Analysis of MDR1 and MDR3 Multidrug Resistance Gene Expression and Amplification in Consecutive Samples in Patients with Acute Lebkaemias

References

• Juliano R.L., Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta. 1976; 455: 152–162
   PubMed Web of Science ®Google Scholar
• Holmes J.A., West R.R. The effect of MDR-I gene expression on outcome in acute myeloblastic leukaemia Br. J. Cancer 1994; 69: 382–384
   Web of Science ®Google Scholar
• Van der Bliek A.M., Koolman P.M., Schneider C., Borst P. Sequence of mdr3 cDN A encoding a human P-glycoprotein. Gene 1988; 71: 401–411
   PubMed Web of Science ®Google Scholar
• Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162: 156–159
   PubMed Web of Science ®Google Scholar
• Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory manual2nd Edition. Cold Spring Harbour Laboratory Press., New York 1989
   Google Scholar
• Shen D.W., Fojo A., Chin J.E., Roninson I.B., Richert N., Pastan I., Gottesman M.M. Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification. Science 1986; 232: 643–645
   PubMed Web of Science ®Google Scholar
• Bennett J.M., Catovsky D., Daniel M-T., Flandrin G., Galton D.A.G., Gralnick H.R., Sultan C. Proposals for the classification of the acute leukaemias. Br. J. Haematol. 1976; 33: 451–458
   PubMed Web of Science ®Google Scholar
• Brophy N.A., Marie J.P., Rojas V.A., Warnke McFall R.A., Smith S. D P.J., Sikic B.I. Mdr1 gene expression in childhood acute lymphoblastic leukaemias and lymphomas: A critical evaluation by four techniques. Leukaemia 1994; 8: 327–335
   PubMed Web of Science ®Google Scholar
• Lyttelton M.P.A., Hart S., Ganeshaguru K., Prentice H.G., Hoffbrand A.V., Mehta A.B. Multidrug resistance in acute leukaemia: A comparative study of immunocytochemical and RNA slot blot detection of P-glycoprotein expression. Leukaemia and Lymphoma 1991; 5: 357–364
   PubMed Web of Science ®Google Scholar
• Gruber A., Vitols S., Norgren S., Arestrom I., Peterson C., Bjorkholm M., Reizenstein P., Luthman H. Quantitative determination of mdr1 gene expression in leukaemic cells from patients with acute leukaemia. Br. J. Cancer. 1992; 66: 266–272
   PubMed Web of Science ®Google Scholar
• Pieters R., Hongo T., Loonen A.H., Huismans D.R., Broxterman H.J., Hahlen K., Veerman A.J.P. Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukaemia. Brit, J. Cancer. 1992; 65: 691–697
   PubMed Web of Science ®Google Scholar
• Pieters R., Kaspers G.J.L., Klumper E., Veerman A.J.P. Clinical relevance of in vitro drug resistance testing in childhood acute lymphoblastic leukaemia: The state of the art. Pediatric Oncol. 1994; 22: 299–308
   PubMedGoogle Scholar
• Gekeler V., Frese G., Noller A., Handgretinger R., Wilisch A., Schmidt H., Muller C.P., Dopfer R., Klingebiel T., Diddens H., Probst H., Niethammer D. MDR IP-glycoprotein, topoisomerase, and glutathione-S-transferase Pi gene expression in primary and relapsed state adult and childhood leukaemias. Br. J. Cancer 1992; 66: 507–517
   PubMed Web of Science ®Google Scholar
• Ito Y., Tanimoto M., Kumazawa T., Okumura M., Morishima Y., OhNo R., Saito H. Increased P-glycoprotein expression and multidrug-resistant gene (mdr1) amplification are infrequently found in fresh acute leukaemia cells. Cancer 1989; 63: 1534–1538
   PubMed Web of Science ®Google Scholar
• Sato H., Preisler H., Day R., Raza A., Larson R., Browman G., Goldberg J., Vogler R., Grunwald H., Gottlieb A., Bennett J., Gottesman M.M., Pastan I. MDRI transcript levels as an indicator of resistant disease in acute myelogenous luekemiia. Br. J. Haematol. 1990; 75: 340–345
   PubMed Web of Science ®Google Scholar
• Pirker R., Wallner J., Geissler K., Linkesch W., Haas O.A., Bettlleheim P., Hopfner M., Schemer R., Valent P., Havelec L., Ludwig H., Lechner K. MDRI gene expression and treatment outcome in acute myeloid leukaemia. J. Natl. Cancer Inst. 1991; 83: 708–712
   PubMed Web of Science ®Google Scholar
• Marie J.P., Zittoun R., Sikic B.I. Multidrug resistance (mdr1) gene expression in adult acute leukaemias: correlations with treatment outcome and in vitro drug sensitivity. Blond. 1991; 78: 586–592
   PubMed Web of Science ®Google Scholar
• Kuwazuru Y., Yoshimura A., Hanada S., Utsunomiya A., Makino T., Ishibashi K., Kodama M., Iwahashi M., Arima T., Akiyama S-I. Expression of the multidrug transporter, P-glycoprotein. in acute leukaemia cells and correlation to clinical drug resistance. Cancer. 1990; 66: 868–873
   PubMed Web of Science ®Google Scholar
• Nooter K., Sonneveld P. Clinical relevance of P-glycoprotein expression in haematological malignancies. Leukaemia Res. 1994; 18: 233–243
   PubMed Web of Science ®Google Scholar
• Chan H.S.L., De Boer G., Thorner P.S., Haddad G., Gallie B.L., Ling V. Multidrug resistance: Clinical opportunities in diagnosis and circumvention. Hematology/Oncology clinics of North America. 1994; 8: 383–410
   PubMed Web of Science ®Google Scholar
• Noonan K.E., Beck C., Holzmayer TG.A., Chin J.E., Wunder J.S., Andrulis I.L., Gazdar A.F., Willman C.L., Von Griffith B., Hoff D.D., Roninson I. Quantitative analysis of MDRI multidrug resistance gene expression in human tumors by polymerase chain reaction. Proc. Natl. Acad. Sci. USA 1990; 87: 7160–7164
   PubMed Web of Science ®Google Scholar
• Drach D., Drach J., Mahdevia R., Gattringer C., Huber H., Andreeff M. Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistance phenotype. Blood. 1992; 80: 2729–2734
   PubMed Web of Science ®Google Scholar
• Zastawny R.L., Salvino R., Chem J., Benchimol S., Ling V. The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. Oncogene 1993; 8: 1529–1535
   PubMed Web of Science ®Google Scholar
• Dittmer D., Pati S., Zambetti G., Chu S., Teresky A.K., Moore M., Finlay C., Levine A.J. Gain of function mutations in p53. Nature Generics 1993; 4: 42–46
   PubMed Web of Science ®Google Scholar
• Herweijer H., Sonneveld P., Baas F., Nooter K. Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukaemias and association with stimulation of drug accumulation by cyclosporin. J. Natl. Cancer Inst. 1990; 82: 1133–1140
   PubMed Web of Science ®Google Scholar
• Baines P., Cumber P., Padua R.A. Multidrug resistance in leukaemia. Bailliere's Clinical Haematology 1992; 5: 943–060
   PubMed Web of Science ®Google Scholar
• Lyttelton M.P.A., Hart S., Ganeshaguru K., Hoffbrand A.V., Mehta A.B. Quantitation of multidrug resistant MDR1 transcript in acute myeloid leukaemia by non-isotopic quantitative cDNA polymerase chain reaction. Br. J. Haematol. 1994; 86: 540–546
   PubMed Web of Science ®Google Scholar