HRX Gene Rearrangement in Secondary Acute Lymphoblastic Leukemia

References

• Sait S. N., Raza A., Sandberg A. A. A t(1;11) in acute nonlymphocytic leukemia FAB type M4. Cancer Genet. Cytogenet. 1987; 24: 181–183
   PubMed Web of Science ®Google Scholar
• Feder M., Finan J., Besa E., Nowell P. A 2p;11q chromosome translocation in dysmyelopoietic preleukemia. Cancer Genet. Cytogenet. 1985; 15: 143–150
   PubMed Web of Science ®Google Scholar
• Derre J., Cherif D., Le Coniat M., Julier C., Berger R. In situ hybridization ascertains the presence of a translocation 1(2;11) in an acute monocytic leukemia. Genes Chromosomes Cancer 1990; 32: 341–344
   Web of Science ®Google Scholar
• Abe R., Ryan D., Cecalpo A., Cohen H., Sandberg A. A. Cytogenetic findings in congenital leukemia: case report and review of the literature. Cancer Genet. Cytogenet. 1983; 9: 139–144
   PubMed Web of Science ®Google Scholar
• Hagemeijer A., Hählen K., Sizoo W., Abels J. Translocation (9;11)(p21;q23) in three cases of acute monoblastic leukemia. Cancer Genet. Cytogenet. 1982; 5: 95–105
   PubMed Web of Science ®Google Scholar
• Kaneko Y., Maseki N., Takasaki N., Sakurai M., Hayashi Y., Nakazawa S., Mori T., Sakurai M., Takeda T., Shikano T., Hiyoshi Y. Clinical and hematologic characteristics in acute leukemia with 11q23 translocation. Blood 1986; 67: 484–491
   PubMed Web of Science ®Google Scholar
• Raimondi S. C., Peiper S. C., Kitchingman G. R., Behm F. G., Williams D. L., Hancock M. L., Mirro J., Jr. Childhood acute lymphoblastic leukemia with chromosomal breakpoints at 11q23. Blood 1989; 73: 1627–1634
   PubMed Web of Science ®Google Scholar
• Pui C.-H. Acute leukemias with the t(4;11)(q21;q23). Leukemia and Lymphoma 1992; 7: 173–179
   PubMed Web of Science ®Google Scholar
• Pui C.-H., Carroll A. J., Raimondi S. C., Shuster J. J., Crist W. M., Pullen D. J. Childhood acute lymphoblastic leukemia with the t(4;11)(q21;q23); An update. Blood 1994; 83: 2384–2385
   PubMed Web of Science ®Google Scholar
• Bloomfield C. D., Seeker-Walker L. M., Goldman A. I., Van Den Berghe H., de la Chapelle A., Ruutu T., Alimena G., Garson O. M., Golomb H. M., Rowley J. D., Kaneko Y., Whang-Peng J., Prigogina E., Philip P., Sandberg A. A., Lawler S. D., Mitelman F. Six-year follow-up of the clinical significance of karyotype in acute lymphoblastic leukemia. Cancer Genet. Cytogenet. 1989; 40: 171–185
   PubMed Web of Science ®Google Scholar
• Arthur D. C., Bloomfield C. D., Lindquist L. L., Nesbit M. E., Jr. Translocation 4;11 in acute lymphoblastic leukemia: clinical characteristics and prognostic significance. Blood 1982; 59: 96–99
   PubMed Web of Science ®Google Scholar
• Mirro J., Kitchingman G., Williams D., Lauzen G. J., Lin C.-C, Callihan T., Zipf T. F. Clinical and laboratory characteristics of acute leukemia with the 4;11 translocation. Blood 1986; 67: 689–697
   PubMed Web of Science ®Google Scholar
• Nagasaka M., Maeda S., Maeda H., Chen H.-L., Kita K., Mabuchi O., Misu H., Matsuo T., Sugiyama T. Four cases of t(4;11) acute leukemia and its myelomonocytic nature in infants. Blood 1983; 61: 1174–1181
   PubMed Web of Science ®Google Scholar
