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Research Article

Ultrastructure, Physiology, and Biochemistry of Bacillus Thuringiensis

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Pages 147-204 | Published online: 25 Sep 2008

References

  • Afrikian E. G. Entomopathogenic Bacteria and Their Significance. Academy of Science, Aremenian SSR, Erevan 1973
  • Akers E., Aronson J. N. Detection on polyacrylamide gels of L-glutamic acid decarboxylase activities from Bacillus thuringiensis. Anal. Biochem. 1971; 39: 535
  • Akune S., Watanabe T., Mukai J., Tsutsui R., Abe K. A toxic protein from insect pathogen Bacillus thuringiensis. Jpn. J. Med. Sci. Biol. 1971; 24: 57
  • Ang B. J., Nickerson K. W. Purification of the protein crystal from Bacillus thuringiensis by zonal gradient centrifugation. Appl. Environ. Microbiol. 1978; 36: 625
  • Angus T. A bacterial toxin paralyzing silkworm larvae. Nature (London) 1954; 173: 545
  • Angus T. Studies of Bacillus spp. pathogenic for silkworm. Progress Report, Forest Biology Division. Canada Department of Science Service 1953; 9(6)
  • Angus T. A. Association of toxicity with protein-crystalline inclusions of Bacillus sotto Ishiwata. Can. J. Microbiol. 1956; 2: 122
  • Angus T., Heimpel A. Inhibition of feeding and blood pH changes in lepidopterous larvae infected with crystal-forming bacteria. Can. Entomol. 1959; 91: 352
  • Aoki K., Chegäsaki Y. Über die Pathogenität der sog. Sotto Bacillen (Ishiwata) bei Seidenrauven. Mitt. Med. Fak. Kais 1915; 13: 419
  • Aronson A. I., Fitz-James P. C. Properties of Bacillus cereusspore coat mutants. J. Bacteriol. 1975; 123: 354
  • Aronson A. I., Fitz-James P. C. Structure and morphogenesis of the bacterial spore coat. Bacteriol. Rev. 1976; 40: 360
  • Aronson A. I., Pandey N. K. Comparative structural and functional aspects of spore coats. Spores VII, O. Chambliss, J. C. Vary. American Society for Microbiology, Washington, D.C. 1978; 54
  • Aronson J. N. Ammonia assimilation and glutamate catabolism by Bacillus thuringiensis. Microbiology 1976, D. Schlessinger. American Society for Microbiology, Washington, D.C. 1976; 444
  • Aronson J. N., Borris D. P., Doerner J. F., Akers E. γ-aminobutyric acid pathway and modified tricarboxylic acid cycle activity during growth and speculation of Bacillus thuringiensis. Appl. Microbiol. 1975; 30: 489
  • Aronson J. N., Bowe P. A., Swafford J. Mesosomes in M-tyrosine-inhibited Bacillus thuringiensis. J. Bacteriol. 1967; 93: 1174
  • Aronson J. N., Doerner J. F., Akers E. W., Borris D. P., Mani M. γ-aminobutyric acid pathway of glutamate metabolism by Bacillus thuringiensis. Spores VI. American Society for Microbiology, Washington, D.C. 1975; 404
  • Aronson J. N., Tillinghast J. A chemical study of the parasporal crystal of Bacillus thuringiensis. Spore Research 1976. Academic Press, New York 1976; 351
  • Aronson J. N., Wermus O. R. Effects of m-tyrosine on growth and sporulation of Bacillus species. J. Bacteriol. 1965; 90: 38
  • Azizbekyan R. R., Belykh R. A., Netyksa E. M., Pogosbekova M. R. Comparative characterization of sporeforming and asporogenic strains of Bacillus thuringiensis. Genetika 1978; 14: 510
  • Bateson J. B., Stainsby G. Analysis of the active principle in the biological insecticide Bacillus thuringiensis Berliner. J. Food Technol. 1970; 5: 403
  • Beaman T. C., Pankratz H. S., Gerhardt P. Paracrystalline sheets reaggregated from solubilized exosporium of Bacillus cereus. J. Bacteriol. 1971; 107: 320
  • Bechtel D. B., Bulla L. A., Jr. Electron microscope study of sporulation and parasporal crystal formation in Bacillus thuringiensis. J. Bacteriol. 1976; 127: 1472
  • Bechtel D. B., Horner H. T. Calcium excretion and deposition during sporogenesis in Physarella oblonga. Calcif. Tissue Res. 1975; 18: 195
  • Berliner E. Über die Schlaffsucht der Mehlmottenroupe. Z. Gesamte. Getreidewes. 1911; 3: 63
  • Berliner E. Über die Schlaffsucht der Mehlmottenraupe (Ephestia kuhniella Zell.) und ihren Erreger Bacillus thuringiensis, n. sp. Z. Angew, Entomol. 1915; 2: 29
  • Berry L. J. Bacterial toxins. CRC Crit. Rev. Toxicol. 1977; 5: 239
  • Bonventre P. F. The nomenclature of microbial toxins: problems and recommendations. Microbial Toxins: A Comprehensive Treatise, S. J. Ajl, et al. Academic Press, New York 1970; Vol. 1
  • Borris D. P., Aronson J. N. Relationship of L-alanine and L-glutamate dehydrogenases of Bacillus thuringiensis. Biochim. Biophys. Acta 1969; 191: 716
  • Bowman H. G., Nilsson-Faye I., Pau K., Rasmuson T., Jr. Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cynthia pupae. Infect. Immun. 1974; 10: 136
  • Bergey's Manual of Determinative Bacteriology, 8th ed., R. E. Buchanan, N. E. Gibbons. Williams & Wilkins, Baltimore 1974
