291
Views
12
CrossRef citations to date
0
Altmetric
Original Articles: Research

Meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia

, , , , &
Pages 897-905 | Received 13 Nov 2009, Accepted 02 Feb 2010, Published online: 16 Mar 2010

References

  • Xiao Z, Qian L, Liu B, Hao Y. Meisoindigo for the treatment of chronic myelogenous leukaemia. Br J Haematol 2000;111:711–712.
  • Damiens E, Baratte B, Marie D, Eisenbrand G, Meijer L. Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest. Oncogene 2001;20:3786–3797.
  • Suzuki K, Adachi R, Hirayama A, et al Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells. Br J Haematol 2005;130:681–690.
  • Xiao Z, Hao Y, Liu B, Qian L. Indirubin and meisoindigo in the treatment of chronic myelogenous leukemia in China. Leuk Lymphoma 2002;43:1763–1768.
  • Wang Y, Liu B, Peng Y, Xiao Z. Studying of effects of meisoindigo on acute promyelocytic leukemia cell line NB4 in vitro. J Leuk Lymphoma 2005;14:136–139.
  • Chou T-C, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984;22:27–55.
  • Huang MJ, Cheng YC, Liu CR, Lin S, Liu HE. A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia. Exp Hematol 2006;34:1480–1489.
  • Shimizu T, Takeda K. Induction of retinoic acid receptor-alpha by granulocyte macrophage colony stimulating factor in human myeloid leukemia cell lines. Cancer Res 2000;60:4544–4549.
  • Liu L, Berletch JB, Green JG, Pate MS, Andrews LG, Tollefsbol TO. Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation. Mol Cancer Ther 2004;3:1003–1009.
  • Xu D, Popov N, Hou M, et al Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc Natl Acad Sci USA 2001;98:3826–3831.
  • Cerone MA, Londono-Vallejo JA, Autexier C. Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells. Mol Cancer Ther 2006;5:1669–1675.
  • Nakamura M, Masutomi K, Kyo S, et al Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy. Hum Gene Ther 2005;16:859–868.
  • Wu Y-L, Yin T, Sun Y, Wu W-L, Sun G-L. Meisoindigo in combination with imatinib accelerates apoptosis of K562 cells. Acad J Shanghai Sec Med Univ 2005;25:433–436.
  • Marko D, Schatzle S, Friedel A, et al Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells. Br J Cancer 2001;84:283–289.
  • Perabo FG, Frossler C, Landwehrs G, et al Indirubin-3′-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. Anticancer Res 2006;26:2129–2135.
  • Cogswell JP, Cogswell PC, Kuehl WM, et al Mechanism of c-myc regulation by c-Myb in different cell lineages. Mol Cell Biol 1993;13:2858–2869.
  • Xie Y, Liu Y, Ma C, et al Indirubin-3′-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons. Neurosci Lett 2004;367:355–359.
  • Nam S, Buettner R, Turkson J, et al Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells. Proc Natl Acad Sci USA 2005;102:5998–6003.
  • Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM, Aggarwal BB. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. J Biol Chem 2006;281:23425–23435.
  • Konnikova L, Simeone MC, Kruger MM, Kotecki M, Cochran BH. Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells. Cancer Res 2005;65:6516–6520.
  • Nakatake M, Kakiuchi Y, Sasaki N, Murakami-Murofushi K, Yamada O. STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells. Cell Cycle 2007;6:1496–1501.
  • Xiao Z, Wang Y, Lu L, et al Anti-angiogenesis effects of meisoindigo on chronic myelogenous leukemia in vitro. Leuk Res 2006;30:54–59.
  • Mingxin Z, Yan L, Hongbo W, et al The antitumor activity of meisoindigo against human colorectal cancer HT-29 cells in vitro and in vivo. J Chemother 2008;20:728–733.
  • Wee XK, Yeo WK, Zhang B, et al Synthesis and evaluation of functionalized isoindigos as antiproliferative agents. Bioorg Med Chem 2009;17:7562–7571.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.