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Research Article

Physical Studies on DNA From “Primitive” Eucaryote

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Pages 349-449 | Published online: 26 Sep 2008

References

  • Cairns J. The bacterial chromosome and its manner of replication as seen by autoradiograph. J. Mol. Biol. 1963; 6: 208
  • Wake R. G. Circularity of the Bacillus sub tilis chromosome and further studies on its bidirectional replicatio. J. Mol. Biol. 1973; 77: 569
  • Kavenoff R., Zimm B. H. Chromosome-sized DNA molecules from Drosophil. Chromosoma 1973; 41: 1
  • Flory P. J. Principles of Polymer Chemistry, 7th ed. Cornell University Press, Ithaca 1953
  • Tanford C. Physical Chemistry ofMacromolecules, 4th ed. John Wiley & Sons, New York 1961
  • Van Holde K. E. Physical Biochemistry. Prentice-Hall, Englewood Cliffs 1971
  • Van Holde K. E., Baldwin R. L. Rapid attainment of sedimentation equilibriu. J. Phys. Chem. 1958; 62: 734
  • Harpst J. A., Krasna A. I., Zimm B. H. Low angle light scattering measurements on native DNA, Fe. Proc. 1965; 24: 538
  • Massie H. R., Zimm B. H. Molecular weight of the DNA in the chromosomes of E. coli and B. subtilis, Proc. Nat. Acad. Sci. U.S.A. 1972; 69(5)1188
  • Klotz L. C., Zimm B. H. Size of DNA determined by viscoelastic measurements: results on bacteriophages Bacillus subtilis and Escherichia col. J. Mol. Biol. 1972; 72: 779
  • Petes T. D., Fangman W. L. Sedimentation properties of yeast chromosomal DN. Proc. Natl. Acad. Sci. U.S.A. 1972; 69: 1188
  • Roberts T., Klotz L. C. Unpublished observations.
  • Lauer G. D., Klotz L. C. Determination of the molecular weight of Sacchararomyces cerevisiae nuclear DN. J. Mol. Biol. 1975; 95: 309
  • Bloomfield V. A. Hydrodynamic properties of DN. Macromolecular Reviews, A. Peterlin, et al. Interscience, New York 1968; 3: 255
  • Kavenoff R. Characterization of the Bacillus subtilis W23 genome by sedimentatio. J. Mol. Biol. 1972; 72: 801
  • Appelby D. W., Rail S. C., Hearst J. E. The S20,w of unsheared DNA from whole cell lysates o. Escherichia coli, Biophys. Chem., in press.
  • Crothers D. M., Zimm B. H. Viscosity and sedimentation of the DNA from bacteriophages T2 and T7 and the relation to molecular weigh. J. Mol. Biol. 1965; 12: 525
  • Leighton S. B., Rubenstein I. Calibration of molecular weight scales for DN. J. Mol. Biol. 1969; 46: 313
  • Ross P. D., Scruggs R. L. Viscosity study of DNA. II. The effect of simple salt concentration on the viscosity of high molecular weight DNA and application of viscometry to the study of DNA isolated from T4 and T5 bacteriophage mutant. Biopolymers 1968; 6: 1005
  • Freifelder D. Molecular weights of coliphages and coliphage DNA. IV. Molecular weights of DNA from bacteriophages T4, T5, and T7 and the general problem of determination of . J. Mol. Biol. 1970; 54: 567
  • Gill S. J., Thompson D. S. A rotating Cartesian-diver viscomete. Proc. Natl. Acad. Sci. U.S.A. 1967; 57: 3
  • Zimm B. H., Crothers D. M. Simplified rotating cylinder viscometer for DN. Proc. Natl. Acad. Sci. U.S.A. 1962; 48: 905
  • Chapman R. E., Jr., Klotz L. C., Thompson D. S., Zimm B. H. An instrument for measuring retardation times of deoxyribonucleic acid solution. Macromolecules 1969; 2: 6
  • Thompson D. S., Hays J. B., Gill S. J. Increasing viscosity of E. coli chromatin with increasing shea. Biopolymers 1969; 7: 571
  • Klotz L. C., Zimm B. H. Unpublished observations.
  • Bloomfield V., Zimm B. H. Viscosity, sedimentation et cetera, of ring and straight-chain polymers in dilute solutio. J. Chem. Phys. 1966; 44: 315
  • Douthart R. J., Bloomfield V. A. Intrinsic viscosities of cyclic and linear γ. DNA, Biopolymers 1968; 6: 1297
  • Rosenberg A. H., Studier F. W. Intrinsic viscosity of native and single stranded T7 DNA and its relationship to sedimentation coefficien. Biopolymers 1969; 7: 765
  • Uhlenhopp E. L., Zimm B. H. Viscoelastic characterization of single-stranded DNA fro. E. coli, Biophys. J. 1975; 15: 223
  • Zimm B. H. Dynamics of polymer molecules in dilute solution: viscoelasticity, flow birefringence and dielectric tos. J. Chem. Phys. 1956; 24: 269
  • Klotz L. C., Zimm B. H. Retardation times of macro deoxyribonucleic acid solutions. II. Improvements in apparatus and theor. Macromolecules 1972; 5: 471
  • Muller W. A., Klotz L. C. Retardation time measurements on replicating Bacillus subtilis chromosomes: effects of EDTA concentratio. Biochim. Biophys. Acta 1975; 378: 171
  • Thompson D. S., Gill S. J. Polymer relaxation times from birefringence relaxation measurement. J. Chem. Phys. 1967; 47: 5008
  • Callis P. R., Davidson N. Hydrodynamic relaxation times of DNA from decay of flow dichroism measurement. Biopolymers 1969; 8: 379
  • Gillis M., de Ley J., de Cleene M. The determination of molecular weight of bacterial genome DNA from renaturation rate. Eur. J. Biochem. 1970; 12: 143
  • Massa D. J. Flow properties of high molecular-weight DNA solutions: viscosity, recoil, and longest retardation tim. Biopolymers 1973; 12: 1071
  • Blamire J., Cryer D. R., Finkelstein D. B., Marmur J. Sedimentation properties of yeast nuclear and mitochondrial DN. J. Mol. Biol. 1972; 67: 11
  • Uhlenhopp E. L., Zimm B. H., Cummings D. J. Structural aberrations in T-even bacteriophage. VI. Molecular weight of DNA from giant head. J. Mol. Biol. 1974; 89: 689
  • Bowen B. Unpublished observation.