• Parkin J. L., Arthur D. C., Abramson C. S., McKenna R. W., Kersy J. H., Heideman R. L., Brunning R. D. Acute leukemia associated with the t(4;11) chromosomal rearrangement: Ultrastructural and immunologic characteristics. Blood 1982; 60: 1321–1331
   PubMed Web of Science ®Google Scholar
• Crist W. M., Cleary M. L., Grossi C. E., Prasthofer E. F., Heggie G. D., Omura G. A., Carroll A. J., Link M. P., Sklar J. Acute leukemias associated with the 4; 11 chromosome translocation have rearranged immunoglobulin heavy chain genes. Blood 1985; 66: 38–45
   Google Scholar
• Sandoval C., Head D. R., Mirro J., Jr., Behm F. G., Ayers G. D., Raimondi S. C. Translocation t(9;11)(p21;q23) in pediatric de novo and secondary acute myeloblasts leukemia. Leukemia 1992; 6: 513–519
   PubMed Web of Science ®Google Scholar
• Dewald G. W., Morrison-De Lap S. J., Schuchard K. A., Spurbeck J. L., Pierre R. V. A possible specific chromosome marker for monocytic leukemia. Three more patients with t(9;11)(p21;q23) and another with t(11;17)(q24;q21), each with acute monoblastic leukemia. Cancer Genet. Cytogenet. 1983; 8: 203–212
   PubMed Web of Science ®Google Scholar
• Pui C.-H., Raimondi S. C., Murphy S. B., Ribeiro R. C., Kalwinsky D. K., Dahl G. V., Crist W. M., Williams D. L. An analysis of leukemic cell chromosomal features in infants. Blood 1987; 69: 1289–1293
   PubMed Web of Science ®Google Scholar
• Williams D. L., Look A. T., Melvin S. L., Roberson P. K., Dahl G., Flake T., Stass S. New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia. Cell 1984; 36: 101–109
   PubMed Web of Science ®Google Scholar
• Ball E. D., Davis R. B., Griffin J. D., Mayer R. J., Davey F. R., Arthur D. C., Wurster-Hill D., Noll W., Flghetany M. T., Allen S. L., Rai K., Lee E. J., Schiffer C. A., Bloomfield C. D. Prognostic value of lymphocyte surface markers in acute myeloid leukemia. Blood. 1991; 77: 2242–2250
   PubMed Web of Science ®Google Scholar
• Van Lierde S., Mecucci C., Casteels-van Daele M., van den Berghe H. Lineage switch and translocation t(9;11) in acute leukemia. Am. J. Pediatr. Hematol. Oncol. 1989; 11: 20–22
   PubMedGoogle Scholar
• Ackland S. P., Westbrook C. A., Diaz M. O., Le Beau M. M., Rowley J. D. Evidence favoring lineage fidelity in acute nonlymphocytic leukemia: Absence of immunoglobulin gene rearrangements in FAB types M4 and M5. Blood 1987; 69: 87–91
   PubMed Web of Science ®Google Scholar
• Lorenzana A. N., Rubin C. M., Le Beau M. M., Nachman J., Connoly P., Subramanian U., Johnson F. L., McKeithan T. W. Immunoglobulin genes rearrangements in acute lymphoblastic leukemia with the 9; 11 translocation. Genes Chromosomes Cancer 1991; 3: 74–77
   PubMed Web of Science ®Google Scholar
• Hayashi Y., Kobayashi Y., Hirai H., Hanada R., Yamamoto K., Abe T., Sugita K., Nakazawa S., Suetake N., Hoshino H., Kuroume T., Bessho F., Hayakawa H., Takaku F. Immunoglobulin heavy chain gene rearrangements and mixed characteristics in acute leukemias with the 11;19 translocation. Cancer 1988; 61: 712–720
   PubMed Web of Science ®Google Scholar
