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Original Article

Patterns of Drug Resistance Parameters in Adult Leukemia

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Pages 101-109 | Received 08 Jun 1994, Published online: 01 Jul 2009

References

  • Vendrik C. P. J., Bergers J.J., Dejong W.H., Steerenberg P.A. Resistance to Cytostatic Drugs at the Cellular Level. Cancer Chemother. Pharmacol. 1992; 29(6): 413–429
  • Juliano R.L., Ling V.A. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta. 1976; 455: 152–162
  • Ling V. P-Glycoprotein and Resistance to Anticancer Drugs (Reprinted from Accomplishments in Cancer Research, Pg. 79, 1991). Cancer 1991; 69(10)2603–2609
  • Roninson I.B. The Role of the MDR1 (P-Glycoprotein) Gene in Multidrug Resistance in Vitro and in Vivo. Biochem. Pharmacol. 1992; 43(1)95–102
  • Koberda J., Hellmann A. Glutathione S-Transferase Activity of Leukemic Cells as a Prognostic Factor for Response to Chemotherapy in Acute Leukemias. Med. Oncol & Tumor Pharmacother. 1991; 8(1)35–38
  • Tidefelt U., Elmhornrosenborg A., Paul C., Hao X.Y., Mannervik B., Eriksson L.C. Expression of Glutathione Transferase-pi as a Predictor for Treatment Results at Different Stages of Acute Nonlymphoblastic Leukemia. Cancer Res. 1992; 52(12): 3281–3285
  • Suzukake K., Petro B., Vistica D.T. Reduction in glutathione content of L-PAM resistent L1210 cells confers drug sensitivity. Biochem. Pharmacol. 1982; 31: 121–124
  • Crook T.R., Sonhami R.L., Whyman G.D., McLean A. E. M. Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide. Cancer Res. 1986; 46: 5035–5038
  • Kramer R.A., Zakher J., Kim G. Role of Glutathione Redox Cycle in Acquired and de Novo Multidrug Resistance. Science 1988; 241: 694–697
  • Arrick B.A., Nathan C.F. Glutathione Metabolism as a Determinant of Therapeutic Efficacy: AReview. Cancer Res. 1984; 44: 4224–4232
  • Black S.M., Wolf C.R. The role of glutathione-de-pendent enzymes in drug resistance. Pharmacol Ther. 1991; 51: 139–154
  • Redmond S. M. S., Joncourt F., Buser K., Ziemiecki A., Altermatt H.J., Fey M., Margison G., Cerny T. Assessment of P-glycoprotein, glutathione-based detoxifying enzymes and 06-alky 1-guanine-DNA-alkyltransferase as potential indicators of constitutive drug resistance in human colorectal tumors. Cancer Res. 1991; 51: 2092–2097
  • Carmichael J., Forrester L.M., Lewis A.D., Hayes J.D., Hayes P.C., Wolf C.R. Glutathione-S-transferase isoenzymes and glutathione peroxidase activity in normal and tumour samples from human lung. Carcinogenesis 1988; 9(9)1617–1621
  • Di Ilio C., Del Boccio G., Casaccia R., Aceto A., Di Giacomo F., Federici G. Selenium level and glutathione-dependent enzyme activities in normal and neoplastic human lung tissues. Carcinogenesis 1987; 8(2)281–284
  • Howie A.F., Forrester L.M., Glancey M.J., Schlager J.J., Powis G., Beckett G.J., Hayes J.D., Wolf C.R. Glutathione-S-transferase and glutathione peroxidase expression in normal and tumour human tissues. Carcinogenesis 1990; 11(3): 451–458
  • Pegg A.E., Byers T.L. Repair of DNA Containing 06-Alkylguanine. FASEBJ. 1992; 6(6)2302–2310
  • D'Incalci M., Citti L., Taverna P., Catapano C.V. Importance of the DNA repair enzyme 06-alkylguanine alkyl transferase (AT) in cancer chemotherapy. Cancer Treat. Rev. 1988; 15: 279–292
  • Fujio C., Chang H.R., Tsujimura T., Ishizaki K., Kitamura H., Ikenaga M. Hypersensitivity of human tumor xenografts lacking 06-Alkylguanine-DNA-alkyltransferase to the anti-tumor agent (1-(4-amino-2-methyl-5-pyrimidiny 1)methyl-3-(2-chloro-ethyl)-3-nitrosourea. Carcinogenesis 1989; 10: 351–356
  • Trey J.E., Gerson S.L. The role of 06-Alkylguanine-DNA Alkyltransferase in limiting nitrosourea-induced sister chromatid exchanges in proliferating human lymphocytes. Cancer Res. 1989; 49: 1899–1903
  • Tagliabue G., Citti L., Massazza G., Damia G., Giavazzi R., Dincalci M. Tumour of Levels of 06-Alkylguanine-DNA-Alkyltransferase and Sensitivity to BCNU of Human Xenografts. Anticancer Res. 1992; 12(6B)2123–2126
  • Gerson S.L., Berger N.A., Arce C., Petzoid S.J., Willson J. K. V. Modulation of Nitrosourea Resistance in Human Colon Cancer by 06-Methylguanine. Biochem. Pharmacol. 1992; 43(5)1101–1107