  • Shafer R. H. Radial migration of DNA molecules in cylindrical flow. II. The non-draining model and possible application to fractionatio. Biophys. Chem. 1974; 2: 185
  • Uhlenhopp E. L. Viscoelastic analysis of high molecular weight, alkali-denatured DNA from mouse 3T3 cell. Biophys. J. 1975; 15: 233
  • Studier F. W. Sedimentation studies of the size and shape of DN. J. Mol Biol. 1965; 11: 373
  • Rosenbloom J., Schumaker V. N. Analytical ultracentrifugation of T4R bacteriophage DNA in preformed sucrose density gradient. Biochemistry 1963; 2: 1206
  • Shumaker V. N., Zimm B. H. Anomalies in sedimentation. II. Biopolymers 1973; 12: 877
  • Burgi E., Hershey A. D. Sedimentation rate as a measure of molecular weight of DN. Biophys. J. 1963; 3: 309
  • Rubenstein I., Leighton S. B. The influence of rotor speed on the sedimentation behavior in sucrose gradients of high molecular weight DNA's, Biophy. Soc. Annu. Meet. Abstr. 1971; 11: 209a
  • Zimm B. H. Anomalies in sedimentation. IV. Decrease in sedimentation coefficients of chains at high field. Biophys. Chem. 1974; 1: 279
  • Bloomfield V. A. Sedimentation coefficients of replicating and cross-linked DN. Biopolymers 1968; 6: 285
  • Nomura M., Hall B. P., Spiegelman S. Characterization of RNA synthesized in Escherichia coli after bacteriophage T2 infectio. J. Mol. Biol. 1960; 2: 306
  • McGrath R. A., Williams R. W. Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken piece. Nature 1966; 212: 534
  • McGrath R. A., Williams R. W. Interruptions in single strands of the DNA in slime mole and other organism. Biophys. J. 1967; 7: 309
  • McBurney M. W., Graham F. L., Whitmore G. F. Anomalous sedimentation of high molecular weight denatured mammalian DN. Biochem. Biophys. Res. Commun. 1971; 44: 1
  • Huberman J. A., Riggs A. D. Autoradiography of chromosomal DNA fibers from Chinese hamster cell. Proc. Natl. Acad. Sci. U.S.A. 1966; 55: 599
  • Worcel A., Burgi E. On the structure of the folded chromosome of Escherichia col. J. Mol. Biol. 1972; 71: 127
  • Kleinschmidt A., Zahn R. K., et al. Uber des Oxyribonucleinsaüre-molekeln in Protein-mischfilme. Z. Naturjorsch. Teil A 1959; 14: 770
  • Kleinschmidt A. K. Monolayer techniques on electron microscopy of nucleic acid molecule. Methods in Enzymology, L. Grossman, K. Moldave. Academic Press, New York 1968; 12: 361, Part B
  • Younghusband H. B., Inman R. B. The electronmicroscopy of DN. Annu. Rev. Biochem. 1974; 43: 605
  • Davis R. W., Simon M., Davidson N. Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acid. Methods in Enzymology, L. Grossman, K. Moldave. Academic Press, New York 1971; 21: 413, Part D
  • Lang D., Kleinschmidt A. K., Zahn R. K. Konfiguration unde Langenverteilung von DNA-molekülen in Lösun. Biochim. Biophys. Acta 1964; 88: 142
  • Kavenoff R., Klotz L. C., Zimm B. H. On the nature of chromosome-sized DNA molecule. Cold Spring Harbor Symp. Quant. Biol. 1973; 38: 1
  • Lark K. G., Consigli R., Toliver A. DNA replication in Chinese hamster cells: evidence for a single replication fork per replico. J. Mol. Biol. 1971; 58: 873
  • Burton K. Determination of DNA concentration with diphenylamin. Methods in Enzymology, L. Grossman, K. Moldave. Academic Press, New York 1968; 12: 163, Part B
  • Kissane J. M., Robins E. The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous syste. J. Biol. Chem. 1958; 233: 184
  • LePecq J. B., Paoletti C. A new fluorometric method for RNA and DNA determinatio. Anal. Biochem. 1966; 17: 100
  • Marmur J. A procedure for the isolation of deoxyribonucleic acid from micro-organism. J. Mol. Biol. 1961; 3: 208
  • Britten R. J., Pavich M., Smith J. A new method for DNA purification. Carnegie Inst., Washington Yearb 1968; 400
  • Wetmur J. G. Hybridization and renaturation kinetics of nucleic acid. Annu. Rev. Biophys. Bioeng., in press.
  • Britten R. J., Graham D. E., Neufeld B. R. Analysis of repeating DNA sequences by reassociatio. Methods in Enzymology, L. Grossman, K. Moldave. Academic Press, New York 1974; Vol. 29, Part E: 363
  • Rau D. C., Ph.D. Thesis. Harvard University, Cambridge 1975
  • Rau D. C., Klotz L. C. Unpublished observations.
  • Wetmur J. G., Davidson N. Kinetics of renaturation of DN. J. Mol. Biol. 1968; 31: 349
  • Wetmur J. G., Ph.D. Thesis. California Institute of Technology, Pasadena 1967
  • Britten R. J., Smith M. J., Davidson E. H. Experimental studies on nucleic acid reassociation kinetics. I. Rate of duplex formation in DNA-DNA reaction. J. Mol. Biol., submitted.
  • Morrow J., Ph.D. Thesis. Stanford University, Stanford 1974
  • Miller S. J., Wetmur J. G. Physical properties of endonuclease SI digestion products of DNA renaturation intermediate. Biopolymers 1975; 14: 309
  • Rau D. C., Klotz L. C. A more complete kinetic theory of DNA renaturatio. J. Chem. Phys. 1975; 62: 2354
  • Cold Spring Harbor Symposium on Quantitative Biology, V. XXXVIII, 1973, L. Frisch, J. Cairns, Long Island 1974
  • Delange R. J., Fambrough D. M., Smith E. L., Bonner J. Calf and pea histone IV. II. The complete amino acid sequence of calf thymus histone IV; presence of c-N-acetylysin. J. Biol. Chem. 1969; 244: 319
  • Delange R. J., Fambrough D. M., Smith E. L., Bonner J. Calf and pea histone IV. III. Complete amino acid sequence of pea seedling histone IV; comparison with the homologous calf thymus histon. J. Biol. Chem. 1969; 244: 5669
  • Ogawa Y., Qualiarotti G., Jordan J., Taylor C. W., Starbuck W. C., Busch H. Structural analysis of the glycine-rich, arginine-rich histon. J. Biol. Chem. 1969; 244: 4387
  • Elgin S. C. R., Weintraub H. Chromosomal proteins and chromatin structur. Annu. Rev. Biochem. 1975; 44: 725
  • Felsenfeld G. String of pearl. Nature 1975; 257: 177
  • Olins A. L., Olins D. E. Spheroid chromatin units (v bodies. Science 1974; 183: 330
  • Kornberg R. D. Chromatin structure: a repeating unit of histones and DN. Science 1974; 184: 868
  • Hewesh D. R., Burgoyne L. A. Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonucleas. Biochem. Biophys. Res. Commun. 1973; 52: 504
  • McGhee J. D., Engle J. D. Subunit structure of chromatin is the same in plants and animal. Nature 1975; 254: 449
  • Davidson E. H., Galau G. A., Angerer R. C., Britten R. J. Comparative aspects of DNA organization in metazo. Chromosoma 1975; 51: 253
  • Davidson E. H., Hough B. R., Klein W. H., Britten R. J. Structural genes adjacent to interspersed repetitive DNA sequence. Cell 1975; 4: 217
  • Manning J. E., Schmid C. W., Davidson N. Interspersion of repetitive and nonrepetitive DNA sequences in the Drosophila melanogaster genom. Cell 1975; 4: 141
  • Flavell R. B., Bennett M. D., Smith J. B., Smith D. B. Genome size and the proportion of repeated nucleotide sequence DNA in plant. Biochem. Genet. 1974; 12: 257
  • Klein A., Bonhoeffer F. DNA replicatio. Annu. Rev. Bfochem. 1972; 41: 301
  • Cairns J. Autoradiography of HeLa cell DN. J. Mol. Biol. 1966; 15: 372
  • Huberman J. A., Riggs A. D. On the mechanism of DNA replication in mammalian chromosome. J. Mol. Biol. 1968; 32: 327
  • Callan H. C. Replication of DNA in the chromosomes of eukaryote. Proc. R. Soc. London Ser. B 1972; 181: 19
  • Blumenthal A. B., Kriegstein H. J., Hogness D. S. The units of DNA replication in Drosophila melanogaster chromosomes, Cold Spring Harbor Sym. Quant. Biol. 1973; 38: 205
  • Callan J. G. DNA replication in the chromosomes of eukaryote. Cold Spring Harbor Symp. Quant. Biol. 1973; 38: 195
  • Wilson D. A., Thomas C. A., Jr. Palindromes in chromosome. J. Mol. Biol. 1974; 84: 115
  • Davidson E. H., Graham D. E., Neufeld B. R., Chamberlin M. E., Amenson C. S., Hough B. R., Britten R. J. Arrangement and characterization of repetitive sequence elements in animal DNA. Cold Spring Harbor Symp. Quant. Biol. 1973; 38: 295
  • Schmid C. W., Manning J. E., Davidson N. Inverted repeat sequences in the Drosophila genom. Cell 1975; 5: 159
  • Loeblich A. R., Jr. Protistan phylogeny as indicated by the fossil recor. Taxon 1974; 23: 277
  • Dixon P. S. Biology of the R hodophyta. Macmillan 1973
  • Nasatir M., Brooks A. E. DNA of the marine red alga Griffithsia globulifer. J. Phycol 1966; 2: 144
  • Muller W. A., Klotz L. C. Unpublished observations.
