9
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Medication Compliance in Clinical Trials

Pages 47-59 | Published online: 28 Sep 2008

References

  • Cramer J A, Mattson R H. Monitoring compliance with antiepileptic drug therapy. Patient Compliance in Medical Practice and Clinical Trials, J A Cramer, B Spilker. Raven Press, New York 1991b
  • Cramer J A, Collins J F, Mattson R H. Can categorization of patient backgound problems be used to determine early termination in a clinical trial. Controlled Clinical Trials 1988; 9: 47–63
  • Cramer J A. Overview of methods to measure and enhance patient compliance. Patient Compliance in Medical Practice and Clinical Trials, J A Cramer, B Spilker. Raven Press, New York 1991a; 3–10
  • Pullar T, Kumar S, Tindall H, Feely M. Time to stop counting the tablets?. Clin Pharmacol therap 1989; 46: 163–168
  • Rudd P, Byyny R L, Zachary V. The natural history of medication compliance in a drug trial: Limitations of pill counts. Clin Pharmacol therap 1989; 46: 169–176
  • Cramer J A, Mattson R H, Prevey M L, Scheyer R D, Ouellette V L. How often is medication taken as prescribed? A novel assessment technique. JAMA 1989; 261: 3273–3277
  • Cramer J A, Scheyer R D, Mattson R H. Compliance declines between clinic visits. Archives of Internal Medicine 1990; 150: 1377–1378
  • Rand C S, Wise R A, Nides M, Simmons M S, Bleecker E R, Kusek J W, Li V C, Tashkin D P. Metered-dose inhaler adherence in a clinical trial. Am Rev Respir Dis 1992; 146: 1559–1564
  • Nides M A, Tashkin D P, Simmons M S, Wise R A, Li V C, Rand C S. Improving inhaler adherence in a clinical trial through the use of the Nebulizer Chronolog. Chest 1993; 104: 501–507
  • Gonder-Frederick L A, Julian D M, Cox D J, Clarke W L, Carter W R. Self-measurement of blood glucose accuracy of self-reported data and adherence to recommended regimen. Diabetes Care 1988; 2: 579–585
  • Rudd P, Ahmed S, Zachary V, Barton C, Bonduelle D. Compliance with medication timing: Implications from a medication trial for drug development and clinical practice. J Clin Res Pharmacoepidemiol 1992; 6: 15–27
  • Hasford J. Biometric issues in measuring and analyzing partial compliance in clinical trials. Patient Compliance in Medical Practice and Clinical Trials, J A Cramer, B Spilker. Raven Press, New York 1991b; 265–282
  • Pledger G W. Compliance in clinical trials: impact on design, analysis, and interpretation. Epilepsy Research 1988, Suppl 1: 125–133, (eds. D. Schmidt, I Leppik): Compliance in, Epilepsy
  • Feinstein A R. Intent-to-treat policy for analyzing randomized trials: Statistical distortions and neglected clinical challenges. Patient Compliance in Medical Practice and Clinical Trials, J A Cramer, B Spilker. Raven Press, New York 1991b; 359–372
  • Ephron B, Feldman D. Compliance as a explanatory variable in clinical trials. J Am Statistical Assoc 1991; 86: 9–26
  • Vander Stichele R. Measurement of patient compliance and the interpretation of randomized clinical trials. Eur J Clin Pharmacol 1991; 41: 27–35
  • Cramer J A. Feedback on medication dosing enhances patient compliance. Chest 1993; 104: 33–4
  • Friedman R H, Kazis L E, Jette A, Smith M B, Stollerman J, Torgerson J, Carey K. A telecommunications system for monitoring and counseling patients with hypertension: Impact on medication adherence and blood presssure control, (in press)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.