155
Views
14
CrossRef citations to date
0
Altmetric
Research Articles

The clinical behavior of 124 leukemic ovarian tumors: clues for improving the poor prognosis

Pages 1430-1436 | Received 29 Jun 2012, Accepted 27 Oct 2012, Published online: 24 Dec 2012

References

  • Cunningham I. A basis for updating our approach to resistant acute leukemia. Am J Hematol 2012;87:251–257.
  • Drinkard LC, Waggoner S, Stein RN, et al. Acute myelomonocytic leukemia with abnormal eosinophils presenting as an ovarian mass: a report of two cases and a review of the literature. Gynecol Oncol 1995;56:307–311.
  • Terek MC, Ozkinay E, Zekioglu O, et al. Acute leukemia in pregnancy with ovarian metastasis: a case report and review of the literature. Int J Gynecol Cancer 2003;13:904–908.
  • Bolaman Z, Kadikoylu G, Kafkas S, et al. Granulocytic sarcoma of the ovotestis: an association of myelodysplastic syndrome and hermaphroditism. Leuk Lymphoma 2004;45:1285–1287.
  • Bigatti G, Rosales M, Salomoni G, et al. Sarcoma granulocitico in una paziente di 46 anni sottoposta a LAVH. Casi Clin Oncol 2003; 7:5–8.
  • Gangadharan VP, Sasidharan K, Preetha S, et al. Chronic systemic (hepatosplenic) candidiasis in a patient with granulocytic sarcoma. Am J Clin Oncol 2000;23:562–563.
  • Inoue S, Limsuwan A, McQueen R. Spontaneous resolution of myelofibrosis and pancytopenia followed by the development of acute myeloid leukemia with an extramedullary mass. J Pediatr Hematol Oncol 1998;20:268–270.
  • Garcia MG, Deavers MT, Knoblock RJ, et al. Myeloid sarcoma involving the gynecologic tract: a report of 11 cases and review of the literature. Am J Clin Pathol 2006;125:783–790.
  • Pagano L, Voso MT, La Rocca LM, et al. Granuloblastic masses in the breast: report of two cases. Haematologia (Budap) 1993;25: 287–291.
  • Ruiz-Argüelles GJ. Unpublished case. 2010.
  • Čemerikić-Martinović V, Perunič M, Tomin D, et al. Pre-leukemic granulocytic sarcoma of the female genital tract: report of two cases. Arch Oncol 2002;12(Suppl. 1): Abstract 195.
  • Case records of the Massachusetts General Hospital. Case 22-1990. N Engl J Med 1990;32:1585–1594.
  • Tamaki H, Yoshihara S, Fujioka T, et al. Molecular detection of AML1-MTG8-positive cells in peripheral blood from a patient with isolated extramedullary relapse of t(8;21) acute myeloid leukemia. Leukemia 2009;23:424–426.
  • Wang X, Liu H, Wu Z, et al. A case of acute promyelocytic leukemia presenting with a nonleukemic granulocytic sarcoma of the ovary, with subsequent development of acute myeloid leukemia associated with t(8;21). Leuk Res 2009;33:580–582.
  • Avigdor S, du Rouchet E, Michenet P, et al. The presence of an ovarian granulocytic sarcoma concurrent with a type M2 acute myeloblastic leukemia: a case. J Gynecol Obstet Biol Reprod (Paris) 1991; 20:797–801.
  • Hernandez J-A, Navarro JT, Rozman M, et al. Primary myeloid sarcoma of the gynecologic tract: a report of two cases progressing to acute myeloid leukemia. Leuk Lymphoma 2002;43:2151–2153.
  • Johansson B, Fioretos T, Kullendorff CM, et al. Granulocytic sarcoma in body cavities in childhood acute myeloid leukemias with 11q23/MLL rearrangements. Genes Chromosomes Cancer 2000;27: 136–142.
  • Kumar M, Watanabe M, Singh V, et al. Infant with granulocytic sarcoma of the ovary: an unusual case presentation of acute myelogenous leukemia (M6). Clin Leukemia 2007;1:247–250.
  • Lacotte-Thierry L, Thierry A, Brizard F, et al. Ovarian sarcoma and acute myelogenous leukaemia. Hematol J 2001;2:404–405.
