Frequency of RAS and p53 Mutations in Acute Promyelocytic Leukemias

References

• Bishop J. M. Molecular themes in oncogenesis. Cell 1991; 64: 235–248
   PubMed Web of Science ®Google Scholar
• Hunter T. Cooperation between oncogenes. Cell 1991; 64: 249–270
   PubMed Web of Science ®Google Scholar
• Bos J. L. The ras-gene family and human carcino-genesis. Mutation Res. 1988; 195: 255–263
   PubMed Web of Science ®Google Scholar
• Hollstein M., Sidransky D., Vogelstein B., Harris C. C. p53 mutations in human cancers. Science 1991; 253: 49–53
   PubMed Web of Science ®Google Scholar
• Marshall C. J. Tumor suppressor genes. Cell 1991; 64: 313–326
   PubMed Web of Science ®Google Scholar
• Volgestein B., Fearon E. R., Hamilton S. R., Kern S. E., Preisinger A. C., Leppert M., Nakamura Y., White R., Smits A. M., Bos J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 1988; 319: 525–532
   PubMed Web of Science ®Google Scholar
• Parada L. F., Land H., Weinberg R. A., Wolf D., Rotter V. Cooperation between gene encoding p53 tumor antigen and RAS in cellular transformation. Nature 1984; 312: 649–651
   PubMed Web of Science ®Google Scholar
• Janssen J. W. G., Steenvoorden A. C. M., Lyons J., Anger B., Bohlke J. U., Bos J. L., Seliger H., Bartram C. R. RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes. Proc. Natl. Acad. Sci. USA 1987; 84: 9228–9232
   PubMed Web of Science ®Google Scholar
• Farr C. J., Saiki R. K., Erlich H. A., McCormick F., Marshall C. J. Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oli-gonucleotide probes. Proc. Natl. Acad. Sci. USA 1988; 85: 1629–1633
   PubMed Web of Science ®Google Scholar
• Sugimoto K., Toyoshima H., Sakai R., Hagiwara K., Mi-yagawa K., Ishikawa F., Takaku F., Yazaki Y., Hirai H. Mutations of the p53 gene in human leukemia cells. II Meeting on the Molecular Basis of Human Cancer, Frederick, MDUSA, 1991; 80
   Google Scholar
• Mittelman F. Catalog of Chromosome Aberrations in Cancer, 3rd edn. Liss, New York 1988
   Google Scholar
• Longo L., Donti E., Mencarelli A., Avanzi G., Pegoraro L., Alimena G., Tabilio A., Venti G., Grignani F., Pelicci P. G. Mapping of chromosome 17 breakpoints in acute myeloid leukemias. Oncogene 1990; 5: 1557–1563
   PubMed Web of Science ®Google Scholar
• Castaigne S., Chommienne C., Daniel M. T., Ballerini P., Berger R., Fenaux P., Degos L. All transretinoic acid as a differentiation therapy for acute promyelo-cytic leukemia I. Clinical results. Blood 1990; 76: 1704–1709
   PubMed Web of Science ®Google Scholar
• Chomienne C, Ballerini P., Balitrand N., Daniel M. T., Fenaux P., Castaigne S., Degos L. All-trans re-tinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood 1990; 76: 1710–1717
   PubMed Web of Science ®Google Scholar
• Lo Coco F., Avvisati G., Diverio D., Petti M. C., Al-calay M., Pandolfi P. P., Biondi A., Rambaldi A., Mo-leti M. L., Mandelli F., Pelicci P. G. Molecular evaluation of response to all-trans retinoic acid therapy in patients with acute promyelocytic leukemia. Blood 1991; 77: 1657–1659
   PubMed Web of Science ®Google Scholar
• Borrow J., Goddard A. D., Sheer D., Solomon E. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science 1990; 249: 1577–1580
   PubMed Web of Science ®Google Scholar
• de Thé H., Chomienne C, Lanotte M., Degos L., De-jean A. The t(15;17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 1990; 347: 558–561
   PubMed Web of Science ®Google Scholar
• Longo L., Pandolfi P. P., Biondi A., Rambaldi A., Men-carelli A., Lo Coco F., Diverio D., Pegoraro L., Avanzi G., Tabilio A., Donti E., Grignani F., Pelicci P. G. Rearrangements and aberrant expression of the RARα gene in acute promyelocytic leukemias. J. Exp. Med. 1990; 172: 1571–1575
   PubMed Web of Science ®Google Scholar
• Alcalay M., Zangrilli D., Pandolfi P. P., Longo L., Men-carelli A., Giacomucci A., Rocchi M., Biondi A., Rambaldi A., Lo Coco F., Diverio D., Donti E., Grignani F., Pelicci P. G. translocation breakpoint of acute promyelocytic leukemia lies within retinoic acid receptor α locus. Proc. Natl. Acad. Sci. USA 1991; 88: 1977–1981
