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Research Article

Quantitation of Serum Immunoglobulins

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Pages 103-170 | Published online: 27 Sep 2008

References

  • Heidelberger M., Kendall F. E. Quantitative studies on the precipitin reaction. The determination of small amounts of a specific polysaccharide. J. Exp. Med. 1932; 55: 555
  • Heremans J. F., Masson P. L. Specific analysis of immunoglobulins. Techniques and clinical value. Clin. Chem. 1973; 19: 294
  • Ritzmann S. E., Daniels J. C. Serum Protein Abnormalities. Diagnostic and Clinical Aspects. Little, Brown, Boston 1975
  • Buffone G. J. Assay of plasma proteins by immunochemical technique. Clinical Immunochemistry. Chemical and Cellular Bases and Applications in Disease, S. Natelson, A. J. Pesce, A. A. Dietz. Am. Assoc. Clin. Chem., Washington, DC 1978; 357
  • Ritchie R. F. Automated Immunoanalysis. Marcel Dekker, New York 1978, Parts 1 and II
  • Nakamura R. M., Dito W. R., Tucker E. S., III. Immunoassays in the Clinical Laboratory. Alan R. Liss, New York 1979
  • Libby R. L. A new and rapid quantitative technique for the determination of the potency of Types I and II antipneumococcal serum. J. Immunol. 1938; 34: 269
  • Pope C. G., Healey M. A photo-electric study of reactions between diphtheria toxin and antitoxin. Br. J. Exp. Pathol 1938; 19: 397
  • Boyden A., Bolton E., Gemeroy D. Precipitin testing with special reference to the photoelectric measurement of turbidity. J. Immunol. 1947; 57: 211
  • Gitlin D., Edelhoch H. A study of the reaction between human serum albumin and its homologous equine antibody through the medium of light scattering. J. Immunol 1951; 66: 67
  • Goldberg R. J., Campbell D. H. The light-scattering properties of an antigen-antibody reaction. J. Immunol. 1951; 66: 79
  • Marrack J. R., Grant R. A. The interaction of antigens and antibodies in the presence of low concentrations of salt. Br. J. Exp. Pathol 1953; 34: 263
  • Marrack J. R., Richards C. B. Light-scattering studies of the formation of aggregates in mixtures of antigen and antibody. Immunology 1971; 20: 1019
  • Ritchie R. F. A simple, direct, and sensitive technique for measurement of specific protein in dilute solution. J. Lab. Clin. Med. 1967; 70: 512
  • Kahan J., Sundblad L. Automated immunochemical determination of β-lipoproteins. Automation in Analytical Chemistry. Mediad, New York 1967; Vol. II: 361
  • Eckman I., Robbins J. B., van den Hamer C. J. A., Lentz J., Scheinberg I. H. Automation of a quantitative immunochemical microanalysis of human serum transferrin: a model system. Clin. Chem. 1970; 16: 558
  • Killingsworth L. M., Savory J., Trague P. O. Automated immunoprecipitin technique for analysis of the third component of complement (C'3) in human serum. Clin. Chem. 1971; 17: 374
  • Killingsworth L. M., Savory J. Automated immunochemical procedures for measurement of immunoglobulins IgG, IgA, and IgM in human serum. Clin. Chem. 1971; 17: 936
  • Larsen C., Orenstein P., Ritchie R. F. An automated method for quantitation of proteins in body fluids. Advances in Automated Analysis. Thurman Assoc. 1971; Vol. I: 101
  • Markowitz H., Tschida A. R. Automated quantitative immunochemical analysis of human immunoglobulins. Clin. Chem. 1972; 18: 1364
  • Savory J., Heintges M. G., Killingsworth L. M., Potter I. M. Manual and automated determination of immunoglobulins in unconcentrated cerebrospinal fluid. Clin. Chem. 1972; 18: 37
  • Laffln R. J. A simple immunologic method for the quantitation of immunoglobulin G in human cerebrospinal fluid. J. Lab. Clin. Med. 1970; 76: 816
  • Hellsing K. Influence of polymer on the antigen-antibody reaction in a continuous flow system. Advances in Automated Analysis. Technicon International Congress, Mediad, New York 1972; 17
  • Ritchie R. F., Alper C. A., Graves J., Pearson N., Larson C. Automated quantitation of proteins in serum and other biologic fluids. Am. J. Clin. Pathol 1973; 59: 151
  • Lizana J., Hellsing K. Polymer enhancement of automated immunological nephelometric analysis, as illustrated by determination of urinary albumin. Clin. Chem. 1974; 20: 415
  • Larsen C., Gorman J. M., Becker A. M. Automated immunoprecipitin for proteins in body fluids. Further advances. Advances in Automated Analysis. Technicon International Congress, Mediad, New York 1972; 21
  • Lizana J., Jansson L., Hellsing K. Electronic timing of a high-speed immunonephelometric continuous-flow system. Clin. Chem. 1975; 21: 762
