94
Views
25
CrossRef citations to date
0
Altmetric
Original Article

Tracing the Expression of CD7 and other Antigens during T- and Myeloid-cell Differentiation in the Human Fetal Liver and Thymus

, , &
Pages 1-11 | Received 16 May 1994, Published online: 01 Jul 2009

References

  • Haynes B.F., Eisenbarth G.S., Fauci A.S. Human lymphocyte antigens: production of a monoclonal antibody that defines functional thymus-derived lymphocyte-subsets. Proc. Natl. Acad. Sci. USA 1979; 76: 5829–5833
  • Eisenbarth G.S., Haynes B.F., Shroer J.A., Fauci A.S. Production of monoclonal antibodies reacting with peripheral blood mononuclear cell surface differntiation antigens. J. Immunol. 1980; 124: 1237–1244
  • Grümayer E.R., Griesinger F., Hummell D.S., Brunning R.D., Kersey J.H. Identification of novel B-lineage cells in human fetal bone marrow that coexpress CD7. Blood 1991; 77: 64–68
  • Lanier L.L., Chang C., Spits H., Phillips J.H. Expression of cytoplasmic CD3° proteins in activated human adult killer (NK) cells and CD3°, δ, complexes in fetal NK cells. J. Immunol. 1992; 149: 1876–1880
  • Akbar A.N., Amlot P.L., Hawkins C., Newsholme W., Delaney S., Borthwick N., Janossy G. The effect of a chimeric mouse-human CD7 antibody on human T., natural killer, and lymphocyte activated killer cell activity in vitro. Transplantation 1991; 52: 325–330
  • Rabinowich H., Pricop L., Herberman R.B., Whiteside T.L. Expression and function of CD7 molecule on human natural killer cells. J. Immunol. 1994; 152: 517–526
  • Ware R.E., Scearce R.M., Dietz M.A., Starmer C.F., Palker T.J., Haynes B.F. Characterization of the surface topography and putative tertiary structure of the human CD7 molecule. J. Immunol. 1989; 143: 3632–3640
  • Haynes B.F., Metzgar R.S., Minna J.D., Bunn P.A. Phenotypic characterization of cutaneous T-cel 1 lymphoma. N. Engl. J. Med 1981; 304: 1319–1323
  • Vodinelich L., Tax W., Bai Y., Pegram S., Capel P., Greave M.F. A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL). Blood 1983; 62: 1108–1113
  • Lo Coco F., De Rossi G., Pasqualetti D., López M., Diverio D., Latagliata R., Fenu S., Mandelli F. CD7 positive acute myeloid leukemia: a subtype associated with cell immaturity. Br. J. Haematol. 1989; 73: 480–485
  • Hara J., Yumura Y.K., Tawa A., Ishihara S., Murata M., Terada N., Izumi Y., Champagne E., Takihara Y., Mak T.W., Minden M., Kawa-Ha K. Molecular analysis of acute undifferentiated leukemia: two distinct subgroups at the DNA and RN A levels. Blood 1989; 74: 1738–1746
  • Kurtzberg J., Waldman T.A., Davey M.P., Bigner S.H., More J.O., Hershfield M.S., Haynes B.F. CD7+CD4-CD8-acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells. Blood 1989; 73: 381–390
  • Yumura Y.K., Hara J., Kurahashi H., Okamura J., Koizumi S., Toyoda Y., Murayama N., Inoue M., Ishihara S., Tawa A., Nishiura T., Kaneyama Y., Okada S., Kawa H.K. Clinical significance of CD7-positive stem cell leukemia. Cancer 1991; 68: 2273–2280
  • Aruffo A., Seed B. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system. EMBO J. 1987; 6: 3313–3316
  • Schanberg L.E., Fleenor D.E., Kurtzberg J., Haynes B.F., Kaufman R.E. Isolation and characterization of the genomic human CD7 gene. Structural similarity with the murine Thy-1 gene. Proc. Natl. Acad. Sci. USA 1991; 88: 603–607
  • Osada S., Utsumi K.R., Ueda R., Akao Y., Tsuge I., Nishida K., Okada J., Matsuoka H., Takahashi T. Assignment of a gene encoding for a human T-cell antigen with a molecular weight of 40,000 daltons to chromosome 17. Cytogenet. Cell. Genet. 1988; 47: 8–10
