5
Views
17
CrossRef citations to date
0
Altmetric
Original Article

Multiple potential regulatory elements in the 5′ flanking region of the β-adrenergic receptor

&
Pages 61-63 | Received 01 Mar 1991, Published online: 11 Jul 2009

References

  • Collins S., Bouvier M., Bolanowski M. S., Caron M. G., Lefkowitz R. J. Cyclic AMP stimulates transcription of the β2-adrenergic receptor gene in response to short term agonist exposure. Proc. Natl. Acad. Sci. U.S.A 1989; 86: 4853–4857
  • Collins S., Altschmied J., Herbsman O., Caron M. G., Mellon P. L., Lefkowitz R. J. A cAMP response element in the β2-AR gene confers transcriptional autoregulation of cAMP. J. Biol. Chem 1990; 265: 19330–19335
  • Emorine L. J., Marullo S., Briend-Sutren M., Patey G., Tate K., Delavier-Klutchko C., Strosberg A. D. Molecular characterization of the human β3-adrenergic receptor. Science 1989; 245: 1118–1121
  • Frielle T., Collins S., Daniel K. W., Caron M. G., Lefkowitz R. J., Kobilka B. K. Cloning of the cDNA for the β1-adrenergic receptor. Proc. Natl. Acad. Sci. U.S.A 1987; 84: 7920–7924
  • Kobilka B. K., Frielle T., Dohlman H. G., Bolanowski M. A., Dixon R. A.F., Keller P., Caron M. G., Lefkowitz R. J. Delineation of the intronless nature of the genes for the human and hamster β2-adrenergic receptor and their putative promoter regions. J. Biol. Chem 1987; 262: 7321–7327
  • Liggett S. B., Bouvier M., Hausdorff W. P., O'Dowd B., Caron M. G., Lefkowitz R. J. Altered patterns of agoniststimulated cAMP accumulation in cells expressing mutant β2-adrenergic receptors lacking phosphorylation sites. Mol. Pharmacol 1989; 36: 641–646
  • Liggett S. B. Desensitization of the β-adrenergic receptor: Distinct molecular determinants of phosphorylation by specific kinases. Pharmacol. Research 1991, (in press)
  • O'Dowd B. F., Collins S., Bouvier M., Caron M. G., Lefkowitz R. J. Structural, functional and genetic aspects of receptors coupled to G proteins. Molecular Biology of Receptors Which Couple to G-proteins, M. Brann. Birkhauser Boston, Inc., Cambridge, (in press)
  • Roesler W. J., Vandenbark G. R., Hanson R. W. Cyclic AMP and the induction of eukaryotic gene transcription. J. Biol. Chem 1988; 263: 9063–9066
  • Raymond J. R., Hnatowich M., Lefkowitz R. J., Caron M. G. Adrenergic receptors: models for regulation of signal transduction processes. Hypertension 1990; 15: 119–131
  • Smith T. H., Waterman M. S. Identification of common molecular subsequences. J. Mol. Biol 1981; 147: 195–7
  • Zaagsma J., Nahorski S. Is the adipocyte β-adrenoceptor a prototype for the recently cloned atypical β3-adrenoceptor?. Trends in Pharmacol. Sci 1990; 11: 3–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.