• Huret J. L., Brizard A., Slater R., Charrin C., Bertheas M. F., Guilhot F., Hählen K., Kroes W., van Leeuwen E., School E. V. D., Beishuizen A., Tanzer J., Hagemeijier A. Cytogenetic heterogeneity in t(11;19) acute leukemia: clinical hematological and cytogenetic analyses of 48 patients-updated published cases and 16 new observations. Leukemia 1993; 7: 152–160
   PubMed Web of Science ®Google Scholar
• McCabe N. R., Burnett R. C., Gill H. J., Thirman M. J., Mbangkollo D., Magdalena K., Van Melle E., Ziemin-Van Der Poel S., Rowley J. D., Diaz M. O. Cloning of cDNAs of the MLL gene that detect DNA rearrangement and altered RNA transcripts in human leukemic cells with 11q23 translocation. Proc. Natl. Acad. Set. USA 1992; 89: 11794–11798
   PubMed Web of Science ®Google Scholar
• Gu Y., Nakamura T., Alder H., Prasad R., Canaani O., Cimino G., Croce C. M., Canaani E. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophia trithorax, to the AF-4 gene. Cell. 1992; 71: 701–708
   PubMed Web of Science ®Google Scholar
• Tkachuk D. C., Kohler S., Cleary M. L. Involvement of a homologue of Drosophia Trithorax by 11q23 chromosomal translocations in acute leukemia. Cell 1992; 71: 691–700
   PubMed Web of Science ®Google Scholar
• Morrissey J., Tkachuk D. C., Milatovich A., Francke V., Link M., Cleary M. L. A serine/proteine-rich protein is fused to HRX in t(4;11) acute leukemias. Blood 1993; 81: 1124–1131
   PubMed Web of Science ®Google Scholar
• Nakamura T., Alder H., Gu Y., Prasad R., Canaani O., Kamada N., Gale R. P., Lange B., Crist W. M., Nowell P. C., Croce C. M., Canaani E. Gene on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc. Nail. Acad. Sci. USA 1993; 90: 4631–4635
   PubMed Web of Science ®Google Scholar
• Yamamoto K., Seto M., Komatsu H., Lida S., Akao Y., Kojima S., Kodera Y., Nakazawa S., Ariyoshi Y., Takahashi T., Ueda R. Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia. Oncogene 1993; 8: 2617–2625
   PubMed Web of Science ®Google Scholar
• Hunger S. P., Sklar J., Link M. P. Acute lymphoblastic leukemia occurring as a second malignant neoplasm in childhood: re port of three cases and review of the literature. J. Clin. Oncol. 1992; 10: 156–163
   PubMed Web of Science ®Google Scholar
• Gill Super H. J., McCabe N. R., Thirman M. J., Larson R. A., Le Beau M. M., Pederson-Bjergaard J., Philip P., Diaz M. O., Rowley J. D. Rearrangement of the MLL gene in. therapy-related acute myelod leukemia in patients previously treated with agents targeting DNA-topoisomerase II. Blood 1993; 82: 3705–3711
   PubMed Web of Science ®Google Scholar
• Thirman M. J., Gill H. J., Burnett R. C., Mbangkollo D., McCabe N. R., Kobayashi H., Ziemin-Van Der Poel S., Kaneko Y., Morgan R., Sandberg A. A., Chaganti R. S. K., Larson R. A., Le Beau M. M., Diaz M. O., Rowley J. D. Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N. Engl. J. Med. 1993; 329: 909–914
   PubMed Web of Science ®Google Scholar
• Sorensen P. H., Chen C. S., Smith F. O., Arthur D. C., Domer P. H., Bernstein I. D., Korsmeyer S. J., Hammond G. D., Kersey J. H. Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes. J. Clin. Invest. 1994; 93: 429–437
   PubMed Web of Science ®Google Scholar
• Kobayashi H., Espinosa R., III, Thirman M., Gill H. J., Fernald A. A., Diaz M. O., Le Beau M. M., Rowley J. D. Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization. Blood 1993; 82: 547–551