  • Ramus J. The production of extracellular polysaccharide by the unicellular red alga Porphyridium aerugineu. J. Phycol. 1972; 8: 97
  • Howland G. P., Ramus J. Analysis of blue-green and red algal ribosomal RNA's by gel electrophoresi. Arch. Mikrobiol., 76: 292–197
  • Bonen L., Doolittle W. F. On the prokaryotic nature of red algal chloroplast. Proc. Natl. Acad. Sci. U.S.A. 1975; 72: 2310
  • Sanger F., Brownlee G. G., Barrell B. G. A two-dimensional fractionation procedure for radioactive nucleotide. J. Mol. Biol. 1965; 13: 373
  • Uchida T., Bonen L., Schaup H. W., Lewis B. J., Zablen L., Woese C. The use of ribonuclease U2 in RNA sequence determination: Some corrections in the catalog of oligomers produced by ribonuclease T1 digestions of Escherichia coli, 16S ribosomal RN. J. Mol. Evol. 1974; 3: 63
  • Uzzel T., Spolsky C. Mitochondria and plastids as endosymbionts: a revival of special creatio. Am. Sci. 1974; 62: 334
  • Bogorad L. Evolution of organelles and eukaryotic genome. Science 1975; 188: 891
  • Cavalier-Smith T. The origin of nuclei and eukaryotic cell. Nature 1975; 256: 463
  • Allen J. R., Roberts T. M., Loeblich A. R., III, Klotz L. C. Characterization of the DNA from the dinoflagellate Crypthecodinium cohnii and implications for nuclear organizatio. Cell 1975; 6: 161
  • Holm-Hansen O. Algae: Amounts of DNA and organic carbon in single cell. Science 1969; 163: 87
  • Dodge J. D. The Dinophycea. The Chromosomes of Algae, M. B. E. Godward. St. Martin's Press, New York 1966; 96
  • Loeblich A. R., III. Dinoflagellate evolution: Speculation and evidenc. J. Protozool. 1976; 5: 23
  • Giesbrecht P. Vergleichende Untersuchungen an der Chromosomen des Dinoflagellaten Amphidinium elegans und der Bakterien, Zentralbl. Bakteriol Parasitenkd. Infeklionsk. Hyg. Abt. I Orig. 1962; 187: 452
  • Dodge J. D. Chromosome structure in the Dinophyceae. II. Cytochemical studie. Arch. Mikrobiol. 1964; 48: 66
  • Rizzo P. J., Nooden L. D. Isolation and partial characterization of dinoflagellate chromosomal protein. Biochim. Biophys. Acta 1974; 349: 402
  • Rizzo P. J., Nooden L. D. Partial characterization of dinoflagellate chromosomal protein. Biochim. Biophys. Acta 1974; 349: 415
  • Kubai D. F., Ris H. Division in the dinoflagellate Gyrodinium cohnii (Schiller). A new type of nuclear reproductio. J. Cell Biol. 1969; 40: 508
  • Dodge J. D. Chromosome structure in the dinoflagellates and the problem of the mesocaryotic cel. Excerpta Med. Intl. Congr. Ser. 1965; 91: 339
  • Giesbrecht P. Über das Ordungsprinzp in den Chromosomen von Dinoflagellaten und Bakterien, Zentralbl Bakteriol. Parasitenkd. lnfeklionsk. Hyg. Abt. I Orig. 1965; 196: 516
  • Grassé M. P.P., Hollande A., Cachon J., Cachon-Enjumet M. Nouvelle interpretation de Infrastructure du chromosome de certains Peridinien. Cytologic 1965; 12: 1
  • Bouligand Y., Soyer M.-O., Puiseux-Dao S. La structure fibrillaire et l'orientation des chromosomes chez Dinoflagelle. Chromosoma 1968; 24: 251
  • Lerman L. S. Chromosomal analogues: Long-range order in ϕ-condensed DNA, Cold Spring Harbor Sym. Quant. Biol. 1973; 38: 295
  • Haapala O. K., Soyer M. Structure of dinoflagellate chromosome. Nat. New Biol. 1973; 244: 195
  • Soyer M. O., Haapala O. K. Structural changes of dinoflagellate chromosomes by pronase and ribonucleas. Chromosoma 1974; 47: 179
  • Soyer M. O., Haapala O. K. Division and function of dinoflagellate chromosome. J. Microsc. (Paris) 1974; 19: 137
  • Haapala O.-K., Soyer M. O. Size of circular chromatids and amount of haploid DNA in the dinoflagellates Gyrodinium cohnii and Procentrum mican. Hereditas 1974; 76: 83
  • Franker C. K. Some properties of DNA from the Zooranthellae harbored by an anemone Anthopkura elegantissim. J. Phycol. 1970; 6: 299
  • Franker C. K., Sakhrani L. M., Prichard C. D., Lambden C. A. DNA synthesis in Crypthecodinium cohni. J. Phycol. 1974; 10: 91
  • Rae P. M. 5-hydroxymethyluracil in DNA of a dinoflagellat. Proc. Natl. Acad. Sci., U.S.A. 1973; 70: 1141
  • Roberts T. M., Tuttle R. C., Allen J. R., Loeblich A. R., III, Klotz L. C. New genetic and physiochemical data on the structure of dinoflagellate chromosome. Nature 1974; 248: 246
  • Tuttle R. C., Loeblich A. R., III. Genetic recombination in the dinoflagellat. Crypthecodinium cohnii, Science 1974; 185: 1061
  • Ryan R. S., Grant D., Chiang K. S., Swift H. Isolation of mitochondria and characterization of the mitochondrial DNA of Chlamydomonas reinhardti. J. Cell Biol. 1973; 59: 297a
  • Gillham N. W. Genetic analysis of the chloroplast and mitochondrial genome. Annu. Rev. Genet. 1974; 8: 347
  • Borst P. Mitochondrial nucleic acid. Annu. Rev. Biochem. 1972; 41: 333
  • Bastia D., Chiang K. S., Swift H., Siersma P. Heterogeneity, complexity, and repetition of the chloroplast DNA of Chlamydomonas reinhardtii, Pro. Natl. Acad. Sci., U.S.A. 1971; 68: 1157
  • Wells R., Sager R. Denaturation and renaturation kinetics of chloroplast DNA from Chlamydomonas reinhard. J. Mol. Biol. 1971; 58: 611
  • Howell S. H., Walker L. L. Informational complexity of the nuclear and chloroplast genomes of Chlamydomonas reinhard. Biochim. Biophys. Acta, in press.
  • Bayen M., Rode A. Heterogeneity and complexity of Chlorella chloroplastic DN. Eur. J. Biochem. 1974; 39: 413
  • Rau D. C., Klotz L. C., in preparation.
