoslahti E. A., Vaheri A., Kuusela P., Linder E. Fibroblast surface antigen: a new serum protein. Biochim. Biophys. Acta. 1973; 322: 352
  • Hynes R. O. Alterations of cell surface proteins by viral transformation and by proteolysis. Proc. Natl. Acad. Sci. U.S.A. 1973; 70: 3170
  • Vaheri A., Ruoslahti E. A. Disappearance of a major cell-type specific surface glycoprotein antigen (SF) after transformation of fibroblasts by Rous sarcoma virus. Int. J. Cancer 1974; 13: 579
  • Linder E., Vaheri A., Ruoslahti E. A., Wartiovaara J. Distribution of fibroblast surface antigen in the developing chick embryo. J. Exp. Med. 1975; 142: 41
  • Chen L. B., Maitland N., Gallimore P. H., McDougall J. K. Detection of the large external transformation-sensitive protein on some epithelial cells. Exp. Cell Res. 1977; 106: 39
  • Kahn P., Shin S-L. Cellular tumorigenicityin nude mice. Test of associations among loss of cell-surface fibronectin, anchorage independence, and tumor-forming ability. J. Cell Biol. 1979; 82: 1
  • Bryant M. L., Stoner G. D., Metzger R. R. Protein-bound carbohydrate content of normal and tumorous human lung tissue. Biophys. Acta 1974; 343: 226
  • Van Beek W. P., Smets L. A., Emmelot P. Changed surface glycoprotein as a marker of malignancy in human leukaemic cells. Nature (London) 1975; 253: 457
  • Burger M. M., Goldberg A. R. Identification of a tumor-specific determination on neoplastic cell surfaces. Proc. Natl. Acad. Sci., U.S.A. 1967; 57: 259
  • Ganguly P., fossett N. G. Role of surface sialic acid in the interaction of wheat germ agglutinin with human platelets. Biochem. Biophys. Res. Commun. 1979; 89: 1154
  • Motamed M., Michal F., Born G. V.R. Increase in sialic acids removable by neuraminidase during the shape change of platelets. Biochem. J. 1976; 158: 655
  • Glick J. L., Goldberg A. R., Pardee A. B. The role of sialic acid in the release of proteins from L1210 leukemic cells. Cancer Res. 1966; 26: 1774
  • Miller S., Hay E., Codington J. Ultrastructural and histochemical differences in cell surface properties of strain-specific and nonstrain-specific TA3 adenocarcinoma cells. J. Cell Biol. 1977; 72: 511
  • Reutter W., Bauer C. Terminal sugars in glycoconjugates: metabolism of free and protein-bound L-fucose, N-acetylneuraminic acid and D-galactose in liver and Morris hepatomas. Morris Hepatomas, H. P. Morris, W. E. Cress. Plenum Press, New York 1978; 405
  • Ogata S-I., Muramatsu T., Kobata A. New structural characteristics of the large glycopeptides from transformed cells. Nature (London) 1976; 259: 580
  • Pouysségur J., Willingham M., Paten I. Role of cell surface carbohydrates and proteins in cell behavior-studies on the biochemical reversion of an N-acetylglucosamine-deficient fibroblast mutant. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 243
  • Barrett J. C., Ts'o P. O. P. Evidence for the progressive nature of neoplastic transformation in, vitro. Proc. Natl. Acad. Sci. U.S.A. 1978; 75: 3761
  • Poste G., Fidler I. J. The pathogenesis of cancer metastases. Nature (London) 1980; 283: 139
  • Herlyn M., Steplewski Z., Herlyn D., Koprowski H. Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 1438
  • Fishman W. H., Inglis N. I., Stolbach L. L., Krnat M. J. A serum alkaline phosphatase isoenzyme of human neoplastic cell origin. Cancer Res. 1968; 28: 150
  • Fishman L., Miyayama H., Driscoil S. G., Fishman W. H. Developmental phase-specific alkaline phosphatase is oenzymes of human placenta and their occurrence in human cancer. Cancer Res. 1976; 36: 2268
  • Ehrmeyer S. L., Joiner B. L., Kahan L., Larson F. C., Metzenberg R. L. A cancer-associated, fast, homoarginine-sensitive electrophoretic form of serum alkaline phosphatase. Cancer Res. 1978; 38: 599
