51
Views
11
CrossRef citations to date
0
Altmetric
Original Article

G-CSF in the Biology and Treatment of Acute Myeloid Leukemias

&
Pages 423-428 | Received 01 Oct 1994, Published online: 01 Jul 2009

References

  • Nicola N.A. Granulocyte colony-stimulating factor. Immunology Series 1990; 49: 77–109
  • Metcalf D. The hemopoietic colony stimulating factors. Elsevier. 1984
  • Tweardy D.J., Cannizzaro L.A., Palumbo A.P., Shane S., Heubner K., Vantuinen P., Ledbetter D.H., Finan J.B., Nowell P.C., Rovera G. Molecular cloning and characterization of acDNA for human granulocyte colony-stimulating factor (G-CSF) from a glioblastoma multiforme cell line and localization of the G-CSF gene to chromosome band 17q21. Oncogene Res. 1987; 1: 209–220
  • Simmers R.N., Webber L.M., Shannon M.F., Garson O.M., Wong G., Vadas M.A., Sutherland G.R. Localization of G-CSF gene on chromosome 17 proximal to the breakpoint in the t(15;17) in acute promyelocytic leukemia. Blood 1987; 70: 330–332
  • Kanda N., Fukushige S.I., Murotsu T., Yoshida M.C., Tsuchiya M., Asano S., Kazior Y., Nagata S. Human gene coding for granulocyte colony-stimulating factor is assigned to the q21-q22 region of the chromosome 17. Somat. Cell. Mol. Cent. 1987; 13: 679–684
  • Nicola N.A., Metcalf D. Binding of differentiation-inducer, granulocyte colony-stimulating factor, to responsive but not to unresponsive leukemic cell lines. Proc. Natl. Acad. Sci. 1984; 81: 3765–3769
  • Nicola N.A., Metcalf D. Binding of 125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells. J. Cell. Fisiol. 1985; 124: 313–321
  • Nicola N.A., Begley C.G., Metcalf D. Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells. Nature 1985; 314: 626–628
  • Hara K., Suda T., Suda J., Ihle J.N., Nagataka S., Miura Y., Saito M. Bipotential murine cell line (NFS60) that is responsive to IL3, GM-CSF, G-CSF and erythropoietin. Exp. Hematol. 1988; 16: 256–261
  • Begley C.C., Metcalf D., Nicola N.A. Primary human myeloid leukemia cells: comparative responsiveness to proliferative stimulation by GM-CSF or G-CSF and membrane expression of CSF receptors. Leukemia 1987; 1: 1–8
  • Begley C.G., Metcalf D., Nicola N.A. Binding characteristics and proliferative action of purified granulocyte colony-stimulating factor (G-CSF) on normal and leukemic human promyelocytes. Exp. Hematol. 1988; 16: 71–79
  • Nicola N.A., Metcalf D. The colony-stimulating factors and myeloid leukemia. Cancer Sum. 1985; 4: 789–815
  • Robinson B.E., Quesenberry P.J. Hematopoietic growth factors: overview and clinical applications. Parts I, II and III. Am. Med. Sci. 1990; 300: 163–170; 237–244, 311–321
  • Berdel W.E., Danhauser-Riedel R., Steinhauser R., Winton E.F. Various human hemopoietic growth factors (intcr-leukin-3, GM-CSF, G-CSF) stimulate clonal growth of non-hemopoietic tumor cells. Blood 1989; 73: 80–83
  • Delwel R., Salem M., Dorssers L., Wagemaker G., Clark S., Lowenberg B. Growth regulation of human acute myeloid leukemia: effects of five recombinant hemopoietic factors in serum-free culture system. Blood 1988; 72: 1944
  • Miyauchi J., Kelleher C.A., Yang Y.C., Wong G.C., Clark S.C., Minden M.D., Minkin S., McCulloch E.A. The effects of three recombinant growth factors, IL3, GM-CSF, and G-CSF on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture. Blood 1987; 70: 1987, 657
  • Pebusque M.J., Pebusque M.J., Lopez M., Torres H., Carotti A., Guilbert L., Mannoni P. Growth response of human myeloid leukemia cells to colony-stimulating factors. Eq. Hematol. 1988; 16: 360