  • Schmid C, Lange C, Salat C, et al. Treatment of recurrent acute leukemia after marrow transplantation with donor cells and GM-CSF. Blood 1999;94(Suppl. 1): Abstract 668.
  • Szomor A, Passweg JR, Tichelli A, et al. Myeloid leukemia and myelodysplastic syndrome relapsing as granulocytic sarcoma (chloroma) after allogeneic bone marrow transplantation. Ann Hematol 1997;75:239–241.
  • Wang H-Y, Huang LJ, Liu Z, et al. Erythroblastic sarcoma presenting as bilateral ovarian masses in an infant with pure erythroid leukemia. Hum Pathol 2011;42:749–758.
  • Berretta R, Barone A, Rolla M, et al. Isolated ovarian relapse of pre-B acute lymphoblastic leukemia: a case report. J Pediatr Adolescent Gynecol 2009;22:e65–e68.
  • Kim JW, Cho MK, Kim CH, et al. Ovarian and multiple lymph nodes recurrence of acute lymphoblastic leukemia: a case report and review of literature. Pediatr Surg Int 2008;24:1269–1273.
  • Kim M-A, Lee G-W, Maeng K-Y. An unusual presenting feature of precursor T-cell acute lymphoblastic leukemia/lymphoma. Ann Hematol 2005;84:553–554.
  • Kang BW, Joon JH, Chae YS, et al. Pre-emptive treatment with nilotinib after second allogeneic transplantation in a Philadelphia chromosome-positive acute lymphoblastic leukemia patient with high risk of relapse. Acta Haem (Basel) 2010;123:242–247.
  • Singhal MK, Krishnan V, Singh S, et al. Isolated ovarian relapse in a 68-year-old woman with acute lymphoblastic leukemia. J Clin Oncol 2009;28:e73–e74.
  • Chow CD, Dalla-Pozza L, Gottlieb DJ, et al. Two cases of very late relapsing childhood ALL carrying the TEL:AML1 fusion gene. Leukemia 1999;13:1893–1899.
  • Ly-Sunnaram B, Henry C, Gandemer V, et al. Late ovarian relapse of TEL/AML1 positive ALL confirming that TEL deletion is a secondary event in leukemogenesis. Leuk Res 2005;29:1089–1094.
  • Bellaaj H, Moussa A, Gouiaa N, et al. Isolated extramedullary adnexal relapse of acute lymphoblastic leukemia: a case report. Arch Pediatr 2009;16:1016–1020.
  • Heaton DC, Duff GB. Ovarian relapse in a young woman with acute lymphoblastic leukaemia. Am J Hematol 1989;30:42–43.
  • Hinkle AS, Dinndorf PA, Bulas DI, et al. Relapse of acute lymphoblastic leukemia in the inferior rectus muscle of the eye. Cancer 1994;73:1757–1760.
  • Kook H, Kang HK, Huang TJ, et al. Isolated ovarian relapse of acute lymphoblastic leukemia: a case report with magnetic resonance images. Chonnam J Med Sci 1994;7:121–126.
  • Moon HW, Huh HJ, Kang ES, et al. A case of ovarian-relapse sparing of the marrow in a patient with acute T cell lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation. Korean J Lab Med 2003;23:78–81.
  • Castagnola C, Lunghi M, Caberlon S, et al. Long-term outcome of Ph-negative acute lymphoblastic leukaemia in adults: a single centre experience. Acta Hematol 2005;113:234–240.
  • Marra R, Pagano L, Storti S, et al. Ovarian granulocytic sarcoma with central nervous system involvement. Tumori 1986;72:335–338.
  • Oliva E, Ferry JA, Young RH, et al. Granulocytic sarcoma of the female genital tract: a clinicopathologic study of 11 patients. Am J Surg Pathol 1997;21:1156–1165.
  • Stavem P, Evensen SA, Torkildsen EM, et al. Ovarian relapse in a young woman with acute lymphoblastic leukemia. Am J Hematol 1989;32:155.
  • Case records of the Massachusetts General Hospital. Case 45–1981. N Engl J Med 1981;305:1135–1146.
  • Gardais J, Marie M, Bertrand G. Chlorome à localisations génitales multiples. Sem Hôp Paris 1975;51:609–616.
