1,467
Views
286
CrossRef citations to date
0
Altmetric
Review Article

Exposure, Health and Ecological Effects Review of Engineered Nanoscale Cerium and Cerium Oxide Associated with its Use as a Fuel Additive

, , , , , & show all
Pages 213-229 | Received 16 Jul 2010, Accepted 29 Sep 2010, Published online: 18 Jan 2011

References

  • Berry JP, Meignan M, Escaig F and Galle P (1988). Inhaled Soluble Aerosols Insolubilised by Lysosomes of Alveolar Cells. Application to Some Toxic Compounds; Electron Microprobe and Ion Microprobe Studies. Toxicology, 52, 127–39.
  • Boecker BB, and Cuddihy RG (1974). Toxicity of 144Ce Inhaled as 144CeCl3 by the beagle: metabolism and dosimetry. Radiat Res 60(1):133–154.
  • Brl 1994. Final Report for A 90-Day Inhalation Neurotoxicity and Toxicity Study by Exposure to a Dry Powder Aerosol of Ceric Oxide in the Albino Rat. Montreal.
  • Brunner TJ, Wick P, Manser P, Spohn P, Grass RN, Limbach LK, Bruinink A and Stark WJ 2006. In Vitro Cytotoxicity of Oxide Nanoparticles: Comparison to Asbestos, Silica, and the Effect of Particle Solubility. Environ Sci Technol, 40, 4374–81.
  • Cassee FR, Gosens I, Boere AJF, Modulation by nanosized cerium oxide of the toxicity of inhaled diesel engine exhaust. In preparation.
  • CIP, (2006) Chemical Information Profile for Ceric Oxide [CAS No. 1306-38-3], Supporting Nomination for Toxicological Evaluation by the National Toxicology Program January 2006 Web: http://ntp.niehs.nih.gov/files/Ceric_oxide2.pdf.
  • Eapen, JT (1997) Cerium Levels are Elevated in the Serum of Patients with Endomyocardial Fibrosis (EMF) Biological Trace Element Research, 59, 41–44.
  • Eom HJ and Choi J (2009). Oxidative Stress of CeO2 Nanoparticles Via P38-Nrf-2 Signaling Pathway in Human Bronchial Epithelial Cell, Beas-2b. Toxicol Lett, 187, 77–83.
  • EPA, U. S. (2007), Nanotechnology White Paper. EPA 100/B-07/February 2007. http://www.epa.gov/osa/pdfs/nanotech/epa-nanotechnology-whitepaper-0207.pdf
  • EPA, U. S. (Sept. 2009). Toxicological Review of Cerium Oxide and Cerium Compounds. EPA/635/R-08/002F. http://www.epa.gov/iris/toxreviews/1018tr.pdf
  • Fall M, Guerbet M, Park B, Gouriou F, Dionnet F and Morin JP (2007). Evaluation of Cerium Oxide and Cerium Oxide Based Fuel Additive Safety on Organotypic Cultures of Lung Slices. Nanotoxicology, 1, 227–234.
  • Farfaletti F, et al. (2005). Effect of Water\Fuel Emulsions and Cerium Based Combustion Improver Additive on HD and LD Diesel Exhaust Emissions. Environ. Sci. Technol., 39, 6792–6799.
  • Galle P, Berry JP and Galle C (1992). Role of Alveolar Macrophages in Precipitation of Mineral Elements Inhaled as Soluble Aerosols. Environ Health Perspect, 97, 145–7.
  • Geiser M, Rothen-Rutishauser B, Kapp N, Schurch S, Kreyling W, Schulz H, Semmler M, Vinzenz IH, heyder J, Gehr P (2005). Ultrafine Particles Cross Cellular Membranes by Nonphagocytic Mechanisms in Lungs and Cells. Environ. Health Perspect. 113, 1555–1560.
  • Gojova A, Lee, JT, Jung HS, Guo B, Barakat, AI and Kennedy IM (2009). Effect of Cerium Oxide Nanoparticles on Inflammation in Vascular Endothelial Cells. Inhal Toxicol, 21 Suppl 1, 123–30.
  • Gómez-Aracena J, Riemersma RA, Gutiérrez-Bedmar M, Boden P, Kark JD, Garcia-Rodríguez A, Gorgojo L, Veer PV, Fernández-Crehuet J, Kok FJ and Martin-Moreno JM (2006). Toenail Cerium Levels and Risk of first Acute Myocardial Infarction: The Euramic and Heavy Metals Study. Chemosphere, 64, 112–120.
  • Heckert EG, Karakoti AS, Seal S and Self WT (2008). The Role of Cerium Redox State in the Sod Mimetic Activity of Nanoceria. Biomaterials, 29, 2705–2709.
  • HEI - Health Effects Institute, Research Report, 2001. Evaluation of Human Health Risk from Cerium added to Diesel Fuel. HEI Research Communication 9. North Andover Ma: Flagship Press. http://pubs.healtheffects.org/view.php?id = 172.