  • Vellenga E., Ostapovicz D., O'Rourke B., Griffin J.D. Effects of recombinant IL3, GM-CSF and G-CSF on the proliferation of leukemic clonogenic cells in short-term and long-term cultures. Leukemia 1987; 1: 584
  • Löwenberg B. Effects (of recombinant multi-CSF, GM-CSF, G-CSF and M-CSF on the proliferation and maturation of human AML in vitro. Blood Cells 1988; 14: 539–549
  • Salem M., Delwel R., Mahmoud M.A., Clark S., Elbaz E.M., Lowenberg B. Maturation of human acute myeloid leukemia in vitro: the response to five recombinant haemopoietic growth factors in a serum-free system. Br. J. Hematol. 1989; 71: 363–369
  • Begley C.G., Metcalf D., Nicola N.A. Purified colony stimulating factors (G-CSF and GM-CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity. Int. J. Cancer 1987; 39: 99
  • Touw I., Donath J., Pouwels K., van Buitenen C., Schipper P., Santini V., Hagemeijer A., Delwel R. Acute myeloid leukemia with chromosomal abnormalities involving the 21q22 region identified by their in vitro responsiveness to interleukine 5. Leukemia 1991; 8: 687
  • Huang F., Zhao H.P., Gao Z., Dai M.M., Fan L.L. Recombinant human G-CSF and retinoic acid synergistically induce granulocyte differentiation of human promyelocytic leukemic cells. Chin. Med. J. Engl. 1991; 105(9)707–12
  • Backx B., Broeders L., Rot F.J., Lowenberg B. Positive and negative effects of tumor necrosis factor on colony growth from highly purified normal marrow progenitors. Leukemia 1991; 5: 66–71
  • Salem M., Delwel R., Touw I., Mahmoud L.A., Elbaz E.M., Lowenberg B. Modulation of colony stimulating factor (CSF) dependent growth of acute myeloid leukemia by tumor necrosis factor. Leukemia 1990; 4: 37–43
  • Lowenberg B., Touw P. Hematopoietic growth factors and their receptors in acute leukemia. Blood 1993; 81: 281–292
  • Koeffler K., Gasson J., Ranyard G., Souza L., Shepard M., Munker R. Recombinant human TNFα stimulates production of granulocyte colony-stimulating factor. Blood 1987; 70: 55–61
  • Delwel R., van Buitenen C., Lowenberg B., Touw I.P. Involvement of tumor necrosis factor (TNF) receptors p55 and p75 in TNF responses of acute myeloid leukemia blasts in vitro. Blood 1992; 80: 1798–1803
  • Vellenga E., de Wolf J Th.M., Beentjes J.A.M., Esselink M.T., Smith J.W., Halie M.R. Divergent effects of inter-leukin-4 (IL4) on the granulocyte colony-stimulating factor and IL3 supported myeloid colony formation from normal and leukemic bone marrow cells. Blood 1990; 75: 633–39
  • Tessier N., Hoang T. Transforming growth factorβ inhibits the proliferation of the blast cells of acute myeloblastic leukemia. Blood 1988; 72: 155–65
  • Nara N., Tohda S., Nagata K., Suziki T., Yamashita Y. Inhibition of the in vitro growth of blast progenitors from acute myeloblastic leukemia patients by transforming growth factor beta. Leukemia 1989; 3: 572–77
  • Keller J.R., Jacobsen S.E., Dubois C.M., Hestdal K., Nuscetti F.W. Transforming growth factor beta: a bidirectional regulator of hemopoietic cell growth. Int. J. Cell. Cloning 1992; 10: 2–9
  • Murohashi I., Tohda S., Suzuki T., Nagata K., Yamashita Y., Nara N. Autocrine growth mechanism of the progenitors of the blast cells in acute myeloblastic leukemia. Blood 1989; 74: 35–40
  • Delwel R., Schipper P., van Buitenen C., van Agthoven T., Touw I., Löwenberg B. Comparative analysis of IL1 regulated and spontaneous growth of acute myeloid leukemia in vitro. Bone Marrow Transplant. 1990; 6: 22