  • Bulla L. A., Jr. Regulation of insect populations by microorganisms. Ann. N.Y. Acad. Sci. 1973; 217
  • Bulla L. A., Jr., Bennett G. A., Shotwell O. L. Physiology of sporeforming bacteria associated with insects. II. Lipids of vegetative cells. J. Bacteriol. 1970; 104: 246
  • Bulla L. A., Jr., Costilow R. N., Sharpe E. S. Biology of Bacillus popilliae. Adv. Appl. Microbiol. 1978; 23: 1
  • Bulla L. A., Jr., Davidson L. I., Kramer K. J., Jones B. L. Purification of the insecticidal toxin from the parasporal crystal of Bacillus thuringiensis subsp. kurstaki. Biochem. Biophys. Res. Commun. 1979; 91: 1123
  • Bulla L. A., Jr., Kramer K. J., Bechtel O. B., Davidson L. I. Entomocidal proteinaceous crystal of Bacillus thuringiensis. Microbiology 1976, D. Schlessinger. American Society for Microbiology, Washington, D.C. 1976; 534
  • Bulla L. A., Jr., Kramer K. J., Davidson L. I. Sporulation-specific protein of Bacillus thuringiensis. Abstracts of the Annual Meeting of the American Society of Microbiology. American Society of Microbiology, Washington, D.C. 1977; 165
  • Bulla L. A., Jr., Kramer K. J., Davidson L. I. Characterization of the entomocidal parasporal crystal of Bacillus thuringiensis. J. Bacteriol. 1977; 130: 375
  • Bulla L. A., Jr., Kramer K. J., Davidson L. I., Schesser J. H., Jones B. L., Cox D. J. Solubilization and characterization of the entomocidal glycoprotein of Bacillus thuringiensis. J. Biol. Chem. 1980, in press
  • Bulla L. A., Jr., Nickerson K. W., Mounts T. L., Iandolo J. J. Biosynthesis of branched-and normal-chain fatty acids during spore germination and outgrowth of Bacillus thuringiensis. Spores VI. American Society for Microbiology, Washington, D.C. 1975; 52
  • Bulla L. A., Jr., Rhodes R. A., St Julian G. Bacteria as insect pathogens. Annu. Rev. Microbiol. 1975; 29: 163
  • Bulla L. A., Jr., St Julian G., Rhodes R. A. Physiology of spore-forming bacteria associated with insects. HI. Radiorespirometry of pyruvate, acetate, succinate, and glutamate oxidation, Can. J. Microbiol. 1971; 17: 1073
  • Bulla L. A., Jr., St Julian G., Rhodes R. A., Hesseltine C. W. Physiology of sporeforming bacteria associated with insects. I. Glucose catabolism in vegetative cells. Can. J. Microbiol. 1970; 16: 243
  • Bulla L. A., Jr., Yousten A. A. Bacterial insecticides. Economic Microbiology, A. H. Rose. Academic Press, New York 1979; Vol. 4: 91
  • Microbial Control of Insects and Mites, H. D. Burges, N. W. Hussey. Academic Press, New York 1971
  • Changchien L.-M., Aronson J. N. Spermidine requirement for Bacillus thuringiensis ribosomes in cell-free phenylalanine incorporation. J. Bacteriol. 1970; 103: 734
  • Cheng Y.-S. E., Aronson A. I. Alterations of spore coat processing and protein turnover in a Bacillus cereus mutant with a defective postexponential intracellular protease. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 1254
  • Chestukhina G. G., Kostina L. I., Zalunin I. A., Kotova T. S., Katrukha S. P., Kuznetsov Y. S., Stepanov V. M. Proteins of Bacillus thuringiensis S-delta-endotoxin crystals. Biokhimiya 1977; 42: 1660
  • Chestukhina G. G., Zalunin I. A., Kostina L. I., Kotova T. S., Katrukha S. P., Lyublinskaya L. A., Stepanov V. M. Proteinases bound to crystals of Bacillus thuringiensis. Biokhimiya 1978; 43: 857
  • Chigaleichik A. G. Chitinase of Bacillus thuringiensis. Mikrobiologiya 1976; 45: 966
  • Conner R. M., Hansen P. A. Effects of valine, leucine, an isoleucine on the growth of Bacillus thuringiensis and related bacteria. J. Invertebr. Pathol. 1967; 9: 12
  • Cooksey K. E. Purification of a protein from Bacillus thuringiensis toxic to larvae of lepidoptera. Biochem. J. 1968; 106: 445
  • Cooksey K. E. The protein crystal toxin of Bacillus thuringiensis: biochemistry and mode of action. Microbial Control of Insects and Mites, H. D. Burges, N. W. Hussey. Academic Press, New York 1971; 247
  • Cooksey K. E., Monninger C., Norris J. R., Shankland D. Nerve blocking effect of Bacillus thuringiensis protein toxin. J. Invertebr. Pathol. 1969; 13: 461
  • Dastidar P. G., Nickerson K. W. Lysinoalamine in alkali-solubilized protein crystal toxin from Bacillus thuringiensis. FEMS Microbiol. Lett. 1978; 4: 331
  • Debabov V. G., Azizbekyran R. R., Khlebalina O. I., D'yachenko V. V., Galushka F. P., Belykh R. A. Isolation and preliminary characterization of extrachromosomal elements of Bacillus thuringiensisDNA. Genetika 1977; 13: 496
  • de Barjac H., Bonnefoi A. Maize au point sur la classification des Bacillus thuringiensis. Entomophaga 1973; 18: 5
  • de Barjac H., Bonnefoi A. A classification of strains of Bacillus thuringiensis, Berliner with a key to their differentiation. J. Invertebr. Pathol. 1968; 11: 335