   PubMed Web of Science ®Google Scholar
• Lo Coco F., Mandelli F., Breccia M., Annino L., Guglielmi C., Petti M. C., Testi A. M., Alimena G., Croce C. M., Canaani E., Cimino G. Southern blot analysis of ALL-1 rearrangement at chromosome 11q23 in acute leukemia. Cancer Res. 1993; 53: 3800–3803
   PubMed Web of Science ®Google Scholar
• Ziemin-van der Poel S., McCabe N. R., Gill H. J., Espinosa R., III, Patel Y., Harden A., Rubinelli P., Smith S. D., Le Beau M. M., Rowley J. D., Diaz M. O. Identification of a gene, MLL that spans the breakpoint in 11q23 translocation associated with human leukemias. Proc. Nail. Acad. Sci. USA 1991; 88: 10735–10739
   PubMed Web of Science ®Google Scholar
• Corral J., Forster A., Thompson S., Lampert F., Kaneko Y., Slater R., Kroes W. G., van der Schoot C. E., Ludwig W.-D., Karpas A., Pocock C., Cotter F., Rabbitts T. H. Acute leukemias of different lineage have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation. Proc. Natl. Acad. Sci. USA 1993; 90: 8538–8542
   PubMed Web of Science ®Google Scholar
• Morgan G. J., Cotter F., Katz F. E., Ridge S. A., Domer P., Korsmeyer S., Wiedemann L. M. Breakpoints at 11q23 in infant leukemias with the t(11;19)(q23;p13) are clustered. Blood 1992; 80: 2172–2175
   PubMed Web of Science ®Google Scholar
• Kearney L., Bower M., Gibbons B., Das S., Chaplin T., Nacheva E., Chessells J. M., Reeves B., Riley J. H., Lister T. A., Young B. D. Chromosome 11q23 translocation in both infant and adult acute leukemias are detected by in situ hybridization with a yeast artificial chromosome. Blood 1992; 80: 1659–1665
   PubMed Web of Science ®Google Scholar
• Yamamoto K., Seto M., Iida S., Komatsu H., Kamada N., Kojima S., Kodera Y., Nakazawa S., Saito H., Takahashi T., Ueda R. A reverse transcriptase-polymerase reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities. Blood 1994; 83: 2912–2921
   PubMed Web of Science ®Google Scholar
• Chen Z., Guidez F., Rousselot P., Agadir A., Chen S. J., Wang Z. Y., Degos L., Zelent A., Waxman S., Chomienne C. PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors. Proc. Natl. Acad. Sci. USA 1994; 91: 1178–1182
   PubMed Web of Science ®Google Scholar
• Lu D., Yunis J. J. Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3. Nucleic Acids Res. 1992; 20: 1967–1972
   PubMed Web of Science ®Google Scholar
• Akao Y., Seto M., Yamamoto K., Iida S., Nakazawa S., Inazawa J., Abe T., Takahashi T., Ueda R. The RCK gene associated with t(11;14) translocation distinct from the MLL/ALL-I gene with t(4;11) and t(11;19) translocations. Cancer Res. 1992; 52: 6083–6087
   PubMed Web of Science ®Google Scholar
• Burnett R. C., Espinosa R. I., Shows T. B., Eddy R. L., Le Beau M. M., Rowley J. D., Diaz M. O. Molecular analysis of a t(11;14)(q23;q11) from a patient with null-cell acute lymphoblastic leukemia. Genes Chromosomes Cancer 1993; 7: 38–46
   PubMed Web of Science ®Google Scholar
• Kobayashi H., Espinosa R., III, Thirman M. J., Davis E. M., Diaz M. O., Le Beau M. M., Rowley J. D. Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization. Blood 1993; 81: 3027–3033
   PubMed Web of Science ®Google Scholar