  • Bronchud M.H., Scarffe N., Thatcher D., Crowther L.M., Alton K., Testa N.G., Dexter T'.M. Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer. Br. J. Cancer 1987; 56: 805–816
  • Gabrilove J.L., Jakubowski A, Scher H., Stemberg C., Wong G., Grous J., Yagoda A., Fain K., Mooer M.A.S., Clarkson B., Oettge H.F., Alton K., Welte K., Sousa L. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium. N. Engl. J. Med. 1988; 318: 1414–1422
  • Crawford J., Ozer H., Stoller R., Johnson D., Lyman G., Tabbara I., Kris M., Grous J., Picozzi V., Rausch G., Smith R., Gradishar W., Yahanda A., Vincent M., Stewart M., Glaspy J. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small cell lung cancer. N. Engl. J. Med. 1991; 325: 164–170
  • Ogawa M., Masaoka T., Takaku F., Nakashima M. A phase III study of KRN 8601 (rhG-CSF) on neutropenia induced by chemotherapy for malignant lymphoma-a multiinstitutional placebo controlled double-blind comparative study. Gan to Kagaku Ryoho 1990; 17: 367–373
  • Yoshida T., Nakamura S., Otake S., Okafuji K., Kubayashi K., et al. Effect of granulocyte colony-stimulating factor on neutropenia due to chemotherapy for non-Hodgkins lymphoma. Cancer 1990; 66: 1904–1909
  • Tafuri A., Andreeff H. Kinetic rationale for cytokine-induced recruitment of myeloblastic leukemia followed by cycle-specific chemotherapy in vitro. Leukemia 1990; 4: 826–834
  • Negrin R.S., Haeuber D.H., Nagler A., Kobayashi Y., Sklar J., Donlon T., Souza L.M., Greenberg P.L. Treatment of myelodysplastic syndromes with human granulocyte colony-stimulating factor. Exp. Hematol. 1988; 16: 519–26
  • Thompson J.A., Lee D.J., Kidd P., Rubin E., Kaufmann J., Bonnem E., Fefer A. Subcutaneous granulocyte colony-stimulating factor in patients with myelodysplastic syndrome: toxicity, pharmacokinetics and hematological effects. J. Clin. Oncol. 1989; 7: 629–35
  • Ohno R., Tomanoga M., Kobayashi T., Kanamaru A., Shirakawa S., Masaoka T., Omine M., Oh H., Sakai Y., Hirano M., Yokomaku S., Nakayama S., Yoshida Y., Miura A.B., Morishima Y., Dohy H., Niho Y., Hamajima N., Takaku F. Effect of granulocyte colony-stimulating factor after intensive induction therapy in relapsed or refractory leukemia. N. Engl. J. Med. 1990; 871–877
  • Takauji R., Tohyama K., Ueda T., Nakamura T. Enhancement of cytosine arabinoside cytotoxicity by granulocyte/macrophage colony-stimulating factor and granulocyte colony-stimulating factor in a human myeloblastic leukemia cell line. Jpn. J. Cancer Res. 1993; 84: 445450
  • Gandhi V., Estey E., Plunkett W. Biological modulation of nucleoside analog metabolism by granulocyte colony-stimulating factor during therapy. Blood 1993; 82: 354, Suppl. 1
  • Tosi P., Visani G., Ottaviani E. Fludarabine + ARA-C + G-CSF: Cytotoxic effect and induction of apoptosis on fresh acute myeloid leukemia cells. Leukemia 1994, in press
  • Ohno R., Naoe T., Kanamaru A., Yoshida M., Hiraoka A., Kobayashi T., Ueda T., Minami S., Moroshima Y., Saito Y., Furusawa S., Imai K., Takemoto Y., Miura Y., Teshima H., Hamajima N. Konseisho Leukemia Stoudy Group., A double-blind controlled study of granulocyte colony-stimulating factor started two days before induction chemotherapy in refractory acute myeloid leukemia. Blood 1994; 83: 2086–93
