Growth Requirements of Normal and Leukemic Human B Cell Progenitors

References

• Cross M., Dexter T. M. Growth factors in development, transformation and tumorigenesis. Cell 1991; 64: 271–280
   PubMed Web of Science ®Google Scholar
• Le Bien T. W. Growing human B-cell precursors in vitro: the continuing challenge. Immunol. Today 1989; 10: 296–298
   PubMedGoogle Scholar
• Dorshkind K. Regulation of hemopoiesis by bone marrow stromal cells and their products. Ann. Rev. Immunol. 1990; 8: 111–137
   PubMed Web of Science ®Google Scholar
• Whitlock C. A., Witte O. N. Long-term culture of B lymphocytes and their precursors from murine bone marrow. Proc. Natl. Acad. Sci. USA 1982; 79: 3608–3612
   PubMed Web of Science ®Google Scholar
• Touw I., Delwel R., Bolhuis R., Van Zanen G., Low-Enberg B. Common and pre-B acute leukemia cells express IL-2 receptors and in vitro colony formation is stimulated in the presence of interleukin 2. Blood 1985; 66: 556–561
   PubMed Web of Science ®Google Scholar
• Uckun F. M., Kersey J. H., Gajl-Peczalska J., Heerema N. A., Provisor A. J., Haag D., Gilchrist G., Song C. W., Arthur D. C., Roloff J., Lampkin B., Greenwood M., Dewald G., Vallera D. A. Heterogeneity of cultured leukemic lymphoid progenitor cells from B-cell precursor acute lymphoblastic leukemia patients. J. Clin. Invest. 1987; 80: 639–646
   PubMed Web of Science ®Google Scholar
• Makrynikola V., Kabral A., Bradstock K. F. Effects of recombinant human cytokines on precursor-B acute lymphoblastic leukemia cells. Exp. Hematol. 1991; 19: 674–679
   PubMed Web of Science ®Google Scholar
• Wormann B., Mehta S. R., Maizel A. L., Le Bien T. W. Low molecular weight B-cell growth factor induces proliferation of human B-cell precursor acute lymphoblastic leukemias. Blood 1987; 70: 132–138
   PubMed Web of Science ®Google Scholar
• Wormann B., Gesner T. G., Mufson R. A., Le Bien T. W. Proliferative effect of interIeukin-3 on normal and leukemic human B-cell precursors. Leukemia 1989; 3: 399–404
   PubMed Web of Science ®Google Scholar
• Eder M., Ottmann O. G., Hansen-Hagge T. E., Bartram C. R., Gillis S., Hoelzer D., Ganser A. Effects of recombinant human IL-7 on blast cell proliferation in acute lymphoblastic leukemia. Leukemia 1990; 4: 533–540
   PubMed Web of Science ®Google Scholar
• Williams G. T., Smith C. A., Spooncer E., Dexter T. M., Taylor D. R. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 1990; 343: 76–79
   PubMed Web of Science ®Google Scholar
• Nunez G., London L., Hockenbery D., Alexander M., McKearn J. P., Korsmeyer S. J. Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 1990; 144: 3602–3610
   PubMed Web of Science ®Google Scholar
• Buschle M., Campana D., Carding S. R., Richard C., Hoffbrand A. V., Brenner M. K. Interferon y inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J. Exp. Med. 1993; 177: 213–218
   PubMed Web of Science ®Google Scholar
• Manabe A., Coustan-Smith E., Behm F. G., Raimondi S. C., Campana D. Bone marrow-derived stromal cells prevent apoptotic cell death in B-lineage acute lymphoblastic leukemia. Blood 1992; 79: 2370–2377
   PubMed Web of Science ®Google Scholar
• Campana D., Coustan-Smith E., Manabe A., Buschle M., Raimondi S. C., Behm F. G., Ashmun R., Arico M., Biondi A., Pui C. H. Prolonged survival of B-lineage acute lymphoblastic leukemia cells is accompanied by overexpression of bcl-2 protein. Blood 1993; 81: 1025–31
   PubMed Web of Science ®Google Scholar
• Kincade P. W., Lee G., Pietrangeli C. E., Hayashi S. I., Gimble J. M. Cells and molecules that regulate B lymphopoiesis in bone marrow. Ann. Rev. Immunol. 1989; 7: 111–43
   PubMed Web of Science ®Google Scholar
