The Involvement of the Candidate Proto-Oncogene NFKB2/lyt-10 in Lymphoid Malignancies

References

• Mitchell P. J., Tjian R. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 1989; 245: 371–378
   PubMed Web of Science ®Google Scholar
• Bishop M. J. Molecular themes in oncogenesis. Cell 1991; 64: 235–248
   PubMed Web of Science ®Google Scholar
• Geary M. L. Oncogenic conversion of transcription factors by chromosomal translocations. Cell 1991; 66: 619–622
   PubMed Web of Science ®Google Scholar
• Rabbitts T. H. Translocations, master genes, and differences between the origins of acute and chronic leukemias. Cell 1991; 67: 641–644
   PubMed Web of Science ®Google Scholar
• Nichols J., Nimer S. D. Transcription factors, translocations, and leukemia. Blood 1992; 80: 2953–2963
   PubMed Web of Science ®Google Scholar
• Grilli M. G., Chiu J. J-S., Lenardo M. J. NF-κB and Rel: Partecipants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 1991; 143: 1–61
   Web of Science ®Google Scholar
• Baeuerle P. M., Henkel T. Function and activation of the NF-κB in the immune system. Ann. Rev. Immunol. 1994; 12: 141–179
   PubMed Web of Science ®Google Scholar
• Liou H-C., Sha W. C., Scott M. L., Baltimore D. Sequential induction of the NF-κB/Rel family proteins during B-cell terminal differentiation. Mol. Cell. Biol. 1994; 14: 5349–5359
   PubMed Web of Science ®Google Scholar
• Weih F., Carrasco D., Bravo R. Constitutive and inducible Rel/NF-KB activities in mouse thymus and spleen. Oncogene 1995; 9: 3289–3297
   Web of Science ®Google Scholar
• Sha W. C., Liou H-C., Tuomanen E. I., Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 1995; 80: 321–330
   PubMed Web of Science ®Google Scholar
• Weih F., Carrasco D., Durham S. K., Barton D. S., Rizzo C. A., Ryseck R-P., Lira S. A., Bravo R. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/rel family. Cell 1995; 80: 331–340
   PubMed Web of Science ®Google Scholar
• Wilhelmsen K. C., Eggleton K., Temin H. M. Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c- rel. J. Virol. 1984; 52: 172–182
   PubMed Web of Science ®Google Scholar
• Nolan G., Ghosh S., Liou H. C., Tempst P., Baltimore D. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell 1991; 64: 961–969
   PubMed Web of Science ®Google Scholar
• Ryseck R-P., Bull P., Takamiya M., Bours V., Siebenlist U., Dobrzanski P., Bravo R. RelB, a new Rel family transcription activator that can interact with p50-NF-κB. 1992
   Google Scholar
• Kieran M., Blank V., Logeat F., Vandekerckhove J., Lottespeich F., Le Bail O., Urban M. B., Kourilsky P., Baeuerle P. A., Israel A. The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 1990; 62: 1007–1018
   PubMed Web of Science ®Google Scholar
• Ghosh S., Gifford A. M., Riviere L. R., Tempst P., Nolan G. P., Baltimore D. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 1990; 62: 1019–1029
   PubMed Web of Science ®Google Scholar
• Schmid R. M., Perkins N. D., Duckett C. S., Andrews P. C., Nabel G. J. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature 1991; 352: 733–736
   PubMed Web of Science ®Google Scholar
• Neri A., Chang C-C., Lombardi L., Salina M., Corradini P., Maiolo A. T., Chaganti R. S. K., Dalla-Favera R. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κBp50. Cell 1991; 67: 1075–1087
   PubMed Web of Science ®Google Scholar
• Bours V., Burd P. R., Brown K., Villalobos J., Park P., Ryseck R. P., Bravo R., Kelly K., Siebenlist U. A novel mitogen-inducible gene product related to p50/p105-NF-κB partecipates in transactivation through a κB site. Mol. Cell. Biol. 1992; 12: 685–695
   PubMed Web of Science ®Google Scholar
• Lux S. E., John K. M., Bennett V. Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle proteins. Nature 1990; 344: 36–42
   PubMed Web of Science ®Google Scholar
• Mercurio F., Didonato J. A., Rosette C., Karin M. p 105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction. Gene. & Dev. 1993; 7: 705–718