  • Hirano S and Suzuki KT (1996). Exposure, Metabolism, and Toxicity of Rare Earths and Related Compounds. Environ Health Perspect, 104, 85–95.
  • Hirst SM, Karakoti AS, Tyler RD, Sriranganathan N, Seal S and Reilly CM (2009). Anti-Inflammatory Properties of Cerium Oxide Nanoparticles. Small, 5, 2848–56.
  • Jung J, Kittelson DB, Zachariah MR (2005). The Influence of a Cerium Additive on Ultrafine Emissions and Kinetics of Oxidation. Combustion and Flame, 142, 276–288.
  • Keller, AA, Wang H, Zhou D, Lenihan HS, Cherr G, Cardinale BJ, Miller R, Ji Z (2010). Stability and aggregation of metal oxide nanoparticles in natural aqueous matrices. Environ. Sci. Technol. 44, 1962–1967.
  • Kreyling WG, Semmler-Behnke M, Seitz J, Scymczak W, Wenk A, Mayer P, Takenaka S, Oberdörster G (2009).Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs. Inhal Toxicol. Jul;21 Suppl 1:55–60.
  • Kutty VR, Abraham S and Kartha CC 1996. Geographical Distribution of Endomyocardial Fibrosis in South Kerala. International J Epidemiology, 25, 1202–1207.
  • Limbach LK, Bereiter R, Müller E, Krebs R, Galli R and Stark WJ (2008). Removal of Oxide Nanoparticles in a Model Wastewater Treatment Plant: Influence of Agglomeration and Surfactants on Clearing Efficiency. Environ Sci Technol, 42, 5828–5833.
  • Limbach LK, Li Y, Grass RN, Brunner TJ, Hintermann MA, Muller M, Gunther D and Stark WJ (2005). Oxide Nanoparticle Uptake in Human Lung Fibroblasts: Effects of Particle Size, Agglomeration, and Diffusion at Low Concentrations. Environ Sci Technol, 39, 9370–9376.
  • Lin W, Huang YW, Zhou XD and Ma Y (2006). Toxicity of Cerium Oxide Nanoparticles in Human Lung Cancer Cells. Int J Toxicol, 25, 451–7.
  • Linse S, Cabaleiro-Lago C, Xue WF, Lynch I, Lindman S, Thulin E, Radford SE and Dawson KA (2007). Nucleation of Protein Fibrillation by Nanoparticles. Proceedings of the National Academy of Sciences of the United States of America, 104, 8691–8696.
  • Lopez-Moreno ML, De La Rosa G, Hernandez JA, Peralta-Videa JR, Gardea-Torresdey JL (2010). X-ray absorption spectroscopy of CeO2 nanoparticles and assessment of their differential toxicity in four edible plants. Jour. Agric. Food Chem. 58, 3689–3693.
  • NIOSH - National Institute for Occupational Health and Safety (2002). Review of Technology Available to the Mining Industry for Control of Diesel Emissions. IC 9462 Information Circular. Department of Health and Human Serivices, Center for Disease Control. http://www.cdc.gov/niosh/mining/pubs/pdfs/ic9462.pdf
  • National Toxicology Program (2006). Chemical Information Profile for Ceric Oxide [CAS No. 1306-38-3]. February (2006). http://ntp.niehs.nih.gov/files/Ceric_oxide2.pdf
  • Oberdorster G, Oberdorster E, Oberdorster J (2005). Nanotoxicology: an Emerging Discipline Evolving from Studies of Ultrafine Particles. Environ. Health Perspect. 113, 823–839.
  • Pang X, Li D, and Peng A (2002). Application of rare-earth elements in the agriculture of China and its environmental behavior in soil. Environ Sci Pollut Res Int, 9(2):143–148.
  • Park B, Martin P, Harris C, Guest R, Whittingham A, Jenkinson P and Handley J (2007). Initial in Vitro Screening Approach to Investigate the Potential Health and Environmental Hazards of Enviroxtrade Mark - A Nanoparticulate Cerium Oxide Diesel Fuel Additive. Part Fibre Toxicol, 4, 12.
  • Park B, Donaldson K, Duffin R, Tran L, Kelly F, Mudway I, Morin JP, Guest R, Jenkinson P, Samaras Z, Giannouli M, Kouridis H and Martin P (2008a). Hazard and Risk Assessment of a Nanoparticulate Cerium Oxide-Based Diesel Fuel Additive - A Case Study. Inhal Toxicol, 20, 547–66.
  • Park EJ, Choi J, Park Y K and Park K (2008b). Oxidative Stress Induced by Cerium Oxide Nanoparticles in Cultured Beas-2b Cells. Toxicology, 245, 90–100.
  • Pirmohamed T, Dowding JM, Singh S, Wasserman B, Heckert E, Karakoti, AS, King JES, Seal S and Self WT. Nanoceria Exhibit Redox State-Dependent Catalase Mimetic Activity. Chemical Communications, 46, 2736–2738.
