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Original Article

Effects of BCR-ABL Antisense Oligonucleotides (AS-ODN) on Human Chronic Myeloid Leukemic Cells: AS-ODN as Effective Purging Agents

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Pages 67-76 | Received 02 Feb 1995, Published online: 01 Jul 2009

References

  • Nowell P. L., Hungerford D. A. A minute chromosome in human chronic granulocytic leukemia. Science 1960; 132: 1497
  • Groffen J., Stephenson J. R., Heisterkamp N., De Klein A., Bartran C. R., Grosveld G. Philadelphia chromosome breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93
  • Ben-Neriah Y., Daley G. Q., Mes-Masson A. M., Witte O. N., Baltimore D. The chronic myelogenous leukemia-specific p210 protein is the product of the bcr-abl hybrid gene. Science 1986; 233: 212
  • Mills K. I. Relationship between the location of the breakpoint within MBCR and clinical parameters. Leuk. and Lymph. 1993; 11, (Suppl 1), 73–79
  • McLaughlin J., Chianese E., Witte O. In vitro transformation of immature hematopoietic cells by the p210 bcrlabl oncogene product of the Philadelphia chromosome. Proc. Natl. Acad. Sci. USA 1987; 84: 6558
  • Daley G. Q., Van Effen R. A., Baltimore D. Induction of chronic myelogenous leukemia by the p210 bcrlabl gene of the Philadelphia chromosome. Science 1990; 247: 824
  • Heisterkamp N., Stam K., Groffen J., De Klein A., Grosveld G. Structural organization of bcr gene and its role in the ph translocation. Nature 1985; 315: 758
  • Haas O. A., Argyrious-Tirita A., Lion T. Parental origin of chromosome involved in the t(9;22). Nature 1992; 359: 414–16
  • Simonsson B., Oberg G., Killander A., Bjoreman M., Borkholm M., Gahrton G., Hast R., Turesson I., Uden A. M., Malm C. Intensive treatment in order to minimize the ph-positive clone in chronic myelogenic leukemia. Stem. Cells 1993; 11, Suppl 3, 73–6
  • Morecki S., Revel-Vike S., Nabet C., Pick M., Ackerstein A., Nagler A., Naparstek E., Ben-Shahar M., Slavin S. Immunological evaluation of patients with hematological malignancies receiving ambulatory cytokine-mediated immunotherapy with recombinant human interferon-alpha 2a and interleukin-2. Cancer-Immunol-Immunother. 1992; 35: 401–11
  • Calabretta B., Sims R. B., Valtieri M., Caracciolo D., Szczlik C., Venturelli D., Ratajezak M., Beran M., Gewirtz A. M. Normal and hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging. Proc. Natl. Acad. Sci. USA 1991; 15: 2351–5
  • Szczylik C., Skorski T., Nicolaides N. C., Manzella L., Malaguarnera L., Venturelli D., Gewirtz A. M., Calabretta B. Selective inhibition of leukemia cell proliferation by bcrlabl antisense oligodeoxynucleotides. Science 1991; 253: 562
  • Marie J. P., Zittoun R., Thevnin D., Mathieu M., Viguie F. In vitro culture of clonogenic leukemic cells in acute myeloid leukemia: growth pattern and drug sensitivity. Br. J. Haematol. 1983; 55: 427–37
  • Korbling M., Dorken B., Ho A. D., Pezzutto A., Hunstein W., Fliedner T. M. Autologous transplantation of blood derived hemopoietic stem cells after myeloablation therapy in a patient with Burkitt's lymphoma. Blood 1986; 67: 529–32
  • Haas R., Ho A. D., Bredthauer U., Cayeux S., Egerer G., Knauf W., Hunstein W. Successful autologous transplantation of blood stem cells mobilized with recombinant human granulocytic-macrophage colony-stimulating factor. Exp. Hematol. 1990; 18: 94–98
  • Chomcynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162: 156–59