• Wolf M. L., Buckley J. A., Goldfarb A., Law C.-L., Le Bien T. W. Development of a bone marrow culture for maintenance and growth of normal human B-cell precursors. J. Immunol. 1991; 147: 3324–30
   PubMed Web of Science ®Google Scholar
• Ryan D. H., Nuccie B. L., Abboud C. N. Inhibition of human bone marrow lymphoid progenitor colonies by antibodies to VLA integrins. J. Immunol. 1992; 149: 3759–65
   PubMed Web of Science ®Google Scholar
• Novotny J. R., Duehrsen U., Welch K., Layton J. E., Cebon J. S., Boyd A. W. Cloned stromal cell lines derived from human Whitlock/Witte-type long-term bone marrow cultures. Exp. Hematol. 1990; 18: 775–84
   PubMed Web of Science ®Google Scholar
• McGinnes K., Quesniaux V., Hitzler J., Paige C. Human B-lymphopoiesis is supported by bone marrow-derived stromal cells. Exp. Hematol. 1991; 19: 294–303
   PubMed Web of Science ®Google Scholar
• Campana D., Kumagai M., Manabe A., Murti K. G., Behm F. G., Mahmoud H., Raimondi S. C. Hy-perdiploid acute lymphoblastic leukemia (ALL): a distinct biological entity with marked propensity to programmed cell death. Blood 1993, in press
   PubMed Web of Science ®Google Scholar
• Anderson D. M., Lyman S. D., Baird A., Wignall J. M., Eisenman J., Rauch C., March C. J., Boswell H. S., Gim-Pel S D, Cosman D., Williams D. E. Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 1990; 63: 235–43
   PubMed Web of Science ®Google Scholar
• Gordon M. Y., Riley G. P., Watt S. M., Greaves M. F. Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment. Nature 1987; 326: 403–5
   PubMed Web of Science ®Google Scholar
• Gimble J. M., Pietrangeli C., Henley A., Dorheim M. A., Silver J., Namen A., Takeichi M., Goridis C., Kin-Cade P. W. Characterization of murine bone marrow and spleen-derived stromal cells: analysis of leukocyte marker and growth factor mRNA transcript levels. Blood 1989; 74: 303–11
   PubMed Web of Science ®Google Scholar
• McNiece I. K., Langley K. E., Zsebo K. M. The role of recombinant stem cell factor in early B-cell development. Synergistic interaction with IL-7. J. Immunol. 1991; 146: 3785–3790
   PubMed Web of Science ®Google Scholar
• Habenicht A. Growth factors, differentiation factors and cytokines. Springer-Verlag, Berlin, Heidelberg 1990
   Google Scholar
• Roberts R., Gallagher J., Spooncer E., Allen T. D., Bloomfield F., Dexter T. M. Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis. Nature 1988; 332: 376–8
   PubMed Web of Science ®Google Scholar
• Gordon M. Y., Riley G. P., Clarke D. Heparan sulphate is necessary for adhesive interactions between human early hemopoietic progenitor cells and the extracellular matrix of the marrow microenvironment. Leukemia 1988; 2: 804–9
   PubMed Web of Science ®Google Scholar
• Saeland S., Duvert V., Pandrau D., Caux C., Durand I., Wrighton N., Wideman J., Lee F., Banchereau J. Interleukin-7 induces the proliferation of normal human B-cell precursors. Blood 1991; 78: 2229–38
   PubMed Web of Science ®Google Scholar
• Moreau I., Duvert V., Bancherau J., Saeland S. Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells. Blood 1993; 5: 1170–78
   Google Scholar
• Namen A. E., Schmierer A. E., March C. J., Overell R. W., Park L. S., Urdal D. L., Mochizuki D. Y. B-cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors. J. Exp. Med. 1988; 167: 988–1002
   PubMed Web of Science ®Google Scholar
• Takeda S., Gillis S., Palacios R. In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B and pro-T-lymphocyte clones and fetal thymocyte clones. Proc. Natl. Acad. Sci. USA 1989; 86: 1634–41
   PubMed Web of Science ®Google Scholar
• Gimble J. M., Medina K., Hudson J., Robinson M., Kincade P. W. Modulation of lymphohematopoiesis in long-term cultures by gamma interferon: direct and indirect action on lymphoid and stromal cells. Exp. Hematol. 1993; 21: 224–230