  • Preeta R and Nair RR (1999). Stimulation of Cardiac Fibroblast Proliferation by Cerium: a Superoxide Anion-Mediated Response. J Mol Cell Cardiol, 31, 1573–80.
  • Prospect 2009. Toxicological Review of Nano Cerium Oxide. In Support of Prospect: Ecotoxicology Test Protocols for Representative Nanomaterials in Support of the OECD Sponsorship Programme. http://www.nanotechia-prospect.org/managed_assets/files/prospect_nano-ceo2_literature_review.pdf
  • Quik JTK, Lynch I, Van Hoecke K, Miermans CJH, De Schamphelaere KAC, Janssen CR, Dawson KA, Stuart MAC, De Meent DV (2010). Effect of natural organic matter on cerium dioxide nanoparticles settling in model fresh water. Chemosphere, doi:10.1016/j.chemosphere.2010.07.062.
  • Rothen-Rutishauser B, Grass RN, Blank F, Limbach LK, Mühlfeld C, Brandenberger, C., Raemy DO, Gehr P and Stark WJ (2009). Direct Combination of Nanoparticle Fabrication And Exposure To Lung Cell Cultures In A Closed Setup as a Method To Simulate Accidental Nanoparticle Exposure Of Humans. Environ Sci Technol, 43, 2634–2640.
  • Sabbioni E, Pietra R, Gaglione P, Vocaturo G, Colombo F, Zanoni M, Rodi F (1982). Long-term occupational risk of rare-earth pneumoconiosis. A case report as investigated by neutron activation analysis. Sci Total Environ. Dec;26(1):19–32.
  • Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, Takenaka S, Schmid G, Brandau W (2008). Biodistribution of 1.4 and 18 nm Gold Particles in Rats. Small, 4(12), 2108–2111.
  • Staal Y, Ma-Hock L, Muijser H, Treunmann S, Strauss V and Landsiedel R (2010). Pulmonary Toxicity of Ceriumdioxide Particles is Modulated By Size and Coating: Inhalation Studies with Nano-, Aggregated Nano-, and Micron-Scale Particles and Particles with Different Surface Chemistry. 49th Annual Meeting of the Society Of Toxicology, Salt Lake City, March 7-11, 2010, Abstract # 1398.
  • Thill A, Zeyons O, Spalla O, Chauvat F, Rose J, Auffan M and Flank AM (2006). Cytotoxicity of CeO2 Nanoparticles for Escherichia Coli. Physico-Chemical Insight of the Cytotoxicity Mechanism. Environ Sci Technol, 40, 6151–6.
  • Thomas RL, Scott JK, Chiffelle TL. (1972). Metabolism and toxicity of inhaled 144Ce in rats. Radiat Res 49:589–610.
  • Van Berlo D, Albrecht C, Knaapen AM, Cassee FR, Gerlofs-Nijland ME, Kooter IM, Palomero-Gallagher N, Bidmon HJ, van Schooten FJ, Krutmann J, Schins RP Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain. Arch Toxicol. 2010 Jul; 84(7):553–62.
  • Van Hoecke K, Quik JTK, Mankiewicz-Boczek J, De Schamphelaere KAC, Elsaesser A, Van Der Meeren P, Barnes C, Mckerr G, Howard CV, Van De Meent D, Rydyñski K, Dawson KA, Salvati A, Lesniak A, Lynch I, Silversmit G, De Samber B, Vincze L and Janssen CR (2009). Fate and Effects of CeO2 Nanoparticles in Aquatic Ecotoxicity Tests. Environ Sci Technol, 43, 4537–4546.
  • Veranth JM, Kaser EG, Veranth MM, Koch M and Yost GS (2007). Cytokine Responses Of Human Lung Cells (Beas-2b) Treated With Micron-Sized and Nanoparticles of Metal Oxides Compared to Soil Dusts. Particle and Fibre Toxicology, 4.
  • Vocaturo G, Colombo F, Zanoni M, Rodi F, Sabbioni E, Pietra R (1983). Human exposure to heavy metals: rare earth pneumoconiosis in occupational workers. Chest 83(5):780–783.
  • Staal Y, Ma-Hock L, Muijser H, Treunmann S, Strauss V and Landsiedel R, Pulmonary Toxicity of Ceriumdioxide Particles is Modulated by Size and Coating: Inhalation Studies with Nano-, Aggregated Nano-, and Micron-Scale Particles and Particles with Different Surface Chemistry. 49th Annual Meeting of the Society of Toxicology, Salt Lake City, (March 7-11–2010), Abstract # 1398
  • Xia T, Kovochich M, Liong M, Madler L, Gilbert B, Shi H, Yeh JI, Zink JI and Nel AE (2008). Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties. Acs Nano, 2, 2121–34.
  • Yokel RA, Florence RL, Unrine JM, Tseng MT, Graham UM, Wu P, Grulke EA, Sultana R, Hardas SS and Butterfield DA (2009). Biodistribution and Oxidative Stress Effects of A Systemically-Introduced Commercial Ceria Engineered Nanomaterial. Nanotoxicology, 3, 234–248.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.