Central nervous system involvement at presentation in childhood acute lymphoblastic leukemia: management experience and lessons

References

• Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006;354:166–178.
   PubMed Web of Science ®Google Scholar
• Vrooman LM, Silverman LB. Childhood acute lymphoblastic leukemia: update on prognostic factors. Curr Opin Pediatr 2009;21:1–8.
   PubMed Web of Science ®Google Scholar
• Sancho JM, Morgades M, Arranz R, et al Practice of central nervous system prophylaxis and treatment in acute leukemias in Spain. Prospective registry study. Med Clin (Barc) 2008;131:401–405.
   PubMed Web of Science ®Google Scholar
• Pui CH. Toward optimal central nervous system-directed treatment in childhood acute lymphoblastic leukemia. J Clin Oncol 2003;21:179–181.
   PubMed Web of Science ®Google Scholar
• Advani S, Pai S, Venzon D, et al Acute lymphoblastic leukaemia in India: An analysis of prognostic factors using a single treatment regimen. Ann Oncol 1999;10:167–176.
   PubMed Web of Science ®Google Scholar
• Luo XQ, Ke ZY, Huang LB, et al High-risk childhood acute lymphoblastic leukemia in China: factors influencing the treatment and outcome. Pediatr Blood Cancer 2009;52:191–195.
   PubMed Web of Science ®Google Scholar
• Chessells JM, Bailey CC, Richards S. MRC UKALL X. The UK protocol for childhood ALL: 1985–1990. Leukemia 1992;6:157–161.
   PubMed Web of Science ®Google Scholar
• Chessells JM, Bailey C, Richards SM. Intensification of treatment and survival in all children with lymphoblastic leukaemia: results of UK Medical Research Council trial UKALL X. Medical Research Council Working Party on Childhood Leukaemia. Lancet 1995;345:653.
   Web of Science ®Google Scholar
• Chessels JM, Harrison G, Richards SM, et al Failure of a new protocol to improve treatment results in paediatric lymphoblastic leukaemia: lessons from the UK Medical Research Council trials UKALL X and UKALL XI. Br J Haematol 2002;118:445–455.
   PubMed Web of Science ®Google Scholar
• Klabfleisch JD, Prentice RL. The statistical analysis of failure of time data. New York, NY: Wiley; 2002.
   Google Scholar
• Grey RJ. A class of K sample tests for comparing the cumulative incidence of competing risk. Ann Stat 1988;16:1141–1154.
   Web of Science ®Google Scholar
• Gaynon PS, Qu RP, Chappell RJ, et al Survival after relapse in childhood acute lymphoblastic leukemia: impact of site and time to first relapse – the Children's Cancer Group Experience. Cancer 1998;82:1387–1395.
   PubMed Web of Science ®Google Scholar
• Laningham FH, Kun LE, Reddick WE, Ogg RJ, Morris BE, Pui CH. Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae. Neuroradiology 2007;49:873–888.
   PubMed Web of Science ®Google Scholar
• Gao YJ, Lu FJ, Wang HS. Treating childhood acute lymphoblastic leukemia in a developing country 1998–2003: the experience of a single children's hospital in China. J Pediatr Hematol Oncol 2006;28:798–802.
   PubMed Web of Science ®Google Scholar
• Howard SC, Pedrosa M, Lins M, et al Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004;291:2471–2475.
   PubMed Web of Science ®Google Scholar
• Dabbous IA, Dbouk H, Sibai AM, Bahlawan L. Childhood acute lymphoblastic leukemia managed in tertiary care center in a developing country. Med Pediatr Oncol 2003;41:83–84.
   PubMedGoogle Scholar
• Kulkarni KP, Marwaha RK, Trehan A, Bansal D. Survival outcome in childhood ALL: experience from a tertiary care centre in North India. Pediatr Blood Cancer 2009;53:168–173.
   PubMed Web of Science ®Google Scholar
• Pui CH, Howard SC. Current management and challenges of malignant disease in the CNS in paediatric leukaemia. Lancet Oncol 2008;9:257–268.