  • Williams V. R., Williams H. B. Basic Physical Chemistry for the Life Sciences. W. H. Freeman, San Francisco 1967; 302
  • Ritchie R. F. Automated immunoprecipitation analysis of serum proteins. The Plasma Proteins2nd ed., F. W. Putnam. Academic Press, New York 1975; Vol. 2: 375
  • Ritchie R. F. Evaluation of antibody preparations for the AIP system. Advances in Automated Analysis. Technicon International Congress, Mediad, New York 1972; 59
  • Ward A. M. IgM. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 239
  • Alper C. A., Ritchie R. F. Comparison of immunochemical techniques. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 139
  • Killingsworth L. M., Savory J. Manual nephelometric methods for immunochemical determination of immunoglobulins IgG, IgA and IgM in human serum. Clin. Chem. 1972; 18: 335
  • Killingsworth L. M., Buffone G. J., Sonawane M., Lunsford G. C. Optimizing nephelometric measurement of specific serum proteins: evaluation of three diluents. Clin. Chem. 1974; 20: 1548
  • Walker W. H. C., Gauldie J. Automated determination of immunoglobulins. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 203
  • Watson A., Young P., Davidson J. F., Fleck A. An assessment of an automated immunoprecipitin technique for the measurement of immunoglobulins G, A and M. Med. Lab. Tech. 1974; 31: 63
  • Marcroft J., Newlands I. M. Evaluation of a specific protein analyser. Clin. Chim. Acta 1973; 46: 399
  • Prellwitz W., Kapp S., Müller D. Vergleichende Methoden zur Quantitativ lmmunologischen Bestimmung und Ermittlung von Normbereichen der Immunoglobuline G, A, M, des Haptoglobins und Transferrins mit Hilfe der Automatisierten Immunpräzipitatreaktion. Zeit. Klin. Chem. Klin. Biochem. 1974; 12: 427
  • Buffone G. J., Cross R. E., Savory J., Soodak C. Measurement of laser-induced near front surface light scattering with a parallel fast analyzer system. Anal. Chem. 1974; 46: 2047
  • Buffone G. J., Savory J., Cross R. E. Use of a laser-equipped centrifugal analyzer for kinetic measurement of serum IgG. Clin. Chem. 1974; 20: 1320
  • Sieber A., Gross J. Determination of proteins by laser nephelometry. Prot. Biol. Fluids 1975; 23: 295
  • Deaton C. D., Maxwell K. W., Smith R. S., Creveling R. L. Use of laser nephelometry in the measurement of serum proteins. Clin. Chem. 1976; 22: 1465
  • Caputo M. J. Clinical evaluation of serum-protein quantitation by a new laser nephelometer. Prot. Biol. Fluids 1976; 24: 677
  • Kusnetz J., Mansberg H. P. Optical considerations: nephelometry. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 1
  • Deaton C. D., Maxwell K. W., Smith R. S. Laser nephelometry. Automated Immuno-analysis, R. F. Ritchie. Marcel Dekker, New York 1978; 375
  • Baruth B., Caputo M. J., Deicher H., Leyssem H. Quantitative bestimmung von serum-proteinen mit einem neuen laser- nephelometer. J. Clin. Chem. Clin. Biochem. 1978; 16: 397
  • Whicher J. T., Perry D. E., Hobbs J. R. An evaluation of the Hyland laser nephelometer PDQ system for the measurement of immunoglobulins. Ann. Clin. Biochem. 1978; 15: 77
  • Buffone G. J., Lewis S. A. Manual immunochemical nephelometric assays for serum immunoglobulins, IgG, IgA and IgM. Clin. Chem. 1979; 25: 1009
  • Ellis D., Buffone G. J. New approach to evaluation of proteinuric states. Clin. Chem. 1977; 23: 666
  • Walsh R. L., Coles M. E., Geary T. D. Evaluation of two commercially available laser nephelometers and their recommended methods for measurement of serum immunoglobulin G. Clin. Chem. 1979; 25: 151
  • Alexander R. L., Jr. Comparison of radial immunodiffusion and laser nephelometry for quantitating some serum proteins. Clin. Chem. 1980; 26: 314
  • Joseph J. C., Bermes E. W. Comparison of protein values in cerebrospinal fluid by nephelometry and radial immunodiffusion. Ann. Clin. Lab. Set 1979; 9: 408
  • Virella G., Fudenberg H. H. Comparison of immunoglobulin determinations in pathological sera by radial immunodiffusion and laser nephelometry. Clin. Chem. 1977; 23: 1925
  • Schliep G., Felgenhauer K. Rapid determination of proteins in serum and cerebrospinal fluid by laser-nephelometry. J. Clin. Chem. Clin. Biochem. 1978; 16: 631
  • Jones C. E., Rousseau R. J., Maxwell K. W. Quantitation of rheumatoid factor activity by nephelometry. Am. J. Clin. Pathol 1979; 72: 432
  • Braver R. M., Salkie M. L. A comparative study of three approaches to the routine quantitation of human serum proteins. Clin. Biochem. 1978; 11: 112
  • Hawkins J. D. Some studies on the precipitin reaction using a turbidimetric method. Immunology 1964; 7: 229