  • Koett J., Howell J., Wolf P. L. The association of an ultrafast alkaline phosphatase isoenzyme with malignancy. Tumor Associated Markers, P. L. Wolf. Masson, New York 1979; 174
  • Bacchus H. Serum glycoproteins and malignant neoplastic disorders. CRC Crit. Rev. Clin. Lab. Sci. 1977; 8: 333
  • Kapeller M., Gal-Oz R., Grover N. B., Doljanski F. Natural shedding of carbohydrate-containing macromolecules from cell surfaces. Exp. Cell Res. 1973; 79: 152
  • Kleinberg D. L. Human α-lactalbumin: measurement in serum and in breast cancer organ cultures by radioimmuno-assay. Science 1975; 190: 276
  • Lieblich J. M., Weintraub B. D., Rosen S. W., Chou J., Robinson J. C. HeLa cells secrete a sub-unit of glycoprotein tropic hormones. Nature (London) 1976; 260: 530
  • Rieber M., Romano E. Transformation dependent modifications in released and cell-bound surface proteins detected by antisera to shed antigens. Cancer Res. 1976; 36: 3568
  • Bernacki R. J., Kim U. Concomitant elevations in serum sialyltransferase activity and sialic acid content in rats with metastasizing mammary tumors. Science 1977; 195: 577
  • Willcox P. Secretion of β-N-acetylglucosaminidase isoenzymes by normal human fibroblasts. Biochem. J. 1798; 173: 433
  • Koch G. L. E., Smith M. J. An association between actin and the major histocompatibility antigen H-2. Nature (London) 1978; 273: 274
  • Klohs W. D., Mastrangelo R., Weiser M. M. Release of glycosyltransferase and glycosidase activities from normal and transformed cell lines. Cancer Res.
  • O-Day W. T., Young R. W. Rhythmic daily shedding of outersegment membranes by visual cells in the goldfish. J. Cell Biol. 1978; 76: 593
  • Alexander P. Escape from immune destruction by the host through shedding of surface antigens: is this a characteristic shared by malignant and embryonic cells?. Cancer Res. 1974; 34: 2077
  • Cooper A. G., Codington J. F., Brown M. D. In vivo release of glycoprotein I from the Ha su bline of TA3 murnie tumor into ascites fluid and serum. Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 1224
  • Singer R. M., White L. J., Perry J. E., Doellgast G. J. The releases of high molecular-weight alkaline phosphatase and leucine aminopeptidase into the media of cultured human cells. Cancer Res. 1975; 35: 3048
  • Markert C. L. Neoplasia: a disease of cell differentiation. Cancer Res. 1968; 28: 1908
  • Gold P., Freedman S. O. Specific carcinoembryonic antigens of the human digestive system. J. Exp. Med. 1965; 122: 467
  • Alexander P., Currie G. A., Thompson D. M. P. Immunological Aspects of Neoplasia. Williams & Wilkins, Baltimore 1975
  • Currie G. Immunological aspects of host resistance to the development and growth of cancer. Biochim. Biophys. Acta 1976; 458: 135
  • Weiser M. M., Podoisky D. K. Cancer-associated galactosyltransferase and glycopeptide acceptor activities. Tumor Associated Markers, P. L. Wolf. Masson, New York 1979; 117
  • Nowotny A., Weyer E. M. Molecular biology of gram-negative bacterial lipopolysaccharides. Ann. N. Y. Acad. Sci. 1966; 133: 277
  • Jourdian G. W., Carlson D. M., Roseman S. The enzymatic synthesis of sialyl-lactose. Biochem. Biophys. Res. Commun. 1963; 10: 352
  • Warren L., Fuhrer J. P., Buck C. A. Surface glycoproteins of normal and transformed cells: a difference determined by sialic acid and a growth-dependent sialyl transferase. Proc. Natl. Acad. Sci. U.S.A. 1972; 69: 1838
  • Kessel D., Samson M. K., Shah P., Allen J., Baker L. H. Alterations in plasma sialyltransferese associated with successful chemotherapy of a disseminated tumor. Cancer 1976; 38: 2132
  • Kessel D., Sykes E., Henderson M. Glycosyltransferase levels in tumors merastatic to liver and in uninvolved liver tissue. J. Natl. Cancer Inst. 1977; 59: 29