  • de Barjac H. Toxicité de Bacillus thuringiensis var. israelensis pour les larves d'Aedes aegypti et d' Anopheles stephensi. C. R. Acad. Sci. 1978; 286: 175
  • de Barjac H. Une norvelle variété de Bacillus thuringiensis très toxique pour les moustiques: B. thuringiensis var. israelensis sérotype 14. C.R. Acad. Sci. 1978; 286: 797
  • Decker S., Maier S. Fine structure of mesosomal involvement during Bacillus macerans spoliation. J. Bacteriol. 1975; 121: 363
  • Delafield F. P., Somerville H. J., Rittenberg S. C. Immunological homology between crystal and spore protein of Bacillus thuringiensis. J. Bacteriol. 1968; 96: 713
  • Doi R. H. Changes in nucleic acids during speculation. The Bacterial Spore, G. Could, A. Hurst. Academic Press, New York 1969; 125
  • Doi R. H. Role of proteases in sporulation. Current Topics in Cellular Regulation, B. L. Horecker, E. R. Stadtman. Academic Press, New York 1972; Vol. 6: 1
  • Edlund T., Sidén I., Bowman H. G. Evidence for two immune inhibitors from Bacillus thuringiensis interfering with the humoral defense system of saturnid pupae. Infect. Immun. 1976; 14: 934
  • Eisenstadt E., Silver S. Calcium transport during sporulation in Bacillus subtilis. Spores V, H. O. Halvorson, R. Hanson, L. L. Campbell. American Society for Microbiology, Washington, D.C. 1972; 180
  • Ellar D. J., Lundgren D. G. Fine structure of sporulation in Bacillus cereusgrown in a chemically defined medium. J. Bacteriol. 1966; 92: 1748
  • Ermakova L. M., Galushka F. P., Strongin A. ya., Sladkova I. A., Rebentish B. A., Andreeva M. V., Stepanov V. M. Plasmids of crystal-forming bacilli and the influence of growth medium composition on their appearance. J. Gen. Microbiol. 1978; 107: 169
  • Fast P. G. The d-endotoxin of Bacillus thuringiensis III. A rapid method for separating parasporal bodies from spores. J. Invertebr. Pathol. 1972; 20: 139
  • Fast P. G., Angus T. A. The Endotoxin of Bacillus thuringiensis var. sotto: a toxic low molecular weight fragment. J. Invertebr. Pathol. 1970; 16: 465
  • Fast F. G., Donaghue T. P. The Endotoxin of Bacillus thuringiensis II. On the mode of action. J. Invertebr. Pathol. 1971; 18: 135
  • Fast P. G., Morrison I. K. The Endotoxin of Bacillus thuringiensis IV. The effect of S-delta-endotoxin on ion regulation by midgut tissue of Bombyx mori larvae. J. Invertebr. Pathol. 1972; 20: 208
  • Faust R. M., Hallam G. M., Travers R. S. Degradation of the parasporal crystal produced by Bacillus thuringiensis var. kurstaki. J. Invertebr. Pathol. 1974; 2: 365
  • Faust R. M., Travers R. S., Hallam E. M. Preliminary investigations on the molecular mode of action of the S-delta-endotoxin produced by Bacillus thuringiensis var, alesti. J. Invertebr. Pathol. 1974; 23: 259
  • Fitz-James P. C. Participation of the cytoplasmic membrane in growth and spore formation of bacilli. J. Biophys. Biochem. Cytol. 1960; 8: 507
  • Fitz-James P. C. The Initial Formation of Parasporal Inclusions in Bacilli. Proc. 5th Intl. Congr. Electron Microscopy. 1962; RR-10
  • Fooke-Achterrath M., Lickfeld K. G., Reusch V. M., Jr., Aebi U., Tschöpe U., Menge B. Close-to-life preservation of Staphylococcus aureus mesosomes for transmission electron microscopy. J. Ultrastruct. Res. 1974; 49: 270
  • Fowler E. H., Harrison J. A. The study of a parasporal body of an aerobi sporeforming bacillus. Bacteriol. Proc 1952; 30
  • Freeze E., Klofat W., Gallius E. Commitment to sporulation and induction of glucose-phosphoenol-pyruvate transferase. Biochim. Biophys, Acta 1970; 222: 265
  • Gerhardt P., Ribi E. infrastructure of the exosporium enveloping spores of Bacillus cereus. J. Bacteriol. 1964; 84: 1774
  • Ghosh B. K. The meosome a clue to the evolution of the plasma membrane. Sub Cell. Biochem. 1974; 3: 311
  • Gillespie J. B. A Comparative Study of the Parasporal Inclusions of Bacillus medusa. Ph.D. thesis, University of Western Ontario, London, Ontario 1969
  • Glatron M. F., Lecadet M. M., Dedonder R. Structure of the parasporal inclusion of Bacillus thuringiensis Berliner: characterization of a repetitive subunit. Eur. J. Biochem. 1972; 30: 330
  • Glatron M. F., Rapoport G. Biosynthesis of the parasporal inclusion of Bacillus thuringiensis: half-life of its corresponding messenger RNA. Biochimie 1972; 54: 1291
  • Gordon R. E., Haynes W. C., Pang C. H.-N. The Genus Bacillus. U.S. Department of Agriculture, Washington, D.C. 1973, Agriculture Handbook No. 427
  • Grahme-Smith D. G., Isaac P., Heal D. J., Bond R. P. M. Inhibiting of adenyl cyclase by an exotoxin of Bacillus thuringiensis. Nature (London) 1975; 253: 58
  • Greenleaf A. L., Linn T. G., Losick R. Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis. Proc. Natl. Acad. Sci. U.S.A. 1973; 70: 490