  • Thomas J. R., Tewari K. K. Conservation of 70S ribosomal RNA genes in the chloroplast DNAs of higher plant. Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 3147
  • Hermann R. G., Bohnert H.-J., Kowallik K. V., Schmitt J. M. Size, conformation and purity of chloroplast DNA of some higher plant. Biochim. Biophys. Acta 1975; 378: 305
  • Manning J. E., Richards O. C. Isolation and molecular weight of circular chloroplast DNA from Euglena gracilis, Biochi. Biophys. Acta 1972; 259: 285
  • Stutz E. The kinetic complexity of Euglena gracilis chloroplasts DN. FEBS Lett. 1970; 8: 25
  • Gilles M., DeLey J., DeCleene M. The determination of molecular weight of bacterial genome DNA from renaturation rate. Eur. J. Biochem. 1970; 12: 143
  • Slavick N. S., Hershberger C. L. The kinetic complexity of Euglena gracilis chloroplast DN. FEBS Lett. 1975; 52: 171
  • Chiang K.-S., Sueoka N. Replication of chromosomal and cytoplasmic DNA during mitosis and meiosis in the eucaryote Chlamydomonas reinhard. J. Cell. Physiol 1970; 89(Suppl. 1)167
  • Chiang K. S., Sueoka N. Replication of chloroplast DNA in Chlamydomonas reinhardi during vegetative cell cycle: its mode and regulatio. Proc. Natl. Acad. Sci. U.S.A. 1967; 57: 1506
  • Lwai K. Histones of rice embryos and of Chlorella, in 77ie Nucleohistones, J. Bonner, P. Ts'o. Holden-Day, San Francisco 1964; 59
  • Bradley D. M. Histone analysis i. Volvox, FEBS Lett. 1974; 41: 219
  • Blamire J., Flechtner V. R., Sager R. Regulation of nuclear DNA replication by the chloroplast i. Chlamydomonas, Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 2867
  • Chiang K. S., Eves E., Swinton D. Variation of thymidine incorporation patterns in the alternating vegetative and sexual life cycles o. Chlamydomonas reinhardtii, Dev. Biol. 1975; 42: 53
  • Gillham N. W. Genetic analysis of the chloroplast and mitochondrial genome. Annu. Rev. Genet. 1974; 8: 347
  • Sager R. Cytoplasmic Genes and Organelles. Academic Press, New York 1972
  • Sueoka N., Chiang K. S., Kates J. R. Deoxyribonucleic acid replication in meiosis of Chlamydomonas reinhardi. I. Isotopic transfer experiments with a strain producing eight zoospore. J. Mol Biol. 1967; 25: 47
  • Bayen M., Dalmon J. Determination physico-chemique de la ploidie chez l'algue unicellulaire Chlorella pyrenoidosa (souche 211/8b. Biochim. Biophys. Acta 1975; 395: 213
  • Siu C. H., Chiang K. S., Swift H. Characterization of cytoplasmic and nuclear genomes in the colorless alga Polytoma. IV. Heterogeneity and complexity of the nuclear genom. Chromosoma 1974; 48: 19
  • Miller O. L., Beatty B. R. Visualization of nucleolar gene. Science 1969; 164: 955
  • Miller O. L., Beatty B. R. Extrachromosomal nucleolar genes in amphibian oocyte. Genetics Suppl 1969; 61: 134
  • Miller O. L., Beatty B. R. Portrait of a gen. J. Cell Physiol. 1969c; 74(Suppl. 1)225
  • Kloppstech K., Berger S., Schweiger H. G. Distribution and transportation of cytosol ribosomes in Acetabularia majo. J. Cell Biol. 1974; 63: 173a
  • Trendelenburg M. J., Spring H., Scheer U., Franke W. W. Morphology of nucleolar cistrons in a plant cel. Acetabularia mediterranea, Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 3626
  • Woodcock C. L. F., Stanchfield J. E., Gould R. R. Morphology and size of ribosomal cistrons in two plant species: Acetabularia mediterranea and Chlamydomonas reinhard. Plant Sci. Lett. 1975; 4: 17
  • Berger S., Schweiger M. G. Ribosomal DNA in different members of a family of green algae (Chlorophyta dasycladaceae): an electron microscipal stud. Planta, in press.
  • Berger S., Schweiger H. G. An apparent lack of nontranscribed spacers in rDNA in a green alg. Mol. Gen. Genet. 1975; 139: 269
  • Parenti J., Brawerman G., Preston J. F., Eisenstadt J. M. Isolation of nuclei from Euglena gracilis, Biochi. Biophys. Acta 1969; 195: 234
  • Leedale G. F. Mitosis and chromosome numbers in th. Euglenindae (Flagellata), Nature 1958; 181: 502
  • Netrawali M. S. On the presence of histones in Euglena gracilis var. bacillarus, Ex. Celi. Res. 1970; 63: 422
  • Manning J. E., Wolstenholme D. R., Ryan R. S., Hunter J. A., Richards O. C. Circular chloropiast DNA from Euglena gracilis, Proc Nat. Acad. Sci. U.S.A. 1971; 68: 1169
  • Nass M. M. K., Schori L., Ben-Shaul Y., Edelman M. Size and configuration of mitochondrial DNA in Euglena gracilis, Biochi. Biophys. Acta 1974; 374: 283
  • Talen J. L., Sanders J. P. M., Flavell R. A. Genetic complexity of mitochondrial DNA from Euglena gracilis, Biochi. Biophys. Acta 1974; 374: 129
  • Crouse E. J., Vandrey J. P., Stutz E. Hybridization studies with RNA and DNA isolated from Euglena gracilis chloroplasts and mitochondri. FEBS Lett. 1974; 42: 262
  • Fonty G., Crouse E. J., Stutz E., Bernardi G. The mitochondrial genome of Euglena gracilis, Eu. J. Biochem. 1975; 54: 367
  • Ray D. S., Hanawalt P. C. Satellite components in Euglena gracilis cells lacking chloroplast. J. Mol. Biol. 1965; 11: 760
  • Edelman M., Schiff J. A., Epstein H. T. Studies of chloropiast development in Euglena. XII. Two types of satellite DN. J. Mol. Biol. 1965; 11: 769
  • Brawerman G., Eisenstadt J. M. Deoxyribonucleic acid from the chloroplasts of Euglena gracilis, Biochi. Biophys. Acta 1964; 91: 477
  • Edelman M., Cowan C. A., Epstein H. T., Schiff J. A. Studies of chloropiast development in Euglena VIII. Chloropiast associated DNA, Pro. Natl. Acad. Sci. U.S.A. 1964; 52: 1214
  • Ray D. S., Hanawalt P. C. Properties of the satellite DNA associated with the chloroplasts of Euglena gracili. J. Mol. Biol. 1964; 9: 812
  • Rawson J. R. Y., Haselkorn R. Chloropiast ribosomal RNA genes in the chloropiast DNA of Euglena gracili. J. Mol. Biol. 1973; 77: 125
  • Stutz E., Vandrey J. P. Ribosomal DNA satellite of Euglena gracilis chloropiast DN. FEBS Lett. 1971; 17: 277
  • Scott N. S. Ribosomal RNA cistrons in Euglena gracili. J. Mol. Biol. 1973; 81: 327
  • Thomas J. R., Tewari K. K. Conservation of 70S ribosomal RNA genes in the chloropiast DNAs of higher plant. Proc. Natl. Acad. Sci. U.S.A. 1974; 71: 3147
  • Vandrey J. P., Stutz E. Evidence for a novel DNA component in chloroplasts o. Euglena gracilis, FEBS Lett. 1973; 37: 174
  • Zablen L. B., Kissil M. S., Woese C. R., Burton D. E. Phylogenetic origins of the chloropiast and prokaryotic nature of its ribosoma. RNA, Proc. Natl. Acad. Sci. U.S.A. 1975; 72: 2418
  • Rawson J. R. Y. Measurement of the fraction of chloropiast DNA transcribed in Euglena, Bioche. Biophys. Res. Commun. 1975; 62: 539
  • Richards O. C., Ryan R. S., Manning J. E. Effects of cycloheximide and of chloramphenica on DNA synthesis in Euglena gracilis, Biochi. Biophys. Acta 1971; 238: 190
  • Manning J. E., Richards O. C. Synthesis and turnover of Euglena gracilis nuclear and chloropiast deoxyribonucleic aci. Biochemistry 1972; 11: 2036
  • Rawson J. R. Y. The characterization of Euglena gracilis DNA by its reassociation kinetics, Biochi. Biophys. Acta. 1975; 402: 171
  • Mortimer R. K., Hawthorne D. C. Genetic mapping in Saccharomyces. IV. Mapping of temperature-sensitive genes and use of disomic strains in localizing gene. Genetics 1973; 74: 33
  • Linnane A. W., Haslam J. M., Lukins H. B., Nagley P. The biogenesis of mitochondria in microorganism. Annu. Rev. Microbiol. 1972; 26: 163
  • Cryer D. R., Goldthwaite C. D., Zinker S., Lam K. B., Storm E., Hiischberg R., Blamire J., Finkelstein D. B., Marmur J. Studies on nuclear and mitochondrial DNA of Saccharomyces ccrevisiae, Cold Spring Harbor Sym. Quant. Biol. 1973; 38: 17
  • Rubin G. M., Sulston J. E. Physical linkage of the 5s cistrons to the 18s and 28s ribosomal cistrons in Saccharomyces ccrevisia. J. Mol. Biol. 1973; 79: 521
  • Smith I., Dubnau D., Morell P., Marmur J. Chromosomal location of DNA base sequences complementary to transfer RNA and to 5s, 16s, and 23s ribosnmnl RNA in Bacillus subtili. J. Mol. Biol. 1968; 33: 123
  • Wimber D. E., Steffensen D. M. Localization of 5s RNA genes on Drosophila chromosomes by RNA-DNA hybridizatio. Science 1971; 170: 639
  • Pardue M. L. Localization of repeated DNA sequences in Xenopus chromosome. Cold Spring Harbor Symp. Quant. Biol. 1973; 38: 475
  • Pardue M. L., Brown D. D., Bernsteil M. L. Location of the genes for 5s ribosomal RNA in Xenopus laevi. Chromosoma 1973; 42: 191
  • Hartwell L. H., Culotti J., Pringle J. R., Reid B. J. Genetic control of the cell division cycle in yeas. Science 1974; 183: 46
  • Bhargava M. M., Halvorson H. O. Isolation of nuclei from yeas. J. Cell Biol. 1971; 49: 423
  • Smith D., Halvorson H. O. The isolation of DNA from yeas. Methods in Emymology, L. Grossman, K. Moldave. Academic Press, New York 1967; Part A, Vol. 12: 538
  • Bhargava M. M., Cramer J. H., Halvorson H. O. Isolation of high molecular weight DNA from yeast nucle. Anal. Biochem. 1972; 49: 276
  • Moustacchi E., Williamson D. H. Physiological variations in satellite components of yeast DNA detected by density gradient centrifugatio. Biochem. Biophys. Res. Commun. 1966; 23: 56
  • Schildkraut C. L., Marmur J., Doty P. Determination of the base composition of DNA from its buoyant density in cesium chlorid. J. Mol. Biol. 1962; 4: 430
  • Corneo G., Moore C., Sanadi D. R., Grossman L. I., Marmur J. Mitochondrial DNA in yeast and some mammalian specie. Science 1966; 151: 687
  • Cramer J. H., Bhargava M. M., Halvorson H. O. Isolation and characterization of γ DNA of Saccharomyces cerevisia. J. Mol. Biol. 1972; 71: 11
  • Finkelstein D. B., Blamire J., Marmur J. Isolation and fractionation of yeast nucleic acids. I. Characterization of poly(L-lysine) Kieselguhr chromatography using yeast nucleic acid. Biochemistry 1972; 11: 4853
  • Lauer G. D., Klotz L. C., Unpublished observations.