  • Bosmann H. B., Hall T. C. Enzyme activity in invasive tumors of human breast and colon. Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 1833
  • Kim Y. S., isaacs R. Glycoprotein metabolism in inflammatory and neoplastic diseases of the human colon. Cancer Res. 1975; 35: 2092
  • Kessel D., Chou T-H. Fucosyltransferase levels in plasma and tissues of the cancer patient. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1976; 35: 1442
  • Aip C., Dao T. Alterations in serum glycosyltransferases and 5′-nucleotidase in breast cancer patients. Cancer Res. 1978; 38: 723
  • Chatterjee S. K., Bhattacharya M., Barlow J. J. Glycosyltransferase and glycosidase activities in ovarian cancer patients. Cancer Res. 1979; 39: 1943
  • Silver H. K. B., Karim K. A., Archibald E. L., salinas F. A. Serum sialic acid and sialyltransferase as monitors of tumor burden in malignant melanoma patients. Cancer Res. 1979; 39: 5036
  • Ganzinger V., Moser K. Sialyltransferase activity: a serum enzyme marker in the fellow-up of cancer patients. Recent Results Cancer Res. 1979; 67: 50
  • Weiser M. M., Neumeier M. M., Quaroni A., Kirsch K. Synthesis of plasmalemmal glycoproteins in intestinal epithelial cells. Separation of Golgi membranes from villus and crypt cell surface membranes; glycosyltransferase activity of surface membrane. J. Cell Biol. 1978; 77: 722
  • Aip C. Effect of partial hepatectomy and gydrocortisone administration on liver and serum sialyltransferase activities. Biochim, Biophys. Acta 1979; 583: 14
  • sadler J. E., Rearick J. I., Paulson J. C., Hill R. L. Purification to homogeneity of a β-galactoside α - 3 sialyltransferase and partial purification of an α-N-acetygalactosaminide α2 - 6 sialyltransferase from porcine submaxillary glands. J. Biol. Chem. 1979; 254: 4434
  • Bernacki R. J., Porter C. W. Biochemical and ultrastructural studies of ectoglycosyltransferase systems of murine L1210 leukemic cells. J. Supramol. Struct. 1978; 8: 139
  • Kessel D., Chou T., Allen J. Some properties of sialyltransferase in plasma and lymphocytes of patients with chronic lymphocytic leukemia. Eur. J. Biochem. 1978; 82: 535
  • Scialla S. J., Speckart S. F., Haut M. J., Kimball D. B. Alterations in platelet surface sialyltransferase activity and platelet aggregation in a group of cancer patients with a high incidence of thrombosis. Cancer Res. 1979; 39: 2031
  • Podolsky D. K., Weiser M. M., Isselbacher K. J. Inhibition of growth of transformed cells and tumors by an endogenous acceptor of galactosyltransferase. Proc. Natl. Acad. Sci. U.S.A. 1978; 75: 4426
  • Ingraham H. A., Alhadeff J. A. Characterization of sialyltransferase in non-cancerous and neo-plastic human liver tissue. J. Natl. Cancer Inst. 1978; 61: 1371
  • Ip C., Dao T. L. Increase in serum and tissue glycosyltransferases and glycosidases in tumor-bearing rats. Cancer Res. 1977; 37: 3442
  • Klohs W. D., Bernacki R. J., Korytnyk W. Effects of nucleotides and nucleotide-analogs on human serum sialyltransferase. Cancer Res. 1979; 39: 1231
  • Carlson D. M., Jourdian G. W. Rat mammary gland sialyl-lactose. Methods in Enzymology, E. F. Neufeld, V. Ginsburg. Academic Press, New York 1966; vol. 8: 358
  • Schenkel-Brunner H., Chester M. A., Watkins W. M. α-L-fucosyltransferases in human serum from donors of different ABo, secretor and Lewis blood-group phenotypes. Eur. J. Biochem. 1972; 30: 269
  • Chester M. A., Yates A. D., Watkins W. M. Phenyl-β-D-galactopyranoside as an acceptor substrate for the blood group-H gene-associated guanosine diphosphate L-fucose: β-D-galactoside α-2-L-fucosyltransferase. Eur. J. Biochem. 1976; 69: 583
