Impaired Activation of Phospholipase D in Polycythaemia Vera-Implications for the Pathogenesis of the Disease?

References

• Adamson J.W., Fialkow P.J., Murphy J., Prchal J.F., Steinmann L. Polycythemia Vera: stem cell and probable clonal origin of the disease. N. Eng. J. Med. 1976; 295: 913–916
   PubMed Web of Science ®Google Scholar
• Damashek W. Some speculations on the myeloproliferative syndromes. Blood. 1951; 6: 372–375
   PubMed Web of Science ®Google Scholar
• Raskind W.H., Jacobson R., Murphy S., Adamson J., Fialkow P.J. Evidence for the involvement of B lymphoid cells in polycythemia Vera and essential thrombocythemia. J. Clin. Invest. 1985; 75: 1388–1390
   PubMed Web of Science ®Google Scholar
• Lucas G.S., Padua R.A., Masters G.S., Oscier D.G., Jacobs A. The application of X-chromosome gene probes to the diagnosis of myeloproliferative disease. Br. J. Haematol. 1989; 72: 530–533
   PubMed Web of Science ®Google Scholar
• Anger B., Janssen J.W.G., Schrezenmeier H., Hehlmann R., Heimpel H., Bartram C.R. Clonal analysis of chronic myeloproliferative disorders using X-linked DNA polymorphism. Leukaemia Res. 1990; 4: 258–261
   Google Scholar
• Gilliland D.G., Blanchard K.L., Levy J., Perrin S., Bunn H.F. Clonality in myeloproliferative disorders using X-linked DNA polymorphism. Proc. Nat. Acad. Sci. USA 1991; 88: 6448–6452
   Web of Science ®Google Scholar
• Tsukamoto T., Morita K., Maehara T., Okamoto K., Sakai H., Karasawa M., Naruse T., Omine M. Clonality in chronic myeloproliferative disorders defined by X-chromosome linked probes: demonstration of hetreogeneity in lineage involvement. Br. J. Haematol. 1904; 86: 253–58
   Web of Science ®Google Scholar
• Baldridge C.W., Gerard R.W. The extra respiration of phagocytosis. Am. J. Physiol. 1933; 103: 235–36
   Google Scholar
• Babior B.M., Kipnes R.S., Curnutte J.T. Biological defense mechanisms. The production by leukocytes of superoxide. a potential bactericidal agent. J. Clin. Invest 1973; 52: 741–44
   PubMed Web of Science ®Google Scholar
• Rossi F., Zatti M. Biomedical aspects of phagocytosis in polymorphonuclear leukocytes. NADP and NADPH oxidation by the granules of resting and phagocytozing cells. Experentia 1964; 20: 21–13
   PubMedGoogle Scholar
• McPhail L.C., Qualliotine-Mann O., Agwu end D.E., McCall C.E. Phospolipases and activatton of the NADPH oxidase. Eur. J. Haematol. 1993; 51: 294–300
   PubMed Web of Science ®Google Scholar
• Bokoch G.M., Knaus U.G. Ras-related GTP-binding proteins and leukocyte signal transduction. Curr. Opin Hamatol. 1994; 1: 53–60
   PubMedGoogle Scholar
• Pai J.K., Siegel Egan R. W M.I., Billah M.M. Phospholipase D catalyzes phospholipid metabolism in chemotactic-stimulated HL-60 granulocytes. J. Biol. Chem. 1988; 263: 12472–77
   PubMed Web of Science ®Google Scholar
• Rossi F., Grzeskowiak Della M., Bianca V., Calzetti F., Gandini G. Phosphatidic acid and not diacylglycerol generated by phospholipase D is functionally linked to the activation of NADPH oxidase by fMLP in human neutrophils. Biochem. Biophys. Rev. Commun. 1990; 168: 320–27
   PubMed Web of Science ®Google Scholar
• Olson S.C., Tyapi S.R., Lambeth J.D. Fluoride activates diradylglycerol and suproxide generation in human neutrophils via PLD/PA phosphohydrolase-dependent and -independent pathways. FEBS Lett. 1990; 272: 19–14
   PubMed Web of Science ®Google Scholar