  • Storch R., Mandel M., Schildkraut C. L., Marmur J. Use of CsCl density gradient analysis for determining the guanine plus cytosine content of DN. Methods in Enzymology, L. Grossman, K. Moldave. Academic Press, New York 1968; 12 Part B: 184.
  • Ogur M., Minckler S., Lindegren G., Lindegren C. C. The nucleic acids in a polyploid series of Saccharomyces, Arc. Biochem. Biophys. 1952; 40: 175
  • Ciferri O., Sora S., Tiboni O. Effect of gene dosage on tryptophan synthetase activity in Saccharomyces cerevisia. Genetics 1969; 61: 567
  • Schweizer E., Halvorson H. O. On the regulation of ribosomal RNA synthesis in yeas. Exp. Cell Res. 1969; 56: 239
  • Whitney P. A., Hall B. D. Personal communication.
  • Bicknell J. N., Douglas H. C. Nucleic acid homologies among species of Saccharomyce. J. Bacteriol 1970; 101: 505
  • Hartwell L. H. Saccharomyces cerevisiae cell cycl. Bacteriol. Rev. 1974; 38: 164
  • Whitney P. A., Hall B. D. Repeated DNA in Saccharomyces cerevisiae, Fed. Proc. Fe. Am. Soc. Exp. Biol. 1974; 33: 1282
  • Rubenstein I., Leighton S. B. The influence of rotor speed on the sedimentation behavior in sucrose gradients of high molecular weight DNA's, Biophy. Soc. Annu. Meet. Abstr. 1971; 11: 209a
  • Levin D., Hutchinson F. Neutral sucrose sedimentation of very large DNA from Bacillus subtilis. I. Effect of random double-strand breaks and centrifuge speed on sedimentatio. J. Mol. Biol. 1973; 75: 455
  • Zimm B. H., Schumaker V. N. Anomalies in sedimentation. V. Chains at high fields, practical consequence. Biophys. Chem. Symp., in press.
  • Whitehouse H. L. K. Towards an Understanding of the Mechanism of Heredity, 3rd ed. St. Martin's Press, New York 1967; 86
  • Petes T. D., Byers B., Fangman W. L. Size and structure of yeast chromosomal DN. Proc. Natl Acad. Sci. U.S.A. 1973; 70: 3072
  • Ogur M., Minckler S., McClary D. O. Desoxyribonucleic acid and the budding cycle in the yeast. J. Bacteriol. 1953; 66: 642
  • Williamson D. H., Scopes A. W. The behaviour of nucleic acids in synchronously dividing cultures of Saccharomyces cerevisia. Exp. Cell Res. 1960; 20: 338
  • Williamson D. H. The timing of deoxyribonucleic acid synthesis in the cell cycle of Saccharomyces cerevisia. J. Cell Biol. 1965; 25: 517
  • Williamson D. H., Fennell D. J. Apparent dispersive replication of yeast mitochondrial DNA as revealed by density labelling experiment. Mol. Gen. Genet. 1974; 131: 193
  • Meselson M., Stahl F. W. The replication of DNA in Escherichia coli, Proc. Natl. Aca. Sci. U.S.A. 1958; 44: 671
  • Newlon C. S., Petes T. D., Hereford L. M., Fangman W. L. Replication of yeast chromosomal DN. Nature 1974; 247: 32
  • Petes T. D., Williamson D. H. Über autoradiography of replicating yeast DN. Exp. Cell Res., in press.
  • Cairns J. Synthesis and structure of macromolecule. Cold Spring Harbor Symp. Quant. Biol. 1963; 28: 43
  • Bode H. R., Morowitz H. J. Size and structure of the Mycoplasma hominis H39 chromosom. J. Mol. Biol. 1967; 23: 191
  • Burke W., Newlon C. S., Fangman W. L. Replication initiation in yeast chromosome. The Eukaryote Chromosome, W. J. Peacock, R. D. Brock. Australian National University Press, Canberra 1974
  • Hollfield R., Vielmetter W. Bidirectional growth of the E. coli chromosom. Nat. New Biol. 1973; 242: 130
  • Tamaki H. Chromosome behavior at meiosis in Saccharomyces cerevisia. J. Gen. Microbiol. 1965; 41: 93
  • Robinow C. F. The structure and behavior of the nuclei in spores and growing hyphae of Mucorales. I. Mucor heimalie and Mucor fragilis. Ca. J. Microbiol. 1957; 3: 771
  • Williamson D. H. Nuclear events in synchronously divided yeast culture. Cell Synchrony, I. Cameron, G. Padilla. Academic Press, New York 1966; 81
  • Conti S. F., Naylor H. B. Electron microscopy of ultrathin sections of Schizosaccharomyces octosporus. I. Cell divisio. J. Bacteriol. 1959; 78: 868
  • Thyagarajan T. R., Conti S. F., Naylor H. B. Electron microscopy of Rhodotorula glutini. J. Bacteriol. 1962; 83: 381
  • McClintock B. Neurospora, 1, Preliminary observations of the chromosomes of Neurospora crass. Am. J. Bot. 1945; 32: 671
  • Robinow C. F. The structure and behavior of the nuclei in spores and growing hyphae of Mucorales. II. Phycomyces Blakesleeanus, Ca. J. Microbiol. 1957; 3: 791
  • Robinow C. F. Observations on cell growth, mitosis, and division in the fungus Basidiobolus ranaru. J. Cell Biol. 1963; 17: 123
  • Edwards M. R., Hazen E. L., Edwards G. A. The fine structure of the yeast-like cells of Histoplasma in cultur. J. Gen. Microbiol. 1959; 20: 496
  • Shatkin A. J., Tatum E. L. Electron microscopy of Neurospora crassa Myceli. J. Biophys. Biochem. Cytol. 1959; 6: 423
  • Thyagarajan T. R., Naylor H. B. Cytology of Rhodotorula glutini. J. Bacteriol. 1962; 83: 127
  • Peterson J. B., Ris H. High voltage electron microscopic study of the mitotic spindle in Baker's yeas. J. Cell Biol., 63: 266a–174
  • Wintersberger U., Smith P., Letnansky K. Yeast chromatin, and transcription capacit. Eur. J. Biochem. 1973; 33: 123
  • Franco L., Johns E. W., Navlet J. M. Histones from Baker's yeast, isolation and fractionatio. Eur. J. Biochem. 1975; 45: 83
  • Lohr D., van Holde K. E. Yeast chromatin subunit structur. Science 1975; 188: 165
  • Hollenberg C. P., Borst P., vanBruggen E. F. J. Mitochondrial DNA. V. A 25-μ closed circular duplex DNA molecule in wild-type yeast mitochondria. Structure and genetic complexit. Biochim. Biophys. Acta 1970; 209: 1
  • Bernardi G., Carnevali F., Nicolaieff A., Piperno G., Tecce G. Separation and characterization of a satellite DNA from a yeast cytoplasmic “petite” mutan. J. Mol. Biol. 1968; 37: 493
  • Bak A. L., Christiansen C., Stenderup A. Unusual physical properties of mitochondrial DNA in yeas. Nature 1969; 224: 270
  • Marmur J., Dory P. Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperatur. J. Mol Biol. 1962; 5: 109
  • Bernardi G., Faures M., Piperno G., Slonimski P. Mitochondrial DNA's from respiratory-sufficient and cytoplasmic respiratory-deficient mutant yeas. J. Mol Biol. 1970; 48: 23
  • Bernardi G., Timasheff S. N. Optical rotatory dispersion and circular dichroism properties of yeast mitochondrial DNA'. J. Mol. Biol. 1970; 48: 43