  • Griego V. M., Moffett D., Spence K. D. Inhibition of active K+ transport in the tobacco hornworm (Manduca sexta) midgut after ingestion of Bacillus thuringiensis endotoxin. J. Insect Physiol. 1979; 25: 283
  • Handley P. S., Knight D. G. Ultrastructural changes occurring during germination and outgrowth of spores of the thermophile Bacillus acidocaldarius. Arch. Microbiol. 1975; 102: 155
  • Hannay C. L. Crystalline inclusions in aerobic sporeforming bacteria. Nature (London) 1953; 172: 1004
  • Hannay C. L. Fowler's bacillus and its parasporal body. J. Biophys. Biochem. Cytol. 1961; 9: 285
  • Hannay C. L. Inclusions in bacteria. Bacterial Anatomy, 6th Symp. Soc. Gen. Microbiology. Cambridge University Press, New York 1956; 318
  • Hannay C. L., Fitz-James P. The protein crystals of Bacillus thuringiensis Berliner. Can. J. Microbiol. 1955; 1: 694
  • Hanson R. S., Peterson J. A., Yousten A. A. Unique biochemical events in bacterial spoliation. Annu. Rev. Microbiol. 1970; 24: 53
  • Hanson R. S., Srinivasan V. R., Halvorson H. O. Biochemistry of sporulation. I. Metabolism of acetate by vegetative and sporulating cells. J. Bacteriol. 1963; 85: 451
  • Hanson R. S., Srinivasan V. R., Halvorson H. O. Biochemistry of sporulation. II. Enzymatic changes during sporulation of Bacillus cereus. J. Bacteriol. 1963; 86: 45
  • Hashimoto T., Conti S. F. Ultrastructural changes associated with activation and germination of Bacillus cereus T. J. Bacteriol. 1971; 105: 361
  • Heimpel A. M. A critical review of Bacillus thuringiensis var. thuringiensis Berliner and other crystalliferous bacteria. Annu. Rev. Entomol. 1967; 12: 287
  • Heimpel A. M., Angus T. The site of action of crystalliferous bacteria in lepidoptera larvae. J. Insect Pathol. 1959; 1: 152
  • Herbert B. N., Gould H. J. Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworthi I. Kinetics of formation of the polypeptide components of the crystal protein, in vivo. Eur. J. Biochem. 1973; 37: 441
  • Herbert B. N., Gould H. J., Chain E. B. Crystal protein of Bacillus thuringiensis var. tolworthi: subunit structure and toxicity to Pieris brassicae. Eur. J. Biochem. 1971; 24: 366
  • Highton P. J. An electron microscopic study of the structure of mesosomal membranes in Bacillus licheniformis. J. Ultrastruct. Res. 1970; 31: 247
  • Highton P. J. An electron microscopic study of cell growth and mesosome structure of Bacillus licheniformis. J. Ultrastruct. Res. 1969; 26: 130
  • Highton P. J. Changes in the structure of mesosomes and cell membrane of Bacillus cereus during sporulation. Spores V, H. O. Halvorson, R. Hanson, L. L. Campbell. American Society for Microbiology, Washington, D.C. 1972; 13
  • Hitchins A. D. Polarity and topology of DNA segregation and septation in cells and sporangia of the bacilli. Can. J. Microbiol. 1978; 24: 1103
  • Holmes K. C., Munro R. E. Studies on the structure of parasporal inclusions from Bacillus thuringiensis. J. Mol. Biol. 1965; 14: 572
  • Holt S. C., Gauthier J. J., Tripper D. J. Ultrastructural studies of sporulation in Bacillus sphaericus. J. Bacteriol. 1975; 122: 1322
  • Holt S. C., Leadbetter E. R. Comparative ultrastructure of selected aerobic sporeforming bacteria: a freeze-etching study. Bacteriol. Rev. 1969; 133: 346
  • Iandolo J. J., Powell R. L., Bulla L. A., Jr. Dormant spores of Bacillus thurinensis contain an inhibitor of RNA polymerase. Biochem. Biophys. Res. Commun. 1976; 69: 237
  • Igarashi K., Yabuki M., Yoshioka Y., Euchi K., Hirose S. Mechanism of stimulation of polyphenylalamine synthesis by spermidine. Biochem. Biophys. Res. Commun. 1977; 75: 16
  • Ignoffo C. M. Effects of entomopathogens on vertebrates. Ann. N. Y. Acad. Sci. 1973; 217: 144
  • Johnson D. E., Bulla L. A., Jr., Nickerson K. W. Differential inhibition of β-exotoxin of vegetative- and sporulation-specific ribonucleic acid polymerases from Bacillus thuringiensis cells. Spores VI. American Society for Microbiology, Washington, D.C. 1975; 248
  • Kaneda T. Biosynthesis of branched chain fatty acids. II. Microbial synthesis of branched long chain fatty acids from certain short chain fatty acid substrates. J. Biol. Chem. 1963; 238: 1229
  • Kaneda T. Fatty acids of the genus Bacillus: an example of branched-chain preference. Bacteriol. Rev. 1977; 41: 391
  • Kaneda T. Fatty acids in the genus Bacillus II. Similarity in the fatty acid compositions of Bacillus thuringiensis, Bacillus anthracis, and Bacillus cereus. J. Bacteriol. 1968; 95: 2210
  • Kaneko I., Matsushima H. Crystalline inclusions in sporulating Bacillus subtilis cells. Spores VI. American Society for Microbiology, Washington, D.C 1975; 580
  • Katz E., Demain A. L. The peptide antibiotics of Bacillus: chemistry, biogenesis, and possible functions. Bacteriol. Rev. 1977; 41: 449
