Vascular endothelial growth factor receptor-3 expression in mycosis fungoides

References

• Kim EJ, Hess S, Richardson SK, . Immunopathogenesis and therapy of cutaneous T cell lymphoma. J Clin Invest 2005;115:798–812.
   PubMed Web of Science ®Google Scholar
• Lutzner M, Edelson R, Schein P, . Cutaneous T-cell lymphomas:the Sezary syndrome, mycosis fungoides, and related disorders. Ann Intern Med 1975;83:534–552.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Odum N, Geisler C, . Regulatory T cells and immunodeficiency in mycosis fungoides and Sezary syndrome. Leukemia 2012;26:424–432.
   PubMed Web of Science ®Google Scholar
• Bradford PT, Devesa SS, Anderson WF, . Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases. Blood 2009;113:5064–5073.
   PubMed Web of Science ®Google Scholar
• Zhao WL. Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways. Leukemia 2010;24:13–21.
   PubMed Web of Science ®Google Scholar
• Nielsen M, Kaltoft K, Nordahl M, . Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides:tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc Natl Acad Sci USA 1997;94:6764–6769.
   PubMed Web of Science ®Google Scholar
• Lauenborg B, Kopp K, Krejsgaard T, . Programmed cell death-10 enhances proliferation and protects malignant T cells from apoptosis. APMIS 2010;118:719–728.
   Google Scholar
• Sommer VH, Clemmensen OJ, Nielsen O, . In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3. Leukemia 2004;18:1288–1295.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Vetter-Kauczok CS, Woetmann A, . Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma. Blood 2009;113:5896–5904.
   PubMedGoogle Scholar
• Kamstrup MR, Gjerdrum LM, Biskup E, . Notch1 as a potential therapeutic target in cutaneous T-cell lymphoma. Blood 2010;116:2504–2512.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Ralfkiaer U, Clasen-Linde E, . Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway. J Invest Dermatol 2011;131:1331–1338.
   PubMed Web of Science ®Google Scholar
• Kopp KL, Kauczok CS, Lauenborg B, . COX-2-dependent PGE(2) acts as a growth factor in mycosis fungoides (MF). Leukemia 2010;24:1179–1185.
   PubMed Web of Science ®Google Scholar
• Kiessling MK, Klemke CD, Kaminski MM, . Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma. Cancer Res 2009;69:2365–2374.
   PubMed Web of Science ®Google Scholar
• Ralfkiaer U, Hagedorn PH, Bangsgaard N, . Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL). Blood 2011;118:5891–5900.
   PubMed Web of Science ®Google Scholar
• Ballabio E, Mitchell T, van Kester MS, . MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential. Blood 2010;116:1105–1113.
   PubMed Web of Science ®Google Scholar
• Mazur G, Wozniak Z, Wrobel T, . Increased angiogenesis in cutaneous T-cell lymphomas. Pathol Oncol Res 2004;10:34–36.
   PubMed Web of Science ®Google Scholar
• Karpova MB, Fujii K, Jenni D, . Evaluation of lymphangiogenic markers in Sezary syndrome. Leuk Lymphoma 2011;52:491–501.
   PubMed Web of Science ®Google Scholar
• Vacca A, Moretti S, Ribatti D, . Progression of mycosis fungoides is associated with changes in angiogenesis and expression of the matrix metalloproteinases 2 and 9. Eur J Cancer 1997;33: 1685–1692.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Vetter-Kauczok CS, Woetmann A, . Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma. Leukemia 2006;20:1759–1766.
   PubMed Web of Science ®Google Scholar
• He Y, Zhang H, Yu L, . Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal 2010;3:ra26.
   Web of Science ®Google Scholar
• Woetmann A, Lovato P, Eriksen KW, . Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins. Blood 2007;109:3325–3332.
   Google Scholar
• Hofmann B, Odum N, Platz P, . Immunological studies in acquired immunodeficiency syndrome. Functional studies of lymphocyte subpopulations. Scand J Immunol 1985;21:235–243.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Kopp K, Ralfkiaer E, . A novel xenograft model of cutaneous T-cell lymphoma. Exp Dermatol 2010;19:1096–1102.
   PubMed Web of Science ®Google Scholar
• Eriksen KW, Lovato P, Skov L, . Increased sensitivity to interferon-alpha in psoriatic T cells. J Invest Dermatol 2005;125: 936–944.
   PubMed Web of Science ®Google Scholar
• Krejsgaard T, Gjerdrum LM, Ralfkiaer E, . Malignant Tregs express low molecular splice forms of FOXP3 in Sezary syndrome. Leukemia 2008;22:2230–2239.
   PubMed Web of Science ®Google Scholar
• Dias S, Choy M, Alitalo K, . Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 2002;99:2179–2184.
   PubMed Web of Science ®Google Scholar
• Su JL, Yen CJ, Chen PS, . The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer 2007;96:541–545.
   PubMed Web of Science ®Google Scholar
• Khan O, La Thangue NB. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol Cell Biol 2012;90:85–94.
   PubMed Web of Science ®Google Scholar
• Rangwala S, Zhang C, Duvic M. HDAC inhibitors for the treatment of cutaneous T-cell lymphomas. Future Med Chem 2012;4:471–486.
   PubMedGoogle Scholar
• Fantin VR, Loboda A, Paweletz CP, . Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma. Cancer Res 2008;68: 3785–3794.
   PubMed Web of Science ®Google Scholar
• Kurenova EV, Hunt DL, He D, . Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo. Cell Cycle 2009;8: 2266–2280.
   PubMed Web of Science ®Google Scholar
• Chien MH, Ku CC, Johansson G, . Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGFR-3/JNK/AP-1 pathway. Carcinogenesis 2009;30:2005–2013.
   PubMed Web of Science ®Google Scholar
• Pollina EA, Legesse-Miller A, Haley EM, . Regulating the angiogenic balance in tissues. Cell Cycle 2008;7:2056–2070.
   PubMed Web of Science ®Google Scholar
• Skobe M, Hawighorst T, Jackson DG, . Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 2001;7:192–198.
   PubMed Web of Science ®Google Scholar
• Campbell JJ, Clark RA, Watanabe R, . Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors. Blood 2010;116:767–771.
   PubMed Web of Science ®Google Scholar
• Huang C, Huang R, Chang W, . The expression and clinical significance of pSTAT3, VEGF and VEGF-C in pancreatic adenocarcinoma. Neoplasma 2012;59:52–61.
   PubMed Web of Science ®Google Scholar
• Ristimaki A, Narko K, Enholm B, . Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J Biol Chem 1998;273: 8413–8418.
   PubMed Web of Science ®Google Scholar
• Hosono K, Suzuki T, Tamaki H, . Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation. Arterioscler Thromb Vasc Biol 2011;31: 1049–1058.
   PubMed Web of Science ®Google Scholar
• Kluger MS, Colegio OR. Lymphangiogenesis linked to VEGF-C from tumor-associated macrophages: accomplices to metastasis by cutaneous squamous cell carcinoma?J Invest Dermatol 2011;131:17–19.
   PubMed Web of Science ®Google Scholar
• Litvinov IV, Jones DA, Sasseville D, . Transcriptional profiles predict disease outcome in patients with cutaneous T-cell lymphoma. Clin Cancer Res 2010;16:2106–2114.
   PubMed Web of Science ®Google Scholar