   PubMed Web of Science ®Google Scholar
• Pui CH. Central nervous system disease in acute lymphoblastic leukemia: prophylaxis and treatment. Hematol Am Soc Hematol Educ Program 2006:142–146.
   PubMedGoogle Scholar
• Lee AC, Wong LG. Facial palsy, corticosteroids, and acute leukemia. Pediatr Neurol 2007;36:137.
   PubMed Web of Science ®Google Scholar
• Juhn YJ, Inoue S. Facial nerve palsy as an early manifestation of relapse in T-cell acute lymphoblastic leukemia. Ear Nose Throat J 1996;75:157–160.
   PubMedGoogle Scholar
• Antony R, Roebuck D, Hann IM. Unusual presentations of acute lymphoid malignancy in children. J R Soc Med 2004;97:125–127.
   PubMed Web of Science ®Google Scholar
• Shenoy A, Khajuria R, Malik N, Singhi S. Acute paraplegia as a presenting symptom of acute leukemia. Indian Pediatr 1988;25:569–571.
   PubMedGoogle Scholar
• Iqbal Y, Al-Sudairy R, Abdullah MF, Rafaie T, Al-Omari A. Spinal cord compression as an initial symptom in childhood acute lymphoblastic leukemia: rapid decompression with high dose dexamethasone and chemotherapy alone. Ann Saudi Med 2003;23:179–180.
   PubMed Web of Science ®Google Scholar
• Harada T, Namiki S, Kawabata I. Acute profound sensorineural hearing loss as the initial manifestation of acute leukemia – report of a case. Auris Nasus Larynx 2000;27:359–362.
   PubMedGoogle Scholar
• Veling MC, Windmill I, Bumpous JM. Sudden hearing loss as a presenting manifestation of leukemia. Otolaryngol Head Neck Surg 1999;120:954–956.
   PubMed Web of Science ®Google Scholar
• Gajjar A, Harrison PL, Sandlund JT, et al Traumatic lumbar puncture at diagnosis adversely affects outcome in childhood acute lymphoblastic leukemia. Blood 2000;96:3381–3384.
   PubMed Web of Science ®Google Scholar
• Howard SC, Gajjar AJ, Cheng C, et al Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia. JAMA 2002;288:2001–2007.
   PubMed Web of Science ®Google Scholar
• Magrath I, Shanta V, Advani S, et al Treatment of acute lymphoblastic leukaemia in countries with limited resources; lessons from use of a single protocol in India over a twenty year period. Eur J Cancer 2005;41:1570–1583.
   PubMed Web of Science ®Google Scholar
• Lazarus HM, Richards SM, Chopra R, et al Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL-XII/ECOG E2993. Blood 2006;108:465–472.
   PubMed Web of Science ®Google Scholar
• Bejel A, George B, Mathews V, et al Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol. Pediatr Blood Cancer 2008;51:621–625.
   PubMed Web of Science ®Google Scholar
• Cario G, Izraeli S, Teichert A, et al High interleukin-15 expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS. J Clin Oncol 2007;25:4813–4820.
   PubMed Web of Science ®Google Scholar
• Advani SH, Rao DN, Gopal R, et al Acute lymphoblastic leukemia: end-result analysis of treatment and prognostic factors in Indian patients. Am J Hematol 1983;15:35–43.
   PubMed Web of Science ®Google Scholar
• Advani SH, Iyer RS, Pai SK, et al Four-agent induction/consolidation therapy for childhood acute lymphoblastic leukemia: an Indian experience. Am J Hematol 1992:39;242–248.
   PubMed Web of Science ®Google Scholar
• Pui CH, Cheng C, Leung W, et al Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 2003;349:640–649.
   PubMed Web of Science ®Google Scholar
• Hijiya N, Hudson MM, Lensing S, et al Cumulative incidence of secondary neoplasms as a first event after childhood acute ymphoblastic leukemia. JAMA 2007;297:1207–1215.
   PubMed Web of Science ®Google Scholar
• Pui CH, Campana D, Pei D, et al Treating Childhood Acute Lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009;360:2730–2741.
   PubMed Web of Science ®Google Scholar