  • Yoshikawa K., Seto M., Ueda R., Obata Y., Notake K., Yokochi T., Takahashi T. Molecular cloning of the gene coding for the human T cell differentiation antigen CD7. Immunogenetics 1991; 33: 352–360
  • Ware R.E., Hart M.K., Haynes B.F. Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced trasmembrane calcium flux. J. Immunol. 1991; 147: 2787–2794
  • Ware R.E., Haynes B.F. T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. Int. Immunol. 1992; 5: 179–187
  • Morishima Y., Kobayashi M., Yang S.Y., Collins N.H., Hoffman M.K., Dupont B. Functionally different T lymphocyte subpopulations determined by their sensitivity to complement-dependent cell lysis with the monoclonal antibody 4A. J. Immunol. 1982; 129: 1091–1098
  • Jung L. K. L., Fu S.M. Effect of tumor promoter 12-O-tetradecanoyl-phorbol 13-acetate on CD7 expression by T lineage cells. Eur. J. Immunol. 1988; 18: 711–717
  • Shimizu Y., van Seventer G.A., Ennis E., Newman W., Horgan K.J., Shaw S. Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion. J. Exp. Med 1992; 175: 577–582
  • Sandrin M.S., Vaughn H.A., Lovering K.E., Curnow K., Deacon N.J., McKenzie I. N. C. Characterization of the gene coding for the human lymphocyte surface antigen HuLy-m2 (CD7). Leukocyte Typing III. Oxford University press, Oxford 1987; 216
  • Carrera A.C., Rincón M., Sánchez-Madrid F., López-Botet M., de Landazuri M.O. Triggering of comitogenic signals in T cell proliferation by anti-LFA (CD 18, CD 11 a), LFA-3 and CD7 monoclonal antibodies. J. Immunol. 1988; 141: 1919–1924
  • Ledbetter J.A., June C.H., Grosmaire L.S., Rabinovich P.S. Crosslinking of surface antigens causes mobilization of intracellular ionized calcium. Proc. Natl. Acad. Sci. USA 1987; 84: 1384–1388
  • Carrel S., Salvi S., Rafti F., Favrot M., Rapin C., Selaky R.P. Direct involvement of CD7 (gp40) in the activation of TcR γ/δ+ T cells. Eur. J. Immunol. 1991; 21: 1195–1200
  • Jung L. K. L., Roy A.K., Chakkalath H.P. CD7 augments T cell proliferation via the interleukin-2 autocrine pathway. Cell. Immunol. 1992; 141: 189–199
  • Lazarovits A.I., Karsh J. A monoclonal antibody 7G5 (CD7), induces modulation of Tp40 and inhibits proliferation in the allogeneic and autologous mixed lymphocyte reactions. Transplant. Proc. 1988; 20: 1253–1257
  • Costantinides Y., Kingsley G., Pitzalis C., Panayi G.S. Inhibition of lumphocyte proliferation by a monoclonal antibody (RFT2) against CD7. Clin. Exp. Immunol. 1991; 85: 164–167
  • Lazarovits A.I., Karsh J. Modulation of CD7 is associated with inhibition of T cell proliferation in response to tetanus toxoid and phytohemaglutinin. Transplant. Proc 1989; 21: 3325–3327
  • Chabannon C., Wood P., Torok-Storb B. Expression of CD7 on normal human myeloid progenitors. J. Immunol. 1992; 149: 2110–2113
  • Lobach D.F., Haynes B.F. Ontogeny of the human thymus during fetal development. J. Clin. Immunol. 1987; 7: 81–97
  • Lobach D.F., Hensley L.L., Ho W., Aynes H. B. F. Human T-cell antigen expression during early stages of fetal thymic maturation. J. Immunol. 1985; 1351: 1752–1759
  • Haynes B.F., Martin M.E., Kay H.H., Kurtzberg J. Early events in human T cell ontogeny: Phenotypic characterization and immunohistological localization of T-cell precursors in early human fetal tissues. J. Exp. Med. 1988; 168: 1061–1080
  • Campana D., Janossy G., Coustan-Smith E., Amlot P.L., Tian W.-T., Ip S., Wong L. The expression of T cell receptor-associated proteins during T cell ontogeny in man. J. Immunol. 1989; 142: 57–66