  • Munro J. R., Schachter H. The presence of two GDP-L-fucose glycoprotein fucosyltransferases in human serum. Arch. Biochem, Biophys. 1973; 156: 534
  • Jabbal I., Schachter H. Pork liver guanosine diphosphate-L-fucose glycoprotein fucosyltransferases. J. Biol. Chem. 1971; 246: 5154
  • Khilanani P., Chou T.-H., Lomen P. L., Kessel D. Variation of levels of plasma GDP-L-fucose:β-D-galactosyl α-2-L-fucosyltransferase in acute adult leukemia. Cancer Res. 1977; 37: 2557
  • Khilanani P., Chou T-H., Kessel D. Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as an index of bone marrow hyperplasia after chemotherapy. Cancer Res. 1978; 38: 181
  • Bauer C. H., Reutter W. G., Erhart K. P., Köttgen T., Gerok W. Decrease of human fucosyl-transferase as an indicator of successful tumor therapy. Science 1979; 201: 1232
  • Nilsson B., Nordén N. E., Svensson S. Structural studies on the carbogydrate portion of futuin. J. Biol. Chem. 1979; 254: 545
  • Kessel D., Ratanatharathron V., Chou T-H. Electrofocusing patterns of fucosyltransferases in plasma of patients with neoplastic disease. Cancer Res. 1979; 39: 3377
  • Kuhns W. J., Oliver R. T. D., Watkins W. M. Alterations in serum and tissue glycosyltransferase enzymes in acute leukemia. Blood 1976; 48: 997
  • Chou T-H., Murphy C., Kessel D. Selective inhibition of a plasma fucosyltransferase by N-ethylmaleimide. Biochem. Biophys. Res. commun. 1977; 74: 1001
  • Kessel D. Human serum fucosyltransferases and tumor therapy. Science 1979; 204: 647
  • Bauer C. H. Human serum fucosyltransferases and tumor therapy. Science 1979; 204: 647
  • Wagner R. R., Cynkin M. A. Glycoprotein metabolism: a UDP-galactose: glycoprotein galactosyltransferase of rat serum. Biochem. Biophys. Res. Commun. 1971; 45: 57
  • Kim Y. S., Perdomo J., Whitehead J. S. Glycosyltransferases in human blood. I. Galactosyltransferase in human serum and erythrocyte membrane. J. Clin. Invest. 1972; 51: 2024
  • Nelson J. D., Jato-Rodriguez J. T., Mookerjea S. Occurrence of soluble glycosyltransferaes in human amniotic fluid. Biochem. Biophys. Res. Commun. 1973; 55: 530
  • Ko G. K. W., Raghupathy E., McKean C. M. UDP-galactose: glycoprotein galactosyltransferase and UDP-N-acetylgalactosamine: protein N-acetylgalactosaminyltransferase activities of human cerebrospinal fluid. Can. J. Biochem. 1973; 51: 1460
  • Kim Y. S., Perdomo J., Whitehead J. S., Curtis K. J. Glycosyltransferases in human blood. II. Study of serum galactosyltransferases and N-acetylgalactosaminyltransferase in patients with liver disease. J. Clin. Invest. 1972
  • Bhattacharya M., Chatterjee S. K., Barlow J. J. Correlation of UDP-galactose: glycoprotein galactosyltransferase levels in the sera with the clinical status of ovarian cancer patients. Cancer Lett. 1978; 5: 239
  • Chatterjee S. K., Bhattacharya M., Barlow J. J. Correlation of UDP-galactose glycoprotein galactosyltransferase levels in the sera with the clinical status of ovarian cancer patients. Cancer Lett. 1978; 5: 239
  • Pohl A., Moser K. Ein Isoenzym der Galactosyltransferase als Tumor Spezifisches Diagnosticum. Verh. Dtsch. Ges. Inn. Med. 1978; 84: 594
  • Liu C-K., Schmied R., Waxman S. Abnormal glycosyltransferases in human hepatoma. Proc. Amer. Assoc. Cancer Res. 1979; 20: 285
  • Fitzgerald D. K., brodbeck V., Kiyosawa I., Mawal R., Colvin B., Ebner K. E. α-Lactalbumin and the lactose synthetase reaction. J. Biol. Chem. 1970; 245: 2103
  • Trayer I. P., Hill R. L. The purification and properties of the A protein of lactose synthetase. J. Biol. Chem. 1971; 246: 6666
  • Powell J. T., Brew K. The preparation and characterization of two forms of bovine galactosyltransferase. Eur. J. Biochem. 1974; 48: 217
