52
Views
33
CrossRef citations to date
0
Altmetric
Original Article

Nuclear NF-ATp is a Hallmark of Unstimulated B Cells from B-CLL Patients

, , , &
Pages 583-592 | Received 17 Mar 1996, Published online: 01 Jul 2009

References

  • Faguet G. B. Chronic lymphocytic leukemia: an updated review. J. Clin. Oncol. 1994; 12: 1974–1990
  • Geisler C. H., Larsen J. K., Hansen N. E., Hansen M. M., Christensen B. E., Lund B., Nielsen H., Plesner T., Thorling K., Andersen E., Andersen P. K. Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with B-cell chronic lymphocytic leukemia. Blood 1991; 78: 1795–1802
  • Delespesse G., Sarfati M., Wu C. Y., Fournier S., Letellier M. The low-affinity receptor for IgE. Immunol. Rev. 1992; 125: 77–97
  • Barclay A. N., Birkeland M. L., Brown M. H., Beyers A. D., Davis S. J., Somoza C., Williams A. F. The Leucocyte Antigen Facts Book. Academic Press. Harcourt Brace Jovanovich, Publishers, London, San Diego, New York, Boston, Sydney, Tokyo, Toronto 1993
  • Juliusson G., Gahrton G. Chromosome aberrations in B cell chronic lymphocytic leukemia. Pathogenetic and clinical implications. Cancer Genet. Cytogenet. 1990; 45: 143–160
  • Liu Y., Grander D., SÖDerhall S., Juliusson G., Gharton G., Einhorn S. Retinoblastoma gene deletions in B-cell chronic lymphocytic leukemias. Genes, Chrom. Cancer 1992; 4: 250–256
  • Korsmeyer S. J. Chromosomal Translocations in Lymphoid Malignancies reveal novel Proto-Oncogenes. Annu. Rev. Immunol. 1992; 10: 785–807
  • Ohno H., Takimoto G., McKeithan T. W. The Candidate Proto-Oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell 1990; 60: 991–997
  • Lo Coco F., Ye B. H., Lista F., Corradini P., Offit K., Knowles D. M., Chaganti R. S. K., Dalla-Favera R. Rearrangements of the BCL6 gene in diffuse large cell Non-Hodgkin's lymphomas. Blood 1994; 83: 1757–1759
  • Hatano M., Roberts C. W. M., Minden M., Crist W. M., Korsmeyer S. J. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 1991; 253: 79–82
  • Kennedy M. A., Gonzalez-Sarmiento R., Kees U. R., Lampert F., Dear N., Boehm T., Rabbitts T. H. HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24. Proc. Natl. Acad. Sci. USA 1991; 88: 8900–8904
  • Angel P., Herrlich P. The FOS and JUN Families of Transcription Factors. CRC Press, Boc Raton, Ann Arbor, London and Tokyo 1994
  • Bose H. R. The Rel family: models for transcriptional regulation and oncogenic transformation. Biochim. Biophys. Acta. 1992; 1114: 1–17
  • Rao A. NF-ATp: a transcriptional factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 1994; 15: 274–281
  • Serfling E., Avots A., Neumann M. The architecture of the Interleukin-2 promoter: a reflection of T lymphocyte activation. Biochim. Biophys. Acta 1995; 1263: 181–200
  • Liu T. FK506 and cyclosporin, molecular probes for studying intracellular signal transduction. Immunol. Today 1993; 14: 290–295
  • Choi M. S. K., Brine R. D., Holman M. J., Klaus G. G. B. Induction of NF-AT in normal B lymphocytes by antiimmunoglobulin or CD40 ligand in conjunction with IL-4. Immunity 1994; 1: 179–187
  • Venkataraman L., Francis D. A., Wang Z., Liu J., Rothstein T. L., Sen R. Cyclosporin-A sensitive induction of NF-AT in murine B cells. Immunity 1994; 1: 189–196
  • Marti G. E., Fleischer T. A. B Cell CLL Immunophenotypes in Chronic Lymphocytic Leukemia: Recent Progress and Future Directions, R. Gale, K. Rai. Alan R. Liss, Inc., New York 1987