  • Estey E., Thall P., Andreef M., Kantarjian H., O'Brien S., Escudier S., Robertson L.E., Koller C., Komblau S., Pierce S., Freireich E.J., Deisseroth A., Keating M. Use of G-CSF before, during and after fludarabine + ara-C induction therapy of newly diagnosed AML or MDS: comparison with fludarabine + ara-C without G-CSF. J. Clin. Oncol. 1994; 12: 671–678
  • Ishikawa J., Yoshimura M., Matsunashi T., Tominaga N., Teshima H., Hiraoka A., Nakamura H., Shibata H., Masaoka T., Takaku F. Clinical effect of granulocyte colony-stimulating factor on neutrophils and leukemic cells in myelogenous leukemia. Jpn. J. Clin. Oncol. 1991; 21: 169–175
  • Morstyn G., Souza L.M., Keech J., Campbell L., Alton N.K., Green M., Sheridan W., Metcalf D., Fox R. Effect of granulocyte colony-stimulating factor on neutropenia induced by cytotoxic chemotherapy. Lancet 1988; 1: 667–672
  • Teshima H., Ishikawa J., Kitayama H., et al. Clinical effects of recombinant human granulocyte colony-stimulating factor in leukemia patients: a phase I/II study. Exp. Hematol. 1989; 17: 853–858
  • Bodey G.P., Buckley M., Sathe Y.S., Freireich E.J. Quantitative relationship between circulating leukocytes and infections in patients with acute leukemia. Ann. Inf. Med. 1966; 64: 238–240
  • Estey H. Use of colony-stimulating factors in the treatment of acute myeloid leukemia. Blood 1994; 83: 2015–2019
  • Gulati S.C. Did we focus on the most important issues in the use of growth factors and stem-cell transplantation?. J. Clin. Onc. 1994; 12: 650–652
  • Sheridan W.P., Begley C.G., Juttner C.A., Szer J., To L.B., Maher D., McGrath K.M., Morstyn G., Fox R.M. Effect of peripheral blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 1992; 339: 640–644
  • Sheridan W.P., Morstyn G., Wolf M., Dodds A., Lusk J. Granulocyte colony stimulating factor and neutrophil recovery after high-dose chemotherapy and autologous bone marrow transplantation. Lancet 1989; 2: 891–894
  • Peters W.P., Kurtzburg J., Atwater S. Comparative effect of r-HUG-CSF and r-HuGM-CSF on hemopoietic reconstitution and granulocyte function following high-dose chemotherapy and autologous bone marrow transplantation (ABMT). Proceedings of the American Society of Clinical Oncology 1989; 8: 702A
  • Peters W.P. The effect of recombinant human colony stimulating factors on hemopoietic reconstitution following autologous bone marrow transplantation. Sem. Hematol. 1989; 26: 18–23, 2 Suppl. 2
  • Gisselbrecht C., Prentice G., Bacigalupo A., Biron P., Milpied N., Rubie H., Cunningham D., Legros M., Pico J.L., Linch D.C., Burnett A.K., Scarffe J.H., Siegert W., Yver A. A phase III randomized placebo-controled study in 315 pediatric and adult autologous or allogeneic bone marrow transplantation with lenograstim 5μg/Kg/day (glicosilated rHu-G-CSF). Blood 1993; 82: 445a, suppl. 1
  • Schriber J.R., Nelson J.C., Gwynn D.L., Negrin R.S., Blume K.G. Granulocyte colony-stimulating factor (G-CSF) following allogeneic bone marrow transplantation. Blood 1993; 82: 286a, suppl. 1
  • Schwartzberg L., Birch R., Heffernan M., West W. G-CSF is an effective supportive modality in peripheral blood stem cell (PBSC) transplantation. Blood 1993; 82: 286a, suppl. 1
  • Vredenburg J.J., Waters-Pick B., Kurtzberg J., Drago S., Ross M., Hussein A., Peters W.P. A single 6-hour (HR) steady state leukapheresis is sufficient for collection of peripheral blood progenitor cells (PBSC) after G-CSF. Blood 1993; 82: 349a, suppl. 1.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.