177
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Activity of β2-adrenergic receptor in oral squamous cell carcinoma is mediated by overexpression of the ADRBK2 gene: a pilot study

, , , , , & show all
Pages 179-186 | Accepted 05 May 2011, Published online: 15 Sep 2011

References

  • Benovic JL, Pike LJ, Cerione RA, Staniszewski C, Yoshimasa T, Codina J (1985) Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein. J. Biol. Chem. 260: 7094–7101.
  • Benovic JL, Stone WC, Huebner K, Croce C, Caron MG, Lefkowitz RJ (1991) cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase. FEBS Lett. 283: 122–126.
  • Chelmicka-Schorr E, Arnason BG, Holshouser SJ (1980) C-6 glioma growth in rats: suppression with a beta-adrenergic agonist and a phosphodiesterase inhibitor. Ann. Neurol. 8: 447–449.
  • Chiesa IJ, Castillo LF, Luthy IA (2008) Contribution of alpha2-adrenoceptors to the mitogenic effect of catecholestrogen in human breast cancer MCF-7 cells. J. Steroid Biochem. Mol. Biol. 110: 170–175.
  • Cho-Chung YS, Clair T, Tagliaferri P, Ally S, Katsaros D, Tortora G (1989) Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation, and proto-oncogene regulation. Cancer Invest. 7: 161–177.
  • D'Amico C, Crescimanno M, Armata MG, Leonardi V, Palazzoadriano M, D'Alessandro N (1992) Beta-adrenergic influences on doxorubicin-sensitive or -resistant P388 leukemia cells. Anticancer Res. 12: 2253–2256.
  • Drell TL IV, Joseph J, Lang K, Niggemann B, Zaenker KS, Entschladen F (2003) Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells. Breast Cancer Res. Treat. 80: 63–70.
  • Elferink JG, VanUffelen BE (1996) The role of cyclic nucleotides in neutrophil migration. Gen. Pharmacol. 27: 387–393.
  • Entschladen F, Drell TL 4th, Lang K, Joseph J, Zaenker KS (2005) Neurotransmitters and chemokines regulate tumor cell migration: potential for a new pharmacological approach to inhibit invasion and metastasis development. Curr. Pharm. Des. 11: 403–411.
  • Entschladen F, Lang K, Drell TL, Joseph J, Zaenker KS (2002) Neurotransmitters are regulators for the migration of tumor cells and leukocytes. Cancer Immunol. Immunother. 51: 467–482.
  • Fuchs R, Stelzer I, Haas HS, Leitinger G, Schauenstein K, Sadjak A (2009) The alpha1-adrenergic receptor antagonists, benoxathian and prazosin, induce apoptosis and a switch towards megakaryocytic differentiation in human erythroleukemia cells. Ann. Hematol. 88: 989–997.
  • Green DR, Evan GI (2002) A matter of life and death. Cancer Cell 1: 19–30.
  • Hughes RJ, Howard MJ, Allen JM, Insel PA (1991) Decreased beta 2-adrenergic receptor mRNA expression in receptor-deficient S49 lymphoma cells. Mol. Pharmacol. 40: 974–979.
  • Jin Z, Gao F, Flagg T, Deng X (2004a) Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis. J. Biol. Chem. 279: 23837–23844.
  • Jin Z, Gao F, Flagg T, Deng X (2004b) Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. J. Biol. Chem. 279: 40209–40219.
  • Johnson M (2001) Beta2-adrenoceptors: mechanisms of action of beta2-agonists. Paediat. Respir. Rev. 2: 57–62.
  • Kanda H, Ishii K, Ogura Y, Imamura T, Kanai M, Arima K (2008) Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int. J. Cancer 122: 444–451.
  • Kobilka BK, Dixon RA, Frielle T, Dohlman HG, Bolanowski MA, Sigal IS (1987) cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 84: 46–50.
  • Kondratenko TY, Zacharova IV, Kuzina NV, Katukov VY, Severin ES, Kornilova ZC (1993) Alterations in human lung adrenergic receptors in cancer. Biochem. Mol. Biol. Int. 29: 123–130.
  • Lang K, Drell TL, 4th, Lindecke A, Niggemann B, Kaltschmidt C, Zaenker KS (2004) Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int. J. Cancer 112: 231–238.
  • Lange-Carter CA, Droms KA, Vuillequez JJ, Malkinson AM (1992) Differential responsiveness to agents which stimulate cAMP production in normal versus neoplastic mouse lung epithelial cells. Cancer Lett. 67: 139–144.
  • Liou SF, Lin HH, Liang JC, Chen IJ, Yeh JL (2009) Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis. Toxicology 256: 13–24.