  • Keynan A., Halvorson H. Transformation of a dormant spore into a vegetative cell. Spores lit, L. L. Campbell, H. O. Halvorson. American Society of Microbiology, Ann Arbor, Mich. 1965; 74
  • Kingan S. L., Ensign J. C. Isolation and characterization of three autolytic enzymes associated with sporulation of Bacillus thuringiensis var. thuringiensis. J. Bacteriol. 1968; 96: 629
  • Kingan S. L., Ensign J. C. Chemical composition of the cell wall of Bacillus thuringiensis var. thuringiensis. J. Bacteriol. 1968; 95: 724
  • Kornfeld R., Kornfeld S. Comparative aspects of glycoprotein structure. Annu. Rev. Biochem. 1976; 45: 217
  • Klier A. F., Lecadet M.-M. Evidence in favour of the modification in vivo of RNA polymerase subunits during sporogenesis in Bacillus thuringiensis. Eur. J. Biochem. 1974; 47: 111
  • Klier A. F., Lecadet M.-M. Arguments based on hybridization-competition experiments in favor of the in vitro synthesis of sporulation-specific mRNAs by the RNA polymerase of B. thuringiensis. Biochem. Biophys. Res. Commun. 1976; 73: 263
  • Klier A. F., Lecadet M.-M., Dedonder R. Sequential modifications of DNA dependent RNA polymerase during sporogenesis in Bacillus thuringiensis. Eur. J. Biochem. 1973; 36: 317
  • Klier A., Lecadet M.-M., Rapoport G. Transcription in vitro of sporulation-specific RNA's by RNA polymerase from Bacillus thuringiensis. Spores VII, G. Chambliss, J. C. Vary. American Society for Microbiology, Washington, D.C. 1978; 205
  • Krywienzyk J., Angus T. A serological comparison of several crystalliferous insect pathogens. J. Invertebr. Pathol. 1967; 9: 126
  • Labaw L. W. The structure of Bacillus thuringiensis Berliner crystals. J. Ultrastruct. Res. 1964; 10: 66
  • Lacey L. A., Mulla M. S. Evaluation of Bacillus thuringiensis as a biocide of blackfly larvae (Diptera:Simuliidae). J. Invertebr. Pathol. 1977; 30: 46
  • Lang D. R., Lundgren D. G. Lipid composition of Bacillus cereus during growth and sporulation. J. Bacteriol. 1970; 101: 483
  • Lecadet M. M., Dedonder R. Biogenesis of the crystalline inclusion of Bacillus thuringiensis during sporulation. Eur. J. Biochem. 1971; 23: 282
  • Lecadet M. M., Dedonder R. Enzymatic hydrolysis of the crystals of Bacillus thuringiensis by the proteases of Pieris brassicae I. Preparation and fractionation of the lysates. J. Invertebr. Pathol. 1967; 9: 310
  • Lecadet M. M., Chevier G., Dedonder R. Analysis of a protein fraction in the spore coats of Bacillus thuringiensis. Eur. J. Biochem. 1972; 25: 349
  • Lecadet M.-M., Klier A. F., Ribier J. Isolation and characterization of two asporogeneous rifampicin resistant mutants of B. thuringiensis. Biochimie 1974; 56: 1471
  • Lecadet M., Lescourret M., Klier A. Characterization of an intracellular protease isolated from Bacillus thuringiensis sporulating cells and able to modify homologous RNA polymerase. Eur. J. Biochem. 1977; 79: 329
  • Lecadet M. M., Martouret D. Enzymatic hydrolysis of the crystals of Bacillus thuringiensis by the proteases of Pieris brassicae II. Toxicity of the different fractions of the hydrolysate for larvae of Pieris brassicae. J. Invertebr. Pathol. 1967; 9: 322
  • Lecadet M. M., Martouret D. La toxine figureée de B. thuringiensis Production enzymatique de substances solubles toxiques par injection. C. R. Acad. Sci 1962; 254: 2457
  • Linn T. G., Greenleaf A., Shorenstein R. G., Losick R. Loss of the sigma activity of RNA polymerase or Bacillus subtilis during sporulation. Proc. Natl. Acad. Sci. U.S.A. 1973; 70: 1865
  • Linnainman K., Sorsa M., Carlberg G., Gripenberg U., Meretoja T. Mutagenicity of Bacillus thuringiensis exotoxin. II. Submammalian tests. Hereditas 1977; 85: 113
  • Losick R., Shorenstein R. G., Sonenshein A. L. Structural alteration of RNA polymerase during sporulation. Nature (London) 1970; 227: 910
  • Lund B. M., Gee J. M., King N. R. The structure of the exosporium of a pigmented Clostridium. J. Gen. Microbiol. 1978; 105: 165
  • Lysenko O., Kucera M. Micro-organisms as sources of new insecticidal chemicals: toxins. Microbial Control of Insects and Mites. Academic Press, New York 1971; 205
  • Martin D. B., Vagelos P. R. The mechanism of tricarboxylic acid cycle regulation of fatty acid synthesis. J. Biol. Chem. 1962; 237: 1787
  • Matsuhashi M., Matsuhashi S., Lynen F. Biosynthesis of fatty acids, V. Acetyl coenzyme A carboxylase of rat liver and its activation by citric acid. Biochem. J. 1964; 340: 263
  • Mattes O. Parasitäre Krankheiten der Mehlmottenlarven und Versuche über ihre Verwendbarkeit als biologisches Bekamfungsmittel. Gesell. J. Beford. Ces. Naturw. Sitzber. Marburg 1927; 62: 381
  • Mackey B. M., Morris J. G. The exosporium of Clostridium pasteurianum. J. Gen Microbiol. 1972; 73: 325
