Genomic DNA Amplification and the Detection of t(2;5)(p23;q35) in Lymphoid Neoplasms

References

• Stein H., Mason D. Y., Gerdes J., O'Connor N., Wainscoat J., Pallesen G., Gatter K., Falini B., Delsol G., Lemke H., Schwarting R., Lennert K. The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 1985; 66: 848–58
   PubMed Web of Science ®Google Scholar
• Stansfeld A. G., Diebold J., Noel H., Kapanci Y., Rilke F., Kelenyi G., Sundstrom C., Lennert K., Vanunnik J. A. M., Mioduszewska O., Wright D. H. Updated Kiel classification for lymphomas. Lancet 1988; 1: 292–3
   PubMed Web of Science ®Google Scholar
• Harris N. L., Jaffe E. S., Stein H., Banks P. M., Chan J. K., Cleary M. L., Delsol G., De Wolf-Peeters C., Falini B., Gatter K. C., Grogan T. M., Isaacson P. G., Knowles D. M., Mason D. Y., Muller-Hermelink H.-K., Pileri S. A., Piris M. A., Ralfkiaer E., Warnke R. A. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994; 84: 1361–92
   PubMed Web of Science ®Google Scholar
• Greer J. P., Kinney M. C., Collins R. D., Salhany K. E., Wolff S. N., Hainsworth J. D., Flexner J. M., Stein R. S. Clinical features of 31 patients with Ki-1 anaplastic large-cell lymphoma. J Clin Oncol 1991; 9: 539–47
   PubMed Web of Science ®Google Scholar
• Chott A., Kaserer K., Augustin I., Vesely M., Heinz R., Oehlinger W., Hanak H., Radaszkiewicz T. Ki-1 positive large cell lymphoma. A clinicopathologic study of 41 cases. Am J Surg Pathol 1990; 14: 439–48
   PubMed Web of Science ®Google Scholar
• Chan J. K., Ng C. S., Hui P. K., Leung T. W., Lo E. S., Lau W. H., McGuire L. J. Anaplastic large cell Ki-1 lymphoma. Delineation of two morphological types. Histopathology 1989; 15: 11–34
   PubMed Web of Science ®Google Scholar
• Kinney M. C., Collins R. D., Greer J. P., Whitlock J. A., Sioutos N., Kadin M. E. A small-cell-predominant variant of primary Ki-1 (CD30)+ T-cell lymphoma. Am J Surg Pathol 1993; 17: 859–68
   PubMed Web of Science ®Google Scholar
• Pileri S., Falini B., Delsol G., Stein H., Baglioni P., Poggi S., Martelli M. F., Rivano M. T., Mason D. Y., Stansfeld A. G. Lymphohistiocytic T-cell lymphoma (anaplastic large cell lymphoma CD30+/Ki-1+ with a high content of reactive histiocytes). Histopathology 1990; 16: 383–91
   PubMed Web of Science ®Google Scholar
• Chan J. K., Buchanan R., Fletcher C. D. Sarcomatoid variant of anaplastic large-cell Ki-1 lymphoma. Am J Surg Pathol 1990; 14: 983–8
   PubMed Web of Science ®Google Scholar
• Kinney M. C., Glick A. D., Stein H., Collins R. D. Comparison of anaplastic large cell Ki-1 lymphomas and microvillous lymphomas in their immunologic and ultra-structural features. Am J Surg Pathol 1990; 14: 1047–60
   PubMed Web of Science ®Google Scholar
• Pileri S., Bocchia M., Baroni C. D., Martelli M., Falini B., Sabattini E., Gherlinzoni F., Amadori S., Poggi S., Mazza P., Burgio V., Zinzani P. L., Melilli G., Benni M., Saragoni L., Martelli M., Stein H., Mandelli F., Tura S. Anaplastic large cell lymphoma (CD30+/Ki-1+): results of a prospective clinico-pathological study of 69 cases. Br J Haematol 1994; 86: 513–23
   PubMed Web of Science ®Google Scholar
• Stein H., Herbst H., Anagnostopoulos I., Niedobitek G., Dallenbach F., Kratzsch H. C. The nature of Hodgkin and Reed-Sternberg cells, their association with EBV, and their relationship to anaplastic large-cell lymphoma. Ann Oncol 1991; 2: 33–8