  • Bak A. L., Christiansen C., Stenderup A. Bacterial genome sizes determined by DNA renaturation studie. J. Gen. Microbiol. 1970; 64: 377
  • Bernardi G., Piperno G., Fonty G. The mitochondrial genome of wild-type yeast cells. I. Preparation and heterogeneity of mitochondrial DN. J. Mol. Biol. 1972; 65: 173
  • Piperno G., Fonty G., Bemardi G. The mitochondrial genome of wild-type yeast cells. II. Investigations on the compositional heterogeneity of mitochondrial DN. J. Mol. Biol. 1972; 65: 191
  • Carnevali F., Leoni L. Intramolecular heterogeneity of yeast mitochondrial DN. Biochem. Biophys. Res. Commun. 1972; 47: 1322
  • Ehrlich S. D., Thiery J. P., Bernardi G. The mitochondrial genome of wild-type yeast cells. III. The pyrimidine tracts of mitochondrial DN. J. Mol. Biol. 1972; 65: 207
  • Christiansen C., Bak A. L., Stenderup A., Christiansen G. Repetitive DNA in yeas. Nat. New Biol. 1971; 231: 176
  • Christiansen C., Christiansen G., Bak A. L. Heterogeneity of mitochondrial DNA from Saccharomyces carlsbergensis: renaturation and sedimentation studie. J. Mol. Biol. 1974; 84: 65
  • Thomas C. A., Jr. The arrangement of information in DNA molecule. J. Gen. Physiol. 1966; 49(6, Part 2)143
  • Pruned A., Bernardi G. The mitochondrial genome of wild-type yeast cells. IV. Genes and spacer. J. Mol. Biol. 1974; 86: 825
  • Mounolou J.-C., Jakob H., Slonimski P. Mitochondrial DNA from yeast “petite” mutants: specific changes of buoyant density corresponding to different cytoplasmic mutation. Biochem. Biophys. Res. Commun. 1966; 24: 218
  • Carnevalli F., Morpurgo C., Tecce G. Cytoplasmic DNA from petite colonics of Saccharomyces cerevisiae: a hypothesis on the nature of the mutatio. Science 1969; 163: 1331
  • Mehrota B. D., Mahler H. R. Characterization of some unusual DNA's from the mitochondria from certain “petite” strains o. Saccharomyces cerevisiae, Arch. Biochem. Biophys. 1968; 128: 685
  • Grossman L. I., Cryer D. R., Goldring E. S., Marmur J. The petite mutation in yeast. III. Nearest neighbor analysis of mitochondrial DNA from normal and mutant cell. J. Mol. Biol. 1971; 62: 565
  • Cohen M., Casey J., Rabinowitz M., Getz G. S. Hybridization of mitochondrial transfer RNA and mitochondrial DNA in peptite mutants of yeas. J. Mol. Biol. 1972; 63: 44
  • Fauman M., Rabinowitz M., Getz G. S. Base composition and sedimentation properties of mitochondrial RNA of Saccharomyces cerevisiae, Biochi. Biophys. Acta 1969; 182: 355
  • Gordon P., Rabinowitz M. Evidence for deletion and changed sequence in the mitochondrial deoxyribonucleic acid of a spontaneously generated petite mutant o. Saccharomyces cerevisiae, Biochemistry 1973; 12: 116
  • Van Kreijl C. F., Borst P., Flavell R. A., Hollenberg C. P. Pyrimidine tract analysis of mit-DNA from a “low-density” petite mutant of yeas. Biochim. Biophys. Acta 1972; 277: 61
  • Sanders J. P. M., Flavell R. A., Borst P., Mol J. N. M. Nature of the base sequence conserved in the mitochondrial DNA of a low density petite mutant of yeas. Biochim. Biophys. Acta 1973; 312: 41
  • Hollenberg C. P., Borst P., Flavell R. A., van Kreijl C. F., van Bruggen E. F. J., Amberg A. C. The unusual properties of mitochondrial DNA from a “low-density” petite mutant of yeas. Biochim. Biophys. Acta 1972; 227: 44
  • Lazowska J., Michel F., Faye G., Fukuhara H., Slonimski P. P. Physical and genetic organization of Petite and Grande yeast mitochondrial DNA. II. DNA-DNA hybridization studies and buoyant density determination. J. Mol. Biol. 1974; 85: 393
  • Locker J., Rabinowitz M., Getz G. S. Electron microscope and renaturation kinetic analysis of mitochondrial DNA of cytoplasmic petite mutants of Saccharomyces cerevisia. J. Mol. Biol. 1974; 88: 489
  • Fukuhara H., Gaye G., Michel F., Lazowska J., Deutsch J., Boiotin-Fukuhara M., Slonimski P. P. Physical and genetic organization of Petite and Grande yeast mitochondrial DNA. I. Studies by RNA-DNA hybridizatio. Mol. Gen. Genet. 1974; 130: 215
  • Faye G., Fukuhara H., Grandchamp C., Lazowska J., Michel F., Casey J., Getz G. S., Locker J., Rabinowitz M., Boiotin-Fukuhara M., Coen D., Deutsch J., Dujon B., Netter P., Slonimski P. P. Mitochondrial nucleic acids in the petite colonie mutants: deletions and repetitions of gene. Biochimie 1973; 55: 779
  • Gordon P., Casey J., Rabinowitz M. Characterization of mitochondrial deoxyribonucleic acid from a series of petite yeast strains of deoxyribonucleic acid-deoxyribonuclcic acid hybridizatio. Biochemistry 1974; 13: 1067
  • Michel F., Lazowska J., Faye G., Fukuhara H., Slonimski P. P. Physical and genetic organization of petite and grande yeast mitchondrial DNA. III. High resolution melting and reassociation studie. J. Mol. Biol. 1974; 85: 411
  • Locker J., Rabinowitz M., Getz G. S. Tandem inverted repeats in mitochondrial DNA of petite mutants of Saccharomyces cerevisiae, Proc. Nat. Acad. Sci. U.S.A. 1974; 71: 1366
  • Michels C. A., Blamire J., Goldfinger B., Marmur J. A genetic and biochemical analysis of petite mutations in yeas. J. Mol. Biol. 1974; 90: 431
  • Sinclair J. H., Stevens B. J., Sanghavi P., Rabinowitz M. Mitochondrial-satellite and circular DNA filaments in yeas. Science 1967; 156: 1234
  • Dark-Walker G. D., Miklos G. L. G. Localization and quantification of circular DNA in yeas. Eur. J. Biochem. 1974; 41: 359
  • Zeman L., Lusena C. V. Closed circular DNA associated with yeast mitochondri. FEBS Lett. 1974; 38: 171
  • Griffiths D. E., Lancashire W. E., Zanders E. D. Evidence for an extra-chromosomal element involved in mitochondrial function: a mitochondrial cpisom. FEBS Lett. 1975; 53: 126
  • Petes T. D., Williamson D. H. Replicating circular DNA molecules in yeas. Cell 1975; 4: 249
  • Dutta S. K. Repeated DNA sequences in fung. Nucleic Acids Res. 1974; 1: 1411
  • Rusch H. P. Some biochemical events in the life cycle of Physarum polycephalum. Advances in Cell Biology, D. Presscott, L. Goldstein, E. McConkey. Appleton-Century-Crofts-Meredith, New York 1970; Vol. 1
  • Adler P. N., Holt C. E. Mating type and the differentiated state in Physarum polycephalum, De. Biol. 1975; 43: 240
  • Cooke D. J., Dee J. Plasmodium formation without change in nuclear DNA content in Physarum polycephalum, Gene. Res. Camb. 1974; 23: 307
  • Holt C. E., Personal communication.