  • Meenakshi K., Jayaraman K. On the formation of crystal proteins during sporulation in Bacillus thuringiensis var. thuringiensis. Arch. Microbiol. 1979; 120: 9
  • Meretoja T., Carlberg G., Gripenberg U., Linnainman K., Soisa M. Mutagenicity of Bacillus thuringiensis exotoxin I. Mammalian tests. Hereditas 1977; 85: 105
  • Milne R., Murphy D., Fast P. G. Bacillus thuringiensis d-endotoxin: an improved technique for the separation of crystals from spores. J. Invertebr. Pathol. 1977; 29: 30
  • Murrell W. G., Ohye D. F., Gordon R. A. Cytological and chemical structure of the spore. Spores IV. American Society for Microbiology, Washington, D.C. 1971; 1
  • Nagamatsu Y., Tsutsui R., Ichimaru T., Nagamatsu M., Koga K., Hayashi K. Subunit structure and toxic component of d-endotoxin from Bacillus thuringiensis. J. Invertebr. Pathol. 1978; 32: 103
  • Nakata H. M., Halvorson H. O. Biochemical changes occurring during growth and sporulation of Bacillus cereus. J. Bacteriol. 1960; 80: 801
  • Nanninga N. Structural features of mesosomes (chondroids) of Bacillus subtilis after freeze-etching. J. Cell Biol. 1968; 39: 251
  • Nickerson K. W., Bulla L. A., Jr. Physiology of sporeforming bacteria associated with insects: minimal nutritional requirements for growth, sporulation, and parasporal crystal formation. Appl. Microbiol. 1978; 28: 124
  • Nickerson K. W., Bulla L. A., Jr. Lipid metabolism during bacterial growth, sporulation, and germination: an obligate nutritional requirement in Bacillus thuringiensis for compounds that stimulate fatty acid synthesis. J. Bacteriol 1975; 123: 598
  • Nickerson K. W., Bulla L. A., Jr., Mounts T. L. Lipid metabolism during bacterial growth, sporulation, and germination: differential synthesis of individual branched- and normal-chain fatty acids during spore germination and outgrowth of Bacillus thuringiensis. J. Bacteriol. 1975; 124: 1256
  • Nickerson K. W., De Pinto J., Bulla L. A., Jr. Sporulation of Bacillus thuringiensis without concurrent derepression of the tricarboxylic acid cycle. J. Bacteriol. 1974; 117: 321
  • Nickerson K. W., St Julian G., Bulla L. A., Jr. Physiology of sporeforming bacteria associated with insects: a radiorespirometric survey of carbohydrate metabolism in the 12 serotypes of Bacillus thuringiensis. Appl. Microbiol. 1974; 28: 129
  • Nishiitsutsuji-Uwo J., Ohsawa A., Nishimura M. S. Factors affecting the insecticidal activity of Endotoxin of Bacillus thuringiensis. J. Invertebr. Pathol. 1977; 29: 162
  • Norris J. R., Burges H. D. Esterases of crystalliferous bacteria pathogenic for insects: epizootiological applications. J. Insect Pathol. 1963; 5: 460
  • Norris J. R. Macromolecule synthesis during sporulation of Bacillus thuringiensis. Spores IV, L. L. Campbell. American Society for Microbiology, Bethesda, Md. 1969; 45
  • Ohye D. F., Murrell W. G. Formation and structure of the spore of Bacillus coagulans. J. Cell Biol. 1962; 14: 111
  • Orrego C., Keijan P., Manca de Nadra M. C., Szulmajster J. Ribonucleic acid polymerase in a thermo-sensitive sporulation mutant (ts-4) of Bacillus subtilis. J. Bacteriol. 1973; 116: 636
  • Pendleton I. R. Toxic subunits of the crystal of Bacillus thuringiensis. J. Appl. Bacteriol. 1968; 31: 208
  • Perron J. M., Smirnoff W. A., Huot L. Comparaison de toxicité de quelques éléments pour Bacillus thuringiensis var. thuringiensis Berl. Can J. Microbiol. 1967; 13: 81
  • Prasad S. S. S. V. Studies on the Antitumour Activity of the Proteinaceous Crystal of Bacillus thuringiensis var. thuringiensis. Ph. D. thesis, Indian Institute of Science, Bangalore 1975
  • Prasad S. S. S. V., Kumari L., Shethna Y. I. Inhibitory activity of the proteinaceous crystal of Bacillus thuringiensis on Yoshida ascites sarcoma. Curr. Sci. 1973; 42: 568
  • Prasad S. S. S. V., Shethna Y. I. Induction of antitumour immunity by the proteinaceous crystal of Bacillus thuringiensis. Proc. Assoc. Microbiol. (India) 1994; 15: 9
  • Prasad S. S. S. V., Shethna Y. I. Purification, crystallization and partial characterization of the antitumour and insecticidal protein subunit from the d-endotoxin of Bacillus thuringiensis var. thuringiensis, Biochim. Biophys. Acta 1974; 363: 558
  • Prasad S. S. S. V., Shethna Y. I. Enhancement of immune response by the proteinaceous crystal of Bacillus thuringiensis var, thuringiensis. Biochim. Biophys. Res. Commun. 1975; 62: 517
  • Prasad S. S. S. V., Shethna Y. I. Antitumour immunity against YAS after treatment with proteinaceous crystal of Bacillus thuringiensis. Indian J. Exp. Biol. 1976; 14: 285
  • Prasad S. S. S. V., Shethna Y. I. Biochemistry and biological activities of the proteinaceous crystal of Bacillus thuringiensis. Indian J. Sci. Ind. Res. 1976; 35: 626
