10
Views
17
CrossRef citations to date
0
Altmetric
Original Article

The Use of a Commercially Available Immunoassay to Determine the Level of Interleukin-6 in the Serum of Patients with Myeloma

, , , &
Pages 151-155 | Received 22 Feb 1991, Accepted 03 Mar 1991, Published online: 01 Jul 2009

References

  • Dutton R. W., Falkoff R., Hirst J. A., Hoffman M., Kappler J., Kettman J. R., Lesley J. F., Van D. Is there evidence for a nonantigen specific diffusible chemical mediator from the thymus cell in the initiation of the immune response?. Progress in Immunology 1971; 1: 355–70
  • Kishimoto T., Ishizaka K. Regulation of antibody responses in vitro. VII. Enhancing soluble factors for IgG and IgE antibody response. Journal of Immunology 1973; 111: 1194–1205
  • Muraguchi A., Kishimoto T., Miki Y., Kuritani T., Kaieda T., Yoshizaki K., Yamamura Y. T cell replacing factor (TRF)-induced IgG secretion in human B blastoid cell line and demonstration of acceptors for TRF. Journal of Immunology 1981; 127: 412–6
  • Okada M., Sakaguchi N., Yoshimura N., Hara H., Shimizu K., Yoshida N., Yoshizaki K., Kishimoto S., Yamamura Y., Kishimoto T. B-cell growth factor (BCGF) and B cell differentiation factor from human T hybridomas: Two distinct kinds of BCGFs and their synergism in B cell proliferation. Journal of Experimental Medicine 1989; 157: 583–90
  • Kishimoto T. The biology of Interleukin-6. Blood 1989; 74: 1–10
  • Harada N., Kikuchi Y., Taminaga A., Takaki S., Takatsu K. BCGF II activity on activated B cells of a purified murine T cell replacing factor (TRF) from a T cell hybridoma (B151K12). Journal of Immunology 1985; 134: 3944–51
  • Kinashi T., Harada N., Severinson E., Tanabe R., Sideras P., Konishi M., Azuma C., Tominaga A., Bergstedt-Lindquist S., Takahashi M., Matsuda F., Yaoita Y., Takatsu K., Honjo T. Cloning of complementary DNA coding T-cell replacing factor and identity with B-cell growth factor II. Nature 1986; 324: 70–3
  • Bergui L., Schena M., Gaidano G., Riva M., Caligaris-Cappio F. Interleukin 3 and Interleukin 6 synergistically promote the proliferation and differentiation of malignant plasma cell precursors in multiple myeloma. Journal of Experimental Medicine 1989; 170: 613–8
  • Van Damme J. G., Opdenakker G., Simpson R. J., Rubira M. R., Cayphas S., Vink A., Billau A., Van Snick J. Identification of the human 26kD protein, interferon B2 (IFN-B2) as a B cell hybridoma/plasmacytoma growth factor induced by interleukin-1 and tumor necrosis factor. Journal of Experimental Medicine 1987; 165: 914–20
  • Asaoku H., Kawano M., Iwato K., Tanabe O., Tanaka H., Hirano T., Kishimoto T., Kuramoto A. Decrease in BSF-2/IL-6 response in advanced cases of multiple myeloma. Blood 1988; 72: 429–32
  • Kawano M., Hirano T., Matsuda T., Taga T., Horii Y., Iwato K., Asaoku H., Tang B., Tanabe O., Tanaka H., Kuramoto A., Kishimoto T. Autocrine generation and requirement of BSF-2/IL-6 for human myelomas. Nature 1988; 332: 83–4
  • Klein B., Zhang X. G., Jourdan M., Content J., Houssaiu F., Aarden L., Piechaczyck M., Bataille R. A paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 1989; 73: 517–26
  • Suematsu S., Matsuda T., Aozasa K., Akira S., Nakano N., Ohno S., Miyazaki J., Yamamura Y., Hirano T., Kishimoto T. IgG1 plasmacytosis in interleukin 6 transgenic mice. Proceedings of the National Academy of Science 1989; 86: 7547–51
  • Nijstein M. W. N., De Groot E. R., Ten Duis H. J., Klansen H. J., Aarden L. A. Serum levels of interleukin-6 and acute phase responses. Lancet 1987; i: 921
  • Hack C. E., De Groot E. R., Felt-Bersma R. J., Nuijens J. H., Strack van Schijndel R. J., Eerenberg-Belmer A. J., Thijs L. S., Aarden L. A. Increased plasma levels of interleukin 6 in sepsis. Blood 1989; 74: 1704–10
  • Deviere J., Content J., Denys C., Vandenbusche P., Schandene L., Wybran J., Dupont E. High interleukin 6 serum levels and increased production by leucocytes in alcoholic liver cirrhosis. Correlation with IgA serum levels and lymphokine production. Clinical and Experimental Immunology 1989; 77: 221–5
  • Kern P., Heimmer C. J., Van Damme J., Gruss H. J., Dietrich M. Elevated tumour necrosis factor alpha and interleukin 6 serum levels as markers for complicated Plasmodium falciparnum malaria. American Journal of Medicine 1989; 87: 139–43
  • Swaak J. Interleukin 6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus. Rheumatology International 1989; 8: 263–8
  • Shenkin A., Fraser W. D., Semies J., Winstanley F. P., McCartney A. C., Burns H. J., Van Damme J. The serum interleukin 6 response to elective surgery. Lymphokine Research 1989; 8: 123–7
  • Van Oers M. H. J., Van der Heyden A. A., Aarden L. A. Interleukin 6 (IL-6) in serum and urine of renal transplant recipients. Clinical and Experimental Immunology 1988; 71: 314–9
  • Houssaiu F. A., Bukasa K., Sindic C. J. M., Van Damme J., Van Snick J. Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system. Clinical and Experimental Immunology 1988; 71: 320–3
  • Bataille R., Jourdan M., Zhang X. G., Klein B. Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflection of disease severity in plasma cell dyscrasias. Journal of Clinical Investigation 1989; 84: 2008–11
  • Chronic-Leukaemia-Myeloma Task Force. Proposed guidelines for clinical studies. Cancer Chemotherapy Reviews 1973; 4: 145–58
  • Kikutani H., Taga T., Akira S., Kishi H., Miki Y., Saiki O., Yamamura Y., Kishimoto T. Effect of B cell differentiation factor (BCDF) on biosynthesis and secretion of immunoglobulin molecules in human B cell lines. Journal of Immunology 1985; 134: 990–5
  • Gauldie J., Richards C., Harnish D., Lansdrop P., Baumann H. Interferon B2/Bcell stimulating factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proceedings of the National Academy of Science 1987; 84: 7251–5
  • Kawano M., Tanaka H., Ishikawa H., Nobuyoshi M., Iwato K., Asaoku H., Tanabe O., Kuramato A. Interleukin-1 accelerates autocrine growth of myeloma cells through interleukin-6 in human myeloma. Blood 1989; 73: 2145–8
  • James K. Interactions between cytokines and alpha-2-macroglobulin. Immunology Today 1990; 11: 163–6
  • Brown R. D., Ioannidis R. A., Joshua D. E., Kronenberg H. Serum thymidine kinase as a marker of disease activity in patients with multiple myeloma. Australian and New Zealand Journal of Medicine 1989; 19: 226–32

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.