  • Luthy IA, Bruzzone A, Pinero CP, Castillo LF, Chiesa IJ, Vazquez SM (2009) Adrenoceptors: non conventional target for breast cancer? Curr. Med. Chem. 16: 1850–1862.
  • Maestroni GJ (2000) Dendritic cell migration controlled by alpha 1b-adrenergic receptors. J. Immunol. 165: 6743–6747.
  • Martinez JA, Corbalan MS, Sanchez-Villegas A, Forga L, Marti A, Martinez-Gonzalez MA (2003) Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism. J. Nutr. 133: 2549–2554.
  • Masur K, Niggemann B, Zanker KS, Entschladen F (2001) Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers. Cancer Res. 61: 2866–2869.
  • Meinhardt G, Wendtner CM, Hallek M (1999) Molecular pathogenesis of chronic lymphocytic leukemia: factors and signaling pathways regulating cell growth and survival. J. Mol. Med. 77: 282–293.
  • Moore MA (2001) The role of chemoattraction in cancer metastases. Bioessays 23: 674–676.
  • Murphy PM (2001) Chemokines and the molecular basis of cancer metastasis. N. Engl. J. Med. 345: 833–835.
  • Narita S, Shibata O, Waki S, Egashira K, Suzuki T (1973) Adrenaline and noradrenaline secretion of the adrenal gland in conscious dogs in response to pilocarpine and nicotine. Tohoku J. Exp. Med. 110: 303–305.
  • Palm D, Lang K, Niggemann B, Drell TL 4th, Masur K, Zaenker KS (2006) The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers. Int. J. Cancer 118: 2744–2749.
  • Park PG, Merryman J, Orloff M, Schuller HM (1995) Beta-adrenergic mitogenic signal transduction in peripheral lung adenocarcinoma: implications for individuals with preexisting chronic lung disease. Cancer Res. 55: 3504–3508.
  • Paul-Eugene N, Dugas B, Gordon J, Kolb JP, Cairns JA, Paubert-Braquet M (1993) Beta 2-adrenoceptor stimulation augments the IL-4-induced CD23 expression and release and the expression of differentiation markers (CD14, CD18) by the human monocytic cell line, U 937. Clin. Exp. Aller. 23: 317–325.
  • Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ (1992) Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms. Biochemistry 31: 3193–3197.
  • Qing F, Hayes MJ, Rhodes CG, Krausz T, Fountain SW, Burke MM (1996) Reduced beta adrenoceptor density in vivo in human lung tumours: a preliminary study with positron emission tomography. Thorax 51: 727–732.
  • Quackenbush J (2002) Microarray data normalization and transformation. Nat. Genet. 32 Suppl.: 496–501.
  • Sastry KS, Karpova Y, Prokopovich S, Smith AJ, Essau B, Gersappe A (2007). Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation. J. Biol. Chem. 282: 14094–14100.
  • Schuller HM, Tithof PK, Williams M, Plummer H 3rd (1999) The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid. Cancer Res. 59: 4510–4515.
  • Shang ZJ, Liu K, Liang de F (2009) Expression of beta2-adrenergic receptor in oral squamous cell carcinoma. J. Oral Pathol. Med. 38: 371–376.
  • Shen SG, Zhang D, Hu HT, Li JH, Wang Z, Ma QY (2008) Effects of alpha-adrenoreceptor antagonists on apoptosis and proliferation of pancreatic cancer cells in vitro. World J. Gastroenterol. 14: 2358–2363.
  • Sheppard JR, Gormus R, Moldow CF (1977) Catecholamine hormone receptors are reduced on chronic lymphocytic leukaemic lymphocytes. Nature 269: 693–695.
  • Silverman EK, Kwiatkowski DJ, Sylvia JS, Lazarus R, Drazen JM, Lange C (2003) Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J. Aller. Clin. Immunol. 112: 870–876.
  • Smyth GK, Yang YH, Speed T (2003) Statistical issues in cDNA microarray data analysis. Methods Mol. Biol. 224: 111–136.
  • Strader CD, Candelore MR, Hill WS, Sigal IS, Dixon RA (1989). Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor. J. Biol. Chem. 264: 13572–13578.
  • Wallukat G (2002) The beta-adrenergic receptors. Herz 27: 683–690.
  • Wang H, Hao B, Chen X, Zhao N, Cheng G, Jiang Y (2006). Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: a case-control study in a Chinese population. Cancer Lett. 240: 297–305.
  • Yang YH, Dudoit S, Luu P, Lin DM, Peng V, Ngai J (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucl. Acids Res. 30: e15.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.