• Bourgoin S., Plante E., Gaudry M., Naccache P.H., Borgeat P., Poubelle P.E. Involvement of phospholipase D in the mechanism of action of granulocyte-macrophage colony-stimulating factor (GM-CSF): Priming of human neutrophils in vitro with GM-CSF is associated with accumulation of phosphatidic acid and diradylglycerol. J. Exp. Med. 1990; 172: 767–77
   PubMed Web of Science ®Google Scholar
• Agwu D.E., McPhail L.C., Sozzani S., Bass D.A., McCall C.E. Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase. J. Clin. Invest. 1991; 88: 531–39
   PubMed Web of Science ®Google Scholar
• Rauldry S.A., Bass D.A., Cousart S.L., McCall C.E. Tumor necrosis factor priming of phospholipase D in human neutrophils. Correlation between phosphatidic acid production and superoxide generation. J. Biol. Client. 1991; 266: 4173–79
   Web of Science ®Google Scholar
• Ghosh M.L., Hudson G., Blackburn E.K. Skin window studies in polycythaemia rubra vera. Br. J. Haematol. 1975; 29: 461–67
   PubMed Web of Science ®Google Scholar
• McCall Caves C.E., Cooper and J.R., de Chatelet L. Functional characteristics of human toxic neutrophils. J. Infect. Dis. 1971; 124: 68–75
   PubMed Web of Science ®Google Scholar
• Jungi W.F., Meuret G., Senn H.J. Granulozytenclearence and granulozytenkinetik bei myeloproliferativen Syndromen. Schwiez. Med Wschr. 1974; 104: 133–25
   PubMedGoogle Scholar
• La Corberand J., Harrague P., De Larrad B., Nguyen F., Pris J. Phagocytosis in myeloproliferative disorders. Am J. Clin., Pathol. 1980; 74: 301–05
   PubMed Web of Science ®Google Scholar
• Laharrague orherand P FC., Fillola J.X.G., Boneu B.P., Pris J.F. Simultaneous study of platelets and phagocytes in myeloproliferative disorders. Biomed. Pharmacother. 1984; 38: 462–65
   PubMed Web of Science ®Google Scholar
• Gilbert H.S., Ward L. Augmented granulocyte adherence: an intrinsic abnormality in polycythemia vera. Blood. 1976; 48: 971a
   Web of Science ®Google Scholar
• Hopen G. Granulocyte and platelet adhesiveness in maliginant paraproteinemia, leukemia and mycloproliferative diseases. Scand. J. Haematol. 1981; 27: 339–45
   PubMedGoogle Scholar
• Cooper M.R., De Chatelet L.R., McCall C.E., Spurr C.L. The activated phagocyte of polycythemia vera. Blood. 1972; 40: 366–74
   PubMed Web of Science ®Google Scholar
• Ashburn P., Cooper M.R., McCall C.E., De Chatelet L.R. Nitroblue tetrazolium reduction: false positive and false negative results. Blood. 1973; 41: 921–25
   PubMed Web of Science ®Google Scholar
• Samuelsson J., Lindström P., Palmblad J. Stimulus-specific defect in oxidative metabolism of polymorphonuclear granulocytes in polycythemia vera. Eur. J. Haematol. 1988; 41: 454–458
   PubMed Web of Science ®Google Scholar
• Samuelsson J., Berg A. Further studies of the defective stimulus-response coupling for the oxidative burst in neutrophils in polycythemia vera. Eur. J. Haematol. 1991; 47: 239–245
   PubMed Web of Science ®Google Scholar
• Samuelsson J., Hansson A., Rosendahl K., Palmblad J. Superoxide anion production and phospholipase D mediated generation of diacylglycerol are subnormal after N-formyl-methionyl-leucyl-phenylalanine stimulation of polymorphonuclear granulocytes in polyeythemia vera. J. Lab. Clin. Med. 1993; 121: 310–19
   PubMedGoogle Scholar
