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Original Article

Broad Alterations of Self-Reactive Antibody-Repertoires of Plasma IgM and IgG in B-Cell Chronic Lymphocytic Leukemia (B-CLL) and B-CLL Related Target-Restricted Autoimmunity

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Pages 163-176 | Published online: 01 Jul 2009

References

  • Kipps T. J., Carson D. A. Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases. Blood 1993; 81: 2475–2487
  • Caligaris-Cappio F. B-chronic lymphocytic leukemia: a malignancy of anti-self B cells. Blood 1996; 87: 2615–2620
  • Caligaris-Cappio F., Hamblin T. J. B-cell chronic lymphocytic leukemia: a bird of a different feather. Journal of Clinical Oncology 1999; 17: 399–408
  • Broker B. M., Klajman A., Youinou P., Jouquan J., Worman C. P., Murphy J., Mackenzie L., Quartey-Papafio R., Blaschek M., Collins P., Lal S., Lydyard P. M. Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies. Journal of Autoimmunity 1988; 1: 469–481
  • Borche L., Lim A., Binet J. L., Dighiero G. Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies. Blood 1990; 76: 562–569
  • Pritsch O., Magnac C., Dumas G., Egile C., Dighiero G. V gene usage by seven hybrids derived from CD5+ B-cell chronic lymphocytic leukemia and displaying autoantibody activity. Blood 1993; 82: 3103–3112
  • Maloum K., Davi F., Magnac C., Pritsch O., McIntyre E., Valensi F., Binet J. L., Merle-Beral H., Dighiero G. Analysis of VH gene expression in CD5+ and CD5-B-cell chronic lymphocytic leukemia. Blood 1995; 86: 3883–3890
  • Damle R. N., Wasil T., Fais F., Ghiotto F., Valetto A., Allen S. L., Buchbinder A., Budman D., Dittmar K., Kolitz J., Lichtman S. M., Schuhnan P., Vinciguerra V. P., Rai K. R., Ferrarini M., Chiorazzi N. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999; 94: 1840–1847
  • Sakai A., Marti G. E., Caporaso N., Pittaluga S., Touchman J. W., Fend F., Raffeld M. Analysis of expressed immunoglobulin heavy chain genes in familial B-CLL. Blood 2000; 95: 1413–1419
  • Haury M., Grandien A., Sundblad A., Coutinho A., Nobrega A. Global analysis of antibody repertoires. 1. An inununoblot method for the quantitative screening of a large number of reactivities. Scandinavian Journal of Immunology 1994; 39: 79–87
  • Stahl D., Lacroix-Desmazes S., Mouthon L., Kaveri S. V., Kazatchkine M. D. Analysis of human self-reactive antibody repertoires by quantitative immunoblotting (review). Journal of Immunological Methods 2000; 240: 1–14
  • Wissenschaftlicher Beirat der Bundesärztekammer und des Paul-Ehrlich-Institutes. Richtlinien zur Blutgruppenbestimmung und Hämotherapie. Deutscher ärzte-Verlag, KÖln 1996
  • Guide to the preparation, use and quality assurance of blood components. Council of Europe Press, Strasbourg 1995
  • Technical manual, V. Vengelen-Tyler. American Assocociation of Blood Banks (AABB), Bethesda, Maryland 1996
  • Lacroix-Desmazes S., Mouthon L., Pashov A., Barreau C., Kaveri S. V., Kazatchkine M. D. Analysis of antibody reactivities towards self antigens of IgM of patients with WaldenstrÖm's macroglobulinemia. International Immunology 1997; 9: 1175–1183
  • Mouthon L., Nobrega A., Nicolas N., Kaveri S. V., Barreau C., Coutinho A., Kazatchkine M. D. Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults. Proceedings of the National Academy of Science USA 1995; 92: 3839–3843
  • Mouthon L., Haury M., Lacroix-Desmazes S., Barreau C., Coutinho A., Kazatchkine M. D. Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues. Journal of Immunology 1995; 154: 5769–5778
  • Fesel C., Coutinho A. Dynamics of serum IgM autoreactive repertoires following immunization: strain specificity, inheritance and association with autoimmune disease susceptibility. European Journal of Immunology 1998; 28: 3616–3629
  • Stahl D., Lacroix-Desmazes S., Heudes D., Mouthon L., Kaveri S. V., Kazatchkine M. D. Altered control of self-reactive IgG by autologous IgM in patients with warm autoimmune hemolytic anemia. Blood 2000; 95: 328–335