• Cherif D., Der-Sarkissian H., Derré J., Tokino T., Nakamura Y., Berger R. The 11q23 breakpoint in acute leukemia with t(11;19)(q23;p13) is distal to those of t(4;11), t(6;11) and t(9;11). Genes Chromosomes Cancer 1992; 4: 107–112
   PubMed Web of Science ®Google Scholar
• Mitani K., Sato Y., Kobayashi Y., Shibasaki Y., Kasuga M., Inaba T., Hayashi Y., Miura Y., Miyazono K., Hirai H., Urabe A., Takaku F. Heterogeneity in the breakpoints of chromosome 19 among acute leukemia patients with the t(11;19)(q23;p13) translocation. Am. J., Hematol. 1989; 31: 253–257
   PubMed Web of Science ®Google Scholar
• Saltman D. L., Mellentin J. D., Smith S. D., Cleary M. L. Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization. Genes Chromosomes Cancer 1990; 2: 259–265
   PubMed Web of Science ®Google Scholar
• Pui C.-H., Behm F. G., Raimondi S. C., Dodge R. K., George S., Rivera G. K., Mirro J., Jr., Kalwinsky D. K., Dahl G. V., Murphy S. B., Crist W. M., Williams D. L. Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia. N. Engl. J. Med. 1989; 321: 136–142
   PubMed Web of Science ®Google Scholar
• Pui C.-H., Ribeiro R. C., Hancock M. L., Rivera G. K., Evans W. E., Raimondi S. C., Head D. R., Behm F. G., Mahmoud H., Sandlund J. T., Crist W. M. Acute myelod leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia. N. Engl. J. Med 1991; 325: 1682–1687
   PubMed Web of Science ®Google Scholar
• Pedersen-Bjergaad J., Philip P., Larsen S. O., Jensen G., Byrsting K. Chromosome aberrations and prognostic factors in therapy-related myelodysplasia and acute nonlymphocytic leukemia. Blood 1990; 76: 1083–1091
   PubMed Web of Science ®Google Scholar
• Pedersen-Bjergaard J., Philip P., Larsen S. O., Andersson M., Daugaard G., Ersbell J., Hansen S. W., Hou-Jensen K., Nielsen D., Sigsgaard T. C., Specht L., Østerlind K. Therapy-related myelodysplasia and acute myeloid leukemia. Cytogenetic characteristics of 115 consecutive cases and risk in seven cohorts of patients treated intensively for malignant disease in the Copenhagen series. Leukemia. 1993; 7: 1975–1986
   PubMed Web of Science ®Google Scholar
• Ratain M. J., Kaminer L. S., Bitran J. D., Larson R. A., Le Beau M. M., Skosey C., Purl S., Hoffman P. C., Wade J., Vardiman J. W., Daly K., Rowley J. D., Golomb H. M. Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung. Blood 1987; 70: 1412–1417
   PubMed Web of Science ®Google Scholar
• De Vore R., Whitlock J., Hainsworth J. D., Johnson D. H. Therapy-related acute nonlymphocytic leukemia with monocytic features and rearrangement of chromosome 11q. Ann Int Med. 1989; 110: 740–742
   PubMedGoogle Scholar
• Weh H. J., Kabisch H., Landbeck G., Hossfeld D. K. Translocation (9;11)(p21;q23) in a child with acute monoblastic leukemia following 2 1/2 years after successful chemotherapy for neuroblastoma. J. Clin. Oncol. 1986; 4: 1518–1520
   PubMed Web of Science ®Google Scholar
• Prieto F., Palau F., Badia L., Beneyto M., Perez-Sirvent M. L. A., Castel V. 11q23 abnormalities in children with acute nonlymphocytic leukemia(M4-M5). Association with previous therapy. Cancer Genet. Cytogenet. 1990; 45: 1–11
   PubMed Web of Science ®Google Scholar