  • Tengerdy R. P. Reaction kinetic studies of the antigen antibody reaction. J. Immunol. 1967; 99: 126
  • Tiffany T. O., Parella J. M., Johnson W. F., Burtis C. A. Specific protein analysis by light-scatter measurement with a miniature centrifugal fast analyzer. Clin. Chem. 1974; 20: 1055
  • Buffone G. J., Savory J., Cross R. E., Hammond J. E. Evaluation of kinetic light scattering as an approach to the measurement of specific proteins with the centrifugal analyzer. I. Methodology. Clin. Chem. 1975; 21: 1731
  • Buffone G. J., Savory J., Hermans J. Evaluation of kinetic light scattering as an approach to the measurement of specific proteins with the centrifugal analyzer. II. Theoretical considerations. Clin. Chem. 1975; 21: 1735
  • Savory J., Buffone G. J., Reich R. Kinetics of the IgG-anti-IgG reaction, as evaluated by conventional and stopped-flow nephelometry. Clin. Chem. 1974; 20: 1071
  • Sternberg J. C. A rate nephelometer for measuring specific proteins by immunoprecipitin reactions. Clin. Chem. 1977; 23: 1456
  • Deaton C. D., Lillig J., Derry C. The immunochemical evaluation of an automated rate nephelometer for specific protein profiling. Clin. Chem. 1980; 26: 1032
  • Anderson R. J., Sternberg J. C. A rate nephelometer for immunoprecipitin measurement of specific serum proteins. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 409
  • Burdash N., Ponzio A., Papadopoulos V., Loadholt C. B. Comparison of methodologies for immunoglobulin quantitation. Clin. Chem. 1981; 27: 345
  • Derry C., Deaton C. D. The influence of analytical variables on proficiency survey results for immunoglobulins G, A and M. Clin. Chem. 1980; 26: 1013
  • Nishi H. H., Young D. S. A flexible reaction rate analytical system for the rapid determination of IgA, IgG and IgM concentrations. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 353
  • Finley P. R., Hicks M. J., Williams R. J., Hinlicky J., Lichti D. A. Rate nephelometric measurement of rheumatoid factor in serum. Clin. Chem. 1979; 25: 1909
  • Anderson N. G. Basic principles of fast analyzers. Am. J. Clin. Pathol. 1970; 53: 778
  • Burtis C. A., Mailen J. C., Johnson W. F., Scott C. D., Tiffany T. O., Anderson N. G. Development of a miniature fast analyzer. Clin. Chem. 1972; 18: 753
  • Buffone G. J., Heintges M. G., Savory J., Killingsworth L. The kinetic nephelometric measurement of IgG and albumin in serum and CSF using a laser-modified Aminco Rotochem centrifugal fast analyzer. Clin. Chem. 1975; 21: 943
  • Finley P. R., Williams R. J., Byers J. M., III. Immunochemical determination of human immunoglobulins with a centrifugal analyzer. Clin. Chem. 1976; 22: 1037
  • Finley P. R., Williams R. J., Lichti D. A., Griffith F., Thies A. C. Immunochemical determination of human immunoglobulins: use of kinetic turbidimetry and a 36-place centrifugal analyzer. Clin. Chem. 1979; 25: 526
  • Blom M., Hjorne N. Immunochemical determination of a serum albumin with a centrifugal analyzer. Clin. Chem. 1975; 21: 195
  • Blom M., Hjorne N. Profile analysis of blood proteins with a centrifugal analyzer. Clin. Chem. 1976; 22: 657
  • Shumate S. E., II, Scott C. D. Centrifugal system for affinity chromatography with eluate monitoring. Clin.- Chem. 1976; 22: 1493
  • Dito W. R. Rapid immunonephelometric quantitation of eleven serum proteins by centrifugal fast analyzer. Am. J. Clin. Pathol 1979; 71: 301
  • Hills L. P., Tiffany T. O. Comparison of turbidimetnc and light-scattering measurements of immunoglobulins by use oi a centrifugal analyzer with absorbance and fluorescence/light scattering optics. Clin. Chem. 1980; 26: 1459
  • Leitz V. M., Fitzgerald D. E., Adolf P. K. Rapid quantitation of human serum immunoglobulins on the GEMENI centrifugal analyzer. Clin. Chem. 1980; 26: 1031
  • Law W. T., Matteo M., Ertingshausen G. Automation of specific protein analyses on the Centrifichem analyzer. Clin. Chem. 1980; 26: 1032
  • Savory J., Buffone G. J. The measurement of specific proteins by fast analysis techniques. Automated Immunoanalysis, R. F. Ritchie. Marcel Dekker, New York 1978; 335
  • Dito W. R. Immunoassays and the centrifugal fast analyzer. Immunoassays in the Clinical Laboratory, R. M. Nakamura, W. R. Dito, E. S. Tucker, III. Alan R. Liss, New York 1979; 67
  • Yalow R. S., Berson S. A. Immunoassay of endogenous plasma insulin in man. J. Clin. Invest. 1960; 39: 1157
  • Weiler R. J., Hofstra D., Szentivanyi A., Blaisdell R., Talmage D. W. The inhibition of labelled antigen precipitation as a measure of serum γ-globulin. J. Immunol. 1960; 85: 130
