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Original Article

Molecular Cloning of Canine and Feline Flt3 Ligand Reveals High Degree of Similarity to the Human and Mouse Homologue But Uniquely Long Cytoplasmic Domain

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Pages 163-166 | Received 13 Sep 1999, Published online: 11 Jul 2009

References

  • Hannum C., Culpepper J., Campbell D., McClanahan T., Zurawski S., Bazan J. F., Kastelein R., Hudak S., Wagner J., Mattson J., Luh J., Duda G., Martina N., Peterson D., Menon s., Shanafelt A., Muench M., Kelner G, Namikawa R., Rennick D., Roncarolo M.-G., Zlot-nik A., Rosnet O., Dubreuil P., BirnbaumI D., Lee F. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. Nature 1994; 368: 643–648
  • Lyman S. D., Jacobsen S. E. c-kit ligand and Flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities. Blood 1998; 91: 1101–1134
  • Lyman S. D., James L., Bos T. V., Vries P., Brasel K, Glin-iak B., Hollingsworth L. T., Picha K. S., McKenna H. J., Splett R. R., Fletcher F. A., Maraskovsky E., Farrah T., Foxworthe D., Williams D. E., Beckmann M. P. Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells. Cell 1993; 75: 1157–1167
  • Lyman S. D., James L., Johnson L., Brasel K., Vries P., Escobar S. S., Downey H., Splett R. R., Beckmann M. P., McKenna H. J. Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells. Blood 1994; 83: 2795–2801
  • Lyman S. D., James L., Escobar S., Downey H., Vries P., Brasel K., Stocking K., Beckmann M. G., Copeland N. G., Cleveland L. S., Jenkins N. A., Belmont J. W., Davison B. L. (a). Identification of soluble and membrane-bound isoforms of the murine flt3 ligand generated by alternative splicing of mRNAs. Oncogene 1995; 10: 149–157
  • Lyman S. D., Stocking K., Davison B., Fletcher F., Johnson L., Escobar S. (b). Structural analysis of human and murine flt3 ligand genomic loci. Oncogene 1995; 11: 1165–1172
  • McClanahan T., Culpepper J., Campbell D., Wagner J., Franz-Bacon, Mattson K., J., Tsai S., Luh J., Guimaraes M. J., Mattei M.-G., Rosnet, Birnbaum O. I. D., Han-num C. H. Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand. Blood 1996; 88: 3371–3382

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