  • Fadilah SA, Goh KY. Breast and ovarian recurrence of acute lymphoblastic leukaemia after allogeneic peripheral blood haematopoietic stem cell transplantation. Singapore Med J 2009;50:e407–e409.
  • Aguilar RCT, Pozzi DHB, Chamone DAF. Granulocytic sarcoma of the ovary in a nonleukemic patient. Haematologica 1993;78:53–55.
  • Hayashi T, Kimura M, Satoh S, et al. Early detection of AML1/MTG8 fusion mRNA by RT-PCR in the bone marrow cells from a patient with isolated granulocytic sarcoma. Leukemia 1998;12:1501–1503.
  • Mehta J, Kane S. Primary granulocytic sarcoma of ovary—a rare presentation. Leuk Lymphoma 2004;45:845–847.
  • Pressler H, Horny HP, Wolf A, et al. Isolated granulocytic sarcoma of the ovary: histologic, electron microscopic, and immunohistochemical findings. Int J Gynecol Pathol 1992;11:68–74.
  • Reynaud P, LeBouedec G, Dechelotte P, et al. Rare tumors of the cervix: three case reports: rhabdomyosarcoma, granulocytic sarcoma and lymphoma. J Gynecol Obstet Biol Reprod (Paris) 1995;24:30–34.
  • Schäfer RJ, Hill K, Reitz H. Myelosarkom (leukotishes sarcom) des ovars vor manifestation einer leukose. Zentralbl Allg Pathol 1974;118:467–472.
  • Stefenelli T, Linkesch W, Radaszkiewicz T. Myelosarcoma of the ovary. Wien Klin Wochenschr 1991;103:717–718.
  • Jung JY, Jung MJ, Oh JY, et al. Primary granulocytic sarcoma of ovary: a rare case report. J Womens Med 2010;3:81–83.
  • Jung SE, Chun KA, Park SH, et al. MR findings in ovarian granulocytic sarcoma. Br J Radiol 1999;72:301–303.
  • Chorlton I, Norris HJ, King FM. Malignant reticuloendothelial disease involving the ovary as a primary manifestation: a series of 19 lymphomas and 1 granulocytic sarcoma. Cancer 1974;34:397–407.
  • Au WY, Ma SK, Chan ACL, et al. Near tetraploidy in three cases of acute myeloid leukemia associated with mediastinal granulocytic sarcoma. Cancer Genet Cytogenet 1998;102:50–53.
  • Astruc J, Janbon J, Janbon F, et al. Rôle de l'ovariectomie au cours d'une réticulose histio-monocytaire à localisations mammaires et ovariennes après un stade initial de leucose monocytaire. J Med Montpellier 1970;5:445–449.
  • Bauters F, Roussy M, Leduc M, et al. Les localisations ovariennnes spécifiques au cours des leucémies aiguës (à propos de 3 observations). Lille Med 1978;23:151–157.
  • Cecalupo AJ, Frankel LS, Sullivan MP. Pelvic and ovarian extramedullary leukemic relapse in young girls: a report of four cases and review of the literature. Cancer 1982;50:587–593.
  • Sonoki T, Iwanaga E, Mitsuya H, et al. Ovarian relapse seven years after bone marrow transplantation for B-cell acute lymphoblastic leukemia: an unusual Krukenberg tumor. Am J Hematol 2005;80:75–76.
  • Johnson FL, Thomas ED, Clark BS, et al. A comparison of marrow transplantation with chemotherapy for children with acute lymphoblastic leukemia in second or subsequent remission. New Engl J Med 1981;305:846–851.
  • Lane DM, Birdwell RL. Ovarian leukemia detected by pelvic sonography. A case report. Cancer 1986;58:2338–2342.
  • Chu J-Y, Cradock TV, Danis RK, et al. Ovarian tumor as manifestation of relapse in acute lymphoblastic leukemia. Cancer 1981;48:377–379.
  • Okamura M, Akabori T, Takeuchi S, et al. A case of young woman with giant ovarian tumor as the manifestation of leukemic recurrence. Nippon Gan Chiryo Gakkai Shi 1990;25:1032–1037.
  • Pais RC, Kim TH, Zwiren GT, et al. Ovarian tumors in relapsing acute lymphoblastic leukemia: a review of 23 cases. J Pediatr Surg 1991;26:70–74.
  • Turial S, Karabul N, Gutjahr P, et al. Ovarian tumours: late extramedullary recurrence. Eur J Pediatr Surg 2009;19:184–186.