  • Ivatt R. J., Rosemeyer M. A. Lactose synthetase. The isolation and characterization of the protein-protein complex. Eur. J. Biochem. 1976; 64: 233
  • Verbert A., Cacan R., Montrevil J. Ectogalactosyltransferase. Presence of enzyme and acceptors on the rat lymphocyte cell surface. Eur. J. Biochem. 1976; 70: 49
  • Berger E. G., Kozdrowski I. Permanent mixed-field polyagglutinable erythrocytes lack galactosyltransferase activity. FEBS Lett. 1978; 93: 105
  • Berger E. G., Kozdrowski I., Weiser M. M., Van den Eijnden H. H., Schiphorst W. E. C. M. Human serum galactosyltransferase: distinction, separation and product indentification of two galactosyltransferase activities. Eur. J. Biochem. 1978; 90: 213
  • Capel I. D., Jenner M., Pinnock M. H., Dorrell H. M., Payne D. C., Williams D. C. Correlation between tumour size, metastatic spread, and galactosyltransferase activity on cyclophosphamide-treated mice bearing the Lewis lung carcinoma. Oncology 1979; 36: 242
  • Plotkin G. M., Wides R. J., Gilbert S. L., Wolf G., Hagen I. K. Galactosyltransferase activity in human transitional cell carcinoma lines and in benign and neoplastic human bladder epithelium. Cancer Res. 1979; 39: 3856
  • Podolsky D. K., Weiser M. M., Westwood J. C., Gammon M. Cancer-associated serum galacto-sytransferase activity. Demonstration in an animal model system. J. Biol. Chem. 1977; 252: 1807
  • Podolsky D. K., Weiser M. M. Detection, purification and characterization of a human cancer-associated galactosyltransferase acceptor. Biochem. J. 1979; 178: 279
  • Spiro R. G. Studies on fetuin, a glycoprotein of fetal serum: I. Isolation, chemical composition and physico-chemical properties. J. Biol. Chem. 1960; 235: 2860
  • Nilsson B., Nordén N. E., Svensson S. Structural studies on the carbohydrate portion of fetuin. J. Biol. Chem. 1979; 254: 4545
  • Weiser M. M. Intestinal epithelial cell surface membrane glycoprotein synthesis: II. glycosyltransferases and endogenous acceptors of the undifferentiated cell surface membrane. J. Biol. Chem. 1973; 248: 2542
  • Podolsky D. K., Weiser M. M. Purification of galactosyltransferase “isoenzymes” I and II: Comparison of cancer-associated and normal galactosyltransferase activities. J. Biol. Chem. 1979; 254: 3983
  • Andrews P. Purification of lactose synthetase, a protein from human milk and demonstration of its interaction with α-lactalbumin. FEBS Lett. 1970; 9: 297
  • Magee S. C., Mawal R., Ebner K. E. Multiple forms of galactosyltransferase from bovine milk. Biochemistry 1974; 13: 99
  • Barker R., Olsen K. W., Shaper J., Hill R. L. Agarose derivatives of uridine diphosphate and N-acetylglucosamine for the purification of a galactosyltransferase. J. Biol. Chem. 1972; 247: 7135
  • Prieels J-P., Maes E., Dolmans M., Leonis J. Heterogeneity of human milk β(1–4)-D-galactosyl-transferase. Eur. J. Biochem. 1975; 60: 525
  • Lehman E. D., Hudson B. G., Ebner K. E. Studies on the carbohydrate structure of bovine milk galactosyltransferase. FEBS Lett. 1975; 54: 65
  • Reitman M., Trowbridge I., Hyman R., Kornfeld S. Pea lectin resistant mouse lymphoma cell lines are defective in fucose metabolism. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1980; 39: 2116
  • Longmore G., Schachter H. Product identification and substrate specificity of pork liver GDP-L-Fuc:β-N-acetylglucosaminide (Fuc-Asn-linked GlcNAc) α6-fucosyltransferase. Fed. Proc. Fed. Am. Soc. Exp. Biol. 1980; 39: 2002
  • Kuhns W. J., Oliver R. T., Watkins W. M., Greenwell P. Leukemia-induced alterations of serum glycosyltransferase enzymes. Cancer Res. 1980; 40: 268
  • Henderson M., Kessel D. Alterations in plasma sialyltransferase levels in patients with neoplastic disease. Cancer (Philadelphia) 1977; 39: 1129

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.