  • Prasad S. S. S. V., Shethna Y. I. Mode of action of the antitumour protein from the proteinaceous crystal of Bacillus thuringiensis. Antimicrob. Agents Chemother. 1976; 10: 293
  • Rain-Guion M.-C, Petit-Glatron M.-F., Klier A., Lecadet M.-M., Rapoport G. Coding capacity of the transcription products synthesized in vitro by the RNA polymerases from Bacillus thuringiensis. Biochem., Biophys. Res. Commun. 1976; 70: 709
  • Rajalkashmi S., Shethna Y. I. The effect of amino acids on growth, sporulation and crystal formation in Bacillus thuringiensis var. thuringiensis. J. Indian Inst. Sci. 1977; 59: 169
  • Reeves H. C., Rabin R., Wegener W. S., Ajl S. J. Fatty acid synthesis and metabolism in microorganisms. Annu. Rev. Microbiol. 1967; 21: 225
  • Remsen C. C. Fine structure of the mesosome and nucleoid in frozen-etched Bacillus subtilis. Arch. Mikrobiol. 1968; 61: 40
  • Remsen C. C. The fine structure of frozen-etched Bacillus cereus spores. Arch. Mikrobiol. 1966; 54: 266
  • Remsen C. C., Watson S. W. Freeze-etching of bacteria. Int. Rev. Cytol. 1972; 33: 253
  • Ribier J., Lecadet M. M. stude ultrastructurale et cinétique de la sporulation de Bacillus thuringiensis var. Berliner 1715. Remarques sur la formation de I'inclusion parasporale. Ann. Microbiol. (Inst. Pasteur) 1973; 124A: 311
  • Rode L. J., Lewis C. W., Jr., Foster J. W. Electron microscopy of spores of Bacillus megaterium with special reference to the effects of fixation and thin sectioning. J. Cell Biol. 1962; 13: 423
  • Rogoff M. H., Yousten A. A. Bacillus thuringiensis: microbiological considerations. Annu. Rev. Microbiol. 1969; 23: 357
  • Rousseau M., Flechon J., Hermier J. Etude an microscope electronique, de la germination de la spore chez Bacillus subtilis. Ann. Inst. Pasteur, Paris 1966; 111: 149
  • Santo L. Y., Doi R. H. Ultrastructural analysis during germination and outgrowth of Bacillus subtilis spores. J. Bacteriol. 1974; 120: 475
  • Sayles V. B., Aronson J. N., Rosenthal A. Small polypeptide components of the Bacillus thuringiensis parasporal crystalline inclusion. Biochem. Biophys. Res. Commun. 1970; 41: 1126
  • Scherrer P. S., Somerville H. J. Membrane fractions from the outer layers of spores of Bacillus thuringiensis with toxicity to lepidopterous larvae. Eur. J. Biochem. 1977; 72: 479
  • Schesser J. H., Sulla L. A., Jr. Toxicity of Bacillus thuringiensis spores to the tobacco horn-worm. Manduca sexta, Appl. Environ. Microbiol. 1978; 35: 121
  • Schesser J. H., Kramer K. J., Bulla L. A., Jr. Bioassay for homogeneous parasporal crystal of Bacillus thuringiensis using the tobacco hornworm. Manduca sexta, Appl. Environ. Microbiol. 1977; 33: 878
  • Scribner H. E., Mogelson J., Eisenstadt E., Silver S. Regulation of cation transport during bacterial sporulation. Spores VI. American Society for Microbiology, Washington, D.C. 1975; 346
  • Sharma C. B. S. R., Prasad S. S. S. V., Pai S. B., Sharma S. The exotoxin of Bacillus thuringiensis : a new C-mitotic agent. Experientia 1976; 32: 1465
  • Sharpe E. S. Toxicity of the parasporal crystal of Bacillus thuringiensis to Japanese beetle larvae. J. Invertebr. Pathol. 1976; 27: 421
  • Sharpe E. S., Nickerson K. W., Bulla L. A., Jr., Aronson J. N. Separation of spores and parasporal crystals of Bacillus thuringiensis in gradients of certain X-ray contrasting agents. Appl. Microbiol. 1975; 30: 1052
  • Shockman G. D. Symposium on the fine structure and replication of bacteria and their parts. IV. Unbalanced cell-wall synthesis: autolysis and cell-wall thickening. Bacteriol. Rev. 1965; 29: 345
  • Short J. A., Walker P. D., Thomson R. O., Somerville H. J. The fine structure of Bacillus finitimus, Bacillus thuringiensis spores with special reference to the location of crystal antigen. J. Gen. Microbiol. 1974; 84: 261
  • Silva M. T., Soma J. C. F., Polónia J. J., Macedo M. A. E., Parente A. M. Bacterial mesosomes real structures or artifacts. Biochim. Biophys. Acta 1976; 443: 92
  • Singer S., Goodman N. S., Rogoff M. H. Defined media for the study of bacilli pathogenic to insects. Ann. N. Y. Acad. Sci. 1966; 139: 16
  • Singer S., Rogoff M. H. Inhibition of growth of Bacillus thuringiensis by amino acids in defined media. J. Invertebr. Pathol. 1968; 12: 98
  • Smith N. R., Gordon R. E., Clark F. E. Aerobic Sporeforming Bacteria. U.S. Department of Agriculture, Washington, D.C. 1952, Agricultural Manog. No. 16
  • Somerville H. J. Formation of the parasporal inclusion of Bacillus thuringiensis. Eur. J., Biochem. 1971; 18: 226
  • Somerville H. J. Microbial toxins. Ann. N. Y. Acad. Sci. 1973; 217: 93
  • Somerville H. J. The insecticidal endotoxin of Bacillus thuringiensis. Pontif. Acad. Sci. Scr. Varia 1977; 41: 253