• Odeberg H., Olofsson T., Olsson I. Granulocyte function in chronic granulocytic leukaemia. J. Bactericidal and metabolic capabilities during phagocytosis in isolated granulocytes. Br. J. Haematol. 1975; 29: 427–441
   PubMed Web of Science ®Google Scholar
• Olofsson T., Odeberg H., Olsson I. Granulocyte function in chronic granulocytic leukemia. II. Bactericidal capacity, phagocytic rate. oxygen consumption, and granule protein composition in isolated granulocytes. Blood. 1976; 48: 581–593
   PubMed Web of Science ®Google Scholar
• El-Maallem H., Fletcher J. Defective hydrogen peroxide production in chronic granulocytic leukaemia neutrophils. Br. J. Haematol. 1979; 41: 49–55
   PubMed Web of Science ®Google Scholar
• Gallin J.I., Jacobson R.J., Seligmann B.E., Metcalf J.A., McKay J.H., Sacher R.A., Malech H. A neutrophil marker reveals two groups of chronic myelogenous leukemia and its absence may he a marker for disease progression. Blood. 1986; 68: 343–346
   PubMed Web of Science ®Google Scholar
• Samuelsson J., Forslid J., Hed J., Palmblad J. Studies of neutrophil and monocyte oxidative responses in polycytaemia vera and related myeloproliferative disorders. Br. J. Haematol. 1994; 87: 464–70
   PubMed Web of Science ®Google Scholar
• Agwu D.E., McPhail L.C., Chabot M.C., Daniel L.W., Wykle R.L., McCall C.E. Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils. J. Biol Chem. 1989; 264: 1405–13
   PubMed Web of Science ®Google Scholar
• Kessels G.C.R., Gervaix A., Lew P.D., Verhoeven A.J. The chymotrypsin inhibitor carbobenzyloxy-leucinetyro-sine-chloromethylketone interferes with phospholipase D activation induced by formyl-methionyl-leucyl-phenylalanine in human neutrophils. J. Biol. Chem. 1991; 266: 15870–75
   PubMed Web of Science ®Google Scholar
• Agwu D.E., McCall C.E., McPhail I.C. Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils. J. Immunol. 1991; 146: 3895–903
   PubMed Web of Science ®Google Scholar
• Tyagi S.R., Olson S.C., Burnham D.N., Lambeth J.D. Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation. J. Biol. Chem. 1991; 266: 3498–3504
   PubMed Web of Science ®Google Scholar
• Stenke L., Samuelsson J., Palmblad Dabrowski J., Reinzenstein L.P., Lindgren J. Å. Elevated white blood cell synthesis of leukotriene C4 in chronic myelogenous lekamia but not in polycythaemia vera. Br. J. Haematol. 1900; 74: 257–63
   Web of Science ®Google Scholar
• Prchal J.F., Axelrad A.A. Bone–marrow responses in polycythemia vera. N. Eng. J. Med. 1974; 290: 1382
   PubMed Web of Science ®Google Scholar
• Means, Jr., Krantz K. T. S. B., Sawyer S.T., Gilbert H.S. Erythropoietin receptors in polyeythemia vera. J. Clin. Invest. 1989; 84: 1340–44
   PubMed Web of Science ®Google Scholar
• de Wolf Th J.M., Hendriks D.W., Esselink M.T., Halie M.R., Vellenga E. The effects of IL-I and IL-4 in the Epo-independent crythroid progenitor in polycytaemia vera. Br. J. Haematol. 1904; 88: 242–46
   Google Scholar
• de Wolf Beentjes J Th.M., Esselink J.A.M., Smit M. T. J. W., Halie R.M., Clark S.C., Vellenga E. In polyeythemia Vera human interleukin 3 and granulocyte-macrophage colony-stimulating factor enhance erythroid growth in the absence of erythropoietin. Exp. Hematol. 1989; 17: 981–83
   PubMed Web of Science ®Google Scholar
• Dai C.H., Krantz S.B., Means R.T., Jr., Horn S.T., Gilbert H. Polycythemia Vera blood burst-forming units-erythroid are hypersensitive to interleukin-3. J. Clin. Invest. 1991; 87: 391–96
   PubMed Web of Science ®Google Scholar
