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Letter

Patients with myelodysplastic syndrome and two clones with different interstitial deletions of the long arm of chromosome 5

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Pages 2314-2317 | Received 14 Nov 2012, Accepted 28 Jan 2013, Published online: 04 Apr 2013

References

  • Braulke F, Schanz J, Steffens R, et al. Two different del(5q) clones in a patient with myelodysplastic syndrome. Leuk Lymphoma 2011;52:1811–1814.
  • Douet-Guilbert N, Basinko A, Eveillard JR, et al. Three rearrangements of chromosome 5 in a patient with myelodysplastic syndrome: an atypical deletion 5q, a complex intrachromosomal rearrangement of chromosome 5, and a paracentric inversion of chromosome 5. Cancer Genet Cytogenet 2010;203:303–308.
  • Evers C, Beier M, Poelitz A, et al. Molecular definition of chromosome arm 5q deletion end points and detection of hidden aberrations in patients with myelodysplastic syndromes and isolated del(5q) using oligonucleotide array CGH. Genes Chromosomes Cancer 2007;46:1119–1128.
  • Swerdlow S, Campo E, Harris N, et al, editors. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon: IARC; 2008.
  • Boultwood J. Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome. Blood 2002;99:4638–4641.
  • Patnaik MM, Lasho TL, Finke CM, et al. WHO-defined ‘myelodysplastic syndrome with isolated del(5q)’ in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations. Leukemia 2010;24:1283–1289.

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