200
Views
150
CrossRef citations to date
0
Altmetric
Research Article

Aflatoxin Exposure in Human Populations: Measurements and Relationship to Cancer

, , &
Pages 113-145 | Published online: 26 Sep 2008

References

  • Perera F., Weinstein I. B. Molecular epidemiology and carcinogen DNA adduct detection: new approaches to studies of human cancer causation. J. Chronic Dis. 1982; 35: 581
  • Busby W. F., Wogan G. N. Aflatoxins. Chemical Carcinogens, 2nd ed., C. E. Searle. American Chemical Society, Washington, D.C. 1985; 945
  • Campbell A. A., Whitaker T. B., Pobland A. E., Dickens J. W., Park D. L. Sampling, sample preparation, and sampling plans for foodstuffs for mycotoxion analysis. Pure Appl. Chem. 1986; 58: 305
  • Stoloff L. Aflatoxin control—past and present. J. Assoc. Off. Anal. Chem. 1980; 63: 1067
  • Cullen J. M., Ruebner B. H., Hseih L. S., Hyde D. M., Hseih D. P. Carcinogenicity of dietary aflatoxin Ml in male Fischer rats compared to aflatoxin B1. Cancer Res. 1987; 47: 1913
  • Groopman J. D., Busby W. F., Donahue P. R., Wogan G. N. Aflatoxins as risk factors for liver cancer: an application of monoclonal antibodies to monitor human exposure. Biochemical and Molecular Epidemiology of Cancer, C. C. Harris. Alan R. Liss, New York 1986; 233
  • National Cancer Office of the Ministry of Public Health, People's Republic of China. Studies on Mortality Rates of Cancer in China. People's Publishing House, Beijing 1980
  • Alpert M. E., Hutt M. S. R., Davidson C. S. Hepatoma in Uganda: a study in geographic pathology. Lancet 1968; 1: 1265
  • Alpert M. E., Hutt M. S. R., Wogan G. N., Davidson C. S. Association between aflatoxin content of food and hepatoma in Uganda. Cancer 1971; 28: 253
  • Campbell T. C., Caedo J. P., Bulatao-Jayme J., Salamat L., Engel R. W. Aflatoxin M1 in human urine. Nature (London) 1970; 227: 403
  • Peers F. G., Gilman G. A., Linsell C. A. Dietary aflatoxins and human liver cancer: a study in Swaziland. Int. J. Cancer 1976; 17: 167
  • Peers F. G., Linsell C. A. Dietary aflatoxins and liver cancer: a population based study in Kenya. Br. J. Cancer 1973; 27: 473
  • Shank R. C., Wogan G. N., Gibson J. B., Nondasuta A. Aflatoxins in market foods and foodstuffs of Thailand and Hong Kong. Food Cosmet. Toxicol. 1972; 10: 61
  • Shank R. C., Gordon J. E., Wogan G. N., Nondasuta A., Subhamani B. Field survey of rural Thailand for ingested aflatoxins. Food Cosmet. Toxicol. 1972; 10: 71
  • Van Rensburg S. J., van der Watt J. J., Purchase I. F. H., Coutinho L. P., Markham R. Primary liver cancer rate and aflatoxin intake in a high cancer area. S. Afr. Med. J. 1974; 48: 2508a
  • Shank R. C. Environmental Cancer, H. F. Kraybill, M. A. Mehlman. John Wiley & Sons, New York 1977; 291
  • Linsell C. A., Peers F. G. Aflatoxin and liver cancer. Trans. R. Soc. Trap. Med. Hyg. 1977; 71: 471
  • Bulatao-Jayme J., Almero E. M., Castro C. A., Jardeleza T. R., Salamat L. A case-control dietary study of primary liver cancer risk from aflatoxin exposure. Int. J. Epidemiol. 1982; 11(2)112
  • Van Rensburg S. J., Cook-Mozaffari P., Van Schalkwyk D. J., Van der Watt J. J., Vincent T. J., Purchase I. F. Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. Br. J. Cancer 1985; 51: 713
  • Peers F., Bosch X., Kaldor J., Linsell A., Pluijmen M. Aflatoxin exposure, hepatitis B virus infection and liver cancer in Swaziland. Int. J. Cancer 1987; 39: 545
  • Autrup H., Bradley K. A., Shamsuddin A. K. M., Wakhisi J., Wasunna A. Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7′-guanyl)-3-hydroxyaflatoxin B, in human urine collected in Murang'a district, Kenya. Carcinogenesis 1983; 4(9)1193