  • Qamruddin K, Hassan S, Khurshid M. Case of pelvic relapse in a child suffering from acute lymphoblastic leukemia. J Pak Med Assoc 1995;45:193–194.
  • Scrideli CA, Kashima S, Cipolloti R, et al. Clonal evolution as the limiting factor in the detection of minimal residual disease by polymerase chain reaction in children in Brazil with acute lymphoid leukemia. J Pediatr Hematol Oncol 2002;24:364–367.
  • Shirkhoda A, Eftekhari F, Frankel LS, et al. Diagnosis of leukemic relapse in the pelvic soft tissues of juvenile females. J Clin Ultrasound 1986;14:191–195.
  • Slasky BS, Straub WH, Deutsch M. Acute lymphocytic leukemia of the ovary: the value of sonography. J Comput Tomogr 1982;6:161–165.
  • Sonta-Jakimczyk D, Sroczynska M, Koehler M, et al. Ovarian recurrence of lymphoblastic leukemia in an 11-year old 41 months after termination of chemotherapy. Pediatr Pol 1985;60:543–545.
  • Vasilyev AV, Mayakova SA. Tumourous nodular growth in acute lymphoblastic leukemia in children. Arkh Patol 1985;48:72–74.
  • Cantwell B, Cantwell D, Fennelly JJ. Uterine and ovarian leukaemic relapse during bone marrow remission in acute lymphoblastic leukaemia. Postgrad Med J 1982;58:724–725.
  • Obeid D, Cotter P, Sturdee DW. Acute leukaemia relapse presenting as ovarian tumour. Br J Obstet Gynaecol 1979;86:578–580.
  • Zarrouk SO, Kim TH, Hargreaves HK, et al. Leukemic involvement of the ovaries in childhood acute lymphocytic leukemia. J Pediatr 1982;100:422–424.
  • Bickers GH, Siebert JJ, Anderson JC, et al. Sonography of ovarian involvement in childhood acute lymphocytic leukemia. AJR Am J Roentgenol 1981;137:399–401.
  • Bohinjec J. Extramedullary tumor-like recurrence of acute leukemia. Wien Z Inn Med 1973;54:473–478.
  • Bunin NJ, Pui C-H, Hustu HO, et al. Unusual extramedullary relapses in children with acute lymphoblastic leukemia. J Pediatr 1986;109:665–668.
  • Chessells JM, Veys P, Kempski H, et al. Long-term follow-up of relapsed childhood acute lymphoblastic leukaemia. Br J Haematol 2003;123:396–405.
  • Demiroglu H, Ozcebe OI, Akcan Y, et al. Ovarian relapse and cutaneous involvement in a case of acute lymphoblastic leukaemia. Acta Haematol 1994;92:56.
  • Ellegaard J, Bendix-Hansen K, Boesen AM, et al. Breast tumour as a first manifestation of extramedullary relapse in acute lymphoblastic leukaemia. Scand J Haematol 1984;33:288–294.
  • Wyld PJ, Lilleyman JS. Ovarian disease in childhood lymphoblastic leukaemia. Acta Haematol (Basel) 1983;69:278–280.
  • Morgan ER, Labotka RJ, Gonzalez-Crussi F, et al. Ovarian granulocytic sarcoma as the primary manifestation of acute infantile myelomonocytic leukemia. Cancer 1981;48:1819–1824.
  • Osborne BM, Robboy SJ. Lymphomas or leukemia presenting as ovarian tumors. An analysis of 42 cases. Cancer 1983;52:1933–1943.
  • Kobayashi M, Ohno R, Yamada K, et al. A case of granulocytic sarcoma of the ovary with minimal involvement of the bone marrow, liver and spleen. Rinsho Ketsueki 1977;18:1154–1159.
  • Magliocco AM, Demetrick DJ, Jones AR, et al. Granulocytic sarcoma of the ovary. An unusual case presentation. Arch Pathol Lab Med 1991;115:830–834.
  • Tripathi R, Sharma B, Chaturvedi KU, et al. Granulocytic sarcoma of the female genital tract: report of a case with an unusual presentation. Gynecol Obstet Invest 2005;59:189–191.
  • Yavuz S, Paydas S, Disel U, et al. Ovarian granulocytic sarcoma. Leuk Lymphoma 2004;45:183–185.
