CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system

References

• Aksoy P, White TA, Thompson M, Chini EN. Regulation of intracellular levels of NAD: a novel role for CD38. Biochem Biophys Res Commun 2006;345:1386–1392.
   PubMed Web of Science ®Google Scholar
• Shubinsky G, Schlesinger M. The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer. Immunity 1997;7:315–324.
   PubMed Web of Science ®Google Scholar
• Hamblin TJ, Orchard JA, Ibbotson RE, et al CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood 2002;99:1023–1029.
   PubMed Web of Science ®Google Scholar
• Morabito F, Mangiola M, Oliva B, et al Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia. Leuk Res 2001;25:927–932.
   PubMed Web of Science ®Google Scholar
• Pittner BT, Jelinek DF, Kay NE. CLL B cells with a bimodal CD38 expression pattern: persistence of bimodal populations despite effective therapy for B-CLL. Leukemia 2004;18:180–182.
   PubMed Web of Science ®Google Scholar
• Malavasi F, Deaglio S, Funaro A, et al Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology. Physiol Rev 2008;88:841–886.
   PubMed Web of Science ®Google Scholar
• Aarhus R, Graeff RM, Dickey DM, Walseth TF, Lee HC. ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP. J Biol Chem 1995;270:30327–30333.
   PubMed Web of Science ®Google Scholar
• Chini EN, Thompson MA, Dousa TP. Enzymatic synthesis of NAADP and ADP-ribosyl cyclases. FASEB J 1996;10:A143.
   Google Scholar
• Dousa TP, Chini EN, Beers KW. Adenine nucleotide diphosphates: emerging second messengers acting via intracellular Ca2+ release. Am J Physiol 1996;271:C1007–C1024.
   PubMed Web of Science ®Google Scholar
• Galione A, Patel S, Churchill GC. NAADP-induced calcium release in sea urchin eggs. Biol Cell 2000;92:197–204.
   PubMed Web of Science ®Google Scholar
• Gu W, Luo J, Brooks CL, Nikolaev AY, Li M. Dynamics of the p53 acetylation pathway. Novartis Found Symp 2004;259:197–205; discussion 205–207, 223–225.
   PubMedGoogle Scholar
• Lee HC. A unified mechanism of enzymatic synthesis of two calcium messengers: cyclic ADP-ribose and NAADP. Biol Chem 1999;380:785–793.
   PubMed Web of Science ®Google Scholar
• Pillai JB, Isbatan A, Imai S, Gupta MP. Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity. J Biol Chem 2005;280:43121–43130.
   PubMed Web of Science ®Google Scholar
• Rongvaux A, Andris F, Van Gool F, Leo O. Reconstructing eukaryotic NAD metabolism. Bioessays 2003;25:683–690.
   PubMed Web of Science ®Google Scholar
• Ziegler M, Niere M. NAD+ surfaces again. Biochem J 2004;382:e5–e6.
   PubMedGoogle Scholar
• Cheung VG, Conlin LK, Weber TM, et al Natural variation in human gene expression assessed in lymphoblastoid cells. Nat Genet 2003;33:422–425.
   PubMed Web of Science ®Google Scholar
• Cheung VG, Spielman RS. Genetics of human gene expression: mapping DNA variants that influence gene expression. Nat Rev Genet 2009;10:595–604.
   PubMed Web of Science ®Google Scholar
• Morley M, Molony CM, Weber TM, et al Genetic analysis of genome-wide variation in human gene expression. Nature 2004;430:743–747.
   PubMed Web of Science ®Google Scholar
• Li L, Fridley B, Kalari K, et al Gemcitabine and cytosine arabinoside cytotoxicity: association with lymphoblastoid cell expression. Cancer Res 2008;68:7050–7058.
   PubMed Web of Science ®Google Scholar
• Pei H, Li L, Fridley BL, et al FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell 2009;16:259–266.
   PubMed Web of Science ®Google Scholar
• Scherf U, Ross DT, Waltham M, et al A gene expression database for the molecular pharmacology of cancer. Nat Genet 2000;24:236–244.
   PubMed Web of Science ®Google Scholar
• Speed T. Background models and GCRMA. Lecture 10, Statistics 246, University of California Berkeley. 2006. Available from: http://www.stat.berkeley.edu/users/terry/Classes/s246.2006/Week10/Week10L1.pdf.
   Google Scholar
• Wu Z, Irizarry RA. Stochastic models inspired by hybridization theory for short oligonucleotide arrays. Proceedings of RECOMB 2004. J Comput Biol 2005;12:882–893.
   PubMed Web of Science ®Google Scholar
• Wu Z, Irizarry RA. A statistical framework for the analysis of microarray probe-level data. Biostatistics Working Papers 73. Baltimore, MD: Johns Hopkins University; 2005.
   Google Scholar
• Wu Z, Irizarry RA, Gentleman R, Murillo FM, Spencer F. A model based background adjustment for oligonucleotide expression arrays. J Am Stat Assoc 2004;99:909–917.
   Web of Science ®Google Scholar
• Ji Y, Olson J, Zhang J, et al Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Res 2008;68:5997–6005.
   PubMed Web of Science ®Google Scholar
• Moyer AM, Salavaggione OE, Wu TY, et al Glutathione S-transferase p1: gene sequence variation and functional genomic studies. Cancer Res 2008;68:4791–4801.
   PubMed Web of Science ®Google Scholar
• Tajima F. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 1989;123:585–595.
   PubMed Web of Science ®Google Scholar
• Ferrero E, Saccucci F, Malavasi F. The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene. Immunogenetics 1999;49:597–604.
   PubMed Web of Science ®Google Scholar
• Yagui K, Shimada F, Mimura M, et al A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. Diabetologia 1998;41:1024–1028.
   PubMed Web of Science ®Google Scholar
• Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT. Mapping determinants of human gene expression by regional and genome-wide association. Nature 2005;437:1365–1369.
   PubMed Web of Science ®Google Scholar
• Soares S, Thompson M, White T, et al NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. Am J Physiol Cell Physiol 2007;292:C227–C239.
   PubMed Web of Science ®Google Scholar