  • Fahey J. L., Lawrence M. E. Quantitative determination of 6.6s γ-globulins, B 2A-globulins and -γ1-macroglobulins in human serum. J. Immunol. 1963; 91: 597
  • Morgan C. R., Lazarow A. Immunoassay of insulin using a two-antibody system. Proc. Soc. Exp. Biol. Med. 1962; 110: 29
  • Morgan C. R., Lazarow A. Immunoassay of insulin: two antibody system. Plasma insulin levels of normal, subdiabetic and diabetic rats. Diabetes 1963; 12: 115
  • Gleich G. J., Averbeck A. K., Swediund H. A. Measurement of IgE in normal and allergic serum by radioimmunoassay. J. Lab. Clin. Med. 1971; 77: 690
  • Waldmann T. A., Polmar S. H., Balestra S. T., Jost M. C., Bruce R. M., Terry W. D. Immunoglobulin E in immunologic deficiency diseases. II. Serum IgE concentration of patients with acquired hypogammaglobulinemia, thymoma and hypogamma globulinemia, Myotonic Dystrophy, Intestinal Lymphangiectasia and Wiskott-Aldrich syndrome. J. Immunol 1972; 109: 304
  • Waldmann T. A., Broder S., Blaese R. M., Durm M., Blackman M., Stober W. Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinemia. Lancet 1974; 2: 609
  • Broder S., Humphrey R., Durm M., Blackman M., Meade B., Goldman C., Strober W., Waldmann T. Impaired synthesis of polyclonal (non-paraprotein) immunoglobulins by circulating lymphocytes from patients with multiple myeloma. New Engl. J. Med. 1975; 293: 887
  • Broder S., Edelson R. L., Lutzner M. A., Nelson D. L., MacDermott R. P., Durm M. E., Goldman C. K., Meade B. D., Waldmann T. A. The Sezary syndrome. A malignant profllera-tion of helper T cells. J. Clin. Invest. 1976; 58: 1297
  • Macy E., Stevens R. H. A restricted component of T cell help in pokeweed mitogen stimulated human peripheral blood cell cultures. J. Immunol 1980; 124: 752
  • Wide L., Bennich H., Johansson S. G. O. Diagnosis of allergy by an in-vitro test for allergen antibodies. Lancet. 1967; 2: 1105
  • Adkinson N. F., Jr. Measurement of total serum immunoglobulin E and allergen-specific immunoglobulin E antibody. Manual of Clinical Immunology2nd ed., N. R. Rose, H. Friedman. Am. Soc. Micro., Washington, DC 1980; 107
  • Rose N. R., Friedman H. Manual of Clinical Immunology2nd ed. Am. Soc. Microbiol., Washington, DC 1980; 41
  • Gleich G. J., Dunnette S. L. Comparison of procedures for measurement of IgE protein in serum and secretions. J. Allergy Clin. Immunol 1977; 59: 377
  • Waller S. J., Taylor R. P., Andrews B. S. A polyethylene glycol radioimmunoprecipitation assay for human immunoglobulin G. J. Immunol. Methods 1979; 30: 171
  • Petrie G. F. A specific precipitin reaction associated with the growth on agar plates of meningococcus, pneumococcus and B. dysenteriae (Shiga). Br. J. Exp. Pathol. 1932; 13: 380
  • Ouchterlony O. In vitro method for testing the toxin-producing capacity of diphtheria bacteria. Acta Pathol. Micro. Scand. 1949; 26: 516
  • Feinberg J. G. Identification, discrimination and quantification in Ouchterlony gel plates. Int. Arch. Allergy Appl. Immunol. 1957; 11: 129
  • Hayward B. J., Augustin R. Quantitative gel diffusion methods for assay of antigens and antibodies. Int. Arch. Allergy 1957; 11: 192
  • Crowle A. J. Four modifications of the micro agar diffusion precipitin test. J. Lab. Clin. Med. 1960; 55: 593
  • Mancini G., Vaerraan J.-P., Carbonara A. O., Heremans J. F. A single-radial-diffusion method for the immunological quantitation of proteins. Prot. Biol. Fluids 1964; 11: 370
  • Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965; 2: 235
  • Fahey J. L., McKelvey E. M. Quantitative determination of serum immunoglobulins in antibody-agar plates. J. Immunol 1965; 94: 84
  • Hanson L. A., Holmgren J., Wadsworth C. A radial immuno-gel filtration method for characterization and quantitation of macromolecules. Int. Arch. Allergy 1971; 40: 806
  • Berne B. H. Differing methodology and equations used in quantitating immunoglobulins by radial immunodiffusion – a comparative evaluation of reported and commercial techniques. Clin. Chem. 1974; 20: 61
  • Jackson A. L., Davis N. C. Quantitation of immunoglobulins. Manual of Clinical Immunology2nd ed., N. R. Rose, H. Friedman. Am. Soc. Microbiol., Washington, DC 1980; 109
  • Stiehm E. R. Radial diffusion technique for the quantitative estimation of precipitating antibody. J. Lab. Clin. Med. 1967; 70: 528
  • Daniels J. C., Vyvial T. M., Levin W. C., Ritzmann S. E. Methodologic differences in values for M-proteins in serum, as measured by three techniques. Clin. Chem. 1975; 21: 243
  • Gilliland B. C. Immunologic quantitation of serum immunoglobulins. Am. J. Clin. Pathol 1977; 68: 664