  • Lazaridou A., Chase A., Melo J., Garicochea B., Diamond J., Goldman J. Lack of reciprocal translocation in BCR-ABL positive ph negative chronic myeloid leukemia. Leukemia 1994; 8: 454–7
  • Chen Z., Morgan R., Berger C. S., Pearce B. L., Stone J. F., Sandberg A. A. Identification of masked and variant ph (complex type) translocation in CKL and classic ph in AML and ALL by fluorescence in situ hybridization with the use of bcr-abl cosmid probes. Cancer Genet. Cytogenet. 1993; 70: 103–7
  • Barbour S. E., Bennis E. A. Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P38D1 cells. J. Biol. Chem. 1993; 268: 21875–82
  • Murray N. R., Baumgardner G. P., Burns D. J., Fields A. P. Protein kinase C isotype in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. J. Biol. Chem. 1993; 268: 15847–53
  • Boizian C., Thuoung N. T., Toulme J. J. Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides. Proc. Natl. Acad. Sci. USA 1992; 89: 768–72
  • Perlaky L., Smetana K., Busch R. K., Saijo Y., Busch H. Nucleolar and nuclear aberration in human lox tumor cells following treatment with p120 antisense oligonucleotide ISIS-3466. Cancer Lett. 1993; 74: 125–35
  • Ulla L., Diaz-Nido J., Avila J. Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. EMBO-J. 1993; 12: 1633–40
  • Whitessel L., Rosolen A., Neckers L. M. In vivo modulation of N-mye expression by continuous perfusion with an antisense oligonucleotide. Antisense Res. Dev. 1993; 1: 343–50
  • Skorski T., Szozylik C., Malaguarnera L., Calabretta B. Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligonucleotides. Folia. Histochem. Cytobiol. 1991; 29: 85–9
  • Gewirtz A. M. Potential therapeutic application of antisense oligonucleotides in the treatment of chronic myelogenous leukemia. Leuk. and Lymph. 1993; 11, Suppl 1:131–137
  • Ratjczak M. Z., Kant J. A., Luger S. M., Huiya N., Zhang J., Zon G., Gewirtz A. M. In vivo treatment of human leukemia in a scid model with c-myb antisense oligonucleotides. Proc. Natl. Acad. Sci. USA 1992; 89: 11823–11827
  • Skorski T., Nieborowska-Skorska M., Nicolaides N. C., Szczylik C., Iversen P., Iozzo R. V., Zon G., Calabretta B. Suppression of Philadelphia1 leukemia cell growth in mice by bcr-abl antisense oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA 1994; 91: 4504–4508
  • Bagar R. C., Kyle E. L., Neckers L. M. Electroporation of lymphoma cells with c-myc antisense oligonucleotides. A model for bone marrow purging. Abstract. Proc. Am. Assoc. Canc. Res. 1994; 35: 1833
  • Cross N. C., Feng L., Bungey J., Goldman J. M. Minimal residual disease after bone marrow transplant for chronic myeloid leukemia detected by the polymerase chain reaction. Leuk. and Lymph. 1993; 11, Suppl 1, 39–43
  • Arcess W., Iori A. P., Di-Nucci G., Martinez-Rolon J., Pinto R. M., Mandelli F. What does one do for the CML patient in relapse after allogeneic bone marrow transplantation?. Leuk. and Lymph. 1993; 11, Suppl 1, 213–9
  • Mughal T., Hoyle C., Goldman J. M. Autografting for patients with chronic myeloid leukemia—the Hammersmith experience. Stem. Cells 1993; 11, Suppl 3, 20 et seq
  • Simonsson B., Oberg G., Killander A., Bjoreman M., Borkholm M., Gahrton G., Hast R., Turesson I., Uden A. M., Malm C. Intensive treatment in order to minimize the ph- positive clone in chronic myelogenic leukemia. Stem. Cells 1993; 11, Suppl 3, 73 et seq
  • Crooke R. M., Hoke G. D., Shoemaker J. E. In vitro toxicological evaluation of ISIS-1082, a phosphorothioate oligonucleotide inhibitor of herpes simplex virus. Antimicrob. Agents Chemo. 1992; 36, 527:532

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