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Original Article

Vitamin D Analogs, Leukemia and WAF1

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Pages 279-284 | Received 17 Dec 1997, Published online: 01 Jul 2009

References

  • Reichel H., Koeffler H. P., Norman A. W. The role of the vitamin D endocrine system in health and disease. N. Engl. J. Med. 1988; 320: 980–991
  • Munker R., Norman A., Koeffler H. P. Vitamin D compounds Effect on clonal proliferation and differentiation of human myeloid. cells. J. Clin. Invest. 1986; 78: 424–430
  • Honma Y., Hozumi M., Abe E., Konno K., Fukushima M., Hata S., Nishii Y., De Luca H. F., Suda T. 1a,25-dihydroxyvitamin D3 and 1a-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells. Proc. Natl. Acad. Sci. USA 1983; 80: 201–204
  • Campbell M. J., Koeffler H. P. Toward therapeutic intervention of cancer by vitamin D compounds. J. Natl. Cancer Inst. 1997; 89: 182–184
  • Suda X., Abe E., Miyaura C. Vitamin D in the differentiation of myeloid leukemia cells, D Vitamin, R. Kumar. Martinus Nijhoff, Boston 1984
  • Baker A. R., McDonnell D. P., Hughes M., Crisp T. M., Mangelsdorf D. J., Haussler M. R., Pike J. W., Shine J., O'Malley B. W. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc. Natl. Acad. Sci. USA 1988; 85: 3294–3298
  • Song L. N. Demonstration of vitamin D receptor expression in a human megakaryoblastic leukemia cell line: regulation of vitamin D receptor mRNA expression and responsiveness by forskolin. J. Steroid Biochem. Molec. Biol. 1996; 57: 265–274
  • Norman A. W., Zhou J. Y., Henry H. L., Uskokovic M. R., Koeffler H. P. Structure-function studies on analogues of 1a,25-dihydroxyvitamin D3: differential effects on leukemic cell growth, differentiation, and intestinal calcium absorption. Cancer Res. 1990; 50: 6857–6864
  • Zhou J. Y., Norman A. W., Lubbert M., Collins E. D., Uskokovic M. R., Koeffler H. P. Novel vitamin D analogs that modulate leukemic cell growth and differentiation with little effect on either intestinal calcium absorption or bone calcium metabolism. Blood 1989; 74: 82–93
  • Elstner E., Lee Y. Y., Hashiya M., Pakkala S., Binderup L., Norman A. W., Okamura W. H., Koeffler H. P. 1a,25-dihydroxy-20-epi-vitamin D3: an extraordinarily potent inhibitor of leukemic cell growth. Blood 1994; 84, 1960-1967
  • Brown A J., Finch J. L., Lopez-Hilker S., Dusso A., Ritter C., Pemalete N., Slatopolsky E. New active analogues of vitamin D with low calcemic activity. Kidney Intern. 1990; 38: S22–S27
  • Bouillon R., Verstuyf A., Zhao J., Tan B. K., Van Baelen H. Nonhypercalcemic vitamin D analogs: interactions with the vitamin D binding proteins. Horm. Res. 1996; 45: 117–121
  • Frankenberger M., Hofmann B., Emmerich B., Nerl C., Schwendener R. A., Ziegler-Heitbrock H. W.L. Liposomal, 1, 25 (OH)2 vitamin D3 compounds block proliferation and induce differentiation in myelomonocytic leukaemia cells. Brit. J. Haematol. 1997; 98: 186–194
  • Zhou J. Y., Norman A. W., Chen D L., Sun G. W., Uskokovic M., Koeffler H. P. 1, 25-dihy-droxy-16-ene-23-yne-vitamin D3 prolongs survival time of leukemic mice. Proc. Natl. Acad. Sci. USA 1990; 87: 3929–3932
  • Hewison M. Vitamin D and the immune system. J. Endocrinol. 1992; 132: 173–175
  • Koeffler H. P. Vitamin D: myeloid differentiation and proliferation. Haematol & Blood Transf. 1985; 29: 409–417
  • Iwata K., Kouttab N., Ogata H., Morgan J. W., Maizel A. L., Lasky S. R. Differential regulation of vitamin D receptors in clonal populations of a chronic myelogenous leukemia cell line. Exp. Cell Res. 1996; 225: 143–145
  • Kikuchi H., Iizuka R., Sugiyama S., Gon G., Mori H., Arai M., Mizumoto K., Imajoh-Ohmi S. Monocytic differentiation modulates apoptotic response to cytotoxic ant-Fas antibody and tumor necrosis factora in human monoblast U937 cells. J. Leukoc. Biol. 1996; 60: 778–783
  • Reitsma P H., Rothberg P. G., Astrin S. M., Trial J., Bar-Shavit Z., Hall A., Teitelbaum S. L., Kahn A. J. Regulation of myc oncogene expression in HL-60 cells by a vitamin D metabolite. Nature 1983; 306: 492–494
  • Yen A., French X., Russell K., Varyavanis S., Forbes M. Vitamin-regulated retinoblastoma tumor suppressor gene expression in leukemic cells. Diet and Cancer:Markers, Prevention, and Treatment, M. M. Jacobs. Plenum Press, New York 1994; 1–18
