Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria

References

• Ambler RP. (1980). The structure of beta-lactamases. Philos Trans R Soc Lond, B, Biol Sci, 289, 321–331.
   PubMed Web of Science ®Google Scholar
• Ayalew K, Nambiar S, Yasinskaya Y, Jantausch BA. (2003). Carbapenems in pediatrics. Ther Drug Monit, 25, 593–599.
   PubMed Web of Science ®Google Scholar
• Barlow M, Reik RA, Jacobs SD, Medina M, Meyer MP, McGowan JE Jr, Tenover FC. (2008). High rate of mobilization for blaCTX-Ms. Emerging Infect Dis, 14, 423–428.
   PubMedGoogle Scholar
• Bauernfeind A, Grimm H, Schweighart S. (1990). A new plasmidic cefotaximase in a clinical isolate of Escherichia coli. Infection, 18, 294–298.
   PubMed Web of Science ®Google Scholar
• Baughman RP. (2009). The use of carbapenems in the treatment of serious infections. J Intensive Care Med, 24, 230–241.
   PubMedGoogle Scholar
• Birnbaum J, Kahan FM, Kropp H, MacDonald JS. (1985). Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin. Am J Med, 78, 3–21.
   PubMed Web of Science ®Google Scholar
• Borgianni L, Prandi S, Salden L, Santella G, Hanson ND, Rossolini GM, Docquier JD. (2011). Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. Antimicrob Agents Chemother, 55, 140–145.
   PubMed Web of Science ®Google Scholar
• Boucher HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB, Scheld M, Spellberg B, Bartlett J. (2009). Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis, 48, 1–12.
   PubMed Web of Science ®Google Scholar
• Bugg TD, Walsh CT. (1992). Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance. Nat Prod Rep, 9, 199–215.
   PubMed Web of Science ®Google Scholar
• Bush K. (2010a). Alarming ß-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae. Curr Opin Microbiol, 13, 558–564.
   PubMed Web of Science ®Google Scholar
• Bush K. (2010b). The coming of age of antibiotics: discovery and therapeutic value. Ann N Y Acad Sci, 1213, 1–4.
   Google Scholar
• Bush K, Jacoby GA. (2010). Updated functional classification of beta-lactamases. Antimicrob Agents Chemother, 54, 969–976.
   PubMed Web of Science ®Google Scholar
• Bush K, Pucci MJ. (2011). New antimicrobial agents on the horizon. Biochem Pharmacol, 82, 1528–1539.
   PubMed Web of Science ®Google Scholar
• Bush K, Jacoby GA, Medeiros AA. (1995). A functional classification scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother, 39, 1211–1233.
   PubMed Web of Science ®Google Scholar
• Butler MS, Buss AD. (2006). Natural products–the future scaffolds for novel antibiotics? Biochem Pharmacol, 71, 919–929.
   PubMed Web of Science ®Google Scholar
• Butler MS, Cooper MA. (2011). Antibiotics in the clinical pipeline in 2011. J Antibiot, 64, 413–425.
   PubMed Web of Science ®Google Scholar
• Cambray G, Guerout AM, Mazel D. (2010). Integrons. Annu Rev Genet, 44, 141–166.
   PubMed Web of Science ®Google Scholar
• Carattoli A. (2009). Resistance plasmid families in Enterobacteriaceae. Antimicrob Agents Chemother, 53, 2227–2238.
   PubMed Web of Science ®Google Scholar
• Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. (2005). Identification of plasmids by PCR-based replicon typing. J Microbiol Methods, 63, 219–228.
   PubMed Web of Science ®Google Scholar
• Cardoso LS, Araujo MI, Góes AM, Pacífico LG, Oliveira RR, Oliveira SC. (2007). Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis. Microb Cell Fact, 6, 1.
   PubMed Web of Science ®Google Scholar
• Castanheira M, Toleman MA, Jones RN, Schmidt FJ, Walsh TR. (2004). Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase. Antimicrob Agents Chemother, 48, 4654–4661.