• Rubin C. M., Arthur D. C., Woods W. G., Lange B. J., Nowell P. C., Rowley J. D., Nachman J., Bostrom B., Baum E. S., Suarez C. R., Shah N. R., Morgan E., Maurer H. S., McKenzie S. E., Larson R. A., Le Beau M. M. Therapy-related myelodysplastic syndrome and acute myelod leukemia in children: Correlation between chromosomal abnormalities and prior therapy. Blood. 1991; 78: 2982–2988
   PubMed Web of Science ®Google Scholar
• Rowley J. D., Golomb H. M., Vardiman J. W. Nonrandom chromosome abnormalities in acute leukemia and dysmyelopoetic syndromes in patients with previously treated malignant disease. Blood 1981; 58: 759–767
   PubMed Web of Science ®Google Scholar
• Pedersen-Bjergaard J., Sigsgaard T. C, Nielsen D., Gjedde S. B., Philip P., Hansen M., Larsen S. O., Rørth M., Mouridsen H., Dombernowsky P. Acute monocytic or myelomonocytic leukemia with balanced chromosome translocations to band 11q23 after therapy with 4-epi-doxorubicin and cisplatin or cyclophosphamide for breast cancer. J. Clin. Oncol. 1992; 10: 144–1451
   Google Scholar
• Kobayashi Y., Yang J., Shindo E., Tojo A., Tani K., Ozawa K., Asano S. HRX gene rearrangement in acute lymphoblastic leukemia after adjuvant chemotherapy of breast cancer. Blood 1993; 82: 3220–3221
   PubMed Web of Science ®Google Scholar
• Sugita K., Furukawa T., Tsuchida M., Okawa Y., Nakazawa S., Akatsuka J., Ohira M., Nishimura K. High frequency of etoposide(VP-16) related secondary leukemia in children with non-Hodgkin's lymphoma. Am. J. Pediatr. Hematol. Oncol 1993; 15: 99–104
   PubMedGoogle Scholar
• Sandoval C., Pui C.-H., Bowman L. C., Heaton D., Hurwitz C. A., Raimondi S. C., Behm G. F., Head D. R. Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation. J. Clin. Oncol. 1993; 11: 1039–1045
   PubMed Web of Science ®Google Scholar
• Pedersen-Bjergaard J., Philip P. Balanced translocation involving chromosome bands 11q23 and 21q22 are highly characteristic of myelodysplasia and leukemia following therapy with cytostatic agents targeting at DNA-topoisomerase II. Blood 1991; 78: 1147–1148
   PubMed Web of Science ®Google Scholar
• Bae Y.-S., Kawasaki I., Ikeda H., Liu L. F. Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vivo. Proc. Natl. Acad. Sci. USA 1988; 85: 2076–2080
   PubMed Web of Science ®Google Scholar
• Negrini M., Felix C. A., Martin C., Lange B. J., Nakamura T., Canaani E., Croce C. M. Potential topoisomerase II DNA-binding site at the breakpoints of a t(9;11) chromosome translocation. Cancer Res. 1993; 53: 4489–4492
   PubMed Web of Science ®Google Scholar
• Weiss R. B. The anthracyclines: Will we find a better doxorubicin?. Seminars Oncol. 1992; 670–686
   PubMed Web of Science ®Google Scholar
• Kapelushnik J., Dubé I., Wilson P., Greenberg M. Acute lymphoblastic leukemia with t(4;11) translocation after osteogenic sarcoma. Cancer 1990; 67: 2887–2889
   Web of Science ®Google Scholar
• Pedersen-Bjergaard P., Rowley J. D. The balanced and unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation. Blood 1994; 83: 2780–2786
   PubMed Web of Science ®Google Scholar
• Hudson M. M., Raimondi S. C., Behm F. G., Pui C.-H. Childhood acute leukemia with t(11;19)(q23;p13). Leukemia 1991; 5: 1064–1068
   PubMed Web of Science ®Google Scholar