  • Jobson J. D. Applied multivariate data analysis: Categorical and multivariate methods. Vol II. Springer Verlag, New York 1992
  • Chen Z. J., Wheeler C. J., Shi W., Wu A. J., Yarboro C. H., Gallagher M., Notkins A. L. Polyreactive antigen-binding B cells are the predominant cell type in the newborn B cell repertoire. European Journal of Immunology 1998; 28: 989–994
  • Casali P., Kasaian M. T., Haughton G. B-1 (CD5 B) cells. In Autoimmunity: Physiology and Disease, A. Coutinho, M. D. Kazatchkine. Wiley-Liss, New York 1994; 57–88
  • Lacroix-Desmazes S., Mouthon L., Coutinho A., Kazatchkine M. D. Analysis of the natural human IgG antibody repertoire: life-long stability of reactivities towards self antigens contrasts with age-dependent diversification of reactivities against bacterial antigens. European Journal of Immunology 1995; 25: 2598–2604
  • Mouthon L., Lacroix-Desmazes S., Nobrega A., Barreau C., Coutinho A., Kazatchkine M. D. The self-reactive antibody repertoire of normal human serum IgM is acquired in early childhood and remains stable throughout life. Scandinavian Journal of Immunology 1996; 44: 243–251
  • Lacroix-Desmazes S., Mouthon L., Kaveri S. V., Kazatchkine M. D., Weksler M. E. Stability of natural self-reactive antibody repertoires during aging. Journal of Clinical Immunology 1999; 19: 26–34
  • Francoeur A. M. Antibody fingerprinting: a novel method for identifying individual people and animals. Biotechnology 1988; 6: 822
  • Adib M., Ragimbeau J., Avrameas S., Ternynck T. IgG autoantibody activity in normal mouse serum is controlled by IgM. Journal of Immunology 1990; 145: 3807–3813
  • Hurez V., Kaveri S. V., Kazatchkine M. D. Expression and control of the natural autoreactive IgG repertoire in normal human serum. European Journal of Immunology 1993; 23: 783–789
  • Lacroix-Desmazes S., Resnick I., Stahl D., Mouthon L., Espanol T., Levy J., Kaveri S. V., Notarangelo L., Eibl M., Fischer A., Ochs H., Kazatchkine M. D. Defective self-reactive antibody repertoire of serum IgM in patients with hyper-IgM syndrome. Journal of Immunology 1999; 162: 5601–5608
  • Kneitz C., Goller M., Wilhelm M., Mehringer C., Wohlleben G., Schimpl A., Tony H. P. Inhibition of T cell/B cell interaction by B-CLL cells. Leukemia 1999; 13: 8–104
  • Varela F., Andersson A., Dietrich G., Sundblad A., Holmberg D., Kazatchkine M. D., Coutinho A. The population dynamics of antibodies in normal and autoimmune individuals. Proceedings of the National Academy of Science USA 1991; 88: 5917–5921
  • Stahl D., Venetz J. P., Lacroix-Desmazes S., Rondeau E., Bonnin E., Kazatchkine M. D., Ronco P., Kaveri S. V. Idiopathic membranous glomerulonephritis is associated with altered patterns of self-reactive IgM and IgG antibody repertoires. Submitted
  • Besa B. C. Recent advances in the treatment of chronic lymphocytic leukemia: defining the role of intravenous immunoglobulin. Seminars in Hematology 1992; 29: 14–23, Supplement 3
  • Sundblad A., Marcos M., Huetz F., Freitas A., Heusser C., Portnoi D., Coutinho A. Normal serum immunoglobulins influence the numbers of bone marrow pre-B and B cells. European Journal of Immunology 1991; 21: 1155–1161
  • Freitas A. A., Viale A. C., Sundblad A., Heusser C., Coutinho A. Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires. Proceedings of the National Academy of Science USA 1991; 88: 5640–55644
  • Dietrich G., Varela F. J., Hurez V., Bouanani M., Kazatchkine M. D. Selection of the expressed B cell repertoire by infusion of normal immunoglobulin G in a patient with autoimmune thyroiditis. European Journal of Immunology 1993; 23: 2930–2945
  • Lacroix-Desmazes S., Mouthon L., Spatter S. H., Kaveri S., Kazatchkine M. D. Immunoglobulins and the regulation of autoimmunity through the immune network. Clinical and Experimental Rheumatology 1996; 14: S9-S15, Supplement 15

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