  • Adler P. N., Davidow L. S., Holt C. E. Life cycle variants of Physarum polycephalum that lack the amoeba stag. Science 1975; 190: 65
  • Mohberg J., Babcock K. L., Haugli F. B., Rusch H. P. Nuclear DNA content and chromosome numbers in the Myxomycet. Physarum polycephalum, Dev. Biol. 1973; 34: 228
  • Mohberg J., Rusch H. P. Isolation and content of Physarum polycephalum, Ex. Cell Res. 1971; 66: 305
  • Fouquet H., Bierweiler B., Sauer H. W. Reassociation kinetics of nuclear DNA from Physarum polycephalu. Eur. J. Biochem. 1974; 44: 407
  • Holt C. E., Gurney E. G. Minor components of the DNA of Physarum polycephalum, cellular location and metabolis. J. Cell Biol. 1969; 40: 484
  • Evans T. E., Suskind D. Characterization of the mitochondrial DNA of the slime mold Physarum polycephalum, Biochi. Biophys. Acta 1971; 228: 350
  • Braun R., Evans T. E. Replication of nuclear satellite and mitochondrial DNA in the mitotic cycle of Physarum, Biochi. Biophys. Acta 1969; 182: 511
  • Braun R., Mittermayer C., Rusch H. P. Sequential temporal replication of DNA in Physarum polycephalum, Pro. Natl. Acad. Sci. U.S.A. 1965; 53: 924
  • Zellweger A., Ryser U., Braun R. Ribosomal genes of Physarum: their isolation and replication in the mitotic cycl. J. Mol. Biol. 1972; 64: 681
  • Guttes E. W., Hanawalt P. C., Guttes S. Mitochondrial DNA synthesis and the mitotic cycle in Physarum polycephalum, Biochi. Biophys. Acta 1967; 142: 181
  • Sachsenmaier W. Zur DNS- und RNS-Synthese im Teilungscyclus synchroner Plasmodien von Physarum polycephalu. Biochem. Z. 1964; 340: 541
  • Evans T. E. Synthesis of a cytoplasmic DNA during the G2 interphase of Physarum polycephalum, Bioche. Biophys. Res. Commun. 1966; 22: 678
  • Guttes E., Guttes S. Thymidine incorporation by mitochondria in Physarum polycephalu. Science 1964; 145: 1057
  • Brewer E. N., DeVries A., Rusch H. P. DNA synthesis by isolated mitochondria of Physarum polycephalum, Biochi. Biophys. Acta 1967; 145: 686
  • Sonenshein G. E., Holt C. E. Molecular weight of mitochondrial DNA in Physarum polycephalum, Bioche. Biophys. Res. Commun. 1968; 33: 361
  • Flavell R. A., Jones I. G. Mitochondrial deoxyribonculeic acid from Tetrahymena pyriformis and its kinetic complexit. Biochem. J. 1970; 116: 811
  • Flavell R. A., Jones I. G. Paramecium mitochondrial DNA. Renaturation and hybridisation studie. Biochim. Biophys. Acta 1970; 232: 255
  • Guttes S., Guttes E., Hadek R. Occurrence and morphology of a fibrous body in the mitochondria of the slime mol. Physarum polycephalum, Experientia 1966; 22: 452
  • Nicholls T. J. The effects of starvation and light on intra-mitochondrial granules in Physarum polycephalu. J. Cell Sci. 1972; 10: 1
  • Stokem W. Uber den DNA-und RNS-gehalt der mitochondrien von Physarum polycephalu. Histochemie 1968; 15: 160
  • Guttes E., Guttes S., Vimla Devi R. Division stages of the mitochondria in normal and actinomycin-treated Plasmodia of Physarum polycephalu. Experientia 1969; 25: 66
  • Kuroiwa T. Studies on mitochondrial structure and function in Physarum polycephalum. I. Fine structure, cytochemistry, and 3H-uridine autoradiography of central body in mitochondri. Exp. Cell Res. 1973; 78: 351
  • Kuroiwa T. Studies on mitochondrial structure and function in Physarum polycephalum. III. Electron microscopy of a large amount of DNA released from a central body in mitochondria by trypsin digestio. J. Cell Biol. 1974; 63: 299
  • Kuroiwa T. Studies on mitochondrial structure and function in Physarum polycephalum. II. Behavior of RNA synthesized in central body of mitochondria as revealed by electron microscopic autoradiograph. J. Electron Microsc 1973; 22: 45
  • Bohnert H.-J., Schiller B., Bohme R., Sauer H. W. Circular DNA and rolling circles in nucleolar rDNA from mitotic nuclei of Physarum polycephalum, Eu. J. Biochem. 1975; 57: 361
  • Hourcade D., Dressier D., Wolfson J. The amplification of ribosomal RNA genes involves a rolling circle intermediate, Proc. Nat. Acad. Sci. U.S.A. 1973; 70: 2926
  • Rochaix J. D., Bird A., Bakken A. Ribosomal RNA gene amplification by rolling circle. J. Mol. Biol. 1974; 87: 473
  • Nygaard O. F., Guttes S., Rusch H. P. Nucleic acid metabolism in a slime mold with synchronous mitosi. Biochim. Biophys. Acta 1960; 38: 298
  • Sachsenmaier W., Rusch H. P. The effect of 5-fluoro-2′-deoxyuridine on synchronous mitosis in Physarum polycephalum, Ex. Cell Res. 1964; 36: 124
  • Braun R., Wili H. Time sequence of DNA replication in Physarum, Biochi. Biophys. Acta 1969; 174: 246
  • Kuroiwa T. Fine structure of interphase nuclei. VI. Initiation and replication sites of DNA synthesis in the nuclei of Physarum polycephalum as revealed by electron microscopic autoradiograph. Chromosoma 1973; 44: 291
  • Brewer E. N. DNA replication in Physarum polycephalu. J. Mol. Biol. 1972; 68: 401
  • Taylor J. H. Patterns and mechanisms of genetic recombinatio. Molecular Genetics, Part II, J. H. Taylor. Academic Press, New York 1967; 95
  • Brewer E. N., Evans T. E., Evans H. H. Studies on the mechanism of DNA replication in Physarum polycephalu. J. Mol. Biol. 1974; 90: 335
  • Brewer E. N. DNA replication by a possible continuous-discontinuous mechanism in homogenates of Physarum polycephalum containing Dextra. Biochim. Biophys. Acta 1975; 402: 363
  • Waqar M. A., Huberman J. A. Covalent linkage between RNA and nascent DNA in the slime mold, Physarum polycephalum, Biochi. Biophys. Acta 1975; 383: 410
  • Sugino A., Okazaki R. RNA-linked DNA fragments in vitro, Proc. Nat. Acad. Sci. U.S.A. 1973; 70: 88
  • Jockusch N. M., Walker I. O. The preparation and preliminary characterisation of chromatin from the slime moul. Physarum polycephalum, Eur. J. Biochem. 1974; 48: 417
  • Mohberg J., Rusch H. P. Isolation of the nuclear histones from the Myxomycete, Physarum polycephalum, Arc. Biochem. Biophys. 1969; 134: 577
  • Bonner J. T. The Cellular Slime Molds. Princeton University Press, Princeton 1967
  • Sinha U., Ashworth J. M. Evidence for the existence of elements of a para-sexual cycle in the cellular slime mould, Dictyostelium discoideum, Proc. R. So. London Ser. B 1969; 173: 531
  • Loomis W. F., Jr. Temperature-sensitive mutants of Dictyostelium discoideu. J. Bacteriol. 1969; 99: 65
  • Brody T., Williams K. L. Cytological analysis of the parasexual cycle in Dictyostelium discoideu. J. Gen. Microbiol. 1974; 82: 371