   PubMed Web of Science ®Google Scholar
• Chaudhuri BN, Rodrigues C, Balaji V, Iyer R, Sekar U, Wattal C, Chitnis DS, Dhole TN, Joshi S. (2011). Incidence of ESBL producers amongst Gram-negative bacilli isolated from intra-abdominal infections across India (based on SMART study, 2007 data). J Assoc Physicians India, 59, 287–292.
   PubMedGoogle Scholar
• Chopra I, Roberts M. (2001). Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev, 65, 232– 60; second page, table of contents.
   PubMed Web of Science ®Google Scholar
• Coates A, Hu Y, Bax R, Page C. (2002). The future challenges facing the development of new antimicrobial drugs. Nat Rev Drug Discov, 1, 895–910.
   PubMed Web of Science ®Google Scholar
• Delcour AH. (2009). Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta, 1794, 808–816.
   PubMed Web of Science ®Google Scholar
• Dineen P. (1976). Antibacterial activity of oxidized regenerated cellulose. Surg Gynecol Obstet, 142, 481–486.
   PubMedGoogle Scholar
• Dobrindt U, Hochhut B, Hentschel U, Hacker J. (2004). Genomic islands in pathogenic and environmental microorganisms. Nat Rev Microbiol, 2, 414–424.
   Google Scholar
• Drlica K, Snyder M. (1978). Superhelical Escherichia coli DNA: relaxation by coumermycin. J Mol Biol, 120, 145–154.
   PubMed Web of Science ®Google Scholar
• Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, Poirel L, Richet H, Robert C, Mangenot S, Abergel C, Nordmann P, Weissenbach J, Raoult D, Claverie JM. (2006). Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet, 2, e7.
   PubMed Web of Science ®Google Scholar
• Gupta V. (2008). Metallo beta lactamases in Pseudomonas aeruginosa and Acinetobacter species. Expert Opin Investig Drugs, 17, 131–143.
   PubMed Web of Science ®Google Scholar
• Harada S, Ishii Y, Yamaguchi K. (2008). Extended-spectrum beta-lactamases: implications for the clinical laboratory and therapy. Korean J Lab Med, 28, 401–412.
   PubMedGoogle Scholar
• Höltje JV. (1998). Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli. Microbiol Mol Biol Rev, 62, 181–203.
   PubMed Web of Science ®Google Scholar
• Jones RN, Biedenbach DJ, Sader HS, Fritsche TR, Toleman MA, Walsh TR. (2005). Emerging epidemic of metallo-beta-lactamase-mediated resistances. Diagn Microbiol Infect Dis, 51, 77–84.
   PubMed Web of Science ®Google Scholar
• Katz L, Ashley GW. (2005). Translation and protein synthesis: macrolides. Chem Rev, 105, 499–528.
   PubMed Web of Science ®Google Scholar
• Kohanski MA, Dwyer DJ, Collins JJ. (2010). How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol, 8, 423–435.
   PubMed Web of Science ®Google Scholar
• Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, Chaudhary U, Doumith M, Giske CG, Irfan S, Krishnan P, Kumar AV, Maharjan S, Mushtaq S, Noorie T, Paterson DL, Pearson A, Perry C, Pike R, Rao B, Ray U, Sarma JB, Sharma M, Sheridan E, Thirunarayan MA, Turton J, Upadhyay S, Warner M, Welfare W, Livermore DM, Woodford N. (2010). Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis, 10, 597–602.
   PubMed Web of Science ®Google Scholar
• Lamb HM, Ormrod D, Scott LJ, Figgitt DP. (2002). Ceftriaxone: an update of its use in the management of community-acquired and nosocomial infections. Drugs, 62, 1041–1089.
   PubMed Web of Science ®Google Scholar
• Lartigue MF, Poirel L, Aubert D, Nordmann P. (2006). In vitro analysis of ISEcp1B-mediated mobilization of naturally occurring beta-lactamase gene blaCTX-M of Kluyvera ascorbata. Antimicrob Agents Chemother, 50, 1282–1286.