  • Phillips J.H., Hori T., Nagler A., Bhat N., Spits H., Lanier L.L. Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon, delta proteins. J. Exp. Med. 1992; 175: 1055–66
  • Jung L. J. L., Fu S.M., Hara T., Kapoor N., Good R.A. Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency. J. Clin. Invest. 1986; 77: 940–946
  • Terstappen L.W., Huang S., Picker L.J. How cytometric assessment of human T-cell differentiation in thymus and bone marrow. Blood 1992; 79: 666–677
  • Mossalayi M.D., Lecron J.C., Goube de Laforest P., Janossy G., Debre P., Tanzer J. Characterization of prothymocytes with cloning capacity in human bone marrow. Blood 1988; 71: 1281
  • Bertho J.M., Mossalayi M.D., Dalloul A.H., Mouterde G., Debre P. Isolation of an early T-cell precursor (CFU-T) from human bone marrow. Blood 1990; 75: 1064–1068
  • Tjønnfjord G.E., Veiby O.P., Steen R., Egeland T. T lymphocyte differentiation in vitro from adult human prethymic CD34+ bone marrow cells. J. Exp. Med. 1993; 177: 1531–1539
  • Yeoman H., Gress R.E., Bare C.V., Leary A.G., Boyse E.A., Bard J., Schultz L., Harris D.T., De Luca D. Human bone marrow and umbilical cord blood cells generate CD4+ and CD8+ single-positive T cells in murine fetal thymus organ culture. Proc. Natl. Acad. Sci. USA 1993; 90: 10778–10782
  • Toribio M.L., Alonso J.M., Barcena A., Gutiérrez J.C., de la Hera A., Marcos M. A. R., Márquez C., Martínez A.C. Human T-cell precursors: involvement of the IL-2 pathway in the generation of mature T cells. Immunol. Rev. 1988; 104: 55–79
  • Haynes B.F., Denning S.M., Singer K.H., Kurtzberg J. Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development. Immunol. Today 1989; 10: 87–91
  • Hori T., Spits H. Clonal analysis of human CD4-CD8-CD3-thymocytes highly purified from postnatal thymus. J. Immunol. 1991; 146: 2116–2121
  • Barcena A., Muench M.O., Galy A. H. M., Cupp J., Roncarolo M.G., Phillips J.H., Spits H. Phenotypic and functional analysts of T-cell precursors in the human fetal liver and thymus. CD7 expression in the early stages of T-and myeloid-cell development. Blood 1993; 82: 3401–3414
  • De la Hera A., Toribio M.L., Martinez A.C. Delineation of human thymocytes with or without functional potential by CDI-specific antibodies. Int. Immunol. 1989; 1: 496–502
  • Galy A., Verma S., Bárcena A., Spits H. Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by CD34. Delineation of early events in human thymic development. J. Exp. Med 1993; 178: 391–401
  • Griffin J.D., Linch D., Sabbath K., Larcom P., Schlossman S.F. A monoclonal antibody reactive with normal and leukemic myeloid progenitor cells. Leuk. Res. 1984; 8: 521–534
  • Le Bien T.W., McCormack R.T. The common acute lymphoblastic leukemia antigen (CD 10)-emancipation from a functional enigma. Blood 1989; 73: 625–635
  • Yssel H., De Vries J.E., Koken M., van Blitterswijk W., Spits H. Serum-free medium for the generation and the propagation of functional human cytotoxic and helper T cell clones. J. Immunol. Meth. 1984; 72: 219–227
  • Patel D.D., Haynes B.F. Cell adhesion molecules involved in intrathymic T cell development. Seminars in Immunol. 1993; 5: 283–292
  • Sánchez M.J., Gutierrez-Ramos J.C., Fernandez E., Leonardo E., Lozano J., Martínez A.C., Toribio M.L. Putative prethymic T cell precursor within the early embryonic liver: a molecular and functional analysis. J. Exp. Med. 1993; 177: 19–33
  • Galy A. H. M., Spits H. IL-1, IL-4 and IFN-γ differentially regulate cytokine production and cell surface molecule expression in culture thymic epithelial cells. J. Immunol. 1991; 147: 3823–3830