  • Sackin M. J., Ashworth J. M. An analysis of the distribution of volumes amongst spores of the cellular slime mould Dictyostelium discoideu. J. Gen. Microbiol. 1969; 59: 275
  • Wilson C. M., Ross I. K. Further cytological studies in the Acrasiale. Am. J. Bot. 1957; 44: 345
  • Sussman M. “Fruity” and other mutants of the cellular slime mould, Dictyostelium discoideum: a study of developmental aberration. J. Gen. Microbiol. 1955; 13: 295
  • Sussman R., Rayner E. P. Physical characterization of deoxyribonucleic acids in Dictyostelium discoideum, Arc. Biochem. Biophys. 1971; 144: 127
  • Firtel R. A., Bonner J. Characterization of the genome of the cellular slime mold Dictyostelium discoideu. J. Mol Biol. 1972; 66: 339
  • Erickson R. L., Szybalski W. The Cs2SO4 equilibrium density gradient and its application for the study of T-even phage DNA: Glucosylation and replicatio. Virology 1964; 22: 11
  • Szybalski W., Szybalski E. H. Equilibrium density gradient centrifugatio. Procedures in Nucleic Acid Research, G. L. Cantoni, D. R. Davies. Harper and Row, New York 1971; Vol. 2
  • Bak A. L., Black F. T., Christiansen C., Freundt E. A. Genome size of mycoplasmal DN. Nature 1964; 224: 1209
  • Seidler R. J., Mandel M. Quantitative aspects of deoxyribonucleic acid renaturation: base composition, state of chromosome replication, and polynucleotide homologie. J. Bacteriol. 1971; 106: 698
  • Borst P. Mitochondrial nucleic acid. Annu. Rev. Biochem. 1972; 41: 333
  • Firtel R. A., Kindle K. Structural organization of the genome of the cellular slime mold Dictyostelium discoideum: interspersion of repetitive and single-copy DNA sequence. Cell 1975; 5: 401
  • Graham E. E., Neufeld B. R., Davidson E. H., Britten R. J. Interspersion of repetitive and non-repetitive DNA sequences in the sea-urchin genom. Cell 1974; 1: 127
  • Davidson E. H., Hough B. R., Amenson C. S., Britten R. J. General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopu. J. Mol. Biol. 1973; 77: 1
  • Ammerman D. Riesenchromosomen in der makronucleus-anlage des Ciliate. Stylonychia spec, Naturwissenschaften 1964; 51: 249
  • Ammerman D. Cytologische und genetische Untersuchungen an dem ciliaten, Stylonychia mytilu. Arch. Protistenk. 1965; 108: 109
  • Ammerman D. Synthese und Abbau der Nukleinsäuren während der Entwicklung des Makronucleus von Stylonychia mytilus (Protozoa, Ciliata. Chromosoma 1968; 25: 107
  • Ammerman D. Release of DNA breakdown products into the culture medium of Stylonychia mytilus exconjugants (protozoa, ciliata) during their destruction of the polytene chromosome. J. Cell Biol. 1969; 40: 576
  • Ammerman D. Morphology and development of the macronuclei of the ciliates Stylonychia mytilus and Euplotes aediculatu. Chromosoma 1971; 33: 209
  • Murti K. G. Electron-microscopic observations on the macronuclear development of Stylonychia mytilus and Tetrahymena pyriformis (ciliophora-protozoa. J. Cell Sci. 1973; 13: 479
  • Murti K. G., Prescott D. M., Peni J. J. DNA of ciliated polymerase and denaturation at the ends of the low molecular weight DNA in Stylonychi. J. Mol Biol. 1972; 68: 413
  • Prescott D. M., Murti K. G., Bostock C. J. Genetic apparatus of Stylonychia spe. Nature 1973; 242: 576
  • Prescott D. M., Bostock C. J., Murti K. G., Lauth M. R., Gamow E. DNA of ciliated protozoa. I. Electron microscopic and sedimentation analyses of macronuclear and micronuclear DNA of Stylonychia mytilu. Chromosoma 1971; 34: 355
  • Prescott D. M., Murti K. G. Chromosome structure in ciliated protozoans, Cold Spring Harbor Sym. Quant. Biol. 1973; 38: 609
  • Bostock C. J., Prescott D. M. Evidence of gene diminution during the formation of the macronucleus in the protozoan, Stylonychia, Proc. Nat. Acad. Sci. U.S.A. 1972; 69: 139
  • Lauth M. R., Heumann J., Spear B. B., Prescott D. M. DNA of ciliated protozoa. V. DNA sequence diminution during macronuclear development of Oxytricha, Cell, submitted.
  • Wesley R. D. Inverted repetitious sequences in the macronuclear DNA of hypotrichous ciliate. Proc. Natl. Acad. Sci. U.S.A. 1975; 72: 678
  • Allen S., Gibson I. Genome amplification and gene expression in the ciliate macronucleu. Biochem. Genet. 1972; 6: 293
  • Woodard J., Gorovsky M., Kaneshiro E. Macronuclear subnuclei of Tetrahymen. J. Cell Biol. 1968; 39: 182a
  • Orias E., Flacks M. Macronuclear genetics of Tetrahymena. I. Random distribution of macronuclear gene copies in T. pyriformis, Syngen . Genetics 1975; 79: 187
  • Suyama Y., Miura K. Size and structural variations of mitochondrial DNA, Proc. Nat. Acad. Sci. U.S.A. 1968; 60: 235
  • Borst P. Mitochondrial nucleic acid. Annu. Rev. Biochem. 1972; 41: 333
  • Arnberg A. C., Van Bruggen E. F. J., Borst P., Clegg R. A., Hutgens R. B. H., Weijers P. J., Goldbach R. W. Mitochondrial DNA of Tetrahymena pyriformis strain ST contains a long terminal duplication-inversio. Biochim. Biophys. Acta 1975; 383: 359
  • Iwai K., Ham-an-a K., Yabuki H. Histone fractions of protozoa: their correlation of mammalian histone. J. Biochem. (Tokyo) 1970; 68: 597
  • Hamana K., Iwai K. Fractionation and characterization of Tetrahymena histone in comparison with mammalian histone. J. Biochem. (Tokyo) 1971; 69: 1097
  • Elgin S. C. R., Weintraub H. Chromosomal proteins and chromatin structur. Annu. Rev. Biochem. 1975; 44: 725
  • Maizocco A., Colli W. Isolation of nuclei and characterization of nuclear DNA of Acanthamoeha castellanii, Biochi. Biophys. Acta 1974; 374: 292
  • Maizocco A., Colli W. Characterization of the genome of the small free-living amoeba Acanthamoeha castellanii, Biochi. Biophys. Acta 1975; 395: 525
  • Bohneit H. J., Herrmann R. G. The genomic complexity of Acanthamoeha castellanii mitochondrial DN. Eur. J. Biochem. 1974; 50: 83
  • Tautvydas K. J. Mass isolated amoeba. I. Isolation procedure and determination of macromolecular composition and RNA polymerase activit. Exp. Cell Res. 1971; 68: 299
  • Chia D., Schumaker V. N. A rotor speed dependent crossover in sedimentation velocities of DNA's of different site. Biochem. Biophys. Res. Commun. 1974; 56: 241
  • Ammerman D., Steinbrück G., von Berger L., Hennig W. The development of the macronucleus in the ciliated protozoa. Stylonichia mytilis, Chromosoma 1974; 45: 401
  • Gillis M., DeLey J. Determination of the molecular complexity of double-stranded phage genome DNA from initial renaturation rates. The effect of DNA base compositio. J. Mol. Biol. 1975; 98: 447

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