  • Callard R. E. Human B cell responses to cytokines. Cytokines. A Practical Approach, F. R. Balkwill. IRL Press, Oxford, New York and Tokyo 1991; 121–150
  • Schreiber E., Matthias P., MÜLler M. M., Schaffner W. Rapid detection of octamer binding proteins with ‘mini-extracts’, prepared from a small number of cells. Nucl. Acids Res. 1989; 17: 6419
  • Neumann M., Tsapos K., Scheppler J. A., Ross J., Franza B. R. Identification of complex formation between two intracellular tyrosine kinase substrates: human c-Rel and the p105 precursor of o50 NF-kB. Oncogene 1992; 7: 2095–2104
  • Wirth T., Priess A., Annweiler A., Zwilling S., Oeler B. Multiple Oct2 isoforms are generated by alternative splicing. Nucl. Acids Res. 1991; 19: 43–51
  • McCaffrey P. G., Luo C., Kerppola T. K., Jain J., Badalian T. M., Ho A. M., Burgeon E., Lane W. S., Lambert J. N., Curran T., Verdine G. L., Rao A., Hogan P. G. Isolation of the Cyclosporin-sensitive T cell transcription factor NF-ATp. Science 1993; 262: 750–754
  • Randak C., Brabletz T., HergenrÖTher M., Sobotta I., Serfling E. Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer. Embo J. 1990; 9: 2529–2536
  • Briegel K., Hentsch B., Pfeuffer I., Serfling E. One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter. Nucl. Acids Res. 1991; 19: 5929–5936
  • Schreiber E., Matthias P., MÜLler M. M., Schaffner W. Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic bandshift assay (PCBA). Embo J. 1988; 7: 4221–4229
  • Liou H.-C., Sha W. C., Scott M. L., Baltimore D. Sequential induction of NF-kB/Rel family proteins during B-cell terminal differentiation. Mol. Cell. Biol. 1994; 14: 5349–5359
  • Hoey T., Sun Y.-L., Xu X. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 1995; 2: 461–472
  • June C. H., Rabinovitch P. S., Ledbetter J. A. CD5 antibodies increase intracellular ionized calcium concentration in T cells. J. Immunol. 1987; 138: 2782–2792
  • Raab M., Yamamoto M., Rudd C. E. The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p561ck. Mol. Cell. Biol. 1994; 14: 2862–2870
  • Straus D. B., Weiss A. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 1992; 70: 585–593
  • Neri A., Chang C.-C., Lombardi L., Salina M., Corradini P., Maiolo A. T., Chaganti R. S. K., Dalla-Favera R. B Cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kB p50. Cell 1991; 67: 1075–1087
  • Fracchiolla N. S., Lombardi L., Salina M., Migliazza A., Baldini L., Berti E., Cro L., Polli E., Maiolo A. T., Neri A. Structural alterations of the NF-kB transcription factor lyt-10 in lymphoid malignancies. Oncogene 1993; 8: 2839–2845
  • Bours V., Franzoso G., Azarenko V., Park S., Kanno T., Brown K., Siebenlist U. The oncoprotein Bcl-3 directly trans-activates through kB motifs via association with DNA-binding p50B homodimers. Cell 1993; 72: 729–739
  • Baeuerle P. A., Henkel T. Function and activation of NF-kB in the immune system. Annu. Rev. Immunol. 1994; 12: 141–179
  • Tycko B., Smith S. D., Sklar J. Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia. J. Exp. Med. 1991; 174: 867–873
  • Migone T.-S., Lin J.-X., Cereseto A., Mulloy J. C., O'Shea J. J., Franchini G., Leonard W. J. Constitutively activated Jak-STAT pathway in T cell transformed with HTLV-I. Science 1995; 269: 79–81

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.