  • Autrup H., Seremet T., Wakhisi J., Wasunna A. Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya. Cancer Res. 1987; 47: 3430
  • Coulter J. B. S., Suliman G. I., Lamplugh S. M., Mukhtar B. I., Hendrickse R. G. Aflatoxins in liver biopsies from Sudanese children. Am. J. Trap. Med. Hyg. 1986; 35(2)360
  • Wild C. P., Umbenhauer D., Chapot B., Montesano R. Monitoring of individual human exposure to aflatoxins (AF) and N-nitrosamines (NNO) by immunoassays. J. Cell. Biochem. 1986; 30: 171
  • Wild C. P., Pionneau F., Montesano R., Mutiro C. F., Chetsanga C. J. Afaltoxin detected in human breast milk by immunoassay. Int. J. Cancer 1987; 40: 328
  • Zhu J.-Q., Zhang L.-S., Hu X., Xiao Y., Chen J.-S., Xu Y.-C., Fremy J., Chu F. S. Correlation of dietary aflatoxin B, levels with excretion of aflatoxin M, in human urine. Cancer Res. 1987; 47: 1848
  • Yeh F.-S., Mo C.-C., Yen R.-C. Risk factors for hepatocellular carcinoma in Guangxi, People's Republic of China. Nat. Cancer Inst. Monogr. 1985; 69: 47
  • Tsuboi S., Nakagawa T., Tomita M., Soo T., Ono H., Kawamura K., Iwamura N. Detection of aflatoxin B1 in serum samples of male Japanese subjects by radioimmunoassay and high-peformance liquid chromatography. Cancer Res., 44: 1231
  • Sun T. T., Chu Y.-R., Hsia C.-C., Wei Y.-P., Wu S.-M. Strategies and current trends of etiologic prevention of liver cancer. Biochemical and Molecular Epidemiology, C. C. Harris. Alan R. Liss, New York 1986; 283
  • Essigmann J. M., Croy R. G., Nadzan A. M., Busby W. F., Jr., Reinhold V. N., Buchi G., Wogan G. N. Structural identification of the major DNA adduct formed by aflatoxin B1in vitro. Proc. Natl. Acad. Sci. USA 1977; 74: 1870
  • Croy R. G., Essigmann J. M., Reinhold V. N., Wogan G. N. Identification of the principle aflatoxin B1-DNA adduct formedin vivo in rat liver. Proc. Natl. Acad. Sci. USA 1978; 75: 1745
  • Groopman J. D., Busby W. F., Jr., Wogan G. N. Nuclear distribution of aflatoxin B1 and its interaction with histones in rat liverin vivo. Cancer Res. 1980; 40: 4343
  • Lin J. K., Miller J. A., Miller E. C. 2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or-ribosomal RNA adducts formed in hepatic microsome mediated reactions in rat liverin vivo. Cancer Res. 1977; 37: 4430
  • Hertzog P. J., Lindsay Smith J. R., Garner R. C. Production of monoclonal antibodies to guanine imidazole ring-opened aflatoxin B1-DNA, the persistent DNA adduct in vivo. Carcinogenesis 1982; 3: 723
  • Gopalan C., Tulpule P. G., Krishnamurthi D. Induction of hepatic carcinoma with aflatoxin in Rhesus monkey. Food Cosmet. Toxicol. 1972; 10: 519
  • Adamson R. H., Correa P., Oalgard D. W. Brief communication: occurrence of a primary liver carcinoma in a Rhesus monkey fed aflatoxin B1. J. Natl. Cancer Inst. 1973; 50: 549
  • Tilak T. B. G. Induction of cholangiosarcoma following treatment of a Rhesus monkey with aflatoxin. Food Cosmet. Toxicol. 1975; 13: 247
  • Sieber S. M., Correa P., Dalgard D. W., Adamson R. H. Introduction of ostrogenic sarcomas and tumors of the hepatobiliary system in non-human primates with aflatoxin B1. Cancer Res. 1979; 39: 4545
  • Groopman J. D., Kensler T. W. The use of monoclonal antibody affinity columns for assessing DNA damage and repair following exposure to aflatoxin B1. Pharmacol. Ther. 1987; 34: 321
  • McLean A. E. M., Marshall A. Reduced carcinogenic effects of aflatoxin in rats given phenobarbitone. Br. J. Exp. Pathol 1971; 52: 322
