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Leukemia & Lymphoma Volume 53, 2012 - Issue 6
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Letters to the Editor

MLL–ELL fusion gene in two infants with acute monoblastic leukemia and myeloid sarcoma

Etienne de BraekeleerLaboratoire d’Histologie, Cytogénétique et Embryologie, Faculté de Médecine et des Sciences de la Santé, Université de Brest, Brest, France;Institut National de la Santé et de la Recherche Médicale (INSERM), U613, Brest, France
,
Nathalie Douet-GuilbertLaboratoire d’Histologie, Cytogénétique et Embryologie, Faculté de Médecine et des Sciences de la Santé, Université de Brest, Brest, France;Institut National de la Santé et de la Recherche Médicale (INSERM), U613, Brest, France;Service de Cytogénétique, Cytologie et Biologie de la Reproduction, Hôpital Morvan, CHRU Brest, Brest, France
,
Claus MeyerDCAL/Institute of Pharmaceutical Biology/ZAFES, Goethe-University of Frankfurt, Frankfurt/Main, Germany
,
Frédéric MorelLaboratoire d’Histologie, Cytogénétique et Embryologie, Faculté de Médecine et des Sciences de la Santé, Université de Brest, Brest, France;Institut National de la Santé et de la Recherche Médicale (INSERM), U613, Brest, France;Service de Cytogénétique, Cytologie et Biologie de la Reproduction, Hôpital Morvan, CHRU Brest, Brest, France
,
Rolf MarschalekDCAL/Institute of Pharmaceutical Biology/ZAFES, Goethe-University of Frankfurt, Frankfurt/Main, Germany
&
Marc de BraekeleerLaboratoire d’Histologie, Cytogénétique et Embryologie, Faculté de Médecine et des Sciences de la Santé, Université de Brest, Brest, France;Institut National de la Santé et de la Recherche Médicale (INSERM), U613, Brest, France;Service de Cytogénétique, Cytologie et Biologie de la Reproduction, Hôpital Morvan, CHRU Brest, Brest, FranceCorrespondence[email protected]
Pages 1222-1224 | Received 24 Oct 2011, Accepted 05 Dec 2011, Published online: 31 Jan 2012

References

  • Neiman RS, Barcos M, Berard C, . Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer 1981;48:1426–1437.
  • Pileri SA, Ascani S, Cox MC, . Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 2007;21:340–350.
  • Sugimoto Y, Nishii K, Sakakura M, . Acute myeloid leukemia with t(8;21)(q22;q22) manifesting as granulocytic sarcomas in the rhinopharynx and external acoustic meatus at relapse after high-dose cytarabine: case report and review of the literature. Hematol J 2004;5:84–89.
  • Zhang XH, Zhang R, Li Y. Granulocytic sarcoma of abdomen in acute myeloid leukemia patient with inv(16) and t(6;17) abnormal chromosome: case report and review of literature. Leuk Res 2010;34:958–961.
  • Xavier SG, Fagundes EM, Hassan R, . Granulocytic sarcoma of the small intestine with CBFbeta/MYH11 fusion gene: report of an aleukaemic case and review of the literature. Leuk Res 2003;27: 1063–1066.
  • Sam TN, Kersey JH, Linabery AM, . MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: a Children's Oncology Group (COG) study. Pediatric Blood Cancer 2011 Jul 28. [Epub ahead of print]
  • Douet-Guilbert N, Morel F, Le Bris MJ, . Rearrangement of MLL in a patient with congenital acute monoblastic leukemia and granulocytic sarcoma associated with a t(1;11)(p36;q23) translocation. Leuk Lymphoma 2005;46:143–146.
  • Meyer C, Schneider B, Reichel M, . Diagnostic tool for the identification of MLL rearrangements including unknown partner genes. Proceedings of the National Academy of Sciences USA 2005; 102:449–454.
  • De Braekeleer E, Meyer C, Douet-Guilbert N, . A complex 1;19;11 translocation involving the MLL gene in a patient with congenital acute monoblastic leukemia identified by molecular and cytogenetic techniques. Ann Hematol 2009;88:795–797.
  • Byrd JC, Edenfield J, Shields DJ, . Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: a clinical review. J Clin Oncol 1995;13:1800–1816.
  • Breccia M, Mandelli F, Petti MC, . Clinico-pathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution. Leuk Res 2004;28:1165–1169.
  • De Braekeleer M, Morel F, Le Bris MJ, . The MLL gene and translocations involving chromosomal band 11q23 in acute leukemia. Anticancer Res 2005;25:1931–1944.
  • Meyer C, Kowarz E, Hofmann J, . New insights to the MLL recombinome of acute leukemias. Leukemia 2009;23: 1490–1499.
  • Ouansafi I, Arabadjief M, Mathew S, . Myeloid sarcoma with t(11;19)(q23;p13.3) (MLL-ELL) in the uterine cervix. Br J Haematol 2011;153:679.
  • De Braekeleer E, Meyer C, Douet-Guilbert N, . Identification of MLL partner genes in 27 patients with acute leukemia from a single cytogenetic laboratory. Mol Oncol 2011;5:555–563.

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