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Original Article

Cloning of cDNAs Encoding Human Synapsins Ha and IIb

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Pages 49-54 | Received 30 Mar 1998, Published online: 11 Jul 2009

References

  • Browning M. D., Dudek E. M., Rapier J. L., Leonard S., Freedman R. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biol. Psych. 1993; 34: 529–35
  • Chin L. S., Li L., Ferreira A., Kosik K. S., Greengard P. Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice. Proc. Natl. Acad. Sci. USA 1995; 92: 9230–4
  • Ferreira A., Han H.-Q., Greengard P., Kosik K. S. Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture. Proc. Natl. Acad. Sci. USA 1995; 92: 9225–9
  • Ferreira A., Kosik K. S., Greengard P., Han H.-Q. Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons. Science 1994; 264: 977–9
  • Ferreira A., Li L., Chin L.-S., Kosik K. S., Greengard P. Distinct roles of synapsin I and synapsin II during neuronal development. Molecular Medicine 1998; 4: 22–8
  • Frohman M. A., Dush M. K., Martin G. R. Rapid production of fulllength cDNAs from rare transcripts: amplification using a single genespecific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 1988; 85: 8998–9002
  • Gill M., Vallada H., Collier D., Sham P., Holmans P., Murray R., McGuffin P., Nanko S., Owen M., Antonarakis S., Housman D., Kazazian H., Nestadt G., Pulver A. E., Straub R. E., MacLean C. J., Walsh D., Kendler K. S., DeLisi L., Polymeropoulos M., Coon H., Byerley W., Lofthouse R., Gershon E., Golden L., Crow T., Byerley W., Coon H., Freedman R., Laurent C., Bodeau-Pean S., D'Amato T., Jay M., Campion D., Mallet J., Wildenauer D. B., Lere B., Albus M., Ackenheil M., Ebstein R. P., Hallmayer J., Maier W., Curling H., Curtis D., Gusharon K., Brynjolfsson J., Sigmundson T., Petursson H., Blackwood D., Muir W., St. Clair D., He L., Maguire S., Moises H. W., Hwu H.-G., Yang L., Wiese C., Tao L., Liu X., Kristbjarnason H., Levinson D. F., Mowry B. J., Donis-Keller H., Hayward N. K., Crowe R. R., Silverman J. M., Nancarrow D. J., Read C. M. A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). Am. J. Med. Genet. 1996; 67: 40–5
  • Grebb J. A., Browning M. D., Valverius P., Borg S., Sedvall G., Greengard P. An analysis of postmortem brain samples from 32 alcoholic and nonalcoholic individuals for protein III, a neuronal phosphoprotein. Alcohol. Ctin. Exp. Res. 1989; 13: 673–9
  • Grebb J. A., Greengard P. An analysis of synapsin II, a neuronal phosphoprotein, in postmortem brain tissue from alcoholic and neuropsychiatrically ill adults and medically ill children and young adults. Arch. Gen. Psych. 1990; 47: 1149–56
  • Greengard P., Valtorta F., Czernik A. J., Benfenati F. Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 1993; 259: 780–5
  • Hackett J. T., Cochran S. L., Greenfield L. J., Jr., Brosius D. C., Ueda T. Synapsin I injected presynaptically into goldfish mauthner axons reduces quantal synaptic transmission. J. Neurophys. 1990; 63: 701–6
  • Hamos J. E., DeGennaro L. J., Drachman D. A. Synaptic loss in Alzheimer's disease and other dementias. Neurology 1989; 39: 355–61
  • Han H.-Q., Nichols R. A., Rubin M. R., Bahler M., Greengard P. Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb. Nature 1991; 349: 697–700
  • Hosaka M., Südhof T. C. Synapsin III, a novel synapsin with an unusual regulation by Ca2+. J. Biol. Chem. 1998; 273: 13371–4
  • Kao H.-T., Porton B., Czernik A. J., Feng J., Yiu G., Häring M., Benfenati F., Greengard P. A Third Member of the Synapsin Gene Family. Proc. Natl. Acad. Sci. USA 1998; 95: 4667–72
  • Li L., Chin L.-S., Shupliakov O., Brodin L., Sihra T. S., Hvalby Ø., Jensen V., Zheng D., McNamara J. O., Greengard P., Andersen P. Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice. Proc. Natl. Acad. Sci. USA 1995; 92: 9235–9
  • Llinás R., Gruner J. A., Sugimori M., McGuinness T. L., Greengard P. Regulation by synapsin I and Ca(2+)-calmodulin-dependent protein kinase II of the transmitter release in squid giant synapse. J. Physiol. 1991; 436: 257–82
  • Llinás R., McGuinness T. L., Leonard C. S., Sugimori M., Greengard P. Intraterrninal injection of synapsin I or calcium/calmodulindependent protein kinase II alters neurotransmitter release at the squid giant synapse. Proc. Natl Acad. Sci. USA 1985; 82: 3035–9
  • Lu B., Greengard P., Poo M.-m. Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses. Neuron 1992; 8: 521–9
  • Perdahl E., Adolfsson R., Alafuzoff I., Albert K. A., Nestler E. J., Greengard P., Winblad B. (a). Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia. J. Neural Transmiss. 1984; 60: 133–41
  • Perdahl E., Wu W. C., Browning M. D., Winblad B., Greengard P. (b). Protein III, a neuron-specific phosphoprotein: variant forms found in human brain. Neurobehav. Toxicol. Teratol. 1984; 6: 425–31
  • Pieribone V. A., Shupliakov O., Brodin L., Hilfiker-Rothenfluh S., Czernik A. J., Greengard P. Distinct pools of synaptic vesicles in neurotransmitter release. Nature 1995; 375: 493–7
  • Rosahl T. W., Spillane D., Missler M., Herz J., Selig D. K., Wolff J. R., Hammer R. E., Malenka R. C., Südhof T. C. Essential functions of synapsins I and H in synaptic vesicle regulation. Nature 1995; 375: 488–93
  • Schaeffer E., Alder J., Greengard P., Poo M.-m. Synapsin Ha accelerates functional development of neuromuscular synapses. Proc. Natl. Acad. Sci. USA 1994; 91: 3882–6
  • Südhof T. C. The structure of the human synapsin I gene and protein. J. Biol. Chem. 1990; 265: 7849–52
  • Valtorta F., Iezzi N., Benfenati F., Lu B., Poo M.-M., Greengard P. Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis. Eur. J. Neurosci. 1995; 7: 261–70
  • Walaas S. I., Perdahl-Wallace E., Winblad B., Greengard P. Protein phosphorylation systems in postmortem human brain. J. Mol. Neurosci. 1989; 1: 105–16
  • Xie Y. Cloning and sequencing analysis of a human synapsin lib-encoding brain cDNA. Gene 1996; 173: 289–90

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