  • Gurtoo H. L., Koser P. L., Bansal S. K., Fox H. W., Sharma S. D., Mulhern A. I., Pavelic Z. P. Inhibition of aflatoxin B1-hepatocarcinogenesis in rats by B-napthoflavone. Carcinogenesis 1985; 6: 675
  • Wong J. J., Hsieh D. P. H. Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential. Proc. Natl. Acad. Sci. USA 1976; 73: 2241
  • Gurtoo H. L., Dahms R. P., Paigen B. Metabolic activation of aflatoxins related to their mutagenicity. Biochem. Biophys. Res. Commun. 1975; 61: 735
  • Cabral J. R. P., Neal G. E. The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats. Cancer Lett. 1983; 9: 125
  • Williams G. M., Tanaka T., Maeura Y. Dose-dependent inhibition of aflatoxin B1 induced-hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxytoluene and butylated hydroxyanisole. Carcinogenesis 1986; 7: 1043
  • DeLong M. J., Prochaska H. J., Talalay P. Inactivate electrophilic compounds. Protective Agents in Human and Experimental Cancer, D. C. McBrien, T. F. Slater. Academic Press, London, 175
  • Kensler T. W., Egner P. A., Davidson N. E., Roebuck B. D., Pikul A., Groopman J. D. Modulation of aflatoxin metabolism, aflatoxinN7-guanine formation and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases. Cancer Res. 1986; 46: 3924
  • Kensler T. W., Enger P. A., Trush M. A., Bueding E., Groopman J. D. Modification of aflatoxin B1 binding to DNAin vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione. Carcinogenesis 1985; 6: 759
  • Croy R. G., Wogan G. N. Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1. Cancer Res. 1981; 41: 197
  • Sabbioni G., Skipper P., Buchi G., Tannenbaum S. R. Isolation and characterization of the major serum albumin adduct formed by aflatoxin B,in vivo in rats. Carcinogenesis 1987; 8: 819
  • Wild C. P., Garner R. G., Montesano R., Tursi F. Aflatoxin B1 binding to plasma albumin and liver DNA upon chronic administration to rats. Carcinogensis 1986; 7: 853
  • Donahue P. R., Essigmann J. M., Wogan G. N. Aflatoxin-DNA adducts: detection in urine as a dosimeter of exposure. Banbury Rep. 1982; 13: 221
  • Haugen A., Groopman J. D., Hsu I. C., Goodrich G. R., Wogan G. N., Harris C. C. Monoclonal antibody to aflatoxin B1 modified DNA detected by enzyme immunoassay. Proc. Natl. Acad. Sci. USA 1981; 78: 4124
  • Groopman J. D., Haugen A., Goodrich G. R., Harris C. C. Quantitation of aflatoxin B1 modified DNA using monoclonal antibodies. Cancer Res. 1982; 42: 3120
  • Groopman J. D., Trudel L. J., Donahue P. R., Rothstein A., Wogan G. N. High affinity monoclonal antibodies for aflatoxins and their application to solid phase immunoassay. Proc. Natl. Acad. Sci. USA 1984; 81: 7728
  • Pestka J. J., Chu F. S. Reactivity of aflatoxin B2a antibody with aflatoxin B1-modified DNA and related metabolites. Appl. Environ. Microbiol 1982; 44: 1159
  • Sun T. T., Chu Y. Y. Carcinogenesis and prevention strategy of liver cancer in areas of prevalence. J. Cell. Physiol. Suppl. 1984; 3: 39
  • Bennett R. A., Essigmann J. M., Wogan G. N. Excretion of an aflatoxin-guanine adduct in urine of aflatoxin B1-treated rats. Cancer Res. 1981; 41: 650
  • Groopman J. D., Donahue P. R., Zhu J., Chen J., Wogan G. N. Aflatoxin metabolism in humans: detection of metabolites and nucleic acid adducts in urine by affinity chromatography. Proc. Natl. Acad. Sci. USA 1985; 82: 6492
  • Groopman J. D., Donahue P. R., Zhu J., Chen J., Wogan G. N. Temporal patterns of aflatoxin metabolites in urine of people living in Guangxi Province, PRC. Proc. Am. Assoc. Cancer Res. 1987; 28: 36

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.