   PubMed Web of Science ®Google Scholar
• Pandolfi P. P., Grignani F., Alcalay M., Mencarelli A., Biondi A., Lo Coco F., Grignani F., Pelicci P. G. Structure and origin of the acute promyelocytic leukemia myl/RARα cDNA and characterization of its retinoid-binding and transactivation properties. Oncogene 1991; 6: 1285–1292
   PubMed Web of Science ®Google Scholar
• deThé H., Lavau C, Marchio A., Chomienne C., Degos L., Dejean A. The PML-RARα fusion mRNA generated by the t(15; 17) translocation in acute promyelocytic leukemia encodes a functionally altered RARα. Cell 1991; 66: 675–684
   PubMed Web of Science ®Google Scholar
• Kakizuka A., Miller W. H., Jr, Umesono K., Warrell R. P., Jr, Frankel S. R., Murty V. V. V. S., Dmitrovsky E., Evans R. M. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML. Cell 1991; 66: 663–674
   PubMed Web of Science ®Google Scholar
• Biondi A., Rambaldi A., Alcalay M., Pandolfi P. P., Lo Coco F., Diverio D., Rossi V., Mencarelli A., Longo L., Zangrilli D., Masera G., Barbui T., Mandelli F., Grignani F., Pelicci P. G. RARα gene rearrangements as a genetic marker for diagnosis and monitoring in acute promyelocytic leukemia. Blood 1991; 77: 1418–1422
   PubMed Web of Science ®Google Scholar
• Bennett J. M., Catovsky D., Daniel M. T., Flandrin G., Galton D. A. G., Gralnick H. R., Sultan C. Proposals for the classification of the acute leukemias. Br. J. Haematol. 1976; 33: 451–458
   PubMed Web of Science ®Google Scholar
• An International System for Human Cytogenetic Nomenclature. ISCN. Report of the standing committee on human cytogenetic nomenclature. Cytogenet. Cell Genet. 1978; 21: 309–404
   PubMedGoogle Scholar
• Neri A., Knowles D. M., Greco A., McCormick F., Dalla-Favera R. Analysis of ras oncogene mutations in human lymphoid malignancies. Proc. Natl. Acad. Sci. USA 1988; 85: 9268–9272
   PubMed Web of Science ®Google Scholar
• Gaidano G., Ballerini P., Gong J. Z., Inghirami G., New-comb E. W., Magrath I. T., Knowles D. M., Dalla-Favera R. p53 mutations in human lymphoid malignancies: association with Burkitt's lymphoma and chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 1991; 88: 5413–5417
   PubMed Web of Science ®Google Scholar
• McMahon G., Davis E., Wogan G. N. Characterization of Ki-RAS oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors. Proc. Natl. Acad. Sci USA 1987; 84: 4974–4978
   PubMed Web of Science ®Google Scholar
• Orita M., Iwahana H., Kanazawa H., Hayashi K., Se-kiya T. Detection of polymorphisms of human DNA by gel electrophoresis as single strand conformation polymorphisms. Proc. Natl. Acad. Sci. USA 1989; 86: 2766–2770
   PubMed Web of Science ®Google Scholar
• Orita M., Suzuki Y., Sekiya T., Hayashi K. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genom-ics 1989; 5: 874–879
   PubMed Web of Science ®Google Scholar
• Sultan C, Heilmann-Gouaultme M., Tulliez M. Relationship between blast-cell morphology and occurrence of a syndrome of disseminated intravascular coagulation. Br. J. Haematol. 1973; 24: 255–260
   PubMed Web of Science ®Google Scholar
• Pandolfi P. P., Alcalay M., Fagioli M., Zangrilli D., Mencarelli A., Diverio D., Biondi A., Lo Coco F., Rambaldi A., Grignani F., Rochette-Egly C, Gaub M. P., Chambon P., Pelicci P. G. Genomic variability and alternative splicings generate multiple PML/RARa transcripts that encode aberrant PML proteins and PML/RARa isoforms in acute promyelocytic leukaemias. EMBO J. 1992; 11: 1397–1407
   PubMed Web of Science ®Google Scholar
• Alcalay M., Zangrilli D., Fagioli M., Pandolfi P. P., Mencarelli A., Lo Coco F., Biondi A., Pelicci P. G. Expression pattern of the RARa/PML fusion gene in acute promyelocytic leukemia. Proc. Natl. Acad. Sci. 1992; 89: 4840–4844
   PubMed Web of Science ®Google Scholar
• Fagioli M., Alcalay M., Pandolfi P. P., Venturini L., Mencarelli A., Simeone A., Acampora A., Grignani F., Pelicci P. G. Identification of various PML gene isoforms and characterization of their origin and expression pattern. Oncogene 1992; 7: 1083–1091
   PubMedGoogle Scholar