  • Gilliland B. C., Mannik M. Immunologic quantitation of proteins in serum, urine and other body fluids. Laboratory Diagnosis of Immunologic Disorders, G. N. Vyas, D. P. Stites, G. Brecher. Grune & Stratton, New York 1975; 13
  • Kalf T. M. W. Quantitative determination of serum immunoglobulin levels by single radial immunodiffusion. Clin. Biochem. 1970; 3: 91
  • Hosty T. A., Hollenbeck M., Shane S. Intercomparison of results obtained with five commercial diffusion plates supplied for quantitation of immunoglobulins. Clin. Chem. 1973; 19: 524
  • de Bruyn A. M., Klein F. The validity of the radial immunodiffusion method for the quantitative determination of human IgM. Evaluation of a modified method. J. Immunol Methods 1976; 11: 311
  • Perry J. J., Bray P. F., Hackett T. N., Jr. Comparison of electroimmunodiffusion and radial immunodiffusion for measurement of IgG in the laboratory diagnosis of multiple sclerosis. Clin. Chem. 1974; 20: 1441
  • Alpert E., Monroe M., Schur P. A method for increasing the sensitivity of radial-immuno-diffusion assay. Lancet 1970; 1: 1120
  • Simmons P. Quantitation of plasma proteins in low concentrations using RID. Clin. Chim. Acta 1971; 35: 53
  • Rowe D. S. Radioactive single radial diffusion: a method for increasing the sensitivity of immunochemical quantification of proteins in agar gel. Bull. WHO 1969; 40: 613
  • Arbesman C. E., Ito K. A new method for measuring IgE. J. Allergy 1971; 47: 85
  • Jalanti R., Henney C. S. Studies on single radial immunodiffusion techniques for the quantitation of antigen and antibody. J. Immunol Meth. 1972; 1: 123
  • Ressler N. Electrophoresis of serum protein antigens in an antibody-containing buffer. Clin. Chim. Acta 1960; 5: 359
  • Laurell C.-B. Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal. Biochem. 1966; 15: 45
  • Laurell C.-B. Quantitative estimation of proteins by electrophoresis in antibody-containing agarose gel. Prot. Biol. Fluids 1966; 14: 499
  • Hartley T. F., Merrill D. A., Claman H. N. Quantitation on immunoglobulins in cerebrospinal fluids. Arch. Neurol. 1966; 15: 472
  • Merrill D. A., Hartley T. F., Claman H. N. Electroimmunodiffusion (EID): a simple, rapid method for quantitation of immunoglobulins in dilute biological fluids. J. Lab. Clin. Med. 1967; 69: 151
  • Lopez M., Tsu T., Hyslop N. E., Jr. Studies of electroimmunodiffusion: immunochemical quantitation of proteins in dilute solutions. Immunochemistry 1969; 6: 513
  • Weeke B. Quantitative estimation of human immunoglobulins following carbamylation by electrophoresis in antibody-containing agarose. Scand. J. Clin. Lab. Invest. 1968; 22: 107
  • Raisys V. A., Arvan D. A. Determination of proteins in biological fluids by electroimmunodiffusion and two-directional Immunoelectrophoresis. Clin. Chem. 1971; 17: 745
  • Bjerrum O. J., Ingild A., Lowenstein H., Weeke B. Quantitation of human IgG by rocket Immunoelectrophoresis at pH 5 by use of carbamylated antibodies. A routine laboratory method. Clin. Chim. Acta. 1973; 46: 373
  • Axelson N. H., Kroll J., Weeke B. A Manual of Quantitative Immunoelectrophoresis. Scand. J. Immunol. 1973; 2: 1, (Suppl)
  • Gill C. W., Fischer C. L., Holleman C. L. Rapid method for protein quantitation of electroimmunodiffusion. Clin. Chem. 1971; 17: 501
  • Schuller E., Lefevre M., Tömpe L. Electroimmunodiffusion of a2M, IgA and IgM in nanogram quantities with a hydroxyethylcellulose – agarose gel: application to unconcentrated CSF. Clin. Chim. Acta. 1972; 42: 5
  • Bjerrum O. J., Ingild A., Lowenstein H., Weeke B. Carbamylated antibodies used for quantitation of human IgG. A routine method, in A Manual of Quantitative Immunoelectrophoresis, Axelson N. H., Kroll J., Weeke B., Ed. Scand. J. Immunol. 1973; 2(Suppl. 1)149
  • Kindmark C.-O., Thorell J. I. Quantitative determination of individual serum proteins by radio-electroimmuno and use of 125I-labelled antibodies (application to C-reactive protein). Scand. J. Clin. Lab Invest. 1972; 29(Suppl. 124)49
  • Verbruggen R. Quantitative immunoelectrophoretic methods: a literature survey. Clin. Chem. 1975; 21: 5
  • Salvaggio J. E., Arquembourg P. C., Sylvester G. A. A comparison of the sensitivity of electroimmunodiffusion and single radial diffusion in quantitation of immunoglobulins in dilute solution. J. Allergy 1970; 46: 326
  • Laurell C.-B. Electroimmuno assay. Scand. J. Clin Lab. Invest. 1972; 29(Suppl. 124)21
  • Ganrot K., Laurell C.-B. Measurement of IgG and albumin content of cerebrospinal fluid and its interpretation. Clin. Chem. 1974; 20: 571