   PubMed Web of Science ®Google Scholar
• Manabe A., Yi T., Kumagai M., Campana D. Evaluation of antileukemic drugs in stroma-supported cultures of leukemic cells. I. Cytotoxicity of interferon alpha in acute lymphoblastic leukemia. Leukemia 1993; 7, in press
   Web of Science ®Google Scholar
• Law C. L., Armitage R. J., Villablanca J. G., Le Bien T. W. Expression of interleukin-4 receptors on early human B-lineage cells. Blood 1991; 78: 703–10
   PubMed Web of Science ®Google Scholar
• Okabe M., Kunieda Y., Sugiwura T., Tanaka M., Miyagishima T., Saiki I., Minagawa T., Kurosawa M., Itaya T., Miyazaki T. Inhibitory effect of interleukin-4 on the in vitro growth of Phi-positive acute lymphoblastic leukemia cells. Blood 1991; 78: 1574–1580
   PubMed Web of Science ®Google Scholar
• Pandrau D., Saeland S., Duvert V., Durand I., Manel A. M., Zabot M T., Philippe N., Bancherau J. Interleukin 4 inhibits in vitro proliferation of leukemic and normal human B cell precursors. J. Clin. Invest. 1992; 90: 1697–1706
   PubMed Web of Science ®Google Scholar
• Manabe A., Coustan-Smith E., Kumagai M., Behm F. G., Raimondi S. C., Pui C.-H., Campana D. Interleukin-4 Induces Programmed Cell Death (Apoptosis) in Human B Cell Progenitors. Blood 1993, in press
   PubMed Web of Science ®Google Scholar
• Wyllie A. H., Kerr J. F. R., Currie A. R. Cell death: the significance of apoptosis. Int. Rev. Cytol. 1980; 68: 251–306
   PubMedGoogle Scholar
• Cohen J. J. Programmed cell death in the immune system. Adv. Immunol. 1991; 50: 55–85
   PubMed Web of Science ®Google Scholar
• Jacobsen K., Osmond D. G. Microenvironmental organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow. Eur. J. Immunol. 1990; 20: 2395–404
   PubMed Web of Science ®Google Scholar
• Campana D., Farrant J., Inamdar N., Webster A. D. B., Janossy G. Phenotypic features and proliferative activity of B-cell progenitors in X-linked agammaglobulinemia. J. Immunol. 1990; 145: 1675–80
   PubMed Web of Science ®Google Scholar
• Greaves M. F. Differentiation-linked leukemogenesis in lymphocytes. Science 1986; 234: 697–704
   PubMed Web of Science ®Google Scholar
• Campana D., Janossy G. Proliferation of normal and malignant human immature lymphoid cells. Blood 1988; 71: 1201–1210
   PubMed Web of Science ®Google Scholar
• Vaux D. L., Cory S., Adams J. M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440–42
   PubMed Web of Science ®Google Scholar
• Hockenbery D., Nunez G., Milliman C., Schreiber R. D., Korsmeyer S. J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990; 348: 334–336
   PubMed Web of Science ®Google Scholar
• Sentman C. L., Shutter J. R., Hockenbery D., Kanagawa O., Korsmeyer S. J. Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 1991; 67: 879–88
   PubMed Web of Science ®Google Scholar
• Miyashita T., Hovey L., Reed J. C. Bcl-2 oncoprotein blocks chemotherapy-induced cell death and DNA-fragmentation in a human leukemia cell line. Blood 1992; 80: 357a
   Google Scholar
• Walton M. I., Whysong D., O'Connor P. M., Hockenbery D., Korsmeyer S. J., Kohn K. W. Constitutive expression of human bcl-2 modulates nitrogen mustard and camptofhecin induced apoptosis. Cancer Res. 1993; 53: 1853–1861
   PubMed Web of Science ®Google Scholar
• Williams G. T. Programmed cell death: apoptosis and oncogenesis. Cell 1991; 65: 1097–1098
   PubMed Web of Science ®Google Scholar
• Sawyers C. L., Denny C. T., Witte O. N. Leukemia and disruption of normal hematopoiesis. Cell 1991; 64: 337–346
   PubMed Web of Science ®Google Scholar
• Tsujimoto Y., Cossman J., Jaffe E., Croce C. M. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985; 228: 1440–5
   PubMed Web of Science ®Google Scholar
