329
Views
31
CrossRef citations to date
0
Altmetric
Original Article

Development of gelatin microspheres loaded with diclofenac sodium for intra-articular administration

, , &
Pages 96-103 | Received 10 Nov 2009, Accepted 26 Feb 2010, Published online: 12 Apr 2010

References

  • Bozdag S, Calis S, Kas HS, Ercan MT, Peksoy I, Hincal AA. (2001). In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium. J Microencapsul, 18, 443–456.
  • Brown KE, Leong K, Huang CH, Dalal R, Green GD, Haimes HB, Jimenez PA, Bathon J. (1998). Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint. Arthritis Rheum, 41, 2185–2195.
  • Carson J, Notis WM, Orris ES. (1990). Colonic ulceration and bleeding during diclofenac therapy. N Engl J Med, 323, 135.
  • Costa P, Sousa Lobo JM. (2001). Modeling and comparison of dissolution profiles. Eur J Pharm Sci, 13, 123–133.
  • Larsen C, Ostergaard J, Larsen SW, Jensen H, Jacobsen S, Lindegaard C, Andersen PH. (2008). Intra-articular depot formulation principles: role in the management of postoperative pain and arthritic disorders. J Pharm Sci, 97, 4622–4654.
  • Öner L, Groves MJ. (1993). Optimization of conditions for preparing 2- to 5-micron-range gelatin microparticles by using chilled dehydration agents. Pharm Res, 10, 621–626.
  • Patrick JS. (2006). Martins Physical Pharmacy and Pharmaceutical Sciences. 5th ed. Baltimore, MD: Lippincott Williams & Wilkins.
  • Pavanetto F, Genta I, Giunchedi P, Conti B, Conte U. (1994). Spray-dried albumin microspheres for the intra-articular delivery of dexamethasone. J Microencapsul, 11, 445–454.
  • Ratcliffe JH, Hunneyball IM, Smith A, Wilson CG, Davis SS. (1984). Preparation and evaluation of biodegradable polymeric systems for the intra-articular delivery of drugs. J Pharm Pharmacol, 36, 431–436.
  • Ratcliffe JH, Hunneyball IM, Wilson CG, Smith A, Davis SS. (1987). Albumin microspheres for intra-articular drug delivery: investigation of their retention in normal and arthritic knee joints of rabbits. J Pharm Pharmacol, 39, 290–295.
  • Saravanan M, Akhilesh Vijay V, Pradeep Kumar PD, Sushma A, Priya S, Maharajan G, Sadasivan Pillai K, Pandey S. (2008a). Comparative studies on diclofenac sodium loaded albumin/gelatin magnetic microspheres for intra-arterial administration. Acta Pharm Sciencia, 50, 189–195.
  • Saravanan M, Anbu J, Maharajan G, Pillai KS. (2008b). Targeted delivery of diclofenac sodium via gelatin magnetic microspheres formulated for intra-arterial administration. J Drug Target, 16, 366–378.
  • Saravanan M, Bhaskar K, Maharajan G, Pillai KS. (2004). Ultrasonically controlled release and targeted delivery of diclofenac sodium via gelatin magnetic microspheres. Int J Pharm, 283, 71–82.
  • Saravanan M, Bhaskar K, Narayanan NV, Maharajan G, Pillai KS. (2003). Diclofenac sodium loaded gelatin magnetic microspheres for intra-arterial administration: formulation, characterization and in vitro release studies. Boll Chim Farm, 142, 347–351.
  • Tunçay M, Calis S, Kas HS, Ercan MT, Peksoy I, Hincal AA. (2000a). In vitro and in vivo evaluation of diclofenac sodium loaded albumin microspheres. J Microencapsul, 17, 145–155.
  • Tunçay M, Calis S, Kas HS, Ercan MT, Peksoy I, Hincal AA. (2000b). Diclofenac sodium incorporated PLGA (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation. Int J Pharm, 195, 179–188.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.