  • Galy A. H. M., Spits H. CD40 is functionally expressed on human thymic epithelial cell. J. Immunol. 1992; 149: 775–782
  • Galy A. H. M., de Waal Malefyt R., Bárcena A., Mohan-Peterson S., Spits H. Untransfected and SV40-transfected fetal and postnatal human stromal cells. Analysis of phenotype, cytokine gene expression and cytokine production. Thymus 1993; 22: 13–33
  • Fisher A.G., Larsson L., Goff L.K., Restall D.E., Happerfield L., Merkenschlager M. Human thymocyte development in mouse organ cultures. Int. Immunol. 1990; 2: 571–578
  • Jenkinson E.J., Franchi L.L., Kingston R., Owen J. J. T. Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: Application in the production of chimeric thymus rudiments. Eur. J. Immunol. 1982; 12: 583–587
  • Muench M.O., Cupp J., Polakoff J., Roncarolo M.G. Characterization of CD33, CD38 and HLA-DR expression on human fetal liver progenitors with a high proliferative potential. Blood 1994; 83: 3170–3181
  • Terstappen L. W. M. M., Huang S., Safford M., Lansdorp P.M., Loken M.R. Sequential generation of hematopoietic colonies derived from single nonlineage-committed CD34+CD38-progenitor cells. Blood 1991; 77: 1218–1227
  • Huang S., Terstappen L. W. M. M. Lymphoid and myeloid differentiation of single human CD34+HLADR+, CD38-hematopoietic stem cells. Blood 1994; 83: 1515–1526
  • Cross A.H., Goorha R.M., Nuss R., Behm F.G., Murphy S.B., Kalwinsky D.K., Raimondi S., Kitchingman G.R., Mirro J., Jr. Acute myeloid leukemia with T-lymphoid features: A distinct biological and clinical entity. Blood 1988; 72: 579–587
  • Buccheri V., Matutes E., Dyer M. J. S., Catovsky D. Lineage commitment in biphenotypic acute leukemia. Leukemia 1993; 7: 919–927
  • Bárcena A., Galy A. H. M., Punnonen J., Muench M.O., Schols D., Roncarolo M.-G., De Vries J.E. Lymphoid and myeloid differentiation of fetal liver CD34+lineage-cells in human thymic organ culture. J. Exp. Med. 1994; 180: 123–132
  • Janossy G., Bofill M., Poulter L. W. E. R., Burford G.D., Navarrete C., Ziegler A., Kelemen E. Separate ontogeny of two macrophage-like accesory cell populations in the human fetus. J. Immunol. 1986; 136: 4354–4361
  • Ruco L.P., Rosati S., Monardo F., Pescarmona E., Rendina E.A., Baroni C.D. Macrophages and interdigitating reticulum cells in normal thymus and in thymoma: an immunohistological study. Histopathology 1989; 14: 37–45
  • Mingari M.C., Poggi A., Biassoni R., Bellomo R., Ciccone E., Pella N., Morelli L., Verdiani S., Moretta A., Moretta L. In vitro proliferation and cloning of CD3-CDI6+ cells from human thymocyte precursors. J. Exp. Med. 1991; 174: 21–26
  • Isaacson P.G., Norton A.J., Addis B.J. The human thymus contains a novel population of B lymphocytes. Lancet 1987; 2: 1488–1494
  • Spangrude G.J., Scollay R. Differentiation of hematopoietic cells in irradiated mouse thymic lobes: kinetics and phenotype of the progeny. J. Immunol. 1990; 145: 3661–3668
  • Kurtzberg J., Denning S.M., Nycum L.M., Singer K.H., Haynes B.F. Immature human thymocytes can be driven to differentiate into nonlymphoid lineages by cytokines from thymic epithelial cells. Proc. Natl. Acad. Sci. USA 1989; 86: 7575–7579
  • Issaad C., Croisille L., Katz A., Vainchenker W., Coulombel L. A murine stromal cell line allows the proliferation of very primitive human CD34++/CD38-progenitor cells in long-term cultures and semisolid assays. Blood 1993; 81: 2916–2924

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.