  • Ganrot-Norlin K. Relative concentrations of albumin and IgG in cerebrospinal fluid in health and in acute meningitis. Scand, J. Infect. Dis. 1978; 10: 57
  • Cart K., Niall H. D., Tregear G. W. Solid-phase radioimmunoassay of human growth hormone. Biochem. J. 1966; 100: 13C
  • Wide L., Porath J. Radioimmunoassay of proteins with the use of Sephadex-coupled antibodies. Biochim. Biophys. Acta 1966; 130: 257
  • Cart K., Niall H. D., Tregear G. W. A solid-phase disc radioimmunoassay for human growth hormone. J. Lab. Clin. Med. 1967; 70: 820
  • Cart K., Tregear G. W. Solid-phase radioimmunoassay in antibody-coated tubes. Science 1967; 158: 1570
  • Axen R., Porath J. Chemical coupling of enzymes to cross-linked dextran (“Sephadex”). Nature 1966; 210: 367
  • Axen R., Porath J., Ernback S. Chemical coupling of peptides and proteins to polysaccharides by means of cyanogen halides. Nature 1967; 214: 1302
  • Wide L. Radioimmunoassays employing immunosorbents. Acta Endocrinol., Suppl. 1969; 142: 207
  • Johansson S. G. O., Bennich H., Wide L. A new class of immunoglobulin in human serum. Immunology 1968; 14: 265
  • Mann D., Granger H., Fahey J. L. Use of insoluble antibody for quantitative determination of small amounts of immunoglobulin. J. Immunol. 1969; 102: 618
  • Salmon S. E., Mackey G., Fudenberg H. H. “Sandwich” solid phase radioimmunoassay for the quantitative determination of human immunoglobulins. J. Immunol. 1969; 103: 129
  • Cheng W. C., Talmage D. W. The reaction of immunoglobulin-coated Bentonite and radioiodinated antigen as a basis for antibody detection and antigen binding. J. Immunol. 1969; 103: 1385
  • Bombardier S., Christian C. L. A technique for immunoassay of human IgG. Proc. Soc. Exp. Biol. Med. 1970; 133: 1366
  • Bazaral M., Orgel H. A., Hamburger R. N. IgE levels in normal infants and mothers and an inheritance hypothesis. J. Immunol. 1971; 107: 794
  • Cawley L. P., Goodwin W. L., Moeder M., Dibbern P. Quantitation of serum IgG by solid phase radioimmunoassay. Clin. Chem. 1974; 20: 376
  • Out T. A., van Walbeek H. K., Reerink-Brongers E. E., van der Helm H. J. Radioimmunoassay of immunoglobulins in cerebrospinal fluid. Humoral Immunity in Neurological Diseases, D. Karcher, A. Lowenthal, A. D. Strosberg. Plenum Press, New York 1979; 215
  • Woo J., Floyd M., Longley M. A., Cannon D. C. Radioimmunoassay for immunoglobulin G in serum and urine. Clin. Chem. 1979; 25: 2015
  • Engvall E., Perlmann P. Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochemistry 1971; 8: 871
  • Engvall E., Perlmann P. Enzyme-linked immunosorbent assay, ELISA. III. Quantitation of specific antibodies by enzyme-labelled anti-immunoglobulin in antigen-coated tubes. J. Immunol. 1972; 109: 129
  • van Weemen B. K., Schuurs A. H. W. M. Immunoassay using antigen-enzyme conjugates. Febs. Lett. 1971; 15: 232
  • van Weemen B. K., Schuurs A. H. W. M. Immunoassay using hapten-enzyme conjugates. Febs. Lett. 1972; 24: 77
  • Avrameas S., Guilbert B. Enzyme-immunoassay for the measurement of antigens using peroxidase conjugates. Biochimie 1972; 54: 837
  • Kato K., Hamaguchi J., Fukui H., Ishikawa E. Enzyme-linked immunoassay. II. A simple method for synthesis of the rabbit antibody-β-D-galactosidase complex and its general applicability. J. Biochem. 1975; 78: 423
  • Masseyeff R., Maiolini R., Bouron Y. A method of enzyme immunoassay. Biomedicine 1973; 19: 314
  • Hoffman D. R. Estimation of serum IgE by an enzyme-linked immunosorbent assay (ELISA). J. Allergy Clin. Immunol 1973; 51: 303
  • Panfili P., Grenner G., Wang R. An enzyme immunoassay for human IgE. Clin. Chem. 1980; 26: 1070
  • Hösli P., Avrameas S., Uumann A., Vogt E., Rodrigot M. Quantitative ultramicro-scale immunoenzymic method for measuring Ig antigenic determinants on single cells. Clin. Chem. 1978; 24: 1325
  • Worah D. M., Yeung K.-K., Ward F. E., Carrico R. J. A homogeneous fluorescent immunoassay for human IgM. Clin. Chem. 1980; 26: 986
  • Harris C., Yolken R. H., Krokan H., Hsu I. C. Ultrasensitive enzymatic radioimunoassay: application to detection of cholera toxin and rotavirus. Proc. Natl. Acad. Sci. U.S.A. 1979; 76: 5336
  • Tsang V. C. W., Wilson B. C., Maddison S. E. Kinetic studies of a quantitative single-tube enzyme-linked immunosorbent assay. Clin. Chem. 1980; 26: 1255
  • Wide L. Solid phase antigen-antibody systems. Radioimmunoassay Methods, K. E. Kirkham, W. M. Hunter. Churchill Livingstone, London 1971; 405
  • Avrameas S. Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. Immunochemistry 1969; 6: 43
