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Original Article

The Comparison of 2-Chlorodeoxyadenosine (2-Cd A) in Combination with Interferon α (IFN α) or Interferon γ (IFN γ) on Granulocyte-Macrophage Progenitor Cells (CFU-GM) and Clonogenic Blasts in (CFU-L) In Vitro Cultures

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Pages 161-168 | Received 08 Jun 1995, Published online: 01 Jul 2009

References

  • Piro L. D. 2-chlorodeoxyadenosine treatment of lymphoid malignancies. Blood 1992; 80: 843–845
  • Lauria F. 2-Chlorodeoxyadenosine, “novel” agent in the treatment of both lymphoid and myeloid malignancies. Haematologica 1992; 77: 443–445
  • Santana V. M., Mirro J., Kearns C., Schell M. J., Crom W. Chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia. J. Clin. Oncol 1992; 10: 364–370
  • Saven A., Lemon R., Figueroa M., Kosty M., Ellison D. Complete hematologic remissions in stable phase. Ph–chromosome positive, chronic myeloid leukemia (CML) following 2-chlorodeoxyadenosine (2-CdA). Proc. Am. Soc. Clin. Oncol 1993; 310, (Abst. No 1022)
  • Goldstein D., Laszlo J. Interferon in cancer: From imagination to inrferon. Cancer Res 1986; 46: 4315–4329
  • Wadler S., Schwartz E. L. Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies. A review. Cancer Res 1990; 50: 3473–3486
  • Dvilansky A., Kafka M., Nathan J. Mechanisms of interaction between interferon gamma and antineoplastic agents on growth and differentiation of leukemic cells: a review. Leuk. Lymph 1992; 6: 469–477
  • Robak T., Korycka A., Góra-Tybor J. The interaction of 2-chlorodeoxydenosine (2-CdA) and interferon α (IFNα) on normal and myeloid leukemia hematopoiesis in vitro. Leuk. Res 1994; 18: 275–281
  • Iscove N. N., Sieber F., Winterhalter K. H. Erythroid colony formation in culture of mouse and human bone marrow. Analysis of the requirement chromatography on agarose-cancanavalin A. Am. J. Cell. Physiol 1974; 83: 303–320
  • Hibbin J. A., Nioku O. S., Matutes E., Lewis S. M., Goldman J. M. Myeloid progenitor cells in the circulation of patients with myelofibrosis and other myeloproliferative disorders. Br. J. Haematol 1984; 57: 495–503
  • Buick R. N., Till J. E., McCulloch E. A. Colony assay for proliferative blast cells circulation in myeloid leukemia. Lancet 1977; 1: 862–863
  • Korycka A., Robak T. The effect of lithium chloride on granulocyte-macrophage progenitor cells (CFU-GM) and clonogenic leukemic blasts (CFU-L) in the cultures in vitro. Arch. Immunol. Ther. Exp 1991; 39: 495–500
  • Minden M. D., Buick R. N., McCulloch E. A. Separation of blast cells and T-lymphocyte progenitors in the blood of patients with acute myeloid leukemia. Blood 1979; 54: 186–195
  • Kazimierczuk Z., Vilpo J., Hildebrand C., Wright G. Synthesis and cytotoxicity of deoxyadenosine analogues: isomer distribution in the sodium salt glycosylation of 2,6-disubstitutes purines. J. Med. Chem 1990; 33: 1683–1687
  • Kristensen J., Nygren P., Liliemark J., Fridborg H., Kiliander A., Simonsson B., Oberg G., Larsson R. Interactions between Cladribine (2-CdA) and standard antileukemic drugs in primary cultures of human tumor cells from patients with acute myeloid leukemia. Leukemia 1994; 8: 1712–1717
  • Kurzrock R., Talpaz M., Kantarjian H., Walters R., Saks S., Trujillo J. M., Gutterman J. U. Therapy of chronic myeloid leukemia with recombinant interferon-γ. Blood 1987; 70: 943–947
  • Mahmoud H. H., Pui G. H., Kennedy W., Saffe H. S., Crist W. M., Murphy S. B. Phase I study of recombinant human interferon gamma in children with relapsed acute leukemia. Leukemia 1992; 6: 1181–1184
  • Petzer A. L., Bilgeri R., Zihan U., Hann M., Geisen F. H., Pragnell J., Bransteiner H., Konwalinka G. Inhibitory effect of 2-chlorodeoxyadenosine on granulocytic, erythroid and T-lymphocytic colony growth. Blood 1991; 78: 2583–2587
  • Bryson H. M., Sorkin E. M. Cladribine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in hematological malignancies. Drugs 1993; 46: 872–894
  • Nara N. Combined effect of interferon-γ and tumor necrosis factor-α causing suppression of leukemic blast progenitors in acute myeloid leukemia. Leuk. Lymph 1993; 10: 201–207
  • Koike K., Ma F., Shiohara M., Kubo T., Takagi M., Amano Y., Nakahata T., Komiyama A. Interferon gamma inhibits proliferation but not commitment of murine graulocyte-macrophage progenitors. J. Cell. Physiol 1992; 153: 528–533
  • Shiohara M., Koike K., Nakahata T. Synergism of interferon-γ and stem cell factor on the development of murine hematopoietic progenitors in serum free culture. Blood 1993; 81: 1435–1441
  • Mamus S. W., Beck-Schroder S., Zanjani E. D. Suppression of normal human erythropoiesis by gamma interferon in vitro. Role of monocytes and T-lymphocytes. J. Clin. Invest 1985; 75: 1496–1503
  • Delforge A., Vandenplas B., Lagneaux L., Loos M., Bron D., Debusscher L., Strykmans P. Influence of recombinant alpha and gamma interferons on the in vitro proliferation of myeloid leukemic progenitors. Eur. J. Haematol 1990; 44: 307–311
  • Todd P. A., Goa K. L. Interferon-γ-lb. A review of its pharmacology and therapeutic potential in chronic granulomatous disease. Drugs 1992; 43: 111–122
  • Morikawa K., Fan D., Denkins Y. M., Lewis B., Gutterman J. U., Walker S. M., Fidler I. J. Mechanism of combined effects of γ-interferon and 5-fluorouracil on human colon cancer implanted into nude mice. Cancer Res 1989; 49: 799–805
  • Lienard D., Ewalenko P., Delmotte J. J., Renard N., Lejeune F. J. High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of limbs melanoma and sarcoma. J. Clin. Oncol 1992; 10: 52–60
  • Kafka M., Nathan J., Dvilansky A. New combination of 5-Fluorouracil and interferon-γ effective against human myeloid leukemia in vitro. Anticancer Res 1989; 9: 1037–1040
  • Kafka M., Dvilansky A., Nathan J. Mechanism of interaction between interferon-γ and antineoplastic agents on the differentiation of HL-60 promyelocyte cells. Exp. Hematol 1990; 18: 153–158
  • Robertson L. E., Chubb S., Meyn R. E., Stoy M., Ford R., Hittelman W. N., Plunket W. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'deoxyadenosine and 9–D-arabinosyl-2-fluoroadenine. Blood 1993; 81: 143–150
  • Faltynek C. R. Opposite effects of recombinant interferon-α and deoxycoformycin on adenosine deaminase in the Dandi B lymphoblastoid cell line. Blood 1988; 71: 59–64
  • Carlo-Stella C., Cazzola M., Ganser A., Bergamachi G., Pedrazzoli P., Hoelzer D., Ascari E. Synergistic antiproliferative effect of recombinant interferon-γ with recombinant interferon-α on chronic myelogenous leukemia hematopoietic progenitor cells (CFU-GEMM, CFU-Mk, BFU-E and CFU-E). Blood 1988; 73: 1293–1299
  • Ishii Y., Tsukagoshi S. The synergistic effect of human recombinant interferon alpha 2a in combination with interferon gamma and the induction of interferon alpha 2a receptor by interferon gamma. J. Pharmacobiodyn 1989; 12: 299–304
  • Wandl U. B., Ogalka B., Kloke O., Nagel-Hiemke M., Moritz T., Niederle N. Treatment of chronic myelogenous leukemia with different cytokines. Semin. Oncol 1992; 19: 80–86, (Supp. 4)

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