   PubMed Web of Science ®Google Scholar
• Lauretti L, Riccio ML, Mazzariol A, Cornaglia G, Amicosante G, Fontana R, Rossolini GM. (1999). Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother, 43, 1584–1590.
   PubMed Web of Science ®Google Scholar
• Lee K, Yum JH, Yong D, Lee HM, Kim HD, Docquier JD, Rossolini GM, Chong Y. (2005). Novel acquired metallo-beta-lactamase gene, bla(SIM-1), in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea. Antimicrob Agents Chemother, 49, 4485–4491.
   PubMed Web of Science ®Google Scholar
• Li XZ, Nikaido H. (2004). Efflux-mediated drug resistance in bacteria. Drugs, 64, 159–204.
   PubMed Web of Science ®Google Scholar
• Li XZ, Nikaido H. (2009). Efflux-mediated drug resistance in bacteria: an update. Drugs, 69, 1555–1623.
   PubMed Web of Science ®Google Scholar
• Livermore DM, Woodford N. (2000). Carbapenemases: a problem in waiting? Curr Opin Microbiol, 3, 489–495.
   PubMed Web of Science ®Google Scholar
• Marchiaro P, Viale AM, Ballerini V, Rossignol G, Vila AJ, Limansky A. (2010). First report of a Tn402-like class 1 integron carrying blaVIM-2 in Pseudomonas putida from Argentina. J Infect Dev Ctries, 4, 412–416.
   PubMed Web of Science ®Google Scholar
• Mazel D. (2006). Integrons: agents of bacterial evolution. Nat Rev Microbiol, 4, 608–620.
   PubMed Web of Science ®Google Scholar
• Mendes RE, Castanheira M, Toleman MA, Sader HS, Jones RN, Walsh TR. (2007). Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6′)-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. Antimicrob Agents Chemother, 51, 2611–2614.
   PubMed Web of Science ®Google Scholar
• Mohr JF 3rd., Ostrosky-Zeichner L, Wainright DJ, Parks DH, Hollenbeck TC, Ericsson CD. (2008). Pharmacokinetic evaluation of single-dose intravenous daptomycin in patients with thermal burn injury. Antimicrob Agents Chemother, 52, 1891–1893.
   PubMed Web of Science ®Google Scholar
• Naas T, Cuzon G, Villegas MV, Lartigue MF, Quinn JP, Nordmann P. (2008). Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene. Antimicrob Agents Chemother, 52, 1257–1263.
   PubMed Web of Science ®Google Scholar
• Naseer U, Natås OB, Haldorsen BC, Bue B, Grundt H, Walsh TR, Sundsfjord A. (2007). Nosocomial outbreak of CTX-M-15-producing E. coli in Norway. APMIS, 115, 120–126.
   PubMed Web of Science ®Google Scholar
• Nikaido H. (2003). Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev, 67, 593–656.
   PubMed Web of Science ®Google Scholar
• Nordmann P, Cuzon G, Naas T. (2009). The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis, 9, 228–236.
   PubMed Web of Science ®Google Scholar
• Novais A, Comas I, Baquero F, Cantón R, Coque TM, Moya A, González-Candelas F, Galán JC. (2010). Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance. PLoS Pathog, 6, e1000735.
   PubMed Web of Science ®Google Scholar
• Osano E, Arakawa Y, Wacharotayankun R, Ohta M, Horii T, Ito H, Yoshimura F, Kato N. (1994). Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrob Agents Chemother, 38, 71–78.
   PubMed Web of Science ®Google Scholar
• Pape T, Wintermeyer W, Rodnina MV. (2000). Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nat Struct Biol, 7, 104–107.
   PubMedGoogle Scholar
• Partridge SR, Zong Z, Iredell JR. (2011). Recombination in IS26 and Tn2 in the evolution of multiresistance regions carrying blaCTX-M-15 on conjugative IncF plasmids from Escherichia coli. Antimicrob Agents Chemother, 55, 4971–4978.