• Dai C.H., Krantz S.B., Dessypris E.N., Means R.T., Jr., Horn S.T., Gilbert H.S. Polycythemia vera. II. Hypersensitivity of bone marrow erythroid. granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor. Blood 1992; 80: 891–99
   PubMed Web of Science ®Google Scholar
• Correa P.N., Eskinazi D., Axelrad A.A. Circulating erythroid progenitors are hypersensitive to insulin-like growth factor-I in vitro: Studies in an improved serum-free medium. Blood 1994; 83: 99–112
   PubMed Web of Science ®Google Scholar
• Olsson I., Gullberg U., Lantz M., Richter J. The receptors for regulatory molecules of hematopoiesis. Eur. J. Hematol. 1992; 48: 1–9
   PubMed Web of Science ®Google Scholar
• Miyajima A., Mui A.L.F., Ogorochi T., Sakamaki K. Receptors for granulocyte-macrophage colony stimulating factor. interleukin-3 and interleukin-5. Blood 1993; 82: 1960–74
   PubMed Web of Science ®Google Scholar
• Longmore G.D., Watowich S.S., Hilton D.J., Lodish H.F. The erytropoietin receptor: Its role in hematopoiesis and myeloproliferative diseases. J. Cell. Biol. 1993; 123: 1305–8
   PubMed Web of Science ®Google Scholar
• Le Blanc K., Berg A., Palmblad J., Samuelsson J. Stimulus-specific defect in platelet aggregation in polycythemia Vera. Eur. J. Haematol. 1994; 53: 145–49
   PubMed Web of Science ®Google Scholar
• Mora P.A., Valle J., Salvade A., Wright D.G. Inhibition of bone marrow myeloid precursor cell proliferation by chemotactic oligopeptides. Blood 1982; 59: 185–87
   PubMed Web of Science ®Google Scholar
• Meagher R.C., Salvado A.J., Wright D.G. An analysis of multilineage production of human progenitors in long-term bone marrow cultures: evidence that reactive oxygen intermediates derived from mature phagocytic cells have a role in limiting progenitor self-renewal. Blood. 1988; 72: 273–81
   PubMed Web of Science ®Google Scholar
• Lowe G.M., Dang Y., Watson F., Edwards S.W., Galvani D.W. Identification of a subgroup of myelodysplastic patients with a neutrophil stimulation-signalling defect. Br. J. Haematol. 1994; 86: 761–66
   PubMed Web of Science ®Google Scholar
• Kanfer J.N., Hattori H., Orihel D. Reduced phospho-lipase D activity in brain tissue samples from Alzheimer's disease patients. Ann. Neurol. 1986; 20: 265–67
   PubMed Web of Science ®Google Scholar
• Moolenaar W.H., Kruijer W., Tilly B.C., Verlaan I., Bierman A.J., De Last S.W. Growth factor-like action of phosphatidic acid. Nature 1986; 323: 171–173
   PubMed Web of Science ®Google Scholar
• Zhang H., Desai N.N., Murphey J.M., Spiegel S. Increases in phosphatidic acid levels accompany sphingosine-stimulated proliferation of quiescent Swiss 3T3 cells. J. Biol. Chem. 1990; 265: 21309–21316
   PubMed Web of Science ®Google Scholar
• Tsai M.H., Yu C.L., Wei F.S., Stacey D.W. The effects of GTPase activating protein upon ras is inhibited by mitogenically responsive lipids. Science 1989; 243: 522–526
   PubMed Web of Science ®Google Scholar
• Worthen G.S., Avdi N., Buhl A.M., Suzuki N., Johnson G.L. FMLP activates ras and raf in human neutrophils. Potential role in activation of MAP kinase. J. Clin. Invest. 1994; 94: 815–23
   PubMed Web of Science ®Google Scholar
• Stankova L., Rola-Pleszczynski M. Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-I binding activity in human monocytes. Biochem J. 1992; 282: 625–29
   PubMed Web of Science ®Google Scholar