  • Ballon SC, Donaldson RC, Berman ML, et al. Myeloblastoma (granulocytic sarcoma) of the ovary. Arch Pathol Lab Med 1978;102: 474–476.
  • Chan EY, Glassberg AB, Rosenblum MA. Chloroma: rare manifestation of acute leukemia. Postgrad Med 1980;67:125–130.
  • Yamamoto K, Akiyama H, Maruyama T, et al. Granulocytic sarcoma of the ovary in patients with acute myelogenous leukemia. Am J Hematol 1991;38:223–225.
  • Amadori G, Brigato G, Cordiano V, et al. Pelvic and mammary Burkitt-like lymphoma with simultaneous development of leukemia. Gynecol Oncol 1987;26:246–250.
  • Asai S, Miyachi H, Kubota M, et al. Ultrasonographic appearance and clinical implication of bilateral breast infiltration with leukemia cells. In: Ueno ET, Shiina T, Kubota M, et al, editors. Research and development in breast ultrasound. Tokyo: Springer-Verlag; 2005. pp. 185–189.
  • Habek D, Cerkez Habek J, Galic J, et al. Acute abdomen as first symptom of acute leukemia. Arch Gynecol Obstet 2004;270: 122–123.
  • Till H, Muensterer O, Graubner U. Laparoscopic adnexectomy of a persistent ovarian tumor in a girl with acute lymphoblastic leukemia relapse. Pediatr Hematol Oncol 2003;20:417–420.
  • Choudhry VP, Arya LS. The ovary as sanctuary site in childhood acute lymphocytic leukemia. Cancer J (Villejuif) 1989;2:401–402.
  • deMello FG, Montenegro MR, Macedo AR, et al. Ovarian tumor as an unusual manifestation of treated acute lymphoblastic leukemia. AMB Rev Assoc Med Bras 1979;25:323–325.
  • Vernant JP, Marit G, Maraninchi D, et al. Allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia in first complete remission. J Clin Oncol 1988;6:227–231.
  • Kawano Y, Hosoya R, Nishimura K. Torsion of ovary with leukemic infiltration. Acta Paediatr Jpn 1985;27:275–276.
  • Kawano S, Tatsumi E, Yoneda N, et al. Leukemic proliferation of myeloblasts after granulocyte colony-stimulating factor administration following lymphoma-type chemotherapy in a patient with uterine cervix myeloblastoma. Am J Hematol 1992;40:155–156.
  • Muss HB, Moloney WC. Chloroma and other myeloblastic tumors. Blood 1973;42:721–728.
  • Buchanan GR, Boyett JM, Pollock BH, et al. Improved treatment results in boys with overt testicular relapse during or shortly after initial therapy for acute lymphoblastic leukemia. A Pediatric Oncology Group study. Cancer 1991;68:48–55.
  • Finklestein JZ, Dyment PG, Hammond GD. Leukemic infiltration of the testes during bone marrow remission. Pediatrics 1969;43: 1042–1045.
  • Sullivan MP, Hrgovic M. Extramedullary leukemia. In: Sutow WW, Vietti TJ, Fernbach DJ, editors. Clinical pediatric oncology. St. Louis: C.V. Mosby Co.; 1977. p. 386.
  • Chateil JF, Arboucalot F, Pérel Y, et al. Breast metastases in adolescent girls: US findings. Pediatr Radiol 1998;28:832–835.
  • Jubert C. Unpublished case. 2011.
  • Dock G, Warthin AS. A new case of chloroma with leukemia. With a study of cases reported since 1893. Trans Assoc Am Physicians 1904;19:64–115.
  • Kim TH, Brynes RK, Lui VK-S, et al. Pretreatment testicular biopsy in childhood acute lymphocytic leukaemia. Lancet 1981;2: 657–658.
  • Stölzel F, Röllig C, Radke J, et al. 18F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia. Haematologica 2011;96: 1552–1556.
  • Ozcan Kara P, Kara Gedik G, Sari O, et al. Acute myeloid leukemia detected on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in a patient with fever of unknown origin. Rev Esp Med Nucl 2011;30:115–116.
  • Cunningham I. Extramedullary sites of leukemia relapse after transplant. Leuk Lymphoma 2006;47:1754–1767.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.