   PubMed Web of Science ®Google Scholar
• Chang C-C., Zhang J., Lombardi L., Neri A., Dalla-Favera R. Mechanism of expression and role in transcriptional control of the proto-oncogene NFKB2/LYT-10. Oncogene 1994; 9: 923–933
   PubMed Web of Science ®Google Scholar
• Gilmore T., Morin P. The IκB proteins: members of a multifunctional family. Trends Genet. 1993; 9: 427–433
   PubMed Web of Science ®Google Scholar
• Thompson J. E., Phillips R. J., Redjument-Bromage H., Tempst P., Ghosh S. IκB-β regulates the persistent response in a biphasic activation of NF-KB. Cell 1995; 80: 573–582
   PubMed Web of Science ®Google Scholar
• Ohno H., Takimoto G., McKeitan T. W. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell 1990; 60: 991–997
   PubMed Web of Science ®Google Scholar
• Zhang Q., Didonato J. A., Karin M., McKeitan T. W. Bcl-3 encodes a nuclear protein which can alter the subcellular location of NF-κB proteins. Mol. Cell. Biol. 1994; 14: 3915–3926
   PubMed Web of Science ®Google Scholar
• Ten R. M., Paya C. V., Israel N., Le Bail O., Mattel M. G., Virelizier J. L., Kourilsky M., Israel A. The characterization of the promoter of the gene encoding the p50 subunit of the NF-κB indicates that it partecipates in its own regulation. EMBO J. 1992; 11: 195–203
   PubMed Web of Science ®Google Scholar
• Le Bail O., Schmidt-Ullrich R., Israel A. Promoter analysis of the gene encoding the Ikβα/Mad3 inhibitor of the NF-κB: positive regulation by members of the rel/NF-κB family. EMBO J. 1993; 12: 5043–5049
   PubMed Web of Science ®Google Scholar
• Lombardi L., Ciana P., Cappellini C., Trecca D., Guerrini L., Migliazza A., Maiolo A. T., Neri A. Structural and functional characterization of the promoter regions of the NFKB2 gene. Nucleic Acid Res. 1995; 23: 2328–2336
   PubMed Web of Science ®Google Scholar
• Fracchiolla N. S., Lombardi L., Salina M., Migliazza A., Baldini L., Berti L., Cro E., Polli E., Maiolo A. T., Neri A. Structural alterations of the NF-κB transcription factor lyt-10 in lymphoid malignancies. Oncogene 1993; 8: 2839–2845
   PubMed Web of Science ®Google Scholar
• Neri A., Fracchiolla N. S., Roscetti E., Garatti S., Trecca D., Boletini A., Perletti L., Baldini L., Maiolo A. T., Neri A. Molecular analysis of cutaneous B- and T-cell lymphomas. Blood 1995; 86: 3160–3172
   PubMed Web of Science ®Google Scholar
• Thakur S., Lin J-C., Tseng W-T., Kumar S., Bravo R., Foss F., Gelinas C., Rabson A. B. Rearrangement and altered expression of the NFKB2 gene in human cutaneous T-lymphoma cells. Oncogene 1994; 9: 2335–2344
   PubMed Web of Science ®Google Scholar
• Zhang J., Chang C-C., Lombardi L., Dalla-Favera R. Rearranged NFKB2 gene in HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions. Oncogene 1994; 10: 1931–1937
   Google Scholar
• Migliazza A., Lombardi L., Rocchi M., Trecca D., Chang C-C., Antonacci R., Fracchiolla N. S., Ciana P., Maiolo A. T., Neri A. Heterogeneous chromosomal aberrations generate 3' truncations of the NFKB2/lyt-10 gene in lymphoid malignancies. Blood 1994; 84: 3850–3860
   PubMed Web of Science ®Google Scholar
• Marcu K. B., Lang R. B., Stanton L. W., Harris L. A model for the molecular requirements of immunonoglobulin heavy chain class switching. Nature 1982; 298: 87–90
   PubMed Web of Science ®Google Scholar
• Chang C-C., Zhang J., Lombardi L., Neri A., Dalla-Favera R. Rearranged NFKB2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators. Mol. Cell. Biol. 1995; 15: 5180–5187
   PubMed Web of Science ®Google Scholar
• Matthew S., Murty V. V. V. S., Dalla-Favera R., Chaganti R. S. K. Chromosomal localization of the genes encoding the transcription factors c-rel NF-κBp50, NF-κBp65, and lyt-10 by fluorescence in situ hybridization. Oncogene 1993; 8: 191–193
   PubMed Web of Science ®Google Scholar
• Lu D., Thompson J. D., Gorski G. K., Rice N. R., Mayer M. G., Yunis J. J. Alterations of the rel locus in human lymphoma. Oncogene 1991; 6: 1235–1241
   PubMed Web of Science ®Google Scholar