• Reed J. C., Cuddy M., Slabiak T., Croce C. M., Now-Ell P. C. Oncogenic potential of bcl-2 demonstrated by gene transfer. Nature 1988; 336: 259–62
   PubMed Web of Science ®Google Scholar
• Bertoli L. F., Kubagawa H., Borzillo G. V., Burrows P. D., Schreeder M. T., Carroll A. J., Cooper M. D. Bone marrow origin of a B-cell lymphoma. Blood 1988; 72: 94–103
   PubMed Web of Science ®Google Scholar
• McDonnell T. J., Korsmeyer S. J. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature 1991; 349: 254–7
   PubMed Web of Science ®Google Scholar
• Pezzella F., Tse A. G. D., Cordell J. L., Pulford K. A. F., Gaiter K. C., Mason D. Y. Expression of the bcl-2 oncogene protein is not specific for the 14; 18 chromosomal translocation. Am. J. Pathol. 1990; 137: 225–30
   PubMed Web of Science ®Google Scholar
• Rivera G. K., Raimondi S. C., Hancock M. L., Behm F. G., Pui C. H., Abromowitch M., Mirro J., Ochs J. S., Look A. T., Williams D. L., Murphy S. B., Dahl G. V., Kalwinsky D. K., Evans W. E., Kun L. E., Simone J. V., Crist W. M. Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy. Lancet 1991; 337: 61–6
   PubMed Web of Science ®Google Scholar
• Hoelzer D. High-dose chemotherapy in adult acute lymphoblastic leukemia. Semin. Hematol. 1991; 28: 84–9
   PubMed Web of Science ®Google Scholar
• Lowenberg B., van Putten W. L. J., Touvv I. P., Delwel R., Santini V. Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia. N. Engl. J. Med. 1993; 328: 614–9
   PubMed Web of Science ®Google Scholar
• Pieters R., Loonen A. H., Huismans D. R., Broekema G. J., Dirven M. W. J., Heyenbrok M. W., Hahlen K., Veerman A. J. P. In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions. Blood 1990; 76: 2327–36
   PubMed Web of Science ®Google Scholar
• Campana D., Manabe A., Evans W. E. Stroma-supported immunocytometric assay (SIA): a novel method for testing the sensitivity of acute lymphoblastic leukemia cells to cytotoxic drugs. Leukemia 1992; 7: 482–8
   Web of Science ®Google Scholar
• Miyake K., Weissman I. L., Greenberg J. S., Kincade P. W. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J. Exp. Med. 1991; 173: 599–607
   PubMed Web of Science ®Google Scholar
• Ryan D. H., Nuccie B. L., Abboud C. N., Winslow J. M. Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B-cell precursors to cultured bone marrow adherent cells. J. Clin. Invest. 1991; 88: 995–1004
   PubMed Web of Science ®Google Scholar
• Miyake K., Medina K. L., Hayashi S. I., Ono S., Hamaoka T., Kincade P. W. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. J. Exp. Med. 1990; 171: 477–488
   PubMed Web of Science ®Google Scholar
• Sellins K. S., Cohen J. J. Gene induction by y-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol. 1987; 139: 3199–206
   PubMed Web of Science ®Google Scholar
• Darzynkiewicz Z., Bruno S., Del Bino G., Gorczyca W., Hotz M. A., Lassota P., Traganos F. Features of apoptotic cells measured by flow cytometry. Cytometry 1992; 13: 795–808
   PubMedGoogle Scholar
• Swat W., Ignatowicz L., Kisielow P. Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry. J. Immunologic. Meth. 1991; 137: 79–87
   PubMed Web of Science ®Google Scholar
• Wright D. G., Greenberg J. S. Long-term bone marrow culture. Alan R. Liss, New York 1984
   Google Scholar
• Hayashi J., Medlock E. S., Goldschneider I. A selective culture system for generating terminal deoxynucleo-tidyl transferase-positive lymphoid precursor cells in vitro. J. Exp. Med. 1984; 160: 1622–39
   PubMed Web of Science ®Google Scholar
• Schmid I., Uittenbogaart C. H., Giorgi J. V. A gentle fixation and permeabilization method for combined cell surface and intracellular staining with improved precision in DNA quantification. Cytometry 1991; 12: 279–85
   PubMedGoogle Scholar