   PubMed Web of Science ®Google Scholar
• Paterson DL, Bonomo RA. (2005). Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev, 18, 657–686.
   PubMed Web of Science ®Google Scholar
• Pitout JD. (2010). Infections with extended-spectrum beta-lactamase-producing enterobacteriaceae: changing epidemiology and drug treatment choices. Drugs, 70, 313–333.
   PubMed Web of Science ®Google Scholar
• Plosker GL, Foster RH, Benfield P. (1998). Cefotaxime. A pharmacoeconomic review of its use in the treatment of infections. Pharmacoeconomics, 13, 91–106.
   Google Scholar
• Poirel L, Nordmann P. (2006). Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect, 12, 826–836.
   PubMed Web of Science ®Google Scholar
• Poirel L, Lagrutta E, Taylor P, Pham J, Nordmann P. (2010a). Emergence of metallo-ß-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia. Antimicrob Agents Chemother, 54, 4914–4916.
   PubMed Web of Science ®Google Scholar
• Poirel L, Rodríguez-Martínez JM, Al Naiemi N, Debets-Ossenkopp YJ, Nordmann P. (2010b). Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. Antimicrob Agents Chemother, 54, 2420–2424.
   PubMed Web of Science ®Google Scholar
• Poirel L, Decousser JW, Nordmann P. (2003). Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase gene. Antimicrob Agents Chemother, 47, 2938–2945.
   PubMed Web of Science ®Google Scholar
• Poirel L, Magalhaes M, Lopes M, Nordmann P. (2004). Molecular analysis of metallo-beta-lactamase gene bla(SPM-1)-surrounding sequences from disseminated Pseudomonas aeruginosa isolates in Recife, Brazil. Antimicrob Agents Chemother, 48, 1406–1409.
   PubMed Web of Science ®Google Scholar
• Powers JH. (2004). Antimicrobial drug development–the past, the present, and the future. Clin Microbiol Infect, 10 Suppl 4, 23–31.
   PubMed Web of Science ®Google Scholar
• Queenan AM, Bush K. (2007). Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev, 20, 440–58, table of contents.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Martinez JM, Poirel L, Canton R, Nordmann P. (2006). Common region CR1 for expression of antibiotic resistance genes. Antimicrob Agents Chemother, 50, 2544–2546.
   PubMed Web of Science ®Google Scholar
• Sajjad A, Holley MP, Labbate M, Stokes HW, Gillings MR. (2011). Preclinical class 1 integron with a complete Tn402-like transposition module. Appl Environ Microbiol, 77, 335–337.
   Google Scholar
• Salabi AE, Toleman MA, Weeks J, Bruderer T, Frei R, Walsh TR. (2010). First report of the metallo-beta-lactamase SPM-1 in Europe. Antimicrob Agents Chemother, 54, 582.
   PubMed Web of Science ®Google Scholar
• Samuelsen O, Toleman MA, Sundsfjord A, Rydberg J, Leegaard TM, Walder M, Lia A, Ranheim TE, Rajendra Y, Hermansen NO, Walsh TR, Giske CG. (2010). Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates from Norway and Sweden shows import of international clones and local clonal expansion. Antimicrob Agents Chemother, 54, 346–352.
   PubMed Web of Science ®Google Scholar
• Santos C, Caetano T, Ferreira S, Mendo S. (2010). Tn5090-like class 1 integron carrying bla(VIM-2) in a Pseudomonas putida strain from Portugal. Clin Microbiol Infect, 16, 1558–1561.
   Google Scholar
• Schmidt H, Hensel M. (2004). Pathogenicity islands in bacterial pathogenesis. Clin Microbiol Rev, 17, 14–56.
   PubMed Web of Science ®Google Scholar
• Sekiguchi J, Morita K, Kitao T, Watanabe N, Okazaki M, Miyoshi-Akiyama T, Kanamori M, Kirikae T. (2008). KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. Antimicrob Agents Chemother, 52, 4194–4197.
