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Letter

Acute myeloid leukemia with a novel t(8;21) variant: paracentric inversion-associated ins(21;8)

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Pages 441-443 | Received 20 Mar 2013, Accepted 27 Apr 2013, Published online: 14 Jun 2013

References

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  • Specchia G, Albano F, Anelli L, et al. Insertions generating the 5’RUNX1/3’CBFA2T1 gene in acute myeloid leukemia cases show variable breakpoints. Genes Chromosomes Cancer 2004;41:86–91.
  • Rucker FG, Bullinger L, Gribov A, et al. Molecular characterization of AML with ins(21;8)(q22;q22q22) reveals similarity to t(8;21) AML. Genes Chromosomes Cancer 2011;50:51–58.
  • Kazama H, Aoyama M, Sameshima Y, et al. [Acute myelogenous leukemia with ins(21;8) expressing AML-1-MTG8 fusion transcript]. Rinsho Ketsueki 1996;37:1297–1302.
  • Yamazaki E, Ogawa K, Harano H, et al. [Acute myelocytic leukemia with ins(21;8)(q22;q13q22) presenting with AML1/MTG8 chimeric mRNA]. Rinsho Ketsueki 2000;41:745–749.
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  • Ishii Y, Sashida G, Takaku TI, et al. Cryptic chromosomal anomaly in a patient with acute myeloid leukemia leading to AML1/ETO fusion with unfavorable prognostic factors. Cancer Genet Cytogenet 2005;160:94–95.
  • Park TS, Song J, Lee KA, et al. Paracentric inversion-associated t(8;21) variant in de novo acute myelogenous leukemia: characteristic patterns of conventional cytogenetics, FISH, and multicolor banding analysis. Cancer Genet Cytogenet 2008;183:72–76.
  • Harrison CJ, Radford-Weiss I, Ross F, et al. Fluorescence in situ hybridization analysis of masked (8;21)(q22;q22) translocations. Cancer Genet Cytogenet 1999;112:15–20.
  • Grimwade D. Screening for core binding factor gene rearrangements in acute myeloid leukemia. Leukemia 2002;16: 964–969.

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