  • Rebel V. I., Ossenkoppele G. J., Van De Loosdrecht A. A., Wijermans P. W., Beelen R. H.J., Langenhuijsen M. M.A.C. Monocytic differentiation induction of HL-60 cells by MC 903, a novel vitamin D analogue. Leuk. Res. 1992; 16: 443–451
  • Elstner E., Linker-Israeli M., Umiel T., Le J., Grillier I., Said J., Shintaku P., Krajewski S., Reed J. C., Binderup L., Koeffler H. P. Combination of a potent 20-epi-vitamin D3 analogue (KH 1060) with 9-cis-retinoic acid irreversibly inhibits clonal growth, decreases bcl-2 expression, and induces apoptosis in HL-60 leukemic cells. Cancer Res. 1996; 56: 3570–3576
  • Verstuyf A., Mathieu C., Verlinden L., Waer M., Tan B. K., Bouillon R. Differentiation induction of human leukemia cells (HL60) by a combination of 1, 25-dihydroxyvitamin D3 and retinoic acid (all trans or 9-cis). J. Steroid. Bioch. Mol. Biol. 1995; 53: 431–441
  • Defacque H., Sevilla C., Piquemal D., Rochette-Egly C., Marti J., Commes T. Potentiation of VD- induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways. Leukemia 1997; 11: 221–227
  • Studzinski G. P., Bhandal A. K., Brelvi Z. S. Potentiation of 1-a,25-dihydroxy-vitamin D3 of cytotoxicity to HL-60 cells produced by cytarabine and hydroxyurea. J. Natl. Cancer Inst. 1986; 76: 641–648
  • El-Deiry W. S., Tokino T., Velculescu V. E., Levy D. B., Parsons R., Trent J. M., Lin D., Mercer W. E., Kinzler K. W., Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817–825
  • Wang Q. M., Luo X., Studzinski G. P. Cyclin-dependent kinase 6 is the principal target of p27/Kipl regulation of the G1-phase traverse in 1, 25-dihydroxy vitamin D3- treated HL60 cells. Cancer Res 1997; 57: 2851–2855
  • Harper J. W., Adami G. R., Wei N., Keyomarsi K., Elledge S. J. The p21 Cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993; 75: 805–816
  • Zhang W., Komblau S. M., Kobayashi T., Gambel A., Claxton D., Deisseroth A. B. High levels of constitutive WAF1/Cipl protein are associated with chemoresistance in acute myelogenous leukemia. Clin. Cancer Res. 1995; 1: 1051–1057
  • Zhang W., Grasso L., McClain C. D., Gambel A. M., Cha Y., Travali S., Deisseroth A. B., Mercer W. E. p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res. 1995; 55: 668–674
  • Akashi M., Hachiya M., Osawa Y., Spirin K., Suzuki G., Koeffler H. P. Irradiation induces WAF1 expression through a p53-independent pathway in KG-1 cells. J. Biol. Chem. 1995; 270: 19181–19187
  • Jiang H., Lin J., Su Z., Collart F. R., Huberman E., Fisher P. B. Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene 1994; 9: 3397–3406
  • Steinman R. A., Hoffman B., Iro A., Guillouf C., Lieber-Man D. A., El-Houseini M. E. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 1994; 9: 3389–3396
  • Kobayashi T., Consoli U., Andreeff M., Shiku H., Deisseroth A. B., Zhang W. Activation of p21 Waf/CiP1 expression by a temperature-sensitive mutant of human p53 does not lead to apoptosis. Oncogene 1995; 11: 2311–2316
  • Munker R., Kobayashi T., Elstner E., Norman A. W., Uskokovic M., Zhang W., Andreeff M., Koeffler H. P. A new series of vitamin D analogs are highly active for clonal inhibition, differentiation, and induction of WAF1 in myeloid leukemia. Blood 1996; 88: 2201–2209
  • Matsumura I., Ishikawa J., Nakajima K., Oritani K., Tomiyama Y., Miyagawa J. I., Kato T., Miyazaki H., Matsuzawa Y., Kanakura Y. Thrombopoietin- induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21WAF1/Cip1 by STAT5. Mol Cell. Biol. 1997; 17: 2933–2943
  • James S. Y, Mackay A. G., Colston K. W. Effects of 1,25 dihydroxyvitamin D3and its analogues on induction of apoptosis in breast cancer cells. J. Ster. Biochem. Molec. Biol. 1996; 58: 395–401
  • Liu M., Iavarone A., Freedman L. P. Transcriptional activation of the human p21WAF1/Cip1 gene by retinoic acid receptor. Correlation with retinoid induction of U937 differentiation. J. Biol. Chem. 1996; 49: 31723–31728
  • Freemerman A. J., Vrana J. A., Tombes R. M., Jiang H., Chellappan S. P., Fisher P. B., Grant S. Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60). Leukemia 1997; 11: 504–513
  • Koeffler H. P, Hirji K., Itri L., and the Southern California Leukemia Group. 1, 25-Dihydroxyvitamin D3: in vivo and in vitro effects on human preleukaemic and leukaemic cells. Cancer Treatment Reports 1985; 69: 1399–1407

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