  • Schuurs A. H. W. M., van Weemen B. K. Enzyme-immunoassay. Clin. Chim. Acta 1977; 81: 1
  • Engvall E., Ruoslahti E. Principles of ELISA and recent applications to the study of molecular interactions. Immunoassays in the Clinical Laboratory, R. M. Nakamura, W. R. Dito, E. S. Tucker, III. Alan R. Liss, New York 1979; 89
  • Nakane P. K., Kawaoi A. Peroxidase-labelled antibody. A new method of conjugation. J. Histochem. Cytochem. 1974; 22: 1084
  • Keydar I., Mesa-Tejada R., Ramanarayanan M., Ohno T., Fenoglio C., Hu R., Spiegelman S. Detection of viral proteins in mouse mammary tumors by immunoperoxidase staining of paraffin sections. Proc. Natl. Acad. Sci. U.S.A. 1978; 75: 1524
  • Kato K., Hamaguchi Y., Fukui H., Ishikawa E. Coupling Fab' fragment of rabbit anti-human IgG antibody to β-D-galactosidase and a highly sensitive immunoassay of human IgG. Febs. Lett. 1975; 56: 370
  • Voller A., Bidwell D., Bartlett A. Enzyme-linked immunosorbent assay. Manual of Clinical Immunology, N. R. Rose, H. Friedman. Am. Soc. Micro., Washington, DC 1980; 45
  • Engvall E., Jonsson K., Perlmann P. Enzyme-linked immunosorbent assay. II. Quantitative assay of protein antigen, immunoglobulin G, by means of enzyme-labelled antigen and antibody-coated tubes. Biochim. Biophys. Acta. 1971; 251: 427
  • Saunders G. C. The art of solid-phase enzyme immunoassay including selected protocols. Immunoassays in the Clinical Laboratory, R. M. Nakamura, W. R. Dito, E. S. Tucker, III. Alan R. Liss, New York 1979; 99
  • Gleich G. J., Jacob G. L., Yunginger J. W., Henderson L. L. Measurement of the absolute levels of IgE antibodies in patients with ragweed hayfever. Effect of immunotherapy on seasonal changes and relationship to IgG antibodies. J. Allergy Clin. Immunol. 1977; 60: 188
  • Coons A. H., Creech H. J., Jones R. N. Immunological properties of an antibody containing a fluorescent group. Proc. Soc. Exp. Biol. Med. 1941; 47: 200
  • Coons A. H., Creech H. J., Jones R. N., Berliner E. The demonstration of pneumococcal antigen in tissues by the use of fluorescent antibody. J. Immunol 1942; 45: 159
  • Coons A. H., Kaplan M. H. Localization of antigen in tissue cells. II. Improvements in a method for the detection of antigen by means of fluorescent antibody. J. Exp. Med. 1950; 91: 1
  • Hlramoto R., Engel K., Pressman D. Tetramethylrhodamine as immunohistochemical fluorescent label in the study of chronic thyroiditis. Proc. Soc. Exp. Biol Med. 1958; 97: 611
  • Riggs J. L., Seiwald R. J., Burckhalter J. H., Downs C. M., Metcalf T. G. Isothiocyanate compounds as fluorescent labelling agents for immune serum. Am. J. Pathol 1958; 34: 1081
  • Toussaint A. J., Anderson R. I. Soluble antigen fluorescent-antibody technique. Appl. Microbiol 1965; 13: 552
  • Toussaint A. J. Improvement of the soluble antigen fluorescent-antibody procedure. Exptl Parasitol 1966; 19: 71
  • Aalberse R. C. Quantitative fluoroimmunoassay. Clin. Chim. Acta 1973; 48: 109
  • van Dalen J. P. R., Knapp W., Ploem J. S. Microfluorometry on antigen-antibody interaction in immunoflouorescence using antigens covalently bound to agarose beads. J. Immunol Methods 1973; 2: 383
  • Knapp W., Ploem J. S. Microfluorometry of antigen-antibody interactions in immunofluorescence using the defined antigen substrate spheres (DASS) system. Sensitivity, specificity and variables of the method. J. Immunol. Methods 1974; 5: 259
  • Decider A. M., Ploem J. S. An immunofluorescence reaction for Schistosoma mansoni using the defined antigen substrate spheres (DASS) system. J. Immunol Methods 1974; 4: 239
  • Camargo M. E., Ferreira A. W. A microscopic immunofluorescence technique with soluble protein antigens fixed to cellulose particles. Int. Arch. Allergy 1970; 39: 292
  • Brandtzaeg P. Evaluation of immunofluorescence with artificial sections of selected antigenicity. Immunology. 1972; 22: 177
  • Capel P. J. A. A quantitative immunofluorescence method based on the covalent coupling of protein to Sepharose beads. J. Immunol Methods 1974; 5: 165
  • Burgett M. W., Fairfield S. J., Monthony J. F. A solid phase fluorescent immunoassay for the quantitation of the C3 component of human complement. Clin. Chim. Acta 1977; 78: 277
  • Burgett M. W., Fairfield S. J., Monthony J. F. A solid phase fluorescent immunoassay for the quantitation of the C4 component of human complement. J. Immunol. Methods 1977; 16: 211
  • Curry R. E., Heitzman H., Riege D. H., Sweet R. H., Simonsen M. G. A systems approach to fluorescent immunoassay: general principles and representative applications. Clin. Chem. 1979; 25: 1591