   PubMed Web of Science ®Google Scholar
• Bitter M. A., Franklin W. A., Larson R. A., McKeithan T. W., Rubin C. M., Le B. M., Stephens J. K., Vardiman J. W. Morphology in Ki-l(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2; 5)(p23; q35). Am J Surg Pathol 1990; 14: 305–16
   PubMed Web of Science ®Google Scholar
• Kaudewitz P., Stein H., Dallenbach F., Eckert F., Bieber K., Burg G., Braun-Falco O. Primary and secondary cutaneous Ki-1+ (CD30+) anaplastic large cell lymphomas. Morphologic, immunohistologic, and clinical-characteristics. Am J Pathol 1989; 135: 359–67
   PubMed Web of Science ®Google Scholar
• Cabanillas F., Armitage J., Pugh W. C., Weisenburger D., Duvic M. Lymphomatoid papulosis: a T-cell dyscrasia with a propensity to transform into malignant lymphoma. Annals of Internal Medicine 1995; 122: 210–217
   PubMed Web of Science ®Google Scholar
• Schwab U., Stein H., Gerdes J., Lemke H., Kirchner H., Schaadt M., Diehl V. Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells. Nature 1982; 299: 65–7
   PubMed Web of Science ®Google Scholar
• Stein H., Dallenbach F. Diffuse large cell lymphomas of B-and T-cell type. Neoplastic Hematopathology, D. M. Knowles. Williams and Wilkins, Baltimore 1992
   Google Scholar
• Durkop H., Latza U., Hummel M., Eitelbach F., Seed B., Stein H. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 1992; 68: 421–7
   PubMed Web of Science ®Google Scholar
• Pinto A., Gloghini A., Gattei V., Aldinucci D., Zagonel V., Carbone A. Expression of the c-kit receptor in human lymphomas is restricted to Hodgkin's disease and CD30+ anaplastic large cell lymphomas. Blood 1994; 83: 785–92
   PubMed Web of Science ®Google Scholar
• Inghirami G., Macri L., Cesarman E., Chadburn A., Zhong J., Knowles D. M. Molecular characterization of CD30+ anaplastic large-cell lymphoma: high frequency of c-myc proto-oncogene activation. Blood 1994; 83: 3581–90
   PubMed Web of Science ®Google Scholar
• Leoncini L., Del Vecchio M. T., Kraft R., Megha T., Barbini P., Cevenini G., Poggi S., Pileri S., Tosi P., Cottier H. Hodgkin's disease and CD30-positive anaplastic large cell lymphomas-a continuous spectrum of malignant disorders. A quantitative morphometric and immunohistologic study. Am J Pathol 1990; 137: 1047–57
   PubMed Web of Science ®Google Scholar
• Davis T. H., Morton C. C., Miller-Cassman R., Balk S. P., Kadin M. E. Hodgkin's disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone. N Engl J Med 1992; 326: 1115–22
   PubMed Web of Science ®Google Scholar
• Le Beau M. M., Bitter M. A., Larson R. A., Doane L. A., Ellis E. D., Franklin W. A., Rubin C. M., Kadin M. E., Vardiman J. W. The t(2; 5)(p23; q35): a recurring chromosomal abnormality in Ki-1-positive anaplastic large cell lymphoma. Leukemia 1989; 3: 866–70
   PubMed Web of Science ®Google Scholar
• Mason D. Y., Bastard C., Rimokh R., Dastugue N., Huret J. L., Kristoffersson U., Magaud J. P., Nezelof C., Tilly H., Vannier J. P., Hemet J., Warnke R. CD30-positive large cell lymphomas (‘Ki-1 lymphoma’) are associated with a chromosomal translocation involving 5q35 [see comments]. Br J Haematol 1990; 74: 161–8
   PubMed Web of Science ®Google Scholar
• Offit K., Ladanyi M., Gangi M. D., Ebrahim S. A., Filippa D., Chaganti R. S. Ki-1 antigen expression defines a favorable clinical subset of non-B-cell non-Hodgkin's lymphoma. Leukemia 1990; 4: 625–30