  • Somerville H. J. Insect toxin in spores and protein crystals of Bacillus thuringiensis. TIBS 1978; 3: 108
  • Somerville H. J., Delafield F. P., Rittenberg S. C. Biochemical homology between crystal and spore protein of Bacillus thuringiensis. J. Bacteriol. 1968; 96: 721
  • Somerville H. J., Delafield F. P., Rittenberg S. C. Urea-mercaptoethanol-soluble protein from spores of Bacillus thuringiensis and other species. J. Bacterial. 1970; 101: 551
  • Somerville H. J., James C. R. Association of the crystalline inclusion of Bacillus thuringiensis with the exosporium. J. Bacteriol 1970; 102: 580
  • Somerville H. J., Jones M. L. DNA competition studies within the Bacillus cereus groups of bacilli. J. Gen. Microbiol. 1977; 73: 257
  • Somerville H. J., Pockett H. V. An insect toxin from spores of Bacillus thuringienis. J. Gen. Microbiol. 1975; 87: 359
  • Somerville H. J., Pockett H. V. Phospholipase activity in gut juice of lepidopterous larvae. Insect Biochem. 1976; 6: 351
  • Somerville H. J., Swain H. M. Temperature-dependent inhibition of polyphenylalanine formation by the exotoxin of Bacillus thuringiensis. FEBS Lett. 1975; 54: 330
  • Stahly D. P., Dingman D. W., Bulla L. A., Jr., Aronson A. I. Possible origin and function of the parasporal crystals in Bacillus thuringiensis. Biochem. Biophys. Res. Commun. 1978; 84: 581
  • Stahly D. P., Dingman D. W., Irgens R. L., Field C. C., Feiss M. G., Smith G. L. Multiple extrachromosomal deoxyribonucleic acid molecules in Bacillus thuringiensis. FEMS Microbiol. Lett. 1978; 3: 139
  • Steinhaus E. A. Disease in a Minor Chord. Ohio State University Press, Columbus 1975
  • Steinhaus E. A. Possible use of Bacillus thuringiensis Berliner as an aid in the biological control of the alfalfa caterpillar. Hilgardia 1951; 20: 359
  • Stelma G. H., Jr., Aronson A. I., Fitz-James P. Properties of Bacillus cereus temperature-sensitive mutants altered in spore coat formation. J. Bacteriol. 1978; 134: 1157
  • Szulmajster J. Is sporulation a simple model for studying differentiation?. TIBS 1979; 4: 18
  • Tamir H., Gilvarg C. Density gradient centrifugation for the separation of sporulating forms of bacteria. J. Biol. Chem. 1966; 241: 1085
  • Thorne C. B. Transduction in Bacillus thuringiensis. Appl. Environ. Microbiol. 1978; 35: 1109
  • Toennies G. Role of amino acids in postexponential growth. J. Bacteriol. 1965; 90: 438
  • Toumanoff C. Virulence experimentale d'une souche banale de Bacillus cereus Frankland and Frankland pour les chenilles de Galleria melonella L Pieris brassicae. Ann. Inst. Pasteur Paris 1956; 90: 1
  • Travers R. S., Faust R. M., Reichelderfer C. F. Effects of Bacillus thuringiensis var. kurstaki Endotoxin on isolated lepidopteran mitochondria. J. Invertebr. Pathol. 1976; 28: 351
  • Vagelos P. R., Alberts A. W., Martin D. B. Studies on the mechanism of activation of acetyl coenzyme A carboxylase by citrate. J. Biol. Chem. 1963; 238: 533
  • Vankova J. The heat-stable exotoxin of Bacillus thuringiensis. Folia Microbiol (Prague) 1978; 23: 162
  • Vinter V. Physiology and biochemistry of sporulation. The Bacterial Spore, G. Gould, A. Hurst. Academic Press, New York 1969; 73
  • Waite M., Wakil S. J. Studies on the mechanism of fatty acid synthesis. XII. Acetyl coenzyme A carboxylase. J. Biol. Chem. 1962; 237: 2750
  • Walker P. D. Cytology of spore formation and germination, J. Appl. Bacteriol. 1970; 33: 1
  • Watanabe T., Tsutui R., Iwahana H., Abe K. Chemistry of the toxic crystals produced by Bacillus thuringiensis. Proc. Joint United States-Japan Seminar on Microbial Control of Insect Pests, Shukosha, FukuokaJapan, 1967; 71
  • Weber K., Osborn M. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J. Biol. Chem. 1969; 244: 4406
  • Wise J., Swanson A., Halvorson H. O. Dipicolinic acid-less mutants of Bacillus thuringiensis. J. Bacteriol. 1967; 94: 2075
  • Young E. I., Fitz-James P. C. Chemical and morphological studies of bacteria spore formation. II. Spore and parasporal protein formation in Bacillus cereus var. alesti. J. Biophys. Biochem. Cytol. 1959; 6: 483
  • Yousten A. A., Rogoff M. H. Metabolism of Bacillus thuringiensis in relation to spore and crystal formation. J. Bacteriol. 1969; 100: 1229
  • Carson, Rachel. The Silent Spring. Fawcett, Greenwich, Conn. 1962; 261
  • Hannay C. L. 1953, personal communication
  • Bechtel D. B., Bulla L. A. 1979, unpublished data
  • Fitz-James P. C., Loewy D. 1979, unpublished data
  • Fitz-James P. C. 1979, unpublished data
  • Labaw L. W. 1964, personal communication
  • Fitz-James P. C., Gillespie J. B., Loewy A. C. 1980, unpublished data
  • Bulla L. A. 1980, unpublished result
  • Bulla L. A. 1979, unpublished data

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