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Leukemia & Lymphoma Volume 57, 2016 - Issue 1
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Letters to the Editor

Long-term complete remission by infusion of ex vivo-expanded donor-derived CD4+ lymphocytes for treating an early relapse of Hodgkin lymphoma after cord blood transplantation

Tomoya MutoDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Chikako OhwadaDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Atsuko YamazakiDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Yasumasa SugitaDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Shokichi TsukamotoDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Shio SakaiDepartment of Hematology, Chiba University Hospital, Chiba, Japan;Division of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan
,
Yusuke TakedaDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Naoya MimuraDepartment of Hematology, Chiba University Hospital, Chiba, Japan;Division of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan
,
Masahiro TakeuchiDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Emiko SakaidaDepartment of Hematology, Chiba University Hospital, Chiba, Japan
,
Tohru IsekiDepartment of Hematology, Chiba University Hospital, Chiba, Japan;Division of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan
,
Norio ShimizuDepartment of Virology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
,
Tomohiro MorioDepartment of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan
&
Chiaki NakasekoDepartment of Hematology, Chiba University Hospital, Chiba, JapanCorrespondence[email protected]
 show all
Pages 230-232 | Received 01 Mar 2015, Accepted 12 Apr 2015, Published online: 18 Jun 2015

References

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  • Yoshida H, Kusuki S, Hashii Y, et al. Ex vivo-expanded donor CD4(+) lymphocyte infusion against relapsing neuroblastoma: a transient graft-versus-tumor effect. Pediatr Blood Cancer 2009;52: 895–897.
  • Tomizawa D, Aoki Y, Nagasawa M, et al. Novel adopted immunotherapy for mixed chimerism after unrelated cord blood transplantation in Omenn syndrome. Eur J Haematol 2005;75:441–444.
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  • Patke DS, Ahmadzadeh M, Bingaman AW, et al. Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells. Clin Immunol 2005;117:125–132.
  • Takayama T, Sekine T, Makuuchi M, et al. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet 2000;356:802–807.
  • Iwai K, Soejima K, Kudoh S, et al. Extended survival observed in adoptive activated T lymphocyte immunotherapy for advanced lung cancer: results of a multicenter historical cohort study. Cancer Immunol Immunother 2012;61:1781–1790.

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