  • Horan P. K., Schenk E. A., Abraham G. N., Kloszewski E. D. Fluid phase particle fluorescence analysis: rheumatoid factor specificity evaluated by laser flow cytophotometry. Immunoassays in the Clinical Laboratory, R. M. Nakamura, W. R. Dito, E. S. Tucker, III. Alan R. Liss, New York 1979; 185
  • Kameda N., Harte R. A., Deindoerfer F. H. Evaluation of FIAX system for quantitation of serum immunoglobulins G,A and M. Clin. Chem. 1976; 22: 1200
  • Gabriel N. S., Orsini F. M., Jibril A. O., Volini F. I. Evaluation of a rapid immunofluorescence method for the measurement of serum and spinal fluid immunoglobulins. Clin. Chem. 1977; 23: 1155
  • Harte R., Kameda N., Chang J. A simplified fluorescence immunoassay for C4 quantitation in human serum. Clin. Chem. 1978; 24: 1033
  • Chen A. B., Wang R., Rehbinder D. An improved method for the quantitation of serum immunoglobulins G,A and M using the FIAX system. Clin. Chem. 1980; 26: 1071
  • Rock H. S., Burgett M. W., Allen J. D. A new quantitative fluorescence immunoassay for human serum immunoglobulin E. Clin. Chem. 1979; 25: 1078
  • Stevens R. W., Elmendorf D., Gourlay M., Stroebd E., Gaafar H. A. Application of fluoroimmunoassay to cerebrospinal fluid immunoglobulin G and albumin. J. Clin. Microbiol 1979; 10: 346
  • Ullman E. F., Schwarzberg M., Rubenstein K. E. Fluorescent excitation transfer immunoassay. A general method for determination of antigens. J. Biol. Chem. 1976; 251: 4172
  • Ullman E. F. Homogeneous fluorescence immunoassay. Clin. Chem. 1978; 24: 973
  • Rodgers R., Schwarzberg M., Khanna P. L., Chang C.-H., Ullman E. F. A fluorescence quenching immunoassay for IgA. Clin. Chem. 1978; 24: 1033
  • Fisher C. A., Hsu P. C., Daffern G. M., Cobb M. E. Homogeneous fluorescence rate immunoassay for immunoglobulins G, A and M. Clin. Chem. 1980; 26: 987
  • Watson R. A. A., Landon J., Shaw E. J., Smith D. S. Polarisation fluoroimmunoassay of gentamicin. Clin. Chim. Acta 1976; 73: 51
  • Nargessi R. D., Landon J., Smith D. S. Use of antibodies against the label in non-separation non-isotopic immunoassay: “indirect quenching” fluoroimmunoassay of proteins. J. Immunol. Methods 1979; 26: 307
  • Zuk R. F., Rowley G. L., Ullman E. F. Fluorescence protection immunoassay: a new homogeneous assay technique. Clin. Chem. 1979; 25: 1554
  • Nicoli D. F., Briggs J., Elings V. B. Fluorescence immunoassay based on long time correlations of number fluctuations. Proc. Natl. Acad, Sci. U.S.A. 1980; 77: 4904
  • Nakamura R. M. Recent advances in immunochemical fluorescent analytical methods. Immunoassays in the Clinical Laboratory, R. M. Nakamura, W. R. Dito, E. S. Tucker, III. Alan R. Liss, New York 1979; 211
  • Wieder I. Background rejection in fluorescence immunoassay. Immunofluorescence and Related Staining Techniques, W. Knapp, V. Holubar, G. Wick. Elsevier/North Holland, Amsterdam 1978; 67
  • Blanchard G. C., Gardner R. Two immunofluorescent methods compared with a radial immmunodiffusion method for measurement of serum immunoglobulins. Clin. Chem. 1978; 24: 808
  • Haven M. C. Comparison of immunoglobulin methods: turbidimetric, nephelometric, radial immunodiffusion. Clin. Chem. 1980; 26: 1071
  • Cejka J., Mood D. W., Kim C. S. Immunoglobulin concentrations in sera of normal children: quantitation against an international reference preparation. Clin. Chem. 1974; 20: 656
  • Hollander M., Wolfe D. A. Non-Parametric Statistical Methods. John Wiley & Sons, New York 1973
  • Daniels J. C., Deindoerfer F. H. Quantitation of monoclonal IgG and IgA by fluoroimmuno-metric, immunodiffusion and nephelometric techniques. Clin. Chem. 1977; 23: 1154
  • Whicher J. T., Hunt J., Perry D. E., Hobbs J. R., Fifleld R., Keyser J., Kohn J., Riches P., Smith A. M., Thompson R. A., Ward A. M., White P. Method-specific variation in the calibration of a new immunoglobulin standard suitable for use in nephelometric techniques. Clin. Chem. 1978; 24: 531
  • Maddison S. E., Reimer C. B. Normative values of serum immunoglobulins by single radial immunodiffusion: a review. Clin. Chem. 1976; 22: 594
  • Stein S. F., Ward J. H., Woods R. Serum immunoglobulins: methods for the determination of normal values in international units. J. Immunol. Methods 1977; 16: 371
  • Jollitf C., Hergenrader P. The effect of analytical variables on the comparison of radial immunodiffusion and rate nephelometry. Clin. Chem. 1979; 25: 1078
  • Snedecor G. W., Cochran W. G. Statistical Methods6th ed. Iowa State University Press, Ames 1967; 185

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