   PubMedGoogle Scholar
• Shah PM, Isaacs RD. (2003). Ertapenem, the first of a new group of carbapenems. J Antimicrob Chemother, 52, 538–542.
   PubMed Web of Science ®Google Scholar
• Smillie C, Garcillán-Barcia MP, Francia MV, Rocha EP, de la Cruz F. (2010). Mobility of plasmids. Microbiol Mol Biol Rev, 74, 434–452.
   PubMed Web of Science ®Google Scholar
• Toleman MA, Simm AM, Murphy TA, Gales AC, Biedenbach DJ, Jones RN, Walsh TR. (2002). Molecular characterization of SPM-1, a novel metallo-beta-lactamase isolated in Latin America: report from the SENTRY antimicrobial surveillance programme. J Antimicrob Chemother, 50, 673–679.
   PubMed Web of Science ®Google Scholar
• Toleman MA, Walsh TR. (2011). Combinatorial events of insertion sequences and ICE in Gram-negative bacteria. FEMS Microbiol Rev, 35, 912–935.
   Google Scholar
• Toleman MA, Vinodh H, Sekar U, Kamat V, Walsh TR. (2007). blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3′ conserved sequence. Antimicrob Agents Chemother, 51, 2636–2638.
   Google Scholar
• Toleman MA, Bennett PM, Walsh TR. (2006). Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons. J Antimicrob Chemother, 58, 1–6.
   PubMedGoogle Scholar
• Vaara M. (1992). Agents that increase the permeability of the outer membrane. Microbiol Rev, 56, 395–411.
   PubMedGoogle Scholar
• Wagner A, Lewis C, Bichsel M. (2007). A survey of bacterial insertion sequences using IScan. Nucleic Acids Res, 35, 5284–5293.
   Google Scholar
• Waksman SA, Woodruff HB. (1942). Selective Antibiotic Action of Various Substances of Microbial Origin. J Bacteriol, 44, 373–384.
   PubMedGoogle Scholar
• Waldor MK. (2010). Mobilizable genomic islands: going mobile with oriT mimicry. Mol Microbiol, 78, 537–540.
   Google Scholar
• Walsh C, Duffy G, O’Mahony R, Fanning S, Blair IS, McDowell DA. (2006). Antimicrobial resistance in Irish isolates of verocytotoxigenic Escherichia coli (E. coli)–VTEC. Int J Food Microbiol, 109, 173–178.
   Google Scholar
• Walsh TR. (2010). Emerging carbapenemases: a global perspective. Int J Antimicrob Agents, 36 Suppl 3, S8–14.
   Google Scholar
• Walsh TR, Toleman MA, Poirel L, Nordmann P. (2005). Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev, 18, 306–325.
   PubMed Web of Science ®Google Scholar
• Walther-Rasmussen J, Høiby N. (2006). OXA-type carbapenemases. J Antimicrob Chemother, 57, 373–383.
   PubMed Web of Science ®Google Scholar
• Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, Walsh TR. (2009). Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother, 53, 5046–5054.
   PubMed Web of Science ®Google Scholar
• Yu YS, Qu TT, Zhou JY, Wang J, Li HY, Walsh TR. (2006). Integrons containing the VIM-2 metallo-beta-lactamase gene among imipenem-resistant Pseudomonas aeruginosa strains from different Chinese hospitals. J Clin Microbiol, 44, 4242–4245.
   Google Scholar
• Zhanel GG, Wiebe R, Dilay L, Thomson K, Rubinstein E, Hoban DJ, Noreddin AM, Karlowsky JA. (2007). Comparative review of the carbapenems. Drugs, 67, 1027–1052.
   PubMed Web of Science ®Google Scholar
• Zhao WH, Chen G, Ito R, Hu ZQ. (2009). Relevance of resistance levels to carbapenems and integron-borne blaIMP-1, blaIMP-7, blaIMP-10 and blaVIM-2 in clinical isolates of Pseudomonas aeruginosa. J Med Microbiol, 58, 1080–1085.
   PubMed Web of Science ®Google Scholar