   PubMed Web of Science ®Google Scholar
• Sandlund J. T., Pui C. H., Roberts W. M., Santana V. M., Morris S. W., Berard C. W., Hutchison R. E., Ribeiro R. C., Mahmoud H., Crist W. M., Heim M., Raimondi S. C. Clinicopathologic features and treatment outcome of children with large-cell lymphoma and the t(2; 5)(p23; q35). Blood 1994; 84: 2467–71
   PubMed Web of Science ®Google Scholar
• Morris S. W., Kirstein M. N., Valentine M. B., Dittmer K. G., Shapiro D. N., Saltman D. L., Look A. T. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281–4
   PubMed Web of Science ®Google Scholar
• Borer R. A., Lehner C. F., Eppenberger H. M., Nigg E. A. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 1989; 56: 379–90
   PubMed Web of Science ®Google Scholar
• Chan W. Y., Liu Q. R., Borjigin J., Busch H., Rennert O. M., Tease L. A., Chan P. K. Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth. Biochemistry 1989; 28: 1033–9
   PubMed Web of Science ®Google Scholar
• Shiota M., Fujimoto J., Semba T., Satoh H., Yamamoto T., Mori S. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene 1994; 9: 1567–74
   PubMed Web of Science ®Google Scholar
• Shiota M., Fujimoto J., Takenaga M., Satoh H., Ichinohasama R., Abe M., Nakano M., Yamamoto T., Mori S. Diagnosis of t(2; 5)(p23; q35)-associated Ki-1 lymphoma with immunohistochemistry. Blood 1994; 84: 3648–52
   PubMed Web of Science ®Google Scholar
• Waggott W., Lo Y.-M. D., Bastard C., Gatter K. C., Leroux D., Mason D. Y., Boultwood J., Wainscoat J. S. Detection of NPM-ALK DNA rearrangement in CD30 positive anaplastic large cell lymphoma. British J Heamatology 1995; 89: 905–907
   PubMed Web of Science ®Google Scholar
• Morgan R., Smith S. D., Hecht B. K., Christy V., Mellentin J. D., Warnke R., Cleary M. L. Lack of involvement of the c-fms and N-myc genes by chromosomal translocation t(2; 5)(p23; q35) common to malignancies with features of so-called malignant histiocytosis. Blood 1989; 73: 2155–64
   PubMed Web of Science ®Google Scholar
• Fischer P., Nacheva E., Mason D. Y., Sherrington P. D., Hoyle C., Hayhoe F. G., Karpas A. A Ki-1 (CD30)-positive human cell line (Karpas 299) established from a high-grade non-Hodgkin's lymphoma, showing a 2; 5 translocation and rearrangement of the T-cell receptor beta-chain gene. Blood 1988; 72: 234–40
   PubMed Web of Science ®Google Scholar
• Sambrook J., Fritsch E. F., Maniatis T. Expression of Cloned Genes in Escherichia coli. Molecular cloning. A laboratory manual. 1989; Vol. 3: 1989, Cold Spring Harbor Laboratory Press, Plainview, New York), 17. 38–17.39.
   Google Scholar
• Sarris A. H., Luthra L., Papadimitracopoulou V., Dimopoulos M. A., McBride J. A., Cabanillas F., Morris S., Deisseroth A. B., Pugh W. C. A genomic DNA PCR technique demonstrates the presence of the t(2;5) rearrangement in anaplastic large cell lymphoma but no other non-Hodgkin's lymphomas, Hodgkin's disease or lymphomatoid papulosis. Blood 1996; 88: 1771–1779
   PubMed Web of Science ®Google Scholar
• Sarris A. H., Luthra R., Padimitracopoulou V., Waasporp M., Dimopoupos M. A., McBride J. A., Cabanillas F., Duvic M., Deisseroth A., Morris S., Pugh W. Rapid amplification of genomic DNA detects the t(2;5) (p23;q35) in anaplastic large-cell lymphoma, but not in other non-Hodgkin's lymphomas, Hodgkin's disease, or lymphomatoid papulosis. Annals of Oncology 1997, In Press.
