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Leukemia & Lymphoma Volume 56, 2015 - Issue 9
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Letters to the Editor

A cryptic submicroscopic deletion of 5’ MLF1–3’ NPM1 segment on derivative chromosome 3 in a patient with acute myeloid leukemia with t(3;5)(q25;q35)

Man GaoDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;Department of Pediatrics, the First Hospital of Jilin University, Jilin, P. R. China
,
Guanjun WangCancer Center, the First Hospital of Jilin University, Jilin, P. R. ChinaCorrespondence[email protected] [email protected]
,
Xianfu WangDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
,
Young Mi KimDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
,
Xianglan LuDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
,
Jin LuDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;Cancer Center, the First Hospital of Jilin University, Jilin, P. R. China
,
Yue GuDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;Department of Pulmonology, the First Hospital of Jilin University, Jilin, P. R. China
,
Hui PangDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
,
Jiyun LeeDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;Department of Pathology, College of Medicine, Korea University, Seoul, South Korea
,
Andrea SternenbergerDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
&
Shibo LiDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USACorrespondence[email protected] [email protected]
 show all
Pages 2735-2738 | Received 15 Jul 2014, Accepted 09 Jan 2015, Published online: 11 Feb 2015

References

  • Bacher U, Schnittger S, Kern W, et al. The incidence of submicroscopic deletions in reciprocal translocations is similar in acute myeloid leukemia, BCR-ABL positive acute lymphoblastic leukemia, and chronic myeloid leukemia. Haematologica 2005;90:558–559.
  • Moon HW, Chang YH, Kim TY, et al. Incidence of submicroscopic deletions vary according to disease entities and chromosomal translocations in hematologic malignancies: investigation by fluorescence in situ hybridization. Cancer Genet Cytogenet 2007; 175:166–168.
  • Lee YK, Kim YR, Min HC, et al. Deletion of any part of the BCR or ABL gene on the derivative chromosome 9 is a poor prognostic marker in chronic myelogenous leukemia. Cancer Genet Cytogenet 2006;166:65–73.
  • Godon C, Proffitt J, Dastugue N, et al. Large deletions 5’ to the ETO breakpoint are recurrent events in patients with t(8;21) acute myeloid leukemia. Leukemia 2002;16:1752–1754.
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