  • Joncourt F., Oberli A., Redmond S. M. S., Fey M.F., Tobler A., Margison G.P., Gratwohl A., Buser K., Cerny T. Cytostatic Drug Resistance-Parallel Assessment of Glutathione-Based Detoxifying Enzymes, 06-Alkylguanine-DNA-Alkyltransferase and P-Glycoprotein in Adult Patients with Leukaemia. Br. J. Haematol. 1993; 85(1)103–111
  • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Annals Biochem. 1969; 27: 502–522
  • Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-Transferase: the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974; 249(22)7130–7139
  • Gunzler W.A., Kremers H., Flohé L. An Improved Coupled Test Procedure for Glutathione Peroxidase (EC 1.11.1.9.) in Blood. Z. Klin. Chem. Klin. Biochem. 1974; 12: 4444–4448
  • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Annals Biochem. 1976; 72: 248–254
  • Morten J. E. N., Margison G.P. Increased 06-Alkylguanine Alkyltransferase Activity in Chinese Hamster V79 Cells following Selection with Chloroethylating Agents. Carcinogenesis 1988; 9(1)45–49
  • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680
  • Ito Y., Tanimoto M., Kumazawa T., Okumura N., Morihima Y., Ohno R., Saito H. Increased P-glycoprotein expression and multidrug-resistant gene (mdr1) amplification are infrequently found in fresh acute leukemia cells. Cancer 1989; 63: 1534–1538
  • Chitnis M., Hegde U., Chavan S., Juvekar A., Advani S. Expression of the Multidrug Transporter P-Glycoprotein and In vitro Chemosensitivity-Correlation with In vivo Response to Chemotherapy in Acute Myeloid Leukemia. Select. Cancer Ther. 1991; 7(4)165–173
  • Musto P., Melillo L., Lombardi G., Matera R., Di Giorgio G., Carotenuto M. High risk of early resistant relapse for leukaemic patients with presence of multidrug resistance associated P-glycoprotein positive cells in complete remission. Br. J. Haematol. 1991; 77: 50–53
  • Pirker R., Wallner J., Geissler K., Linkesch W., Haas O.A., Bettelheim P., Hopfner M., Scherrer R., Valent P., Havelec L. Mdr1 gene expression and treatment outcome in acute myeloid leukemia. J. Natl. Cancer Inst. 1991; 83(10)708–712
  • Marie J.P., Zittoun R., Sikic B.I. Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitive. Blood 1991; 78(3)586–592
  • Gruber A., Vitols S., Norgren S., Arestrom I., Peterson C., Bjorkholm M., Reizenstein P., Luthman H. Quantitative Determination of mdrl Gene Expression in Leukaemic Cells from Patients with Acute Leukaemia. Br. J. Cancer. 1992; 66(2)266–272
  • Cumber P.M., Jacobs A., Hoy T. J. F., Whittaker J.A., Tsuruo T., Padua R.A. Expression of the multiple drug resistance gene (mdr-1) and epitope masking in chronic lymphatic leukaemia. Br. J. Haematol. 1990; 76: 226–230
  • Zhou D.C., Marie J.P., Suberville A.M., Zittoun R. Relevance of mdr1 Gene Expression in Acute Myeloid Leukemia and Comparison of Different Diagnostic Methods. Leukemia 1992; 6(9)879–885
  • Gekeler V., Frese G., Noller A., Handgretinger R., Wilisch A., Schmidt H., Muller C.P., Dopfer R., Klingebiel T., Diddens H. Mdr1/P-Glycoprotein, Topoisomerase, and Glutathione-S-Transferase-pi Gene Expression in Primary and Relapsed State Adult and Childhood Leukaemias. Br. J. Cancer 1992; 66(3)507–517
  • Willman C.L., Kopecky K.J., Weick J., Applebaum F., Grever M.R., Head D.R., Elias L., Balcerzak S.P., Mills G.M., Hynes H.E. Biologic parameters that predict treatment response in de novo acute myeloid leukaemia (AML): CD34 but not multidrug resistance (mdr) gene expression is associated with a decreased complete remission (CR) rate and CD34+ patients more frequently achieve CR with high dose cytosine arabinoside. Proc. ASCO 1992; 11: A262
  • Ball E.D., Lawrence D., Malnar M., Ciminelli N., Mayer N., Wurster-Hill D., Davey F.R., Bloomfield C.D. Correlation of CD34 and multi-drug resistance P170 with FAB and cytogenetics but not prognosis in acute myeloid leukemia (AML). Blood 1990; 76: 252a
  • Sargent J., Elgie A., Talor C., Faulkner-Pulsford J. Resistance patterns of anthracycline analogues in acute myeloid leukemia (AML) using the MTT assay. Drug resistance in leukemia and lymphoma, G. J. L. Kaspers, R. Pieters, P.R. Twentyman, L.M. Weisenthal, A. J. P. Veerman. Harwood academic publishers. 1993; 285–297
  • Ubezio P., Limonta M., D'Incalci M., Damia G., Masera G., Giudici G., Wolverton J.S., Beck W.T. Failure to detect the P-Glycoprotein Multidrug-Resistant phenotype in cases of resistant childhood acute lymphocytic leukemia. Eur. J. Cancer Clin. Oncol. 1990; 25(12)1895–1899
  • Campos L., Guyotat D., Archimbaud E., Calmard-Oriol P., Tsuruo T., Troncy J., Treille D., Fiere D. Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis. Blood 1992; 79(2)473–476
  • Sato H., Preisler H., Day R., Razo A., Larson R., Browman G., Goldberg J., Vogler R., Grunwald H., Gottlieb A. Mdr1 transcript levels as an indication of resistant disease in acute myelogenous leukemia. Br. J. Haematol. 1990; 75: 340–345
  • Michieli M., Damiani D., Geromin A., Michelutti A., Fanin R., Raspadori D., Russo D., Visani G., Dinota A., Pileri S. Overexpression of Multidrug Resistance-Associated pi 70-Glycoprotein in Acute Non-Lymphocytic Leukemia. Eur. J. Haematol. 1992; 48(2)87–92
  • Kuwazuru Y., Yoshimura A., Hanada S., Utsunomiya A., Makino T., Ishibashi K., Kodama M., Iwahashi M., Arima T., Akiyama S. Expression of the multidrug transporter P-glycoprotein, in acute leukemia cells and correlation to clinical drug resistance. Cancer 1990; 66(5)868–873
  • Holmes J.A., West R.R. The effect of MDR-1 geneex-pression on outcome in acute myeloblastic leukaemia. Br. J. Cancer 1994; 69(2)382–384
  • Farber C.M., Kanganis D.N., Liebes L.F., Silber R. Antioxidant enzymes in lymphocytes from normal subjects and patients with chronic lymphocytic leukemia: Increased glutathione peroxidase activity in CLL B lymphocytes. Br. J. Haematol. 1989; 72: 32–35
  • Robson C.N., Lewis A.D., Wolf C.R., Hayes J.D., Hall A., Proctor S.J., Harris A.L., Hickson I.D. Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity. Cancer Res. 1987; 47: 6022–6027
  • Lewis A.D., Hickson I.D., Robson C.N., Harris A.L., Hayes J.D., Griffiths S.A., Manson M.M., Hall A.E., Moss J.E., Wolf C.R. Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards. PNAS USA 1988; 85: 8511–8515
  • Ozols R.F., Louie K.G., Plowman J., Behrens B.C., Fine R.L., Dykes D., Hamilton T.C. Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione. Biochem. Pharmacol. 1987; 36: 147–153
  • Puchalski R.B., Fahl W.E. Expression of recombinant glutathione-S-transferase it, Ya, or Ybl confers resistance to alkylating agents. Med. Sci. 1990; 87: 2443–2447
  • Holmes J., Wareing C., Jacobs A., Hayes J.D., Padua R.A., Wolf C.R. Glutathione S-transferase pi expression in leukaemia: a comparative analysis with mdr-1 data. Br. J. Cancer 1990; 62: 209–212
  • Pegg A.E. Mammalian 06-alkylguanine-DNA alkyltrans-ferase: regulation and importance in response to alkylating and therapeutic agents. Cancer Res. 1990; 50: 6119–6129
  • Scudiero D.A., Meyer S.A., Clatterbuck B.E., Mattern M.R., Ziolkowski C. H. J., Day R.S. Sensitivity of human cell strains having different abilities to repair O6-methylguanine in DNA to inactivation by alkylating agent including chloroethylnitrosourea. Cancer Res. 1984; 44: 2467–2474
  • Gerson S.L., Trey J.E., Miller K., Berger N.A. Comparison of O6-Alkylguanine-DNA Alkyltransferase Activity based on Cellular DNA Content in Human, Rat and Mouse Tissues. Carcinogenesis 1986; 7(5)745–749
  • Buser K., Joncourt F., Redmond S. M. S., Altermatt H.J., Rossier J., Hanggi W., Cerny T. Drug resistance parameters in patients with breast and ovarian cancer. Eur. J. Cancer 1991; 27(Suppl, 2)210
  • Adamson P.C., Poplack D.G. Pharmacologic factors involved in the response to chemotherapy: apparent versus intrinsic drug resistance. Drug resistance in Leukemia and Lymphoma. The Clinical Value of Laboratory Studies, G. J. L. Kapsers, R. Pieters, P.R. Twentyman, L.M. Weisenthal, A. J. P. Veerman. Harwood Academic Publishers. 1993; 33–39
  • Raderer M., Scheithauer W. Clinical trials of agents that reverse multidrug resistance-A literature review. Cancer 1993; 72(12)3553–3563

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