   Web of Science ®Google Scholar
• Sarris A. H., Luthra R., Waasdorp M., McBride J. A., Cabanillas F., Duvic M., Chen K., Morris S. W., Pugh W. C. Genomic DNA PCR defines unique t(2;5) breakpoints in anaplastic large cell lymphoma (ALCL). Blood 1996; 88, Suppl 1, Part 2: 143b
   Google Scholar
• Chan P. K., Chan F. Y., Morris S. W., Xhong Z. Isolation and characterization of the human nucleophos-min/B23 (NPM) gene: identification of the YY1 binding site at the 5′ enhancer region. Nucleic Acids Research 1997; 25: 1225–1232
   PubMed Web of Science ®Google Scholar
• Downing J., Shurtleff S., Head D., Behm F., Raimondi S., Weisenburger D., Kossakowska A., Thorner P., Zielenski M., Lorenzana A., Ladanyi M., Morris S. Molecular detection of t(2;5) of Non-Hodgkin's lymphoma by reverse transcriptase polymerase chain reaction (RT-PCR). Modern Pathology 1995; 8: 109A
   PubMedGoogle Scholar
• Lopetagui J. R., Sun L. H., Chan K. C., Gaffey M. J., Frierson H. F., Kamel O. W., Koo C., Glaskin C., Weiss L. M. Association of t(2;5) in CD30-positive anaplastic large cell lymphoma vs Hodgkin's disease. Modern Pathology 1995; 8: 115A
   Google Scholar
• Ngan B. The presence of transcripts of the fusion of kinase gene ALK to nucleophosmin gene NPM in the t(2;5) (p23;q35) translocation defines subsets of non-Hodgkin's lymphoma with or without CD30 (Ki-1) expression and Hodgkin's disease. Modern Pathology 1995; 8: 118A
   Google Scholar
• Wellmann A., Clark H. M., Otsuki T., Jaffe E. S., Raffeld M. Detection of the t(2;5)(p23;q35) in classical anaplastic large cell lymphoma (ALCL) by reverse transcriptase-polymerase chain reaction. Molecular Pathology 1995; 8: 123A
   Google Scholar
• Wellmann A., Otsuki T., Vogelbruch M., Clark H. M., Jaffe E. S., Raffeld M. Analysis of the t(2;5) (p23;q35) Translocation by reverse transciption-polymerase chain reaction in CD30+ anaplastic large-cell lymphomas, in other non-Hodgkin's lymphomas of T-cell phenotype, and in Hodgkin's disease. Blood 1995; 86: 2321–2328
   PubMed Web of Science ®Google Scholar
• Yee H. T., Ponzoni M., Merson A., Scarpa A., Menestrina F., Chilosi M., Pittaluga S., Dewolf-Peeters C., Frizzera G., Ighirami G. Chimeric NPM-ALK transcripts of t(2;5) in anaplastic large cell lymphoma (ALCL) and Hodgkin's disease (HD). Modern Pathology 1995; 8: 124A
   Google Scholar
• Bullrich F., Morris S. W., Hummel M., Pileri S., Stein H., Croce C. M. Nucleophosmin (NPM) gene rearrangements in Ki-1-positive lymphomas. Cancer Res 1994; 54: 2873–7
   PubMed Web of Science ®Google Scholar
• Orscheschek K., Merz H., Hell J., Binder T., Bartels H., Feller A. F. Large-cell anaplastic lymphoma-specific translocation (t[2;S] p23;q35]) in Hodgkin's disease: indication of a common pathogenesis?. The Lancet 1995; 345: 87–90
   PubMed Web of Science ®Google Scholar
• Herbst H., Anagnostopoulos J., Heinze B., DÜRkop H., Hummel M., Stein H. ALK gene products in anaplastic large cell lymphomas and Hodgkin's disease. Blood 1995; 86: 1694–1700
   PubMed Web of Science ®Google Scholar
• Wellman A., Thieblemont C., Fest T., Laszlo K., Jaffe E., Raffeld M. Detection of NMP-ALK rearrangements using an XL (Extra Large)-PCR assay and an analysis of genomic breakpoint sequences. Blood 1996; 88, Suppl 1, Part 1 of 2: 552a
   Google Scholar
• Downing J. R., Shurtleff S. A., Zielenska M., Curcio-Brint A. M., Behm F. G., Head D. R., Sandlund J. T., Weisenburger D. D., Kossakowska A. E., Thorner P., Lorenzana A., Ladanyi M., Morris S. W. Molecular detection of the (2; 5) translocation of Non-Hodgkin's lymphoma by reverse transcriptase-polymerase chain reaction. Blood 1995; 85: 3416–22
   PubMed Web of Science ®Google Scholar
• Shiota M., Nakamura S., Ichinohasama R., Abe M., Akagi T., Takeshita M., Mori N., Fujimoto J., Miyauchi J., Mikata A., Nanba K., Takami T., Yamabe H., Takano Y., Izumo T., Nagatani T., Mohri N., Nasu K., Satoh H., Katano H., Fujimoto J., Yamamoto T., Mori S. Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity. Blood 1995; 86: 1954–1960
   PubMed Web of Science ®Google Scholar
• Elmberger P. G., Lozano M. D., Weisenburger D. D., Sanger W., Chan W. C. Transcripts of the npmalk fusion gene in anaplastic large cell lymphoma, Hodgkin's disease, and reactive lymphoid lesions. Blood 1995; 86: 3517–3521
   PubMed Web of Science ®Google Scholar
• Lamant L., Meggetto F., Al Saati T., Brugieres L., Bressac De Paillerets B., Dastugue N., Bernheim A., Rubie H., Terrier-Lacombe M. J., Robert A., Brousset P., Rigal F., Schlaifer D., Shiota M., Mori S., Deisol G. High incidence of the t(2;5)(23;q35) translocation in anaplastic large cell lymphoma and its lack of detection in Hodgkin's disease. Comparison of cytogenetic analysis, reverse transcriptase-polymerace chain reaction, and p-80 immunostaining. Blood 1996; 87: 284–291
   PubMed Web of Science ®Google Scholar
• Pileri S. A., Piccaluga A., Poggi S., Sabatini E., Piccalugga P. P., De Vivo A., Falini B., Stein H. Anaplastic large cell lymphoma: update of findings. Leukemia and Lymphoma 1995; 18: 17–25
   PubMed Web of Science ®Google Scholar
• De Coteau J. F., Butmarc J. R., Kinney M. C., Kadin M. E. The t(2; 5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large-cell lymphoma of nodal origin. Blood 1996; 87: 3437–41
   PubMed Web of Science ®Google Scholar
• Beylot-Barry M., Lamant L., Vergier B., De Muret A., Fraitag S., Delord B., Dubus P., Vaillant L., Delaunay M., Macgrogan G., Beylot C., De Mascarel A., Deisol G., Merlio J. P. Detection of t(2; 5)(p23; q35) translocation by reverse transcriptase polymerase chain reaction and in situ hybridization in CD30-positive primary cutaneous lymphoma and lymphomatoid papulosis. Am J Pathol 1996; 149: 483–92
   PubMed Web of Science ®Google Scholar
• Pulford K., Lamant L., Morris S. W. H. B. L., Wood K. M., Stroud D., Deisol G., Mason D. Y. Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood 1977; 89: 1394–1404
   Google Scholar
• Weisenburger D. D., Gordon B. G., Vose J. M., Bast M. A., Chan W. C., Greiner T. C., Anderson J. R., Sanger W. G. Occurrence of the t(2; 5)(p23; q35) in non-Hodgkin's lymphoma. Blood 1996; 87: 3860–8
   PubMed Web of Science ®Google Scholar
• Weiss L. M., Lopategui J. R., Sun L.-H., Kamel O. W., Koo C. H., Glackin G. Absence of the t(2;5) in Hodgkin's disease. Blood 1995; 85: 2845–2847
   PubMed Web of Science ®Google Scholar
• Morris S. W., Shurtleff S. A., Head D., Behm F. G., Raimondi S. C., Weisenburger D. D., Kossakowska A. E., Thorner P., Zielenski M., Lorenzana A., Ladanyi M., Downing J. R. Molecular detection of the t(2;5) of Non-Hodgkin's lymphoma (NHL) by reverse transcriptase-polymerase chain reaction. Blood 1994